Personality disorders and normal personality dimensions in obsessive-compulsive disorder
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Background: Little is known about personality disorders and normal personality dimensions in relatives of patients with obsessive-compulsive disorder (OCD). Aims: To determine whether specific personality characteristics are part of a familial spectrum of OCD. Method: Clinicians evaluated personality disorders in 72 OCD case and 72 control probands and 198 case and 207 control first-degree relatives. The self-completed Revised NEO Personality Inventory was used for assessment of normal personality dimensions. The prevalence of personality disorders and scores on normal personality dimensions were compared between case and control probands and between case and control relatives. Results: Case probands and case relatives had a high prevalence of obsessive-compulsive personality disorder (OCPD) and high neuroticism scores. Neuroticism was associated with OCPD in case but not control relatives. Conclusions: Neuroticism and OCPD may share a common familial aetiology with OCD.
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In previous studies, higher neuroticism and lower extraversion has been reported frequently for patients with OCD.
“In previous studies, higher neuroticism and lower extraversion has been reported frequently for patients with OCD [62, 63].”
From P300 and delay-discounting in obsessive–compulsive disorder (2022) · cites this paper as [63]
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- Authors
- Samuels, J., Nestadt, G., Bienvenu, O. J., Costa, P. T., Riddle, M. A., Liang, K.-Y., Hoehn-Saric, R., Grados, M. A., & Cullen, B. A. M.
- Affiliations
- Johns Hopkins University (US)
- National Institute on Aging (US)
- Corresponding author
- Samuels, Jack
- ORCID
- Venue
- British Journal of Psychiatry
- Publisher
- Royal College of Psychiatrists
- Published
- 2000-11
- Volume
- 177
- Issue
- 5
- Pages
- 457-462
- ISSN
- 0007-1250 (ISSN-L)
- 1472-1465
- OpenAlex
- W2087316091
- Cited by
- 237
- References
- 27
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 8 · 2023: 8 · 2022: 3 · 2021: 9 · 2020: 7 · 2019: 7 · 2018: 12 · 2017: 15 · 2016: 5 · 2015: 17 · 2014: 12 · 2013: 16 · 2012: 8
- FWCI
- 7.59
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The British Journal of Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Deutsches Krebsforschungszentrum
- National Institutes of Health (NIH/NCRR/OPD‐GCRC RR00052, RR-00052)
- National Institute of Mental Health (R01MH050214, R01 MH 50214)
- National Center for Research Resources (RR 000 52, OPD-GCRC RR00052)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Keywords
- obsessive-compulsive disorder, obsessive-compulsive personality disorder, personality disorders, neuroticism, first-degree relatives, family transmission, personality factors, NEO-PI-R
- MeSH terms
- Adult, Female, Humans, Male, Neurotic Disorders, Obsessive-Compulsive Disorder, Personality, Personality Disorders, Psychiatric Status Rating Scales, Psychometrics, Case-Control Studies, Single-Blind Method
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