Impact of a primary care-based mobile health intervention to ‘sit less and move more’ on HbA1c, blood pressure, and other clinical outcomes in office employees with type 2 diabetes: A randomized controlled trial
Open accessAbstract
BACKGROUND: Type 2 diabetes (T2D) is a prevalent and costly disease, with sedentary behaviour and physical inactivity as modifiable contributors. Mobile health (mHealth) applications provide complementary strategies for T2D management, but their impact on clinical outcomes remains unclear. OBJECTIVE: This study evaluated the efficacy of an mHealth programme promoting "sit less and move more" at work, prescribed in clinical practice, on clinical and cardiovascular risk factors in office employees with T2D. METHODS: A randomized controlled trial compared usual care (n = 25) with a 13-week mHealth intervention (n = 29) using the Walk@Work-App and web-based tools. Outcomes included HbA1c, glycemia, lipid profile, domain-specific sedentary behaviour (Workforce Sitting Questionnaire), objective physical activity and sedentary behaviour (ActivPal), blood pressure, and BMI at baseline, 6, and 12 months. RESULTS: Compared to the control group and at 12 months, the intervention group showed a significant reduction in HbA1c (p < 0.05), systolic and diastolic blood pressure (p < 0.05). Sitting time decreased during leisure activities while watching TV (p = 0.0052) and using electronic devices (p = 0.0397). The number of sedentary breaks and time spent in sedentary bouts <20 min/day increased (p < 0.05). CONCLUSIONS: An mHealth programme effectively reduced sedentary behaviour, improved HbA1c and blood pressure, serving as a cost-effective lifestyle intervention for adults with T2D. TRIAL REGISTRATION: ClinicalTrials.gov NCT04092738.https://clinicaltrials.gov/ct2/show/NCT04092738.
AI snapshot
Written from the paper’s full text.
TL;DR
A primary care-prescribed 13-week mHealth programme promoting “sit less and move more” at work improved HbA1c and blood pressure at 12 months in office employees with type 2 diabetes compared with usual care. It also reduced several sedentary behaviour domains, though the trial was underpowered because COVID-19 curtailed recruitment.
Key findings
- At 12 months, the intervention group showed significant reductions versus control in HbA1c (≤−0.5%, p<0.01; maximum between-group difference 0.50% reduction) and in systolic and diastolic blood pressure (p<0.05; maximum SBP difference 8.82 mmHg reduction).
- Sitting time decreased in leisure domains, including while watching TV (p=0.0052) and using electronic devices (p=0.0397); sitting at work fell by 45.63 min/day at 6 months (p<0.01) and 26.25 min/day at 12 months (p<0.05).
- Objective sedentary behaviour at 3 months (16 measurements: 9 control, 7 intervention) showed greater sedentary breaks in the intervention group (average increase 7.7 breaks/day vs 1.69 breaks/day), mainly from breaks <20 min; time spent in sedentary bouts <20 min/day decreased more in the intervention group (p=0.0328).
- No significant between-group differences were found for total cholesterol, HDL cholesterol, LDL cholesterol, or triglycerides; BMI improved in the intervention group compared with control.
Methods
- Parallel, single-blind randomized controlled trial in 54 adults with type 2 diabetes (29 intervention, 25 usual care), recruited from three primary health care centres in Barcelona between March and April 2019; eligibility required office work with ≥55% of daily working hours sedentary (OSPAQ), a smartphone, and a work contract of at least 18.5 h/week.
- The intervention was a 13-week Walk@Work-App mHealth programme using a MetaWearC thigh sensor, self-monitoring, feedback, goal setting, and ramping/maintenance phases to reduce and break occupational sitting and increase movement; controls received usual care.
- Outcomes were measured at baseline, 6, and 12 months (HbA1c, glucose, lipids, blood pressure, BMI; Workforce Sitting Questionnaire for domain-specific sitting) and with activPAL at baseline and 3 months; analysis used descriptive statistics, baseline homogeneity tests, and one-tailed t tests of within-person differences between groups.
Limitations
- The paper states the main limitation was sample size: recruitment was suspended because of the COVID-19 pandemic, losses were 45% higher than initially estimated, some participants were excluded when follow-up coincided with the pandemic, and statistical power was lower than desired (0.69 two-sided, 0.80 one-sided with the final sample of 54).
- The paper states objective sedentary behaviour and physical activity at 3 months had only 16 measurements (9 control, 7 intervention) due to technical and logistical difficulties in primary care, so those results should be considered approximations.
- The paper notes professionals could not be blinded to the mHealth intervention and intervention patients may have had more visits with health professionals; no differences in medication or diet changes were observed between groups.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
18 of 26 cited sources checked · 4 supported · 0 flagged · accuracy not yet measured
- Premisecitation
Mobile applications that include promotion of physical activity with automatic data transfer play an important role in type 2 diabetes self-management.
“Despite the few studies of mobile applications where the main focus of the intervention is the pattern of physical activity and SB, mobile applications that include the promotion of physical activity, with automatic data transfer that promote motivation and increase physical activity have been shown to play an important role in T2D self-management [37].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [37] Årsand, 2012, Mobile health applications to assist patients with diabetes: lessons learned and design implications, J. Diabetes Sci. Technol. source
The “Physical Activity Monitoring for Type 2 Diabetes” section (page not specified) describes automatic transfer of step counts and says users liked the system’s motivational feedback. The “Mobile Phone-Based Diabetes Diary for Type 2 Diabetes” section (page not specified) describes its role in T2D self-management, but reports usability and acceptance—not a demonstrated increase in physical activity. The citing sentence overstates that outcome. (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Interpretationcitation
The increase in sedentary breaks, mainly breaks <20 min, can justify the clinical improvements observed.
“In our results there was a greater number of SB breaks in the intervention group, increasing 7.7 interruptions/day, mainly due to the increase in interruptions in periods of time less than 20 min, modifying the characteristic pattern in adults with T2D compared to adults without T2D [11], which can justify the results in the clinical improvements.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [11] Colomer, 2022, Differences in free-living patterns of sedentary behaviour between office employees with diabetes and office employees without diabetes: a principal component analysis for clinical practice, Int. J. Environ. Res. Public Health source
- Premisecitation
Adults with type 2 diabetes have a pattern of sedentary behaviour different from adults without diabetes, characterized by fewer daily sedentary breaks and less time sitting in short periods of less than 20 min.
“Adults with T2D have shown to have a pattern of SB that is different from adults without diabetes [11], characterized by having fewer daily SB interruptions and spending less time sitting in short periods of less than 20 min [11].”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [11] Colomer, 2022, Differences in free-living patterns of sedentary behaviour between office employees with diabetes and office employees without diabetes: a principal component analysis for clinical practice, Int. J. Environ. Res. Public Health source
The Results (§3.1) report that participants with T2D took fewer daily sedentary breaks and spent less time in sedentary periods under 20 minutes than participants with normal glucose metabolism. The claim generalizes this finding to adults broadly, whereas the study examined office employees. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Premisecitation
Prescription of mHealth programmes from healthcare practice is scarce due to the lack of randomized controlled trials that determine their effectiveness on clinical outcomes.
“However, the prescription of mHealth programmes from healthcare practice is scarce due to the lack of randomized controlled trials that determine their effectiveness on clinical outcomes [16,17].”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [16] Veazie, 2018, Rapid evidence review of mobile applications for self-management of diabetes, J. Gen. Intern. Med. source
The Summary of Evidence and Conclusion and Next Steps (pages unavailable) describe limited evidence for commercially available diabetes apps and call for more rigorous, longer-term studies of clinical outcomes. The paper does not say that prescribing mHealth programmes in healthcare practice is scarce or that a shortage of randomized trials causes scarce prescribing; its Apps for Type 2 Diabetes section reports six randomized controlled trials. (LLM, conf=0.86)
Experimental — accuracy not yet measured - cites [17] Bonn, 2018, App-technology to increase physical activity among patients with diabetes type 2 the diacert-study, a randomized controlled trial, BMC Public Health source
The Background (page not provided) identifies a narrower evidence gap: the reviewed studies of physical-activity apps included no patients with type 2 diabetes. It does not say that healthcare practitioners rarely prescribe mHealth programmes or that a lack of randomized trials measuring clinical outcomes causes such scarcity. (LLM, conf=0.73)
Experimental — accuracy not yet measured
- Premisecitation
The effect of technology-based interventions in patients with type 2 diabetes on long-term clinical parameters is described in other studies, where the effects were not maintained at 12 months.
“The effect of technology-based interventions in patients with T2D on long-term clinical parameters is described in other studies, where the effects were not maintained at 12 months [36,38].”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [36] Holmen, 2014, A mobile health intervention for self-management and lifestyle change for persons with type 2 diabetes, part 2: one-year results from the norwegian randomized controlled trial RENEWING HEALTH, JMIR mhealth uhealth source
The Discussion reports no significant difference in HbA1c change between intervention and control groups after one year, supporting the claim that a clinical benefit was not evident at 12 months. It does not establish that an earlier intervention benefit was lost; it says mean HbA1c remained below baseline in all three groups. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [38] Varney, 2014, Effect of hospital-based telephone coaching on glycaemic control and adherence to management guidelines in type 2 diabetes, a randomised controlled trial, Intern. Med. J. source
- Premisecitation
The majority of mobile applications for type 2 diabetes management focus solely on blood glucose measurement/control or combine it with diet, blood pressure control, weight or physical activity in a not very detailed way.
“Despite this, the majority of mobile applications for the management of T2D focus solely on the measurement and control of blood glucose or in combination with diet, blood pressure control and weight or physical activity in a way that is not very detailed [35,36].”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites [35] Bonoto, 2017, Efficacy of mobile apps to support the care of patients with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials, JMIR mhealth uhealth source
The Results (Characteristics of Studies and Participants; Subgroup Analysis, pages unavailable) describe apps with blood-glucose, diet, and exercise features. They do not establish that most type 2 diabetes apps focus solely on glucose or cover other activities in little detail; the reviewed apps also had medication-management and clinician-communication features. The cited passages do not identify blood-pressure control as an app feature. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites [36] Holmen, 2014, A mobile health intervention for self-management and lifestyle change for persons with type 2 diabetes, part 2: one-year results from the norwegian randomized controlled trial RENEWING HEALTH, JMIR mhealth uhealth source
The Discussion says blood glucose measurement is the most frequent component of mobile diabetes apps and that key components and education are often lacking. It does not establish that a majority focus solely on glucose or assess how detailed their diet, blood-pressure, weight, or physical-activity features are. (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Premisecitation
Previous studies have reported a greater effect of longer interventions compared to shorter ones.
“Previous studies [39,40] have reported a greater effect of longer interventions compared to shorter ones [41].”
Quote in the paperNot a substantial claim2 of 3 sources checked- cites [39] Ashe, 2015, "Not just another walking program": everyday activity supports You (EASY) model-a randomized pilot study for a parallel randomized controlled trial, Pilot Feasibility Stud. source
The Results section compares outcomes at three and six months within the same EASY intervention, but does not compare longer interventions with shorter ones. Searches for the claimed duration–effect relationship found no passage in our copy that reports it. (LLM, conf=0.74)
Experimental — accuracy not yet measured - cites [40] Lyons, 2017, Feasibility and acceptability of a wearable technology physical activity intervention with telephone counseling for mid-aged and older adults: a randomized controlled pilot trial, JMIR mhealth uhealth source
The Methods (Procedure; page unavailable) describe a 12-week intervention, and the Results report its effects at 12 weeks. Neither those passages nor the Discussion (Principal Findings; page unavailable) compares longer interventions with shorter ones. Searches for intervention duration and greater effects found no passage reporting the attributed comparison. (LLM, conf=0.75)
Experimental — accuracy not yet measured - cites [41] Bickmore, 2013, A randomized controlled trial of an automated exercise coach for older adults, J. Am. Geriatr. Soc. source
- Premisecitation
Interventions that combine personal advice are more successful than a mobile application alone.
“A systematic review of the effectiveness of interventions that use applications to improve diet, physical activity and SB found evidence that interventions that combine personal advice were more successful than a mobile application alone [44].”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [44] Schoeppe, 2016, Efficacy of interventions that use apps to improve diet, physical activity and sedentary behaviour: a systematic review, Int. J. Behav. Nutr. Phys. Act. source
The Conclusions say that interventions combining apps with other strategies appear more effective than stand-alone apps, but add that this needs testing in controlled trials. The Discussion likewise reports more significant improvements among multi-component interventions without establishing that personal advice specifically was the effective added component. The claim is more definite and more specific than the review's finding. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Premisecitation
Modifying the characteristic sedentary patterns of adults with type 2 diabetes could tackle a modifiable risk factor for type 2 diabetes that is scarcely addressed from clinical practice.
“Modifying these characteristic sedentary patterns of adults with T2D could tackle a modifiable risk factor for T2D [12] that is scarcely addressed from clinical practice, which mainly focuses on increasing moderate and vigorous activity [13].”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [12] Alòs, , Incorporating objective measures of sedentary behaviour into the detection and control methods of type 2 diabetes mellitus: development of a mathematical model for clinical practice, Submitted.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [13] Hamilton, 2014, Sedentary behavior as a mediator of type 2 diabetes, Med. Sport. Sci. source
- Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention increased time spent in sedentary bouts <20 min/day (p < 0.05).
“The number of sedentary breaks and time spent in sedentary bouts <20 min/day increased (p < 0.05).”
- Also stated in: § 3.3. Study outcomes · plain
“These differences were due to an increase in interruptions during periods of less than 20 min (see Table 5).”
Quote in the paperSubstantial claim - Also stated in: § 3.3. Study outcomes · plain
- Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention reduced sedentary time using a computer, tablet or smartphone at home on non-workdays (p < 0.05).
“A significant reduction was also identified in sedentary time using a computer, tablet or smartphone at home on non-workdays (p < 0.05) and while doing other sedentary leisure activities on workdays of 10 min/day and 22 min/day at the 6-(p < 0.05) and 12-month follow-ups (p < 0.05), respectively (see Table 6).”
Quote in the paperSubstantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention increased the number of sedentary breaks (p < 0.05).
“The number of sedentary breaks and time spent in sedentary bouts <20 min/day increased (p < 0.05).”
- Also stated in: § 3.3. Study outcomes · plain
“There was a greater number of SB breaks in the intervention group, with an average increase of 7.7 breaks/day, while in the control group the increase was 1.69 breaks/ day.”
Quote in the paperSubstantial claim - Also stated in: § 3.3. Study outcomes · plain
- Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention reduced sitting time while at work at 6 months by 45.63 min/day (p < 0.01).
“Compared to the control group and with regards to the sedentary time spent in different domains, significant differences were observed in the reduction of sitting time while at work of 45.63 min/day and 26.25 min/day at the 6-(p < 0.01) and 12-month follow-ups (p < 0.05), respectively.”
Quote in the paperSubstantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention produced a significant reduction in diastolic blood pressure at 12 months (p < 0.05).
“Compared to the control group and at 12 months, the intervention group showed a significant reduction in HbA1c (p < 0.05), systolic and diastolic blood pressure (p < 0.05).”
- Also stated in: § 3.3. Study outcomes · plain
“In comparison with the control group, participants in the intervention group had significant and clinically relevant reductions in glycated hemoglobin (HbA1c; ≤-0.5 %, p < 0.01) and in SBP and DBP (p < 0.05) at the 12-month follow-up (see Table 4).”
Quote in the paperSubstantial claim - Also stated in: § 3.3. Study outcomes · plain
- Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention reduced sitting time while using electronic devices (p = 0.0397).
“Sitting time decreased during leisure activities while watching TV (p = 0.0052) and using electronic devices (p = 0.0397).”
Quote in the paperSubstantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention produced a significant reduction in HbA1c at 12 months (about 0.5 percentage points; p < 0.05/0.01).
“In comparison with the control group, participants in the intervention group had significant and clinically relevant reductions in glycated hemoglobin (HbA1c; ≤-0.5 %, p < 0.01) and in SBP and DBP (p < 0.05) at the 12-month follow-up (see Table 4).”
Quote in the paperSubstantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention reduced sitting time during leisure activities while watching TV (p = 0.0052).
“Sitting time decreased during leisure activities while watching TV (p = 0.0052) and using electronic devices (p = 0.0397).”
Quote in the paperSubstantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention reduced sitting time while at work at 12 months by 26.25 min/day (p < 0.05).
“Compared to the control group and with regards to the sedentary time spent in different domains, significant differences were observed in the reduction of sitting time while at work of 45.63 min/day and 26.25 min/day at the 6-(p < 0.01) and 12-month follow-ups (p < 0.05), respectively.”
Quote in the paperSubstantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention improved BMI.
“The BMI results improved in the intervention group compared to the control group (see Table 4).”
Quote in the paperNot a substantial claim - Findingown data
No statistically significant differences in diet changes were observed between the intervention and control groups at the 3-, 6-, and 12-month follow-ups (p=0.1342, p=0.5595, p=0.1596).
“Regarding changes in diet, there were no statistically significant differences between the two groups at the 3-, 6-, and 12-month follow-ups (p-value < 0.1342, p-value = 0.5595, and p-value = 0.1596, respectively).”
Quote in the paperNot a substantial claim - Findingown data
No differences in medication (insulinization and number of oral antibiotics) were observed between the intervention and control groups during the intervention and follow-up period.
“No differences in medication (insulinization and number of oral antibiotics) or changes in diet were observed between the groups during the intervention and follow-up period.”
Quote in the paperNot a substantial claim - Findingown data
In office employees with type 2 diabetes, compared with usual care, the mHealth intervention reduced sedentary time while doing other sedentary leisure activities on workdays by 10 min/day at 6 months and 22 min/day at 12 months (p < 0.05).
“A significant reduction was also identified in sedentary time using a computer, tablet or smartphone at home on non-workdays (p < 0.05) and while doing other sedentary leisure activities on workdays of 10 min/day and 22 min/day at the 6-(p < 0.05) and 12-month follow-ups (p < 0.05), respectively (see Table 6).”
Quote in the paperSubstantial claim - Premisecitation
Sedentary behaviour and physical inactivity are modifiable risk factors for the prevention, development and management of glucose intolerance and type 2 diabetes.
“Sedentary behaviour (SB) and physical inactivity -promoted by increasingly sedentary jobs [6]-have a high prevalence in adults with T2D [7,8] and are two of the main modifiable risk factors for the prevention, development and management of glucose intolerance (IGT or prediabetes) and T2D [9].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] Wilmot, 2012, Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis, Diabetologia source
- Interpretationreasoning
The delayed improvement in HbA1c may reflect a delayed metabolic response (lag effect) in which behavioural changes take time to consolidate and manifest physiologically.
“This pattern may reflect a delayed metabolic response (lag effect), in which behavioural changes initiated during the intervention take time to consolidate and manifest physiologically.”
Quote in the paperNot a substantial claim - Study design and conductown data
No statistically significant differences were found between the intervention and control groups at baseline in any measured variable.
“The homogeneity between the CG and IG was verified at the starting time that is, no statistically significant differences were found between both groups in any of the variables measured at baseline.”
- Also stated in: § 3.2. Baseline characteristics of the study participants · plain
“No statistically significant differences were observed between the intervention and control groups at the preliminary level in demographic characteristics and clinical variables.”
Quote in the paperSubstantial claim - Also stated in: § 3.2. Baseline characteristics of the study participants · plain
- Premisecitation
This study supports the results of studies of interventions based on mobile technology to promote physical activity, reduce and break sedentary behaviour in adults with type 2 diabetes that are effective.
“This study supports the results of studies of interventions based on mobile technology to promote physical activity, reduce and break SB in adults with T2D that are effective [33].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [33] Connelly, 2013, The use of technology to promote physical activity in Type 2 diabetes management: a systematic review, Diabet. Med. source
- Premisecitation
In adults with type 2 diabetes, the prevalence of sedentary behaviour and physical inactivity is related to a higher rate of cardiovascular morbidity and mortality.
“In adults with T2D, the prevalence of SB and physical inactivity is related to a higher rate of cardiovascular morbidity and mortality [9].”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [9] Wilmot, 2012, Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis, Diabetologia source
- Interpretationreasoning
Focusing the intervention on working hours, where a significant part of sedentary time accumulates, may have greater beneficial effects on type 2 diabetes and cardiovascular risk factor control.
“Another aspect related to the potential benefit of the mhealth programme is that the scope of the intervention was focused on working hours, where a significant part of sedentary time accumulates, potentially having greater beneficial effects in the control of T2D and CVR factors.”
Quote in the paperSubstantial claim- Rests on an assumption: Interventions in the workplace can be an effective health promotion strategy.
- Study design and conductown data
Other factors that might have influenced the results, such as changes in diet and medication during the intervention and follow-up period, were taken into account.
“Finally, other factors that might have influenced the results were taken into account, such as changes in diet and medication during the intervention and follow-up period.”
Quote in the paperSubstantial claim - Study design and conductreasoning
Data from patients who were recruited later had to be excluded because some of their follow-up periods coincided with the COVID-19 pandemic.
“Data from patients who were recruited later had to be excluded, as some of the follow-up periods coincided with the COVID-19 pandemic.”
Quote in the paperSubstantial claim - Interpretationown data
Despite the reduced sample size, the data generated are sufficient to indicate that the evaluated mHealth programme had an impact on the clinical variables and cardiovascular risk factors.
“Despite this, the data generated are sufficient to indicate that the evaluated mHealth programme had an impact on the clinical variables and cardiovascular risk factors.”
Quote in the paperSubstantial claim
- Classified as probably not a substantial claim. 12
- May combine two claims. 14
- The quote only partly states this claim. 1
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationSynchronizing the mobile application with a wearable device seems to be more effective than interventions without such a device.
“In addition, the patients synchronized the mobile application with a wearable device, which seems to be more effective [29,39] than interventions without such a device.”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [29] Cohen, 1988
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [39] Ashe, 2015, "Not just another walking program": everyday activity supports You (EASY) model-a randomized pilot study for a parallel randomized controlled trial, Pilot Feasibility Stud. source
The Intervention group and Control group sections describe a Fitbit-supported program versus education without a Fitbit; the Results report 2,080 more steps per day for the program at six months. But the program also included education, social support, and individualized activity guidance. The paper does not establish that synchronizing a mobile app with the wearable—or the wearable itself—made the intervention more effective. (LLM, conf=0.86)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationHelp and clinical support from professionals increase motivation, intervention adherence and potential clinical benefits in mHealth programmes for type 2 diabetes.
“Several recent studies of mHealth programmes for T2D have highlighted the importance of help and clinical support from professionals to increase motivation, intervention adherence and potential clinical benefits [42,43].”
Quote in the paperNot a substantial claim2 of 2 sources checked- cites [42] Lie, 2017, Dropout from an eHealth intervention for adults with type 2 diabetes: a qualitative study, J. Med. Internet Res. source
- cites [43] Cui, 2016, T2DM self-management via smartphone applications: a systematic review and meta-analysis, PLoS One source
The Results (Descriptions of Studies; page not provided) say the included mHealth studies used personalised feedback from healthcare practitioners. The Results (Study Outcomes) and Discussion report a significant HbA1c reduction for interventions with feedback, supporting potential clinical benefit. The paper does not establish that professional support increased patients’ motivation or intervention adherence. (LLM, conf=0.84)
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationIn adults with type 2 diabetes, interrupting sedentary time with short, regular, frequent episodes of light-intensity physical activity attenuates postprandial glucose, insulin, C-peptide and triglycerides, and reduces waist circumference, BMI and blood pressure.
“In adults with T2D, the interruption of sedentary time with short, regular and frequent episodes of light-intensity physical activity such as walking or simple resistance activities attenuates the level of postprandial glucose, insulin, C-peptide and triglycerides [45], and reduces waist circumference, body mass index (BMI) [46] and blood pressure [47].”
Quote in the paperSubstantial claim3 of 3 sources checked- cites [45] Loh, 2020, Effects of interrupting prolonged sitting with physical activity breaks on blood glucose, insulin and triacylglycerol measures: a systematic review and meta-analysis, Sports Med. source
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured - cites [46] Healy, 2015, Accelerometer-derived sedentary and physical activity time in overweight=obese adults with type 2 diabetes: cross-sectional associations with cardiometabolic biomarkers, PLoS One source
Split into 2 atoms — 0 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 1 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured - cites [47] Dempsey, 2018, Sitting less and moving more: Implications for hypertension, Hypertension source
The quote only partly states this claim.
Findingown dataIn office employees with type 2 diabetes, compared with usual care, the mHealth intervention produced a significant reduction in systolic blood pressure at 12 months (p < 0.05; about 8.82 mm Hg).
“Compared to the control group and at 12 months, the intervention group showed a significant reduction in HbA1c (p < 0.05), systolic and diastolic blood pressure (p < 0.05).”
- Also stated in: § 3.3. Study outcomes · plain
“In comparison with the control group, participants in the intervention group had significant and clinically relevant reductions in glycated hemoglobin (HbA1c; ≤-0.5 %, p < 0.01) and in SBP and DBP (p < 0.05) at the 12-month follow-up (see Table 4).”
- Also stated in: § 3.3. Study outcomes · plain
“The maximum difference between the groups for HbA1c and SBP was observed at the 12-month follow-up (0.50 % reduction in HbA1c concentration; 8.82 mm Hg reduction in SBP values).”
Quote in the paperSubstantial claim- Also stated in: § 3.3. Study outcomes · plain
May combine two claims.
Findingown dataIn office employees with type 2 diabetes, compared with usual care, the mHealth intervention did not significantly change total cholesterol, HDL cholesterol, LDL cholesterol, or triglycerides.
“No significant differences were found between groups regarding total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn office employees with type 2 diabetes, the differences in SBP and DBP between groups were greater at 6 months but remained significant at 12 months.
“The differences in SBP and DBP units between the groups were also greater at 6 months but remained significant at 12 months.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn office employees with type 2 diabetes, the differences in HbA1c percentage between intervention and control were minimal at 6 months but became clinically and statistically significant at 12 months.
“The differences in HbA1c percentage were minimal at 6 months, but they became clinically and statistically significant at the 12-month follow-up.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim.
Study design and conductown dataThe research team recording and monitoring clinical data was blinded to group allocation.
“The research team, in charge of recording and monitoring the clinical data, was blinded to the randomization of the patient group.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe person who performed the data analysis was not involved in data collection.
“In addition, the person who performed the data analysis was not involved in the data collection.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
PremisecitationmHealth programmes improve accessibility to health services, access to information, provide real-time information, and allow patients to monitor their own data.
“mHealth programmes improve accessibility to health services, improve access to information, provide patients with real-time information, and allow patients to monitor their own data [15].”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [15] Wang, 2014, Smartphone interventions for long-term health management of chronic diseases: an integrative review, Telemed. J. E Health source
Classified as probably not a substantial claim.
Study design and conductnone givenThe independent investigator who assessed participants at the end of the intervention and at follow-ups was blinded to group allocation.
“The independent investigator who assessed the participants at the end of the intervention and at follow-ups was blinded to the participants' group allocation.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataThe mHealth programme is an effective lifestyle intervention for reducing sedentary behaviour and improving HbA1c and blood pressure in adults with type 2 diabetes.
“An mHealth programme effectively reduced sedentary behaviour, improved HbA1c and blood pressure, serving as a cost-effective lifestyle intervention for adults with T2D.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataThe study was a parallel, single-blind randomized controlled trial with 1:1 allocation of 54 eligible adults with type 2 diabetes.
“This study is a parallel, single-blind, randomized controlled trial (RCT) that enrolled 54 eligible adults with T2D with a 1:1 allocation.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe RCT was registered at ClinicalTrials.gov (NCT04092738) and written in accordance with the CONSORT-EHEALTH checklist.
“This RCT was registered at ClinicalTrials.gov(identification number: NCT04092738) and has been written in accordance with the new CONSORT-EHEALTH checklist (Multimedia Appendix 1 CONSORT-EHEALTH V1.6).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductown dataThe study was approved by the Clinical Research Ethics Committee of the Primary Care Research Institute Jordi Gol (P18/102) and all participants provided written informed consent.
“This study was approved by the Clinical Research Ethics Committee of the Primary Care Research Institute Jordi Gol with the registration code P18/102.All participants provided written informed consent prior to participation.”
Quote in the paperNot a substantial claimClassified as probably not a substantial claim. May combine two claims.
Study design and conductown dataRandomization was performed in a 1:1 ratio using a computerized random number generator.
“Randomization was performed in a 1:1 ratio using a computerized random number generator.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown data82% of intervention participants used the mHealth programme for at least 50% of days during the ramping phase.
“82 % of participants (n = 24) in the intervention group used the mhealth programme for at least 50 % of days during the ramping phase (Fig. 1).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing), S4 (based).
Interpretationnone givenThe sustainability of the intervention effect at 12 months could be explained by the 3-month duration of the intervention.
“One factor that could explain the sustainability of the effect of the intervention at 12 months could be the 3-month duration of the intervention.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
InterpretationreasoningThrough the use of tracking devices and continuous feedback, participants became aware of their physical activity and behavioural patterns, allowing them to visualize and measure their achievements, thus increasing motivation to continue making changes to reach their goals.
“Through the use of tracking devices and continuous feedback, participants became aware of their physical activity and behavioural patterns, allowing them to visualize and measure their achievements, thus increasing motivation to continue making changes to reach their goals.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductreasoningThe statistical power of the study is lower than initially desirable, so interpretation of the results requires caution.
“The statistical power is lower than initially desirable, so we need to be cautious in the interpretation of the results.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductnone givenThe funders had no role in the design, analysis, data interpretation or writing of the manuscript.
“The funders had no role in the design, analysis, data interpretation or writing of the manuscript.”
Quote in the paperNot a substantial claimMay combine two claims.
Study design and conductreasoningThe main limitation of the study was the sample size, because patient recruitment had to be completely suspended due to the COVID-19 pandemic, leading to a reduction in the total sample.
“The main limitation was the sample size, as patient recruitment had to be completely suspended due to the COVID-19 pandemic, owing to legal restrictions, logistical issues, and operational problems related to the pandemic.This led to a reduction in the total sample of patients.”
Quote in the paperSubstantial claim
The paper relies on this without support.
The short-, medium-, and long-term impact of mHealth programmes in modifying the sedentary behaviour pattern in the clinical population is unclear.
“In this regard, the short-, medium-, and long-term impact of mHealth programmes in modifying the SB pattern in the clinical population is unclear.”
The paper relies on this without support.
Few studies measure the impact of mHealth interventions on promoting physical activity and reducing sedentary behaviour and HbA1c levels compared to usual care in patients with type 2 diabetes in primary care.
“There are few studies that measure the impact of mhealth interventions on promoting physical activity and reducing SB and HbA1c levels compared to usual care in patients with T2D in primary care.”
The paper relies on this without support.
Few mobile applications include changing the sedentary behaviour pattern as the main intervention strategy in the self-management of type 2 diabetes.
“Few include changing the SB pattern as the main intervention strategy in the self-management of the disease.”
The paper relies on this without support.
Interventions in the workplace can be an effective health promotion strategy.
“Interventions in the workplace can be an effective health promotion strategy, which has also been endorsed by the World Health Organization.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Over time, repeated goal attainment and visible progress may strengthen patients' sense of mastery and self-efficacy, thereby facilitating a shift from externally prompted behavior to proactive self-management.
“Over time, repeated goal attainment and visible progress may strengthen patients' sense of mastery and self-efficacy, thereby facilitating a shift from externally prompted behavior to proactive self-management (14, 17, 20, 25, 26).”
From Behavior change pathways by which digital wearable devices support exercise self-management in type 2 diabetes: a scoping review with machine learning–assisted text mining (2026) · cites this paper as [25]
The discussion (section 4.2; page unavailable) says that tracking and feedback let participants visualize their achievements, increasing motivation to keep working toward their goals. The intervention description (section 2.6; page unavailable) also documents goal-setting and progress feedback. The paper does not say that repeated attainment strengthens mastery or self-efficacy, or that patients shift from external prompts to proactive self-management. (LLM, conf=0.84)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
Eligibility counts differ between Methods and Results
MajorThe Methods say 75 patients were invited, whereas the Results say 70 were assessed for eligibility. They also give different exclusion counts: 21 versus 10.
“In March 2019, three primary health care centres participated simultaneously, inviting a total of 75 patients.54 agreed to participate and 21 were excluded”
“A total of 70 participants were assessed for eligibility, of which 10 were excluded (8 did not meet the inclusion criteria and 2 declined to participate).”
Cholesterol and triglyceride findings contradict the stated nonsignificant results
MajorThe narrative says neither measure differed significantly between groups, but Table 4 reports p = 0.00110 for the 12-month total-cholesterol change and p = 0.0184 for the 12-month triglyceride change.
“No significant differences were found between groups regarding total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides.”
“| Difference (t = 0and t = | -26.37 | 8.68 | 0.00110 |”
Reported overall age is below both group means
MinorThe stated overall mean age of 54.498 years cannot be the mean of groups whose reported mean ages are 55.62 and 55.37 years.
“The mean age of the participants was 54.498 (SD 7.24) years”
“Age (years), mean (SD) 55.62 (6.93) 55.37 (7.56)”
Number randomized differs between Methods and Results
MinorThe Methods describe 54 patients as randomly assigned, but the Results describe 60 as randomly assigned and 54 as completing follow-up.
“29 and 25 patients were randomly assigned to the intervention (mHealth programme) and control (usual care) groups, respectively.”
“60 individuals were eligible and were randomly assigned.In the intervention group (n = 30), one participant (3 %) declined to participate, and 29 participants (96 %) completed the trial.In the control group (n = 30), 25 participants (83 %) completed the follow-up.”
Table 1 states an incompatible total sample size
MinorTable 1 labels its baseline sample as 99, although its group headings contain 25 and 29 participants, totaling 54.
“Baseline sociodemographic characteristics and clinical outcomes of the study participants (n = 99).Homogeneity of the groups at baseline.”
“Control (n ¼ 25) Intervention (n ¼ 29)”
Three-month measurement counts disagree
MinorThe Results assign the 16 three-month measurements to nine control and seven intervention patients; Table 5 instead labels the groups as ten control and six intervention patients.
“Sixteen measurements were obtained (9 patients from the control group and 7 from the intervention group) during the 3month follow-up”
“| | (n ¼ 10) | (n ¼ 6) | |”
Control-group sedentary-break categories exceed their reported total
MinorTable 2 reports 49.97 total sedentary breaks per day in controls, but its four mutually exclusive break-duration categories sum to 50.80 per day.
Reported 49.97 · recomputed 50.8
“| Total sedentary breaks (number/ | 49.97 (16.95) | 44.81 (12.99) | 0.1478 |”
Claimed 12-month workplace-sitting change is not significant in Table 6
MinorThe Results claim a significant between-group reduction at 12 months, but Table 6 reports p = 0.2296 for the corresponding baseline-to-12-month change.
“Sitting time while at work of 45.63 min/day and 26.25 min/day at the 6-(p < 0.01) and 12-month follow-ups (p < 0.05), respectively.”
“Difference (t = 0and t = 12) -11.00 (95.68) -26.25 (51.90) 0.2296”
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Flagged first, then by citations
Research works printed but not linked: 1
- Holmen, 2014, A mobile health intervention for self-management and lifestyle change for persons with type 2 diabetes, part 2: one-year results from the norwegian randomized controlled trial RENEWING HEALTH, JMIR mhealth uhealth, 2, 10.2196/mhealth.3882 · DOI · Paper page
Cited by
Sorted by citations
Sun, W., Xie, D., Hou, W., Zhang, M., Wang, C., Wang, Z., Yang, H., Xu, G., & Dai, H. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1871682
- Authors
- Alòs, F., Colomer, M. À., Bort-Roig, J., Martin-Cantera, C., Minaya, A., Saigí, I., Sitjar-Suñer, M., & Puig-Ribera, A.
- Affiliations
- Institut Universitari d'Investigació en Atenció Primària Jordi Gol (ES)
- Universitat de Lleida (ES)
- Hospital Universitari de Vic (ES)
- Universitat de Girona (ES)
- Universitat de Vic - Universitat Central de Catalunya (ES)
- Corresponding author
- Puig-Ribera, Anna
- Venue
- Primary Care Diabetes
- Publisher
- Elsevier BV
- Published
- 2025-10
- Volume
- 19
- Issue
- 5
- Pages
- 434-445
- ISSN
- 1751-9918 (ISSN-L)
- OpenAlex
- W4411155647
- Semantic Scholar
- 8fe9fb3c0feab6098fe71837731ce925e6d87dc3
- Cited by
- 11
- References
- 44
- Citations by year
- 2026: 10 · 2025: 1
- FWCI
- 13.32
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Primary care diabetes (publishedVersion, cc-by)
- PubMed (publishedVersion)
- RIUVic (UVic-UCC) (submittedVersion, cc-by)
- Repositori ObertUDL (University of Lleida) (submittedVersion, cc-by)
- Funders
- European Regional Development Fund (redgdps/BJLTB/02/2022)
- Universitat Autònoma de Barcelona
- Sociedad Española de Medicina de Familia y Comunitaria
- Carlos III Health Institute (PI17/01788)
- Topics
- Health Sciences › Health Professions › General Health Professions › Mobile Health and mHealth Applications
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Keywords
- type 2 diabetes, mobile health, sedentary behavior, physical activity, office workers, HbA1c, blood pressure, lifestyle intervention, workplace health promotion, primary care, sedentary breaks, sedentary bouts
- MeSH terms
- Healthy Lifestyle, Sitting Position, Adult, Aged, Blood Glucose, Blood Pressure, Diabetes Mellitus, Type 2, Female, Glycated Hemoglobin, Humans, Male, Middle Aged, Primary Health Care, Time Factors, Biomarkers, Exercise, Occupational Health, Treatment Outcome, Telemedicine, Risk Reduction Behavior, Sedentary Behavior, Mobile Applications
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