Genetics of obsessive-compulsive disorder
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Obsessive-compulsive disorder is a common debilitating condition affecting individuals from childhood through adult life. There is good evidence of genetic contribution to its etiology, but environmental risk factors also are likely to be involved. The condition probably has a complex pattern of inheritance. Molecular studies have identified several potentially relevant genes, but much additional research is needed to establish definitive causes of the condition.
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The risk of OCD is significantly higher for relatives of patients.
“The risk of OCD is significantly higher for relatives of patients (Gottesman and Gould, 2003, Nestadt et al., 2010, Pauls, 2008, Pauls et al., 2014).”
From Imbalance between the caudate and putamen connectivity in obsessive–compulsive disorder (2022) · cites this paper as Nestadt et al., 2010
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Insensitivity to future consequences following damage to human prefrontal cortex
Bechara, A., Damasio, A. R., Damasio, H., & Anderson, S. W. (1994) · Cognition · doi:10.1016/0010-0277(94)90018-3 · Cited by 6,128 · see citing works
Higgins, S. M. F., Macken, A. P., Cullen, W., Saunders, J., Dunne, C. P., & O’Gorman, C. S. (2013) · PubMed · doi:10.34961/9953 · Cited by 4,806 · see citing works
Complement factor H polymorphism in age-related macular degeneration
Klein, R. J., Zeiss, C., Chew, E. Y., Tsai, J.-Y., Sackler, R. S., Haynes, C., Henning, A. K., SanGiovanni, J. P., Mane, S. M., Mayne, S. T., et al. (2005) · Science · doi:10.1126/science.1109557 · Cited by 4,492 · see citing works
Merlin—rapid analysis of dense genetic maps using sparse gene flow trees
Abecasis, G. R., Cherny, S. S., Cookson, W., & Cardon, L. R. (2001) · Nature Genetics · doi:10.1038/ng786 · Cited by 3,323 · see citing works
Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21
Hall, J., Lee, M. K., Newman, B. M., Morrow, J. E., Anderson, L. A., Huey, B., & King, M. (1990) · Science · doi:10.1126/science.2270482 · Cited by 2,544 · see citing works
Psychiatric disorders in America
Robins, L. N. (1991) · Medical Entomology and Zoology · Cited by 1,567 · see citing works
Botstein, D., & Risch, N. (2003) · Nature Genetics · doi:10.1038/ng1090 · Cited by 1,503 · see citing works
Hu, X., Lipsky, R. H., Zhu, G., Akhtar, L. A., Taubman, J., Greenberg, B. D., Xu, K., Arnold, P. D., Richter, M. A., Kennedy, J. L., et al. (2006) · The American Journal of Human Genetics · doi:10.1086/503850 · Cited by 1,124 · see citing works
A multidimensional model of obsessive-compulsive disorder
Mataix-Cols, D., do Rosario-Campos, M. C., & Leckman, J. F. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.2.228 · Cited by 1,074 · see citing works
Allele-sharing models: LOD scores and accurate linkage tests.
Kong, A., & Cox, N. (1997) · American Journal of Human Genetics · doi:10.1086/301592 · Cited by 1,036 · see citing works
A family study of obsessive–compulsive disorder
(1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.1.76 · Cited by 1,022 · see citing works
Abramowitz, J. S., Taylor, S., & McKay, D. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60240-3 · Cited by 1,002 · see citing works
Mataix-Cols, D., Wooderson, S., Lawrence, N., Brammer, M. J., Speckens, A., & Phillips, M. L. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.6.564 · Cited by 929 · see citing works
The Epidemiology and Clinical Features of Obsessive Compulsive Disorder
Rasmussen, S. A., & Eisen, J. L. (1992) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30205-3 · Cited by 874 · see citing works
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice
Welch, J. M., Lu, J., Rodriguiz, R. M., Trotta, N. C., Peca, J., Ding, J.-D., Feliciano, C., Chen, M., Adams, J. P., Luo, J., et al. (2007) · Nature · doi:10.1038/nature06104 · Cited by 852 · see citing works
Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder
Saxena, S., & Rauch, S. L. (2000) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70181-7 · Cited by 840 · see citing works
Neuroimaging and frontal–subcortical circuitry in obsessive–compulsive disorder
Saxena, S., Brody, A. L., Schwartz, J. M., & Baxter, L. R. (1998) · British Journal of Psychiatry · doi:10.1192/s0007125000297870 · Cited by 831 · see citing works
Obsessive-Compulsive Disorder in Children and Adolescents
Swedo, S. E. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810040041007 · Cited by 817 · see citing works
Symptoms of obsessive-compulsive disorder
(1997) · American Journal of Psychiatry · doi:10.1176/ajp.154.7.911 · Cited by 766 · see citing works
Mataix-Cols, D., Rauch, S. L., Manzo, P. A., Jenike, M. A., & Baer, L. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.9.1409 · Cited by 716 · see citing works
The Cross National Epidemiology of obsessive-compulsive disorder
Weisman, M. M., Bland, R. C., CANINO, G. J., Greenwald, S., Hwu, H., Lee, C. K., Newman, S. C., Browne, M. A. O., Rubio-Stipec, M., WICKRAMARATNE, P. J., et al. (1994) · Max Planck Institute for Plasma Physics · Cited by 688 · see citing works
Clinical characteristics and family history in DSM-III obsessive- compulsive disorder
(1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.3.317 · Cited by 668 · see citing works
A Family Study of Obsessive-compulsive Disorder
Nestadt, G., Samuels, J., Riddle, M., Bienvenu, O. J., Liang, K.-Y., LaBuda, M., Walkup, J., Grados, M., & Hoehn-Saric, R. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.4.358 · Cited by 657 · see citing works
Self-citationA 40-Year Follow-up of Patients With Obsessive-compulsive Disorder
Skoog, G., & Skoog, I. G. (1999) · Archives of General Psychiatry · doi:10.1001/archpsyc.56.2.121 · Cited by 634 · see citing works
Motor Inhibition and Cognitive Flexibility in Obsessive-Compulsive Disorder and Trichotillomania
Chamberlain, S. R., Fineberg, N. A., Blackwell, A. D., Robbins, T. W., & Sahakian, B. J. (2006) · American Journal of Psychiatry · doi:10.1176/ajp.2006.163.7.1282 · Cited by 627 · see citing works
Mapping complex disease loci in whole-genome association studies
Carlson, C. S., Eberle, M. A., Kruglyak, L., & Nickerson, D. A. (2004) · Nature · doi:10.1038/nature02623 · Cited by 616 · see citing works
The Future of Association Studies: Gene-Based Analysis and Replication
Neale, B. M., & Sham, P. C. (2004) · The American Journal of Human Genetics · doi:10.1086/423901 · Cited by 605 · see citing works
Haloperidol Addition in Fluvoxamine-Refractory Obsessive-Compulsive Disorder
McDougle, C. J. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950040046006 · Cited by 574 · see citing works
Gilles de la Tourette's Syndrome and Obsessive-Compulsive Disorder
Pauls, D. L. (1986) · Archives of General Psychiatry · doi:10.1001/archpsyc.1986.01800120066013 · Cited by 573 · see citing works
McDougle, C. J., Epperson, C. N., Pelton, G. H., Wasylink, S., & Price, L. H. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.8.794 · Cited by 571 · see citing works
Anxiety: New Research and Changing Concepts.
(1982) · Annals of Internal Medicine · doi:10.7326/0003-4819-96-3-407_5 · Cited by 556 · see citing works
Chamberlain, S. R., Menzies, L., Hampshire, A., Suckling, J., Fineberg, N. A., del Campo, N., Aitken, M., Craig, K., Owen, A. M., Bullmore, E. T., et al. (2008) · Science · doi:10.1126/science.1154433 · Cited by 550 · see citing works
Baer, L. (1994) · PubMed · Cited by 504 · see citing works
The Inheritance of Gilles de la Tourette's Syndrome and Associated Behaviors
Pauls, D. L., & Leckman, J. F. (1986) · New England Journal of Medicine · doi:10.1056/nejm198610163151604 · Cited by 494 · see citing works
Weissman, M. M., Bland, R. C., CANINO, G. J., Greenwald, S., Hwu, H., Lee, C. K., Newman, S. C., Oakley‐Browne, M., Rubio-Stipec, M., & WICKRAMARATNE, P. J. (1994) · PubMed · Cited by 486 · see citing works
Neurocognitive endophenotypes of obsessive-compulsive disorder
Menzies, L., Achard, S., Chamberlain, S. R., Fineberg, N., Chen, C.-H., del Campo, N., Sahakian, B. J., Robbins, T. W., & Bullmore, E. (2007) · Brain · doi:10.1093/brain/awm205 · Cited by 443 · see citing works
Chamberlain, S. R., Fineberg, N. A., Menzies, L. A., Blackwell, A. D., Bullmore, E. T., Robbins, T. W., & Sahakian, B. J. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.2.335 · Cited by 438 · see citing works
Efficacy of Fluvoxamine in Obsessive-Compulsive Disorder
Goodman, W. K. (1989) · Archives of General Psychiatry · doi:10.1001/archpsyc.1989.01810010038006 · Cited by 391 · see citing works
Hoyer, D., Pazos, Á., Probst, A., & Palacios, J. M. (1986) · Brain Research · doi:10.1016/0006-8993(86)90902-9 · Cited by 387 · see citing works
Clomipramine in the Treatment of Patients With Obsessive-Compulsive Disorder
(1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810320054008 · Cited by 386 · see citing works
Adults with early-onset obsessive-compulsive disorder
do Rosario-Campos, M. C., Leckman, J. F., Mercadante, M. T., Shavitt, R. G., Prado, H. D. S., Sada, P., Zamignani, D., & Miguel, E. C. (2001) · American Journal of Psychiatry · doi:10.1176/appi.ajp.158.11.1899 · Cited by 373 · see citing works
Glutamate transporter gene SLC1A1 associated with obsessive-compulsive disorder
Arnold, P. D., Sicard, T., Burroughs, E., Richter, M. A., & Kennedy, J. L. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.7.769 · Cited by 357 · see citing works
GELLER, D. A., Biederman, J., Jones, J. T., PARK, K., SCHWARTZ, S., SHAPIRO, S., & Coffey, B. J. (1998) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199804000-00020 · Cited by 344 · see citing works
Cerebral glucose metabolism in obsessive-compulsive hoarding
Saxena, S., Brody, A. L., Maidment, K. M., Smith, E. C., Zohrabi, N., Katz, E., Baker, S. K., & Baxter, L. R. (2004) · American Journal of Psychiatry · doi:10.1176/appi.ajp.161.6.1038 · Cited by 343 · see citing works
Hoarding in obsessive compulsive disorder: results from a case-control study
SAMUELS, J. F., Bienvenu, O. J., Riddle, M. A., Cullen, B., Grados, M. A., Liang, K., Hoehn‐Saric, R., & Nestadt, G. (2002) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(01)00026-2 · Cited by 337 · see citing works
Self-citationTics and Tourette's disorder: a 2- to 7-year follow-up of 54 obsessive- compulsive children
Leonard, H. L., Lenane, M., Swedo, S. E., Rettew, D. C., Gershon, E. S., & RAPOPORT, J. L. (1992) · American Journal of Psychiatry · doi:10.1176/ajp.149.9.1244 · Cited by 316 · see citing works
Frost, R. O., Steketee, G., Williams, L. F., & Warren, R. (2000) · Behaviour Research and Therapy · doi:10.1016/s0005-7967(99)00137-0 · Cited by 307 · see citing works
Karayiorgou, M., Altemus, M., Galke, B. L., Goldman, D., Murphy, D. L., Ott, J., & Gogos, J. A. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.9.4572 · Cited by 304 · see citing works
(1997) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.9.4.568 · Cited by 301 · see citing works
Carrasquillo, M. M., McCallion, A. S., Puffenberger, E. G., Kashuk, C., Nouri, N., & Chakravarti, A. (2002) · Nature Genetics · doi:10.1038/ng998 · Cited by 287 · see citing works
Obsessive Compulsive Disorder in Children and Adolescents: Phenomenology and Family History
Riddle, M. A., Scahill, L. D., King, R. A., Hardin, M. T., Towbin, K. E., Ort, S. I., Leckman, J. F., & Cohen, D. J. (1990) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199009000-00015 · Cited by 280 · see citing works
Cavedini, P., Riboldi, G., D'Annucci, A., Belotti, P., Cisima, M., & Bellodi, L. (2002) · Neuropsychologia · doi:10.1016/s0028-3932(01)00077-x · Cited by 277 · see citing works
Hall, D., Albers, A. D., Charalambous, A., Gogos, J. A., & Karayiorgou, M. (2003) · The American Journal of Human Genetics · doi:10.1086/377003 · Cited by 277 · see citing works
Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype
Ozaki, N., Goldman, D. A., Kaye, W. H., Plotnicov, K. H., Greenberg, B. D., Lappalainen, J., Rudnick, G., & Murphy, D. L. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001365 · Cited by 275 · see citing works
Dickel, D. E., Veenstra-VanderWeele, J., Cox, N. J., Wu, X., Fischer, D. J., Van Etten-Lee, M., Himle, J. A., Leventhal, B. L., Cook, E. H., & Hanna, G. L. (2006) · Archives of General Psychiatry · doi:10.1001/archpsyc.63.7.778 · Cited by 274 · see citing works
A family study of early-onset obsessive-compulsive disorder
do Rosário, M. C., Leckman, J. F., Cúri, M., Quatrano, S., Katsovitch, L., Miguel, E. C., & Pauls, D. L. (2005) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30149 · Cited by 272 · see citing works
Problems of Obsessional Illness
Lewis, A. J. (1936) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591573602900418 · Cited by 271 · see citing works
Karayiorgou, M., Sobin, C. A., Blundell, M. L., Galke, B. L., Malinova, L., Goldberg, P. H., Ott, J., & Gogos, J. A. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00319-9 · Cited by 263 · see citing works
LENANE, M. C., SWEDO, S. E., LEONARD, H., PAULS, D. L., SCEERY, W., & RAPOPORT, J. L. (1990) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199005000-00012 · Cited by 263 · see citing works
The Concept of the Ventral Striatum in Nonhuman Primates
HABER, S. N., & McFARLAND, N. R. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09259.x · Cited by 253 · see citing works
NESTADT, G., SAMUELS, J., RIDDLE, M. A., LIANG, K.-Y., BIENVENU, O. J., HOEHN-SARIC, R., GRADOS, M., & CULLEN, B. (2001) · Psychological Medicine · doi:10.1017/s0033291701003579 · Cited by 253 · see citing works
Self-citationPersonality disorders and normal personality dimensions in obsessive-compulsive disorder
Samuels, J., Nestadt, G., Bienvenu, O. J., Costa, P. T., Riddle, M. A., Liang, K.-Y., Hoehn-Saric, R., Grados, M. A., & Cullen, B. A. M. (2000) · British Journal of Psychiatry · doi:10.1192/bjp.177.5.457 · Cited by 237 · see citing works
Self-citationA family study of obsessive-compulsive disorder
Black, D. W. (1992) · Archives of General Psychiatry · doi:10.1001/archpsyc.1992.01820050026004 · Cited by 233 · see citing works
<i>Sapap3</i> and pathological grooming in humans: Results from the OCD collaborative genetics study
Bienvenu, O. J., Wang, Y., Shugart, Y. Y., Welch, J. M., Grados, M. A., Fyer, A. J., Rauch, S. L., McCracken, J. T., Rasmussen, S. A., Murphy, D. L., et al. (2009) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30897 · Cited by 207 · see citing works
Self-citationArnold, P., Rosenberg, D., Mundo, E., Tharmalingam, S., Kennedy, J., & Richter, M. (2004) · Psychopharmacology · doi:10.1007/s00213-004-1847-1 · Cited by 202 · see citing works
McDougle, C. J., Epperson, C. N., Price, L. H., & Gelernter, J. E. (1998) · Molecular Psychiatry · doi:10.1038/sj.mp.4000391 · Cited by 200 · see citing works
Hoarding in Obsessive-Compulsive Disorder
Winsberg, M. E., Cassic, K. S., & Koran, L. M. (1999) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.v60n0905 · Cited by 197 · see citing works
Multiple rare SAPAP3 missense variants in trichotillomania and OCD
Züchner, S., Wendland, J. R., Ashley-Koch, A. E., Collins, A. L., Tran-Viet, K. N., Quinn, K., Timpano, K. C., Cuccaro, M. L., Pericak-Vance, M. A., Steffens, D. C., et al. (2009) · Molecular Psychiatry · doi:10.1038/mp.2008.83 · Cited by 196 · see citing works
Grados, M. A., Riddle, M. A., SAMUELS, J. F., Liang, K., Hoehn‐Saric, R., Bienvenu, O. J., Walkup, J. T., Song, D., & Nestadt, G. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01074-5 · Cited by 195 · see citing works
Self-citationPsychiatric disorders in the families of patients with obsessive-compulsive disorder
Bellodi, L., Sciuto, G., Diaferia, G., Ronchi, P., & Smeraldi, E. (1992) · Psychiatry Research · doi:10.1016/0165-1781(92)90075-e · Cited by 189 · see citing works
Bengel, D., Greenberg, B. D., Cora‐Locatelli, G., Altemus, M., Heils, A., Li, Q., & Murphy, D. L. (1999) · Molecular Psychiatry · doi:10.1038/sj.mp.4000550 · Cited by 187 · see citing works
Association of the <i>SLC1A1</i> glutamate transporter gene and obsessive‐compulsive disorder
Stewart, S. E., Fagerness, J. A., Platko, J., Smoller, J. W., Scharf, J. M., Illmann, C., Jenike, E., Chabane, N., Leboyer, M., Delorme, R., et al. (2007) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30533 · Cited by 182 · see citing works
Disability and Family Burden in Obsessive—Compulsive Disorder
Steketee, G. S. (1997) · The Canadian Journal of Psychiatry · doi:10.1177/070674379704200902 · Cited by 182 · see citing works
Rauch, S. L. (2003) · Neurosurgery Clinics of North America · doi:10.1016/s1042-3680(02)00114-6 · Cited by 180 · see citing works
Replication Study Supports Evidence for Linkage to 9p24 in Obsessive-Compulsive Disorder
Willour, V. L., Shugart, Y. Y., SAMUELS, J. F., Grados, M. A., Cullen, B., Bienvenu, O. J., Wang, Y., Liang, K., Valle, D. L., Hoehn‐Saric, R., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/423899 · Cited by 170 · see citing works
Self-citationHasler, G., Pinto, A., Greenberg, B. D., SAMUELS, J. F., Fyer, A. J., Pauls, D. L., Knowles, J. A., McCracken, J. T., Piacentini, J. C., Riddle, M. A., et al. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.040 · Cited by 168 · see citing works
Self-citationSAMUELS, J. F., Shugart, Y. Y., Grados, M. A., Willour, V. L., Bienvenu, O. J., Greenberg, B. D., Knowles, J. A., McCracken, J. T., Rauch, S. L., Murphy, D. L., et al. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.3.493 · Cited by 165 · see citing works
Self-citationPinto, A., Greenberg, B. D., Grados, M. A., Bienvenu, O. J., Samuels, J. F., Murphy, D. L., Hasler, G., Stout, R. L., Rauch, S. L., Shugart, Y. Y., et al. (2008) · Psychiatry Research · doi:10.1016/j.psychres.2007.07.010 · Cited by 163 · see citing works
Self-citationShugart, Y. Y., SAMUELS, J. F., Willour, V. L., Grados, M. A., Greenberg, B. D., Knowles, J. A., McCracken, J. T., Rauch, S. L., Murphy, D., Wang, Y., et al. (2006) · Molecular Psychiatry · doi:10.1038/sj.mp.4001847 · Cited by 160 · see citing works
Self-citationAge at Onset and Causes of Disease
Childs, B., & Scriver, C. R. (1986) · Perspectives in biology and medicine · doi:10.1353/pbm.1986.0056 · Cited by 145 · see citing works
An exploratory study of the neural mechanisms of decision making in compulsive hoarding
Tolin, D. F., Kiehl, K. A., Worhunsky, P. D., Book, G. A., & Maltby, N. (2008) · Psychological Medicine · doi:10.1017/s0033291708003371 · Cited by 145 · see citing works
Wendland, J. R., Moya, P. R., Timpano, K. R., Anavitarte, A. P., Kruse, M. R., Wheaton, M. G., Ren-Patterson, R. F., & Murphy, D. L. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.6 · Cited by 145 · see citing works
Paediatric autoimmune neuropsychiatric disorders associated with streptococcal infection (PANDAS)
Leonard, H. L., & Swedo, S. E. (2001) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145701002371 · Cited by 144 · see citing works
Billett, E. A., Richter, M. A., King, N. A., Heils, A., Lesch, K., & Kennedy, J. L. (1997) · Molecular Psychiatry · doi:10.1038/sj.mp.4000257 · Cited by 143 · see citing works
Nestadt, G., Lan, T., SAMUELS, J. F., Riddle, M. A., Bienvenu, O. J., Liang, K., Hoehn‐Saric, R., Cullen, B., Grados, M. A., Beaty, T. H., et al. (2000) · The American Journal of Human Genetics · doi:10.1086/316898 · Cited by 138 · see citing works
Self-citationHudziak, J. J., van Beijsterveldt, C. E. M., Althoff, R. R., Stanger, C., Rettew, D. C., Nelson, E. C., Todd, R. D., Bartels, M., & Boomsma, D. I. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.6.608 · Cited by 135 · see citing works
Principal Components Analysis of Obsessive–Compulsive Disorder Symptoms in Children and Adolescents
Stewart, S. E., do Rosário, M. C., Brown, T. A., Carter, A. S., Leckman, J. F., Sukhodolsky, D. G., Katsovich, L., King, R. A., GELLER, D. A., & Pauls, D. L. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.08.040 · Cited by 133 · see citing works
Association between the COMT locus and obsessive-compulsive disorder in females but not males
Alsobrook, J. P., Zohar, A. H., Leboyer, M., Chabane, N., Ebstein, R. P., & Pauls, D. L. (2002) · American Journal of Medical Genetics · doi:10.1002/ajmg.10040 · Cited by 127 · see citing works
Cruz, C., Camarena, B., King, N., Páez, F., Sidenberg, D., de la Fuente, J. R., & Nicolini, H. (1997) · Neuroscience Letters · doi:10.1016/s0304-3940(97)00523-5 · Cited by 127 · see citing works
The identification of OCD-related subgroups based on comorbidity
Nestadt, G., Addington, A., Samuels, J., Liang, K.-Y., Bienvenu, O. J., Riddle, M., Grados, M., Hoehn-Saric, R., & Cullen, B. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(02)01677-3 · Cited by 123 · see citing works
Self-citationSIMILAR AND DISSIMILAR MANIFESTATIONS OF OBSESSIVE-COMPULSIVE NEUROSIS IN MONOZYGOTIC TWINS
Inouye, E. (1965) · American Journal of Psychiatry · doi:10.1176/ajp.121.12.1171 · Cited by 122 · see citing works
Frisch, A., Michaelovsky, E., Rockah, R., Amir, I., Hermesh, H., Laor, N., Fuchs, C., Zohar, J., Lerer, B., Buniak, S. F., et al. (2000) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(00)00071-7 · Cited by 118 · see citing works
Busatto, G. F., Buchpiguel, C. A., Zamignani, D. R., Garrido, G. J., Glabus, M. F., do Rosário, M. C., de Castro, C. C., Maia, A. K., da Rocha, E. T., McGuire, P. K., et al. (2001) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-200103000-00015 · Cited by 114 · see citing works
Obsessive–compulsive disorder: subclassification based on co-morbidity
Nestadt, G., Di, C., Riddle, M. A., Grados, M. A., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Rauch, S. L., Murphy, D. L., Rasmussen, S. A., et al. (2008) · Psychological Medicine · doi:10.1017/s0033291708004753 · Cited by 113 · see citing works
Self-citationShugart, Y. Y., Wang, Y., Samuels, J. F., Grados, M. A., Greenberg, B. D., Knowles, J. A., McCracken, J. T., Rauch, S. L., Murphy, D. L., Rasmussen, S. A., et al. (2009) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30914 · Cited by 112 · see citing works
Self-citationMeira‐Lima, I., Shavitt, R. G., Miguita, K., Ikenaga, E., Miguel, E. C., & Vallada, H. (2003) · Genes Brain & Behavior · doi:10.1046/j.1601-1848.2003.0042.x · Cited by 106 · see citing works
Obsessive-Compulsive Disorder in Children and Adolescents: A Review of the Past 10 Years
March, J. S., & Leonard, H. L. (1996) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199610000-00012 · Cited by 106 · see citing works
A Genetic Family-Based Association Study of OLIG2 in Obsessive-compulsive Disorder
Stewart, S. E., Platko, J. V., Fagerness, J. A., Birns, J., Jenike, E. A., Smoller, J. W., Perlis, R. H., Leboyer, M., Delorme, R., Chabane, N., et al. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.2.209 · Cited by 105 · see citing works
Sexually dimorphic relationship of a 5-HT2A promoter polymorphism with obsessive-compulsive disorder
Enoch, M., Greenberg, B. D., Murphy, D. L., & Goldman, D. A. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01040-4 · Cited by 103 · see citing works
Incidence of Obsessive-Compulsive Disorder in Adults
Nestadt, G., Bienvenu, O. J., Cai, G., SAMUELS, J. F., & Eaton, W. W. (1998) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-199807000-00003 · Cited by 103 · see citing works
Self-citationMundo, E., Richter, M. A., Zai, G. C., Sam, F., McBride, J., Macciardi, F. M., & Kennedy, J. L. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001059 · Cited by 102 · see citing works
Investigation of dopamine system genes in obsessive-compulsive disorder
Billett, E. A., Richter, M. A., Sam, F., Swinson, R. P., Dai, Y., King, N. A., Badri, F., Sasaki, T., Buchanan, J. A., & Kennedy, J. L. (1998) · Psychiatric Genetics · doi:10.1097/00041444-199800830-00005 · Cited by 101 · see citing works
Carlsson, M. L. (2000) · Acta Psychiatrica Scandinavica · doi:10.1034/j.1600-0447.2000.102006401.x · Cited by 96 · see citing works
Decision making performance in obsessive compulsive disorder
Nielen, M. M. A., Veltman, D. J., de Jong, R., Mulder, G., & den Boer, J. A. (2002) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00381-5 · Cited by 95 · see citing works
Hemmings, S. M. J. (2003) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00129-3 · Cited by 95 · see citing works
Walitza, S., Wewetzer, C., Warnke, A., Gerlach, M., Geller, F., Gerber, G., Görg, T., Herpertz‐Dahlmann, B., Schulz, E., Remschmidt, H., et al. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001105 · Cited by 95 · see citing works
Association between the dopamine receptor D4 (DRD4) gene and obsessive‐compulsive disorder
Millet, B., Chabane, N., Delorme, R., Leboyer, M., Leroy, S., Poirier, M. F., Bourdel, M., Mouren, M., Rouillon, F., Löo, H., et al. (2002) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10034 · Cited by 88 · see citing works
Cullen, B., Brown, C. H., Riddle, M. A., Grados, M. A., Bienvenu, O. J., Hoehn-Saric, R., Shugart, Y. Y., Liang, K., SAMUELS, J. F., & Nestadt, G. (2006) · Depression and Anxiety · doi:10.1002/da.20204 · Cited by 87 · see citing works
Self-citationProblems of Obsessional Illness: (Section of Psychiatry).
Lewis, A. J. (1936) · PubMed · Cited by 84 · see citing works
DRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder.
Nicolini, H., Cruz, C., Camarena, B., Orozco, B., Kennedy, J. L., King, N. A., Weissbecker, K., Fuente, J. R. D. L., & Sidenberg, D. G. (1996) · PubMed · Cited by 83 · see citing works
Obsessive–compulsive disorder, tics and anxiety in 6-year-old twins
Bolton, D., Rijsdijk, F. V., O’Connor, T. G., Perrin, S. G., & Eley, T. C. (2006) · Psychological Medicine · doi:10.1017/s0033291706008816 · Cited by 81 · see citing works
Camarena, B., Rinetti, G., Cruz, C., Cotero, A. G. G., Fuente, J. R. D. L., & Nicolini, H. (2001) · American Journal of Medical Genetics · doi:10.1002/ajmg.1323 · Cited by 80 · see citing works
Heredity in the Psychoneuroses ( Summary )
Brown, F. (1942) · Proceedings of the Royal Society of Medicine · doi:10.1177/003591574203501215 · Cited by 79 · see citing works
Parents of patients with obsessive-compulsive disorder
Insel, T. R., Hoover, C. F., & Murphy, D. L. (1983) · Psychological Medicine · doi:10.1017/s0033291700051515 · Cited by 78 · see citing works
Evidence for a Susceptibility Locus on Chromosome 10p15 in Early-Onset Obsessive-Compulsive Disorder
Hanna, G. L., Veenstra-VanderWeele, J. M., Cox, N. J., Etten, M. L. V., Fischer, D., Himle, J. A., Bivens, N. C., Wu, X., Roe, C. A., Hennessy, K., et al. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.01.008 · Cited by 77 · see citing works
Azzam, A., & Mathews, C. A. (2003) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20013 · Cited by 76 · see citing works
Myelin oligodendrocyte glycoprotein (MOG) gene is associated with obsessive‐compulsive disorder
Zai, G. C., Bezchlibnyk, Y. B., Richter, M. A., Arnold, P. D., Burroughs, E., Barr, C. L., & Kennedy, J. L. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30077 · Cited by 74 · see citing works
Obsessive-Compulsive Disorder, 5-HTTLPR polymorphism and treatment response
Bella, D. D., Erzegovesi, S., Cavallini, M. C., & Bellodi, L. (2002) · The Pharmacogenomics Journal · doi:10.1038/sj.tpj.6500090 · Cited by 73 · see citing works
MONOZYGOTIC TWINS WITH OBSESSIONAL ILLNESS
WOODRUFF, R., & Pitts, F. N. (1964) · American Journal of Psychiatry · doi:10.1176/ajp.120.11.1075 · Cited by 73 · see citing works
Obsessive Compulsive Neurosis in Identical Twins
Marks, I. M., Crowe, M., Drewe, E. A., Young, J., & Dewhurst, W. G. (1969) · The British Journal of Psychiatry · doi:10.1192/bjp.115.526.991 · Cited by 70 · see citing works
Zai, G., Arnold, P., Burroughs, E., Barr, C. L., Richter, M. A., & Kennedy, J. L. (2005) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30152 · Cited by 68 · see citing works
Association study of the serotonin transporter gene polymorphism in obsessive–compulsive disorder
Camarena, B., Rinetti, G., Cruz, C., Hernández, S., Fuente, J. R. D. L., & Nicolini, H. (2001) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145701002516 · Cited by 66 · see citing works
Families of Origin in Obsessive-Compulsive Disorder
Hoover, C. F., & Insel, T. R. (1984) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198404000-00004 · Cited by 65 · see citing works
Obsessions and compulsions in the community
Nestad, G., SAMUELS, J. F., Romanoski, A. J., Folstein, M. F., & McHugh, P. R. (1994) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1994.tb01504.x · Cited by 65 · see citing works
Self-citationApoE genotype is a risk factor in nonpresenilin early-onset alzheimer's disease families
Houlden, H., Crook, R., Backhovens, H., Prihar, G., Baker, M. C., Hutton, M., Rossor, M. N., Martin, J. J., Broeckhoven, C. V., & Hardy, J. (1998) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19980207)81:1 · Cited by 64 · see citing works
Familial Aspects of Obsessional Neurosis
Rosenberg, C. M. (1967) · The British Journal of Psychiatry · doi:10.1192/bjp.113.497.405 · Cited by 60 · see citing works
Niehaus, D. J. H., Kinnear, C. J., Corfield, V. A., du Toit, P. L., van Kradenburg, J., Moolman-Smook, J. C., Weyers, J. B., Potgieter, A., Seedat, S., Emsley, R. A., et al. (2001) · Journal of Affective Disorders · doi:10.1016/s0165-0327(00)00246-9 · Cited by 54 · see citing works
Chabane, N., Millet, B., Delorme, R., Lichtermann, D., Mathieu, F., Laplanche, J., Roy, I., Mouren, M. C., Hankard, R., Maier, W., et al. (2004) · Neuroscience Letters · doi:10.1016/j.neulet.2004.03.065 · Cited by 53 · see citing works
5HT2C CYS23/SER23 polymorphism is not associated with obsessive–compulsive disorder
Cavallini, M. C., Bella, D. D., Pasquale, L., Henin, M., & Bellodi, L. (1998) · Psychiatry Research · doi:10.1016/s0165-1781(97)00151-0 · Cited by 52 · see citing works
Delorme, R., Betancur, C., Wagner, M., Krebs, M., Gorwood, P. A. P. M., Pearl, P. L., Nygren, G., Durand, C. M., Buhtz, F., Pickering, P., et al. (2005) · Molecular Psychiatry · doi:10.1038/sj.mp.4001728 · Cited by 51 · see citing works
SAMUELS, J. F. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.164.3.493 · Cited by 49 · see citing works
Self-citationPulver, A. E., Liang, K., & Vogler, G. P. (1991) · Genetic Epidemiology · doi:10.1002/gepi.1370080506 · Cited by 48 · see citing works
Erdal, M. E., Tot, Ş., Yazıcı, K. U., Yazıcı, A., Herken, H., Erdem, P., Derici, E., & Ankaralı, H. Ç. (2003) · Depression and Anxiety · doi:10.1002/da.10114 · Cited by 48 · see citing works
A screen of SLC1A1 for OCD‐related alleles
Wang, Y., Adamczyk, A., Shugart, Y. Y., Samuels, J. F., Grados, M. A., Greenberg, B. D., Knowles, J. A., McCracken, J. T., Rauch, S. L., Murphy, D. L., et al. (2010) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31001 · Cited by 47 · see citing works
Self-citationSERT Ileu425Val in autism, Asperger syndrome and obsessive–compulsive disorder
Wendland, J. R., DeGuzman, T. B., McMahon, F. J., Rudnick, G., Detera‐Wadleigh, S. D., & Murphy, D. L. (2008) · Psychiatric Genetics · doi:10.1097/ypg.0b013e3282f08a06 · Cited by 46 · see citing works
Arolt, V., Lencer, R., Purmann, S., Sch�rmann, M., M�ller-Myhsok, B., Krecker, K., & SCHWINGER, E. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19991215)88:6 · Cited by 46 · see citing works
Catalano, M., Sciuto, G., Bella, D. D., Novelli, E., Nobile, M., & Bellodi, L. (1994) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320540312 · Cited by 44 · see citing works
Wang, Y., SAMUELS, J. F., Chang, Y.-P. C., Grados, M. A., Greenberg, B. D., Knowles, J. A., McCracken, J. T., Rauch, S. L., Murphy, D. L., Rasmussen, S. A., et al. (2008) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30760 · Cited by 34 · see citing works
Self-citationObsessive-Compulsive Neurosis: Two Identical Twin Pairs
McGuffin, P., & Mawson, D. C. (1980) · The British Journal of Psychiatry · doi:10.1192/bjp.137.3.285 · Cited by 33 · see citing works
Psychobiology of obsessive-compulsive disorder: anatomical and physiological considerations
Hoehn‐Saric, R., & Greenberg, B. D. (1997) · International Review of Psychiatry · doi:10.1080/09540269775565 · Cited by 33 · see citing works
ADVANCES IN THE NEUROBIOLOGY OF OBSESSIVE-COMPULSIVE DISORDER
Stein, D. J. (2000) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(05)70180-5 · Cited by 30 · see citing works
Ohashi, J., & Tokunaga, K. (2002) · PubMed · doi:10.1017/s0003480002001197 · Cited by 28 · see citing works
Ohashi, J., & Tokunaga, K. (2002) · Annals of Human Genetics · doi:10.1046/j.1469-1809.2002.00119.x · Cited by 22 · see citing works
Genetic epidemiology of breast cancer in younger women.
Eb, C. (1994) · PubMed · Cited by 21 · see citing works
Obsessive-Compulsive Disorder and Paraphilia in a Monozygotic Twin Pair
Cryan, E. M. J., Butcher, G. J., & Webb, M. G. T. (1992) · The British Journal of Psychiatry · doi:10.1192/bjp.161.5.694 · Cited by 19 · see citing works
Middlemass, J. (1903) · Europe PMC (PubMed Central) · Cited by 11 · see citing works
Kallmann syndrome gene (KAL-X) is not mutated in schizophrenia
O’Neill, M. J., Brewer, W. J., Thornley, C., Copolov, D., Warne, G. L., Sinclair, A. H., Forrest, S., & Williamson, R. (1999) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19990205)88:1 · Cited by 7 · see citing works
Biochemical Research in Two Cases of Endogenous Pellagra
Voiculescu, V., LUCA, N., & Haţegan, D. (2008) · European Neurology · doi:10.1159/000114277 · Cited by 1 · see citing works
Jonnal (2000) · doi:10.1002/1096-8628(20001204)96:6
Flagged first, then by citations
Research works printed but not linked: 3
- [6]Murray CL Lopez AD The Global Burden of Disease 1996 Harvard University Press Cambridge
- [36]Hanna G Abstract. Biological Psychiatry Conference May 2000 2004
- [81]Schindler KM Richter MA Kennedy JL Association between homozygosity at the COMT gene locus and obsessive compulsive disorder Am.J.Med.Genet 2000 96 721 724 11121168
Cited by
Sorted by citations
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS
Mattheisen, M., Samuels, J. F., Wang, Y., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Geller, D. A., Murphy, D. L., Knowles, J. A., Grados, M. A., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.43 · Cited by 321 · see citing works
Self-citationTowards a post-traumatic subtype of obsessive-compulsive disorder
Fontenelle, L. F., Cocchi, L., Harrison, B. J., Shavitt, R. G., do Rosário, M. C., Ferrão, Y. A., de Mathis, M. A., Cordioli, A. V., Yücel, M., Pantelis, C., et al. (2012) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2011.12.001 · Cited by 121 · see citing works
The neurobiological link between OCD and ADHD
Brem, S., Grünblatt, E., Drechsler, R., Riederer, P., & Walitza, S. (2014) · ADHD Attention Deficit and Hyperactivity Disorders · doi:10.1007/s12402-014-0146-x · Cited by 109 · see citing works
Stewart, S. E., Mayerfeld, C., Arnold, P. D., Crane, J. R., O'Dushlaine, C., Fagerness, J. A., Yu, D., Scharf, J. M., Chan, E., Kassam, F., et al. (2013) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32137 · Cited by 102 · see citing works
Self-citationSamuels, J., Wang, Y., Riddle, M. A., Greenberg, B. D., Fyer, A. J., McCracken, J. T., Rauch, S. L., Murphy, D. L., Grados, M. A., Knowles, J. A., et al. (2011) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.31184 · Cited by 89 · see citing works
Self-citationRajender, G., Bhatia, M. S., Kanwal, K., Malhotra, S., Singh, T. B., & Chaudhary, D. (2011) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.2011.01733.x · Cited by 84 · see citing works
Bokor, G., & Anderson, P. D. (2014) · Journal of Pharmacy Practice · doi:10.1177/0897190014521996 · Cited by 79 · see citing works
Zhang, L., Dong, Y., Ji, Y., Zhu, C., Yu, F., Ma, H., Chen, X., & Wang, K. (2015) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2014.09.005 · Cited by 59 · see citing works
Porton, B., Greenberg, B. D., Askland, K., Serra, L. M., Gesmonde, J., Rudnick, G., Rasmussen, S. A., & Kao, H.-T. (2013) · Translational Psychiatry · doi:10.1038/tp.2013.35 · Cited by 36 · see citing works
Maternal Effects as Causes of Risk for Obsessive-Compulsive Disorder
Mahjani, B., Klei, L., Hultman, C. M., Larsson, H., Devlin, B., Buxbaum, J. D., Sandin, S., & Grice, D. E. (2020) · Biological Psychiatry · doi:10.1016/j.biopsych.2020.01.006 · Cited by 36 · see citing works
Zhang, L., Dong, Y., Ji, Y., Tao, R., Chen, X., Ye, J., Zhang, L., Yu, F., Zhu, C., & Wang, K. (2015) · Scientific Reports · doi:10.1038/srep17312 · Cited by 26 · see citing works
Imbalance between the caudate and putamen connectivity in obsessive–compulsive disorder
Peng, Z., He, T., Ren, P., Jin, L., Yang, Q., Xu, C., Wen, R., Chen, J., Wei, Z., Verguts, T., et al. (2022) · NeuroImage: Clinical · doi:10.1016/j.nicl.2022.103083 · Cited by 20 · see citing works
Comparison of neurocognitive performance in familial versus sporadic obsessive-compulsive disorder
Bhattacharya, M., Balachander, S., Viswanath, B., & Reddy, Y. C. J. (2021) · Journal of Obsessive-Compulsive and Related Disorders · doi:10.1016/j.jocrd.2021.100666 · Cited by 5 · see citing works
- Authors
- Nestadt, G., Grados, M., & Samuels, J. F.
- Affiliations
- Johns Hopkins University (US)
- Corresponding author
- Nestadt, Gerald
- Venue
- Psychiatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 33
- Issue
- 1
- Pages
- 141-158
- ISSN
- 0193-953X (ISSN-L)
- PMC
- PMC2824902
- OpenAlex
- W2129988353
- Cited by
- 105
- References
- 149
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 5 · 2023: 3 · 2022: 7 · 2021: 11 · 2020: 7 · 2019: 5 · 2018: 9 · 2017: 5 · 2016: 4 · 2015: 12 · 2014: 10 · 2013: 7 · 2012: 3
- FWCI
- 0.84
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychiatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Mental Health (R01MH050214, R01MH071507, R01 MH 50214)
- National Center for Research Resources (RR 000 52)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- obsessive-compulsive disorder, genetics, genetic etiology, multifactorial inheritance, environmental risk factors, candidate genes, molecular genetics
- MeSH terms
- Environment, Humans, Genetic Linkage, Obsessive-Compulsive Disorder, Phenotype, Genetic Association Studies
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