Clinical characteristics and family history in DSM-III obsessive- compulsive disorder

Steven A. Rasmussen; Ming T. Tsuang

doi:10.1176/ajp.143.3.317

Cited by 668Obsessive-Compulsive Spectrum DisordersPsychoanalysis and Psychopathology ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Clinical characteristics and family history in DSM-III obsessive- compulsive disorder

Steven A. Rasmussen, Ming T. Tsuang·1986·American Journal of Psychiatry

DOI 10.1176/ajp.143.3.317

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Abstract

The authors present the clinical characteristics, demographic features, and family history of a clinical sample of 44 patients who met DSM-III criteria for obsessive-compulsive disorder. Their findings are consistent with those of previous epidemiologic studies completed before the introduction of DSM-III with regard to phenomenology, course, and demographic characteristics. Most of the 44 patients had concomitant or lifetime histories of a major depressive disorder or another anxiety disorder. A number of first-degree relatives of these patients had probable obsessive-compulsive disorder or obsessive traits. The findings of this study should prove useful in further epidemiologic, biologic, and behavioral studies.

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The mean duration between onset of first OCD symptoms and presentation for treatment is around seven years.
“The mean duration between onset of first OCD symptoms and presentation for treatment is around seven years [19, 20].”
From Study protocol for a randomised controlled trial of internet-based cognitive-behavioural therapy for obsessive-compulsive disorder (2014) · cites this paper as [20]

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Systematic review of environmental risk factors for Obsessive-Compulsive Disorder: A proposed roadmap from association to causation
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“…M. Lohr c, Tom Armstrong a a Vanderbilt University, United States b University of Texas-Austin, United States c University of Arkansas, United States Contamination fear is a commonly observed phenomenon in obsessive-compulsive disorder (OCD; Rachman & Hodgson, 1980; Rasmussen & Tsuang, 1986).”
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Childhood-onset obsessive-compulsive disorder
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“Several studies have found that stressful life events were linked to the onset of OCD (McKeon et al. 1984 ; Khanna et al. 1988 ; Toro et al. 1992), although Rasmussen & Tsuang (1986) found that most OCD participants were unable to identify an environmental precipitant.”
Background
Gender-Divergent Aetiological Factors in Obsessive-Compulsive Disorder
Noshirvani, H., Kasvikis, Y., Marks, I. M., Tsakiris, F. E., & Monteiro, W. (1991) · The British Journal of Psychiatry · doi:10.1192/bjp.158.2.260 · Cited by 145 · see citing works
“Some literature suggeststhat early onset is a bad prognostic factor (Strauss, 1948; Ingram, 1961; Rasmussen & Tsuang, 1986) and associated with greater severity of the disorder (de Silva et a!, 1977).”
Background
The genetics of obsessive compulsive disorder: a review of the evidence
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“In a descriptive study of 44 OCD patients (Rasmussen & Tsuang, 1986), 14 (32”
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Personality traits in subclinical and non-obsessive-compulsive volunteers and their parents
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“, 1999), symmetry and exactness (Lensi et al., 1996; Rasmussen and Tsuang, 1986), concern with numbers (Skoog, 1965; Swedo and Rapoport, 1989), touching rituals (Fischer et al.”
Background
The Role of Stress in the Pathogenesis and Maintenance of Obsessive-Compulsive Disorder
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“…of these barriers, specifically stigma and shame, most OCD sufferers wait 8–10 years before seeking treatment (Marques et al., 2010; Pallanti, 2008; Rasmussen & Tsuang, 1986), and as few as 29% of the afflicted population obtain treatment specifically for their OCD (NCS-R; Ruscio et al., 2010).”
Developmental psychopathology of children and adolescents with Tourette syndrome – impact of ADHD
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Authors: Rasmussen, S. A., & Tsuang, M. T.
Affiliations: Butler Hospital (US)
ORCID: Steven A. Rasmussen
Ming T. Tsuang
Venue: American Journal of Psychiatry
Publisher: American Psychiatric Association Publishing
Published: 1986-03-01
Volume: 143
Issue: 3
Pages: 317-322
ISSN: 0002-953X (ISSN-L)
1535-7228
DOI: 10.1176/ajp.143.3.317
OpenAlex: W1679486966
Cited by: 668
References: 22
Citations by year: 2026: 5 · 2025: 3 · 2024: 5 · 2023: 9 · 2022: 4 · 2021: 5 · 2020: 11 · 2019: 6 · 2018: 8 · 2017: 15 · 2016: 14 · 2015: 17 · 2014: 19 · 2013: 15 · 2012: 51
FWCI: 17.14
Type: journal article
Language: en
Open access: closed
Locations: American Journal of Psychiatry (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute of Mental Health (MH38096, MH38079)
Topics: Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords: obsessive-compulsive disorder, DSM-III criteria, clinical features, family history (medicine), first-degree relatives, comorbid depression, anxiety disorders, demographic factors, clinical course
MeSH terms: Adolescent, Adult, Anxiety Disorders, Depressive Disorder, Female, Humans, Male, Manuals as Topic, Obsessive-Compulsive Disorder, Risk, Schizophrenia

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Clinical characteristics and family history in DSM-III obsessive- compulsive disorder

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