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Predictors of the placebo analgesia response in randomized controlled trials of chronic pain

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The effects of transcranial direct current stimulation in patients with neuropathic pain from spinal cord injury

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Cancer treatment-related neuropathic pain: proof of concept study with menthol—a TRPM8 agonist

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Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations

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Scrambler therapy may relieve chronic neuropathic pain more effectively than guideline-based drug management: results of a pilot, randomized, controlled trial.

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Persistent Postmastectomy Pain and Pain-Related Physical and Emotional Functioning With and Without a Continuous Paravertebral Nerve Block: A Prospective 1-Year Follow-Up Assessment of a Randomized, Triple-Masked, Placebo-Controlled Study

Ilfeld, B. M., Madison, S. J., Suresh, P., Sandhu, N. S., Kormylo, N. J., Malhotra, N., Loland, V. J., Wallace, M. S., Mascha, E. J., Xu, Z., et al. (2014) · Annals of Surgical Oncology · doi:10.1245/s10434-014-4248-7 · Cited by 110 · see citing works

Percutaneous Peripheral Nerve Stimulation (Neuromodulation) for Postoperative Pain: A Randomized, Sham-controlled Pilot Study

Ilfeld, B. M., Plunkett, A., Vijjeswarapu, M. A., Hackworth, R. J., Dhanjal, S. T., Turan, A., Cohen, S. P., Eisenach, J. C., Griffith, S. R., Hanling, S. R., et al. (2021) · Anesthesiology · doi:10.1097/aln.0000000000003776 · Cited by 105 · see citing works

Placebo manipulations reduce hyperalgesia in neuropathic pain

Petersen, G. L., Finnerup, N., Nørskov, K., Grosen, K., Pilegaard, H., Benedetti, F., Price, D., Jensen, T. S., & Vase, L. (2012) · Pain · doi:10.1016/j.pain.2012.03.011 · Cited by 106 · see citing works

Pain severity reduces life quality in chronic pancreatitis: Implications for design of future outcome trials

Olesen, S. S., Juel, J., Nielsen, A. K., Frøkjær, J. B., Wilder‐Smith, O. H. G., & Drewes, A. M. (2014) · Pancreatology · doi:10.1016/j.pan.2014.09.009 · Cited by 104 · see citing works

Alexithymia Is Associated with Greater Risk of Chronic Pain and Negative Affect and with Lower Life Satisfaction in a General Population: The Hisayama Study

Shibata, M., Ninomiya, T., Jensen, M. P., Anno, K., Yonemoto, K., Makino, S., Iwaki, R., Yamashiro, K., Yoshida, T., Imada, Y., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0090984 · Cited by 102 · see citing works

Optimizing and Accelerating the Development of Precision Pain Treatments for Chronic Pain: IMMPACT Review and Recommendations

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Medical and Psychological Risks and Consequences of Long-Term Opioid Therapy in Women

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An Exploratory Human Laboratory Experiment Evaluating Vaporized Cannabis in the Treatment of Neuropathic Pain From Spinal Cord Injury and Disease

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Expectations and positive emotional feelings accompany reductions in ongoing and evoked neuropathic pain following placebo interventions

Petersen, G. L., Finnerup, N. B., Grosen, K., Pilegaard, H. K., Tracey, I., Benedetti, F., Price, D. D., Jensen, T. S., & Vase, L. (2014) · Pain · doi:10.1016/j.pain.2014.09.036 · Cited by 96 · see citing works

Combination of morphine with nortriptyline for neuropathic pain

Gilron, I., Tu, D., Holden, R. R., Jackson, A. C., & Dumerton-Shore, D. (2015) · Pain · doi:10.1097/j.pain.0000000000000149 · Cited by 94 · see citing works

The Use of Ginger ( Zingiber officinale ) for the Treatment of Pain: A Systematic Review of Clinical Trials

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Physiotherapy for pain and disability in adults with complex regional pain syndrome (CRPS) types I and II

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Evidence-based clinical trial design for chronic pain pharmacotherapy: A blueprint for ACTION

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A Trial of Scrambler Therapy in the Treatment of Cancer Pain Syndromes and Chronic Chemotherapy-Induced Peripheral Neuropathy

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Effectiveness and Safety of Dorsal Root Ganglion Stimulation for the Treatment of Chronic Pain: A Pooled Analysis

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Effectiveness of cognitive behaviour therapy for the treatment of catastrophisation in patients with fibromyalgia: A randomised controlled trial

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Patterns of cutaneous nerve fibre loss and regeneration in type 2 diabetes with painful and painless polyneuropathy

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A comparison of the clinical and experimental characteristics of four acute surgical pain models: Dental extraction, bunionectomy, joint replacement, and soft tissue surgery

Singla, N., Desjardins, P. J., & Chang, P. D. (2013) · Pain · doi:10.1016/j.pain.2013.09.002 · Cited by 76 · see citing works

Mechanisms of pain in distal symmetric polyneuropathy: A combined clinical and neurophysiological study

Truini, A., Biasiotta, A., Cesa, L. S., Stefano, G. D., Galeotti, F., Petrucci, M., Inghilleri, M., Cartoni, C., Pergolini, M., & Cruccu, G. (2010) · Pain · doi:10.1016/j.pain.2010.06.006 · Cited by 74 · see citing works

Research design considerations for randomized controlled trials of spinal cord stimulation for pain: Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials/Institute of Neuromodulation/International Neuromodulation Society recommendations

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Lumbar Transforaminal Epidural Dexamethasone

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Answer to the Letter to the Editor of Koen Van Boxem et al. concerning manuscript “Injection therapy and denervation procedures for chronic low-back pain: a systematic review” by Henschke N, Kuijpers T, Rubinstein SM, van Middelkoop M, Ostelo R, Verhagen A, Koes BW, van Tulder MW, Eur Spine J, 2010

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Core outcome measures for opioid abuse liability laboratory assessment studies in humans: IMMPACT recommendations

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The design and conduct of clinical trials to limit missing data

Little, R. J. A., Cohen, M. L., Dickersin, K., Emerson, S. S., Farrar, J. T., Neaton, J. D., Shih, W. J., Siegel, J. P., & Stern, H. S. (2012) · Statistics in Medicine · doi:10.1002/sim.5519 · Cited by 70 · see citing works

The Chalder Fatigue Questionnaire is a valid and reliable measure of perceived fatigue severity in multiple sclerosis

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Pain in pancreatic ductal adenocarcinoma: A multidisciplinary, International guideline for optimized management

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Opioid use in chronic noncancer pain: guidelines revisited

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Compression Hosiery for Occupational Leg Symptoms and Leg Volume: A Randomized Crossover Trial in a Cohort of Hairdressers

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Adherence to CONSORT harms-reporting recommendations in publications of recent analgesic clinical trials: An ACTTION systematic review

Smith, S. M., Chang, D. R., Pereira, A. C., Shah, N., Gilron, I., Katz, N. P., Lin, A. H., McDermott, M., Rappaport, B. A., Rowbotham, M. C., et al. (2012) · Pain · doi:10.1016/j.pain.2012.08.009 · Cited by 65 · see citing works

Tai Chi and Chronic Pain

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Randomized trial of the effect of mindfulness-based stress reduction on pain-related disability, pain intensity, health-related quality of life, and A1C in patients with painful diabetic peripheral neuropathy

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Integration of Pain Score and Morphine Consumption in Analgesic Clinical Studies

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Mechanisms of chronic pain – key considerations for appropriate physical therapy management

Courtney, C. A., Fernández‐de‐las‐Peñas, C., & Bond, S. (2017) · Journal of Manual & Manipulative Therapy · doi:10.1080/10669817.2017.1300397 · Cited by 59 · see citing works

Local anaesthetic sympathetic blockade for complex regional pain syndrome

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IMPROVE trial: A randomized controlled trial of patient-controlled analgesia for sickle cell painful episodes: rationale, design challenges, initial experience, and recommendations for future studies

Dampier, C., Smith, W. R., Wager, C. G., Kim, H.-Y., Bell, M. C., Miller, S. T., Weiner, D. L., Minniti, C. P., Krishnamurti, L., Ataga, K. I., et al. (2013) · Clinical Trials · doi:10.1177/1740774513475850 · Cited by 58 · see citing works

Efficacy and tolerability of buccal buprenorphine in opioid-experienced patients with moderate to severe chronic low back pain: results of a phase 3, enriched enrollment, randomized withdrawal study

Gimbel, J. S., Spierings, E. L. H., Katz, N. P., Xiang, Q., Tzanis, E. L., & Finn, A. L. (2016) · Pain · doi:10.1097/j.pain.0000000000000670 · Cited by 57 · see citing works

Role of metformin in oxaliplatin-induced peripheral neuropathy in patients with stage III colorectal cancer: randomized, controlled study

El-fatatry, B. M., Ibrahim, O. M., Hussein, F. Z., & Mostafa, T. M. (2018) · International Journal of Colorectal Disease · doi:10.1007/s00384-018-3104-9 · Cited by 58 · see citing works

Effectiveness of a treadmill-based aerobic exercise intervention on pain, daily functioning, and quality of life in women with primary dysmenorrhea: A randomized controlled trial.

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Comparison of Acupuncture vs Sham Acupuncture or Waiting List Control in the Treatment of Aromatase Inhibitor–Related Joint Pain

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Improving Study Conduct and Data Quality in Clinical Trials of Chronic Pain Treatments: IMMPACT Recommendations

Gewandter, J. S., Dworkin, R. H., Turk, D. C., Devine, E. G., Hewitt, D., Jensen, M. P., Katz, N. P., Kirkwood, A. A., Malamut, R. I., Markman, J. D., et al. (2019) · Journal of Pain · doi:10.1016/j.jpain.2019.12.003 · Cited by 56 · see citing works

Diabetes is associated with persistent pain after hip and knee replacement

Rajamäki, T. J., Jämsen, E., Puolakka, P. A., Nevalainen, P. I., & Moilanen, T. P. S. (2015) · Acta Orthopaedica · doi:10.3109/17453674.2015.1044389 · Cited by 57 · see citing works

Clinical experience with duloxetine in the management of chronic musculoskeletal pain. A focus on osteoarthritis of the knee

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A randomized, double-blind, placebo-controlled trial and open-label extension study to evaluate the efficacy and safety of pregabalin in the treatment of neuropathic pain associated with human immunodeficiency virus neuropathy

Simpson, D. M., Rice, A. S. C., Emir, B., Landen, J. W., Semel, D., Chew, M. L., & Sporn, J. (2014) · Pain · doi:10.1016/j.pain.2014.05.027 · Cited by 54 · see citing works

Treatment of Postmastectomy Pain With Ambulatory Continuous Paravertebral Nerve Blocks

Ilfeld, B. M., Madison, S. J., Suresh, P., Sandhu, N. S., Kormylo, N. J., Malhotra, N., Loland, V. J., Wallace, M. S., Proudfoot, J. A., Morgan, A. C., et al. (2014) · Regional Anesthesia & Pain Medicine · doi:10.1097/aap.0000000000000035 · Cited by 55 · see citing works

Efficacy and safety of flupirtine modified release for the management of moderate to severe chronic low back pain: results of SUPREME, a prospective randomized, double-blind, placebo- and active-controlled parallel-group phase IV study

Ueberall, M. A., Mueller-Schwefe, G. H. H., & Terhaag, B. (2012) · Current Medical Research and Opinion · doi:10.1185/03007995.2012.726216 · Cited by 54 · see citing works

Yoga for chronic chemotherapy-induced peripheral neuropathy pain: a pilot, randomized controlled trial

Knoerl, R., Giobbie‐Hurder, A., Berfield, J., Berry, D. L., Meyerhardt, J. A., Wright, A. A., & Ligibel, J. A. (2021) · Journal of Cancer Survivorship · doi:10.1007/s11764-021-01081-z · Cited by 53 · see citing works

The efficacy of duloxetine, non-steroidal anti-inflammatory drugs, and opioids in osteoarthritis: a systematic literature review and meta-analysis

Myers, J. A., Wielage, R. C., Han, B., Price, K., Gahn, J. C., Paget, M.-A., & Happich, M. (2014) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-15-76 · Cited by 52 · see citing works

Intrathecal Gabapentin to Treat Chronic Intractable Noncancer Pain

Rauck, R. L., Coffey, R. J., Schultz, D. M., Wallace, M. S., Webster, L. R., McCarville, S., Grigsby, E. J., & Page, L. M. (2013) · Anesthesiology · doi:10.1097/aln.0b013e3182a10fbf · Cited by 51 · see citing works

Preoperative Ultrasound-guided Percutaneous Cryoneurolysis for the Treatment of Pain after Mastectomy: A Randomized, Participant- and Observer-masked, Sham-controlled Study

Ilfeld, B. M., Finneran, J. J., Swisher, M. W., Said, E. T., Gabriel, R. A., Sztain, J. F., Khatibi, B., Armani, A., Trescot, A. M., Donohue, M., et al. (2022) · Anesthesiology · doi:10.1097/aln.0000000000004334 · Cited by 50 · see citing works

Pragmatic trials of pain therapies: a systematic review of methods

Hohenschurz‐Schmidt, D., Kleykamp, B. A., Draper‐Rodi, J., Vollert, J., Chan, J., Ferguson, M. C., McNicol, E. D., Phalip, J., Evans, S. R., Turk, D. C., et al. (2021) · Pain · doi:10.1097/j.pain.0000000000002317 · Cited by 49 · see citing works

Long-Term Effects of Interprofessional Biopsychosocial Rehabilitation for Adults with Chronic Non-Specific Low Back Pain: A Multicentre, Quasi-Experimental Study

Semrau, J., Hentschke, C., Buchmann, J., Meng, K., Vogel, H., Faller, H., Bork, H., & Pfeifer, K. (2015) · PLoS ONE · doi:10.1371/journal.pone.0118609 · Cited by 48 · see citing works

Ambulatory continuous peripheral nerve blocks to treat postamputation phantom limb pain: a multicenter, randomized, quadruple-masked, placebo-controlled clinical trial

Ilfeld, B. M., Khatibi, B., Maheshwari, K. K., Madison, S. J., Esa, W. A. S., Mariano, E. R., Kent, M. L., Hanling, S. R., Sessler, D. I., Eisenach, J. C., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000002087 · Cited by 48 · see citing works

Mindfulness‐based stress reduction and cognitive function among breast cancer survivors: A randomized controlled trial

Duval, A., Davis, C. G., Khoo, E., Romanow, H. C., Shergill, Y., Rice, D. B., Smith, A., Poulin, P. A., & Collins, B. (2022) · Cancer · doi:10.1002/cncr.34209 · Cited by 48 · see citing works

A Policy-into-Practice Intervention to Increase the Uptake of Evidence-Based Management of Low Back Pain in Primary Care: A Prospective Cohort Study

Slater, H., Davies, S., Parsons, R. W., Quintner, J. L., & Schug, S. A. (2012) · PLoS ONE · doi:10.1371/journal.pone.0038037 · Cited by 48 · see citing works

Multicenter, Randomized, Double-Blind Study Protocol Using Human Spinal Cord Recording Comparing Safety, Efficacy, and Neurophysiological Responses Between Patients Being Treated With Evoked Compound Action Potential–Controlled Closed-Loop Spinal Cord Stimulation or Open-Loop Spinal Cord Stimulation (the Evoke Study)

Levy, R. M., Deer, T. R., Poree, L. R., Rosen, S. M., Kapural, L., Amirdelfan, K., Soliday, N., Leitner, A., & Mekhail, N. A. (2019) · Neuromodulation Technology at the Neural Interface · doi:10.1111/ner.12932 · Cited by 48 · see citing works

Essential statistical principles of clinical trials of pain treatments

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8. Herpes zoster and post herpetic neuralgia

Adriaansen, E. J. M., Jacobs, J. G., Vernooij, L. M., van Wijck, A. J. M., Cohen, S. P., Huygen, F. J. P. M., & Rijsdijk, M. (2024) · Pain Practice · doi:10.1111/papr.13423 · Cited by 53 · see citing works

Efficacy and Safety of Pregabalin in Patients with Fibromyalgia and Comorbid Depression Taking Concurrent Antidepressant Medication: A Randomized, Placebo-controlled Study

Arnold, L. M., Sarzi‐Puttini, P., Arsenault, P., Khan, T. M., Brown, P. B., Clair, A. G., Scavone, J. M., Driscoll, J., Landen, J. W., & Pauer, L. (2015) · The Journal of Rheumatology · doi:10.3899/jrheum.141196 · Cited by 46 · see citing works

Mechanism- and experience-based strategies to optimize treatment response to the capsaicin 8% cutaneous patch in patients with localized neuropathic pain

Treede, R., Wagner, T., Kern, K., Husstedt, I., Arendt, G., Birklein, F., Cegla, T. H., Freynhagen, R., Gockel, H.-H., Heskamp, M. ‐. S., et al. (2013) · Current Medical Research and Opinion · doi:10.1185/03007995.2013.781019 · Cited by 45 · see citing works

Treating Intractable Phantom Limb Pain with Ambulatory Continuous Peripheral Nerve Blocks: A Pilot Study

Ilfeld, B. M., Moeller‐Bertram, T., Hanling, S. R., Tokarz, K. A., Mariano, E. R., Loland, V. J., Madison, S. J., Ferguson, E. J., Morgan, A. C., & Wallace, M. S. (2013) · Pain Medicine · doi:10.1111/pme.12080 · Cited by 44 · see citing works

The Effect of Intraoperative Systemic Lidocaine on Postoperative Persistent Pain Using Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials Criteria Assessment Following Breast Cancer Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Trial

Kendall, M. C., McCarthy, R. J., Panaro, S., Goodwin, E. J., Bialek, J. M., Nader, A., & Oliveira, G. S. D. (2017) · Pain Practice · doi:10.1111/papr.12611 · Cited by 44 · see citing works

An Investigation of Factors Contributing to Higher Levels of Placebo Response in Clinical Trials in Neuropathic Pain: A Systematic Review and Meta-Analysis

Arakawa, A., Kaneko, M., & Narukawa, M. (2015) · Clinical Drug Investigation · doi:10.1007/s40261-014-0259-1 · Cited by 43 · see citing works

Comparative Effectiveness of Cognitive Behavioral Therapy for Chronic Pain and Chronic Pain Self-Management within the Context of Voluntary Patient-Centered Prescription Opioid Tapering: The EMPOWER Study Protocol

Darnall, B. D., Mackey, S., Lorig, K. R., Kao, M. J., Mardian, A. S., Stieg, R. L., Porter, J., DeBruyne, K., Murphy, J. L., Perez, L., et al. (2019) · Pain Medicine · doi:10.1093/pm/pnz285 · Cited by 43 · see citing works

Prevention of chronic post-surgical pain: the importance of early identification of risk factors

Tawfic, Q. A., Kumar, K., Pirani, Z., & Armstrong, K. (2017) · Journal of Anesthesia · doi:10.1007/s00540-017-2339-x · Cited by 44 · see citing works

Assessment of postoperative pain – need for action!

Kehlet, H., & Dahl, J. B. (2011) · Pain · doi:10.1016/j.pain.2011.03.013 · Cited by 42 · see citing works

Phenotyping neuropathic pain patients

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Considerations for improving assay sensitivity in chronic pain clinical trials: IMMPACT recommendations

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