Bulimia nervosa and evidence for striatal dopamine dysregulation: A conceptual review
Open accessAbstract
Objective This article reviews concepts and evidence, based in particular on the work of Bartley G. Hoebel and colleagues, which suggest that a better understanding of the role of striatal dopamine (DA) in the initiation and/or maintenance of bulimia nervosa (BN) may result in a clearer characterization of mechanisms underlying BN.Methods Literature review, using PubMed search.Results Several lines of evidence, including the work of Bartley G. Hoebel, implicate the importance of striatal DA in feeding behavior, as well as in the disordered eating behaviors relevant to BN. Preclinical models of 'BN-like' eating behaviors have been associated with changes in striatal DA and DA receptor measures. Emerging clinical research also suggests that striatal DA abnormalities exist in individuals with BN.Conclusion Alterations in striatal DA may exist in patients with BN. While the precise relationship between these findings and the etiology and maintenance of bulimic symptomatology remains unclear, further investigation of brain DA systems is a fruitful avenue of future research in BN.
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Early hallmark preclinical studies by Hoebel and colleagues highlighted commonalities between BN and addiction disorders in terms of neurobiology, psychopharmacology, neurochemistry, and behavior.
“Indeed, early hallmark preclinical studies by Hoebel and colleagues [318] highlighted commonalities between BN and addiction disorders in terms of neurobiology, psychopharmacology, neurochemistry, and behavior [319].”
From Reward circuitry dysfunction in psychiatric and neurodevelopmental disorders and genetic syndromes: animal models and clinical findings (2012) · cites this paper as [319]
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Cites
The prevalence and correlates of eating disorders in the National Comorbidity Survey Replication
Hudson, J. I., Hiripi, E., Pope, H. G., & Kessler, R. C. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.03.040 · Cited by 4,973 · see citing works
Binge eating as escape from self-awareness
Heatherton, T. F., & Baumeister, R. F. (1991) · Psychological Bulletin · doi:10.1037/0033-2909.110.1.86 · Cited by 2,259 · see citing works
THE BIOLOGY OF HUMAN STARVATION
Keys, A., BROŽEK, J., & Henschel, A. (1951) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1951.tb56499.x · Cited by 2,053 · see citing works
Wang, G.-J., Volkow, N. D., Logan, J., Pappas, N. R., Wong, C. T., Zhu, W., Netusll, N., & Fowler, J. S. (2001) · The Lancet · doi:10.1016/s0140-6736(00)03643-6 · Cited by 1,864 · see citing works
Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
Johnson, P. M., & Kenny, P. J. (2010) · Nature Neuroscience · doi:10.1038/nn.2519 · Cited by 1,495 · see citing works
Fairburn, C. G., & Harrison, P. J. (2003) · The Lancet · doi:10.1016/s0140-6736(03)12378-1 · Cited by 1,396 · see citing works
Avena, N. M., Rada, P., & Hoebel, B. G. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.04.019 · Cited by 1,358 · see citing works
Putting a spin on the dorsal-ventral divide of the striatum
Voorn, P., Vanderschuren, L. J. M. J., Groenewegen, H. J., Robbins, T. W., & Pennartz, C. M. A. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.06.006 · Cited by 1,188 · see citing works
Imaging dopamine's role in drug abuse and addiction
Volkow, N. D., Fowler, J. S., Wang, G. J., Baler, R., & Telang, F. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.05.022 · Cited by 988 · see citing works
Kendler, K. S. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950170048007 · Cited by 693 · see citing works
Daily bingeing on sugar repeatedly releases dopamine in the accumbens shell
Rada, P. V., Avena, N. M., & Hoebel, B. G. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.043 · Cited by 542 · see citing works
Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain
Colantuoni, C., Schwenker, J., McCarthy, J., Rada, P., Ladenheim, B., Cadet, J.-L., Schwartz, G. J., Moran, T. H., & Hoebel, B. G. (2001) · Neuroreport · doi:10.1097/00001756-200111160-00035 · Cited by 471 · see citing works
Oral sucrose stimulation increases accumbens dopamine in the rat
Hajnal, A., Smith, G. P., & Norgren, R. (2004) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00282.2003 · Cited by 449 · see citing works
Cognitive Behavioral Therapy for Eating Disorders
Murphy, R., Straebler, S., Cooper, Z., & Fairburn, C. G. (2010) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2010.04.004 · Cited by 435 · see citing works
Martinez, D., Narendran, R., Foltin, R. W., Slifstein, M., Hwang, D.-R., Broft, A., Huang, Y., Cooper, T. B., Fischman, M. W., Kleber, H. D., et al. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.4.622 · Cited by 351 · see citing works
Self-citationBook Review: Reward Signaling by Dopamine Neurons
Schultz, W. (2001) · The Neuroscientist · doi:10.1177/107385840100700406 · Cited by 343 · see citing works
A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine
Avena, N. M., & Hoebel, B. G. (2003) · Neuroscience · doi:10.1016/s0306-4522(03)00502-5 · Cited by 284 · see citing works
Opiate-like effects of sugar on gene expression in reward areas of the rat brain
Spangler, R., Wittkowski, K. M., Goddard, N. L., Avena, N. M., Hoebel, B. G., & LEIBOWITZ, S. F. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.02.013 · Cited by 255 · see citing works
Pothos, E. N., Creese, I., & Hoebel, B. G. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-10-06640.1995 · Cited by 225 · see citing works
The Neurobiology of Addiction: Implications for Voluntary Control of Behavior
Hyman, S. E. (2007) · The American Journal of Bioethics · doi:10.1080/15265160601063969 · Cited by 223 · see citing works
HOEBEL, B. G., HERNANDEZ, L., SCHWARTZ, D. H., MARK, G. P., & HUNTER, G. A. (1989) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1989.tb53242.x · Cited by 220 · see citing works
A Neural Signature of Anorexia Nervosa in the Ventral Striatal Reward System
Fladung, A.-K., Grön, G., Grammer, K., Herrnberger, B., Schilly, E., Grasteit, S., Wolf, R. C., Walter, H., & von Wietersheim, J. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2009.09010071 · Cited by 220 · see citing works
Jimerson, D. C. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820020052007 · Cited by 219 · see citing works
Yanovski, S. Z. (2003) · International Journal of Eating Disorders · doi:10.1002/eat.10211 · Cited by 196 · see citing works
Avena, N. M., Rada, P. V., Moise, N., & Hoebel, B. G. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2005.12.037 · Cited by 195 · see citing works
Deficient Activity in the Neural Systems That Mediate Self-regulatory Control in Bulimia Nervosa
Marsh, R., Steinglass, J. E., Gerber, A. J., Graziano O’Leary, K., Wang, Z., Murphy, D., Walsh, B. T., & Peterson, B. S. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.504 · Cited by 190 · see citing works
Self-citationThe Treatment of Eating Disorders: A Clinical Handbook
Mickley, D. W. (2010) · Eating Disorders · doi:10.1080/10640266.2010.490128 · Cited by 188 · see citing works
Dopamine and binge eating behaviors
Bello, N. T., & Hajnal, A. S. (2010) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2010.04.016 · Cited by 177 · see citing works
Overeating, Binge Eating, and Eating Disorders as Addictions
Gold, M. S., Frost-Pineda, K., & Jacobs, W. S. (2003) · Psychiatric Annals · doi:10.3928/0048-5713-20030201-08 · Cited by 162 · see citing works
Sensitization Processes in Drug Addiction
Vanderschuren, L. J. M. J., & Pierce, R. C. (2009) · Current topics in behavioral neurosciences · doi:10.1007/7854_2009_21 · Cited by 161 · see citing works
A naturalistic investigation of eating behavior in bulimia nervosa.
Davis, R., Freeman, R. J., & Garner, D. M. (1988) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.56.2.273 · Cited by 155 · see citing works
Repeated sucrose access influences dopamine D2 receptor density in the striatum
Bello, N. T., Lucas, L. R., & Hajnal, A. (2002) · Neuroreport · doi:10.1097/00001756-200208270-00017 · Cited by 144 · see citing works
Thanos, P. K., Michaelides, M., Piyis, Y. K., Wang, G., & Volkow, N. D. (2008) · Synapse · doi:10.1002/syn.20468 · Cited by 135 · see citing works
Tauscher, J., Pirker, W., Willeit, M., de Zwaan, M., Bailer, U., Neumeister, A., Asenbaum, S., Lennkh, C., Praschak-Rieder, N., Brücke, T., et al. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)00951-3 · Cited by 134 · see citing works
A naturalistic investigation of eating behavior in bulimia nervosa.
Davis, R., Freeman, R. J., & Garner, D. M. (1988) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.56.2.273 · Cited by 120 · see citing works
Lee, S., Lee, A. M., Leung, T. Y. S., & Yu, H. H. (1997) · International Journal of Eating Disorders · doi:10.1002/(sici)1098-108x(199703)21:2 · Cited by 117 · see citing works
Bello, N. T., Sweigart, K. L., Lakoski, J. M., Norgren, R., & Hajnal, A. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00716.2002 · Cited by 112 · see citing works
Butryn, M. L., Lowe, M. R., Safer, D. L., & Agras, W. S. (2006) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.115.1.62 · Cited by 109 · see citing works
Examining the addictive-like properties of binge eating using an animal model of sugar dependence.
Avena, N. M. (2007) · Experimental and Clinical Psychopharmacology · doi:10.1037/1064-1297.15.5.481 · Cited by 105 · see citing works
Repeated access to sucrose augments dopamine turnover in the nucleus accumbens
Hajnal, A. S., & Norgren, R. (2002) · Neuroreport · doi:10.1097/00001756-200212030-00010 · Cited by 100 · see citing works
Cadoni, C., Solinas, M., Valentini, V., & Chiara, G. D. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02941.x · Cited by 97 · see citing works
Altered striatal response to reward in bulimia nervosa after recovery
Wagner, A., Aizenstein, H., Venkatraman, V. K., Bischoff‐Grethe, A., Fudge, J., May, J. C., Frank, G. K., Bailer, U. F., Fischer, L., Putnam, K., et al. (2010) · International Journal of Eating Disorders · doi:10.1002/eat.20699 · Cited by 93 · see citing works
Corwin, R. L., & Wojnicki, F. H. E. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3283313168 · Cited by 78 · see citing works
Bulimia Nervosa and Substance Dependence: Association and Family Transmission
Kaye, W. H., Lilenfeld, L., Plotnicov, K. H., Merikangas, K. R., Nagy, L. M., Strober, M., Bulik, C. M., Moss, H. B., & Greeno, C. G. (1996) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb05266.x · Cited by 72 · see citing works
Weight suppression predicts weight gain during inpatient treatment of bulimia nervosa
Lowe, M. R., Davis, W., Lucks, D. L., Annunziato, R. A., & Butryn, M. L. (2006) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.11.011 · Cited by 72 · see citing works
Pothos, E. N., Hernandez, L., & Hoebel, B. G. (1995) · Obesity Research · doi:10.1002/j.1550-8528.1995.tb00222.x · Cited by 70 · see citing works
Amenorrhea in anorexia nervosa neuroendocrine control of hypothalamic dysfunction
Golden, N. H., & Shenker, I. R. (1994) · International Journal of Eating Disorders · doi:10.1002/1098-108x(199407)16:1 · Cited by 57 · see citing works
The treatment of eating disorders: a clinical handbook.
Grilo, C. M., & Mitchell, J. E. (2010) · Cited by 56 · see citing works
Cracking the moody brain: The rewards of self starvation
Zink, C. F., & Weinberger, D. R. (2010) · Nature Medicine · doi:10.1038/nm1210-1382 · Cited by 52 · see citing works
Thanos, P. K., Michaelides, M., Ho, C. W., Wang, G., Newman, A. H., Heidbreder, C. A., Ashby, C. R., Gardner, E. L., & Volkow, N. D. (2008) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2008.02.003 · Cited by 47 · see citing works
Endorphins, Eating Disorders, and Other Addictive Behaviors
Huebner, H. F. (1993) · Medical Entomology and Zoology · Cited by 41 · see citing works
Perplexities and provocations of eating disorders
Halmi, K. A. (2009) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.2008.01983.x · Cited by 37 · see citing works
Bulimic Vomiting Alters Pain Tolerance and Mood
Abraham, H. D., & Joseph, A. B. (1987) · The International Journal of Psychiatry in Medicine · doi:10.2190/qg04-42ku-mkvr-crht · Cited by 28 · see citing works
Diagnosis, assessment, and treatment planning for bulimia nervosa.
Crow, S. J., Brandenburg, B., Grilo, C. M., & Mitchell, J. E. (2010) · Cited by 14 · see citing works
McAleavey, K., & Fiumara, M. C. (2001) · Journal of Social Work Practice in the Addictions · doi:10.1300/j160v01n02_09 · Cited by 6 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- [2]American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition - Text Revision 2000 Washington DC American Psychiatric Association
Cited by
Sorted by citations
Sex differences in the physiology of eating
Asarian, L., & Geary, N. (2013) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00446.2012 · Cited by 513 · see citing works
Dichter, G. S., Damiano, C. A., & Allen, J. A. (2012) · Journal of Neurodevelopmental Disorders · doi:10.1186/1866-1955-4-19 · Cited by 299 · see citing works
A meta-analysis of cytokine concentrations in eating disorders
Dalton, B., Bartholdy, S., Robinson, L., Solmi, M., Ibrahim, M. A. A., Breen, G., Schmidt, U., & Himmerich, H. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.06.002 · Cited by 197 · see citing works
Piccoli, L., Bonaventura, M. V. M. D., Cifani, C., Costantini, V. J. A., Massagrande, M., Montanari, D., Martinelli, P., Antolini, M., Ciccocioppo, R., Massi, M., et al. (2012) · Neuropsychopharmacology · doi:10.1038/npp.2012.48 · Cited by 154 · see citing works
Food addiction and body-mass-index: A non-linear relationship
Meule, A. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2012.07.005 · Cited by 83 · see citing works
A literature review of dopamine in binge eating
Yu, Y. H., Miller, R. M., & Groth, S. W. (2022) · Journal of Eating Disorders · doi:10.1186/s40337-022-00531-y · Cited by 85 · see citing works
Carlin, J. L., McKee, S. E., Hill‐Smith, T. E., Grissom, N. M., George, R., Lucki, I., & Reyes, T. M. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.04.002 · Cited by 63 · see citing works
Jiang, T., Soussignan, R., Carrier, E., & Royet, J. (2019) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2019.00117 · Cited by 57 · see citing works
Bello, N. T., Coughlin, J. W., Redgrave, G. W., Ladenheim, E. E., Moran, T. H., & Guarda, Á. S. (2011) · Physiology & Behavior · doi:10.1016/j.physbeh.2011.09.021 · Cited by 40 · see citing works
Addicted to palatable foods: comparing the neurobiology of Bulimia Nervosa to that of drug addiction
Hadad, N. A., & Knackstedt, L. A. (2014) · Psychopharmacology · doi:10.1007/s00213-014-3461-1 · Cited by 39 · see citing works
Bonaventura, M. V. M. D., Pucci, M., Giusepponi, M. E., Romano, A., Lambertucci, C., Volpini, R., Bonaventura, E. M. D., Gaetani, S., Maccarrone, M., D’Addario, C., et al. (2019) · Journal of Psychopharmacology · doi:10.1177/0269881119845798 · Cited by 26 · see citing works
Subcortical Shape Abnormalities in Bulimia Nervosa
Berner, L. A., Wang, Z., Stefan, M., Lee, S., Huo, Z., Cyr, M., & Marsh, R. (2019) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2018.12.011 · Cited by 25 · see citing works
Self-citationMeule, A., & Kübler, A. (2012) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2012.00064 · Cited by 23 · see citing works
Guerdjikova, A. I., & McElroy, S. L. (2013) · Europe PMC (PubMed Central) · Cited by 23 · see citing works
González, L. M., Mota-Zamorano, S., García‐Herráiz, A., López-Nevado, E., & Gervasini, G. (2019) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-019-00820-7 · Cited by 20 · see citing works
Dougherty, E. N., Bottera, A. R., Forester, G., Schaefer, L. M., Forbes, E. E., & Wildes, J. E. (2024) · Psychiatry Research · doi:10.1016/j.psychres.2024.115717 · Cited by 18 · see citing works
Theory construction in the psychopathology domain: A multiphase approach
Hawkins-Elder, H., & Ward, T. J. (2019) · Theory & Psychology · doi:10.1177/0959354319893026 · Cited by 14 · see citing works
CCK response in bulimia nervosa and following remission
Hannon-Engel, S. L., Filin, E. E., & Wolfe, B. E. (2013) · Physiology & Behavior · doi:10.1016/j.physbeh.2013.08.014 · Cited by 13 · see citing works
Pascale, E., Cimino, S., Cerniglia, L., & Bevilacqua, A. (2022) · Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity · doi:10.1007/s40519-022-01408-4 · Cited by 7 · see citing works
The Explanation of Eating Disorders: A Critical Analysis
Hawkins-Elder, H., & Ward, T. J. (2020) · Behaviour Change · doi:10.1017/bec.2020.6 · Cited by 7 · see citing works
Anorexia Nervosa and Bulimia Nervosa
Crow, S. J., & Eckert, E. D. (2016) · Springer eBooks · doi:10.1007/978-1-4939-2528-5_12 · Cited by 6 · see citing works
Disordered Social Cognition: Alexithymia and Interoception
Brewer, R., & Bird, G. (2020) · The Cambridge Handbook of Evolutionary Perspectives on Human Behavior · doi:10.1017/9781108131797.036 · Cited by 3 · see citing works
Bulimia Nervosa as an Addiction
Hadad, N. A., & Knackstedt, L. A. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800634-4.00100-1 · Cited by 1 · see citing works
Dönmez, R. B., Demirel, T. N., Bilgin, C., Tarhan, N., Örkçü, Ö., Ceylan, Z., & Güleken, Z. (2023) · Addiction and Health · doi:10.34172/ahj.2023.1466 · Cited by 1 · see citing works
Recovery from Bulimia: What Helps in Healing
Reynen, E. (2012) · UST Research Online (University of St. Thomas - Minnesota)
Björnsdóttir, H. H. (2013)
Diagnosis and treatment of bulimia
Zorić, A. B. (2017)
Neurobiology of Eating Disorders and the Use of Psychotropic Medications
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Imaging of feeding and eating disorders
Kurniadi, N. E., Wierenga, C. E., Berner, L. A., & Kaye, W. H. (2020) · doi:10.1093/med/9780198713005.003.0105
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Hawkins-Elder, H. (2021) · doi:10.26686/wgtn.16895614.v1 · Cited by 3 · see citing works
Steiger, H., Booij, L., St‐Hilaire, A., & Thaler, L. (2023) · Oxford University Press eBooks · doi:10.1093/med-psych/9780197542521.003.0018
Yates, J. R. (2026) · Springer eBooks · doi:10.1007/978-3-032-15602-0_13
A neurodevelopmental model of eating disorder risk in midlife to older adulthood
Heintz, H., Haynos, A. F., Hagan, K. E., & Berner, L. A. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106830
Self-citation
- Authors
- Broft, A. I., Berner, L. A., Martinez, D., & Walsh, B. T.
- Affiliations
- New York State Psychiatric Institute (US)
- Corresponding author
- Broft, Allegra I.
- Venue
- Physiology & Behavior
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 104
- Issue
- 1
- Pages
- 122-127
- ISSN
- 0031-9384 (ISSN-L)
- PMC
- PMC3111921
- OpenAlex
- W1968873029
- Cited by
- 34
- References
- 54
- Citations by year
- 2026: 2 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 3 · 2019: 5 · 2018: 2 · 2017: 1 · 2016: 3 · 2014: 1 · 2013: 4 · 2012: 5
- FWCI
- 3.80
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Physiology & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R21MH65024, T32MH15144, R21MH065024, K23MH082097, T32MH015144)
- National Center for Research Resources (KL2RR024157)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- bulimia nervosa, striatal dopamine, dopamine dysregulation, feeding behavior, disordered eating, dopamine receptors, preclinical animal models, brain circuits
- MeSH terms
- Corpus Striatum, Dopamine, Feeding Behavior, Humans, Neurons, Bulimia Nervosa
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