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Cited by 287

The DOI matches its Crossref record; 18 of the 18 references it cites were found in a registry or an index.

Long-Term Consequences: Effects on Normal Development Profile After Concussion

Open access
Daneshvar, Daniel H., Riley, David O., Nowinski, Christopher J., McKee, Ann C., Stern, Robert A., Cantu, Robert C.·2011·Physical Medicine and Rehabilitation Clinics of North America
DOI 10.1016/j.pmr.2011.08.009
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Abstract

Each year in the United States, approximately 1.7 million people are diagnosed with a traumatic brain injury (TBI); an estimated 75% of these injuries are classified as mild TBIs (mTBI) or concussions. The symptoms of such injuries include a variety of somatic, cognitive, and behavioral deficits. While these symptoms typically resolve in a matter of weeks, both children and adults may suffer from Post-Concussion Syndrome (PCS) for months or longer. Suffering from PCS-related symptoms for an extended time may delay an individual’s return to work, adversely affect one’s quality of life, and result in additional social and economic costs. Though a consensus has not been reached on the cause of long-term PCS, it is likely that biological, physiological, psychological, and social elements all play a role in symptom persistence. Additionally, persistent PCS may adversely affect one’s developmental trajectory. The enduring effects of head trauma are not limited to PCS-related effects, however. A progressive tauopathy, chronic traumatic encephalopathy (CTE) is believed to stem from repeated brain trauma. While CTE was originally associated with boxing, it has recently been found in other cases of repetitive head injury including former football and hockey players, and professional wrestlers. In addition to this observed pathology, repetitive brain trauma is also associated with Alzheimer’s-like dementia, Parkinsonism, and motor neuron disease including Amyotrophic Lateral Sclerosis (ALS). With these significant long-term effects of head injuries, there is a clear need to develop effective diagnoses, treatments, and education plans to reduce future burden and incidence.

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Crossref · 10.1016/j.pmr.2011.08.009

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Metadata

Authors
Daneshvar, D. H., Riley, D. O., Nowinski, C. J., McKee, A. C., Stern, R. A., & Cantu, R. C.
Venue
Physical Medicine and Rehabilitation Clinics of North America
Publisher
Elsevier BV
Published
2011-11
Volume
22
Issue
4
Pages
683-700
ISSN
1047-9651 (ISSN-L)
DOI
10.1016/j.pmr.2011.08.009
OpenAlex
W1967164782
Cited by
287
References
18
FWCI
7.78
Type
journal article
Language
en
Open access
green

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