eyeworm: an original endo- and ecto-parasitic nematode
Abstract
The genus Thelazia comprises several parasites, commonly named eyeworms, which infect the eyes and associated tissues of mammals, including humans. Transmission of eyeworms occurs via non-biting diptera that feed on the ocular secretions, tears and conjunctiva of animals. The disease, thelaziosis, is characterized by a range of subclinical to clinical signs, such as epiphora, conjunctivitis, keratitis, corneal opacity and ulcers. Human thelaziosis is common in poor socio-economic settings in many Asian countries. The relationship between eyeworms and their hosts are discussed here, together with recent molecular insights that are instrumental in investigating the biology of Thelazia in their definitive and intermediate hosts.
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From Pet roundworms and hookworms: A continuing need for global worming (2012) · cites this paper as [2]
Cites
Nematode parasites of vertebrates: their development and transmission
Anderson, R. C. (2000) · CABI Publishing eBooks · doi:10.1079/9780851994215.0000 · Cited by 2,487 · see citing works
The Nematode Parasites of Vertebrates
Yorke, W., & Maplestone, P. A. (1926) · Transactions of the American Microscopical Society · doi:10.2307/3221805 · Cited by 774 · see citing works
Otranto, D., Ferroglio, E., Lia, R. P., Traversa, D., & Rossi, L. (2003) · Veterinary Parasitology · doi:10.1016/j.vetpar.2003.07.022 · Cited by 120 · see citing works
Self-citationOtranto, D., Lia, R. P., BUONO, V., Traversa, D., & Giangaspero, A. (2004) · Parasitology · doi:10.1017/s0031182004006018 · Cited by 118 · see citing works
Self-citationPCR-based technology in veterinary parasitology
Gasser, R. B. (1999) · Veterinary Parasitology · doi:10.1016/s0304-4017(99)00036-9 · Cited by 103 · see citing works
Morales‐Hojas, R., Post, R. J., Shelley, A. J., et al. (2001) · International Journal for Parasitology · doi:10.1016/s0020-7519(00)00156-9 · Cited by 64 · see citing works
Otranto, D., Tarsitano, E., Traversa, D., et al. (2001) · International Journal for Parasitology · doi:10.1016/s0020-7519(01)00279-x · Cited by 44 · see citing works
Self-citationOtranto, D., Tarsitano, E., Traversa, D., et al. (2003) · Parasitology · doi:10.1017/s0031182003003913 · Cited by 44 · see citing works
Self-citationTraversa, D., Giangaspero, A., Galli, P., Paoletti, B., Otranto, D., & Gasser, R. B. (2004) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2004.01.006 · Cited by 35 · see citing works
Self-citationOtranto, D., & Traversa, D. (2004) · Journal of Parasitology · doi:10.1645/ge-115r1 · Cited by 34 · see citing works
Self-citationShi, Y., Han, J., Yang, W., & Wei, D. X. (1988) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(88)90535-4 · Cited by 30 · see citing works
A survey of thelazia worms in the eyelids of British cattle
Arbuckle, J., & Khalil, L. F. (1978) · Veterinary Record · doi:10.1136/vr.102.10.207 · Cited by 28 · see citing works
O’Hara, J. E., & Kennedy, M. J. (1991) · Journal of Parasitology · doi:10.2307/3283130 · Cited by 28 · see citing works
Lyons, Ε. T., Drudge, J. H., & Tolliver, S. C. (1976) · Journal of Parasitology · doi:10.2307/3279177 · Cited by 25 · see citing works
Geden, C. J., & Stoffolano, J. G. (1981) · Journal of Medical Entomology · doi:10.1093/jmedent/18.6.449 · Cited by 20 · see citing works
O’Hara, J. E., & Kennedy, M. J. (1989) · Journal of Parasitology · doi:10.2307/3283068 · Cited by 16 · see citing works
Smeal, M. G. (1968) · Australian Veterinary Journal · doi:10.1111/j.1751-0813.1968.tb09004.x · Cited by 16 · see citing works
The life-cycle of the nematode, Thelazia callipaeda parasitic in the eye of man and carnivores.
Kozlov, D. P. (1962) · Cited by 15 · see citing works
Nematodes Associated with the Genus Musca (Diptera: Muscidae)
Stoffolano, J. G. (1970) · Bulletin of the Entomological Society of America · doi:10.1093/besa/16.4.194 · Cited by 14 · see citing works
Wang, Z.-X., Hu, Y., Shen, J.-L., et al. (2003) · PubMed · Cited by 14 · see citing works
Ikeme, M. M. (1967) · PubMed · Cited by 11 · see citing works
Thelazia callipaeda from man and dogs in Kyoto and its scanning electron microscopy.
Arizono, N. (1976) · Kiseichūgaku zasshi · Cited by 10 · see citing works
Világiová, I. (1967) · Folia Parasitologica · Cited by 10 · see citing works
Klësov, M. D. (1950) · Cited by 5 · see citing works
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Traversa, D. (2012) · Parasites & Vectors · doi:10.1186/1756-3305-5-91 · Cited by 221 · see citing works
Self-citationZoonotic helminths affecting the human eye
Otranto, D., & Eberhard, M. L. (2011) · Parasites & Vectors · doi:10.1186/1756-3305-4-41 · Cited by 203 · see citing works
Self-citationOtranto, D., Cantacessi, C., Testini, G., & Lia, R. P. (2006) · International Journal for Parasitology · doi:10.1016/j.ijpara.2006.06.006 · Cited by 157 · see citing works
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Otranto, D., Sakru, N., Testini, G., Gürlü, V. P., Yakar, K., Lia, R. P., Dantas-Torres, F., & Bain, O. (2011) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2011.10-0465 · Cited by 110 · see citing works
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Miró, G., Montoya, A., Hernández, L., Dado, D., Vázquez, M. V., Benito, M., Villagrasa, M., Brianti, E., & Otranto, D. (2011) · Parasites & Vectors · doi:10.1186/1756-3305-4-148 · Cited by 99 · see citing works
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Vieira, L., Rodrigues, F. T., Costa, Á., Diz-Lopes, D., Machado, J., Coutinho, T., Tuna, J., Latrofa, M. S., Cardoso, L., & Otranto, D. (2012) · Parasites & Vectors · doi:10.1186/1756-3305-5-124 · Cited by 61 · see citing works
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Ruytoor, P., Déan, E., Pennant, O., Dorchies, P., Chermette, R., Otranto, D., & Guillot, J. (2010) · Emerging Infectious Diseases · doi:10.3201/eid1612.100872 · Cited by 43 · see citing works
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- Authors
- OTRANTO, D., & TRAVERSA, D.
- Affiliations
- University of Bari Aldo Moro (IT)
- University of Teramo (IT)
- Corresponding author
- OTRANTO, D
- Venue
- Trends in Parasitology
- Publisher
- Elsevier BV
- Published
- 2005-01
- Volume
- 21
- Issue
- 1
- Pages
- 1-4
- ISSN
- 1471-4922 (ISSN-L)
- OpenAlex
- W1502886833
- Cited by
- 167
- References
- 24
- Citations by year
- 2026: 8 · 2025: 14 · 2024: 16 · 2023: 8 · 2022: 6 · 2021: 17 · 2020: 12 · 2019: 5 · 2018: 11 · 2017: 3 · 2016: 8 · 2015: 12 · 2014: 7 · 2013: 2 · 2012: 8
- FWCI
- 3.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Parasitology (publishedVersion)
- PubMed (publishedVersion)
- CINECA IRIS Institutional Research Information System (University of Bari Aldo Moro) (submittedVersion)
- Topics
- Health Sciences › Medicine › Infectious Diseases › Parasitic Diseases Research and Treatment
- Health Sciences › Veterinary › Small Animals › Helminth infection and control
- Physical Sciences › Environmental Science › Ecology › Parasite Biology and Host Interactions
- Keywords
- Thelazia, eye worm, thelaziosis, parasitic nematodes, ocular parasitic infection, epiphora, conjunctivitis, keratitis, host-parasite interactions, intermediate hosts, definitive host
- MeSH terms
- Animals, Cattle, Diptera, Dogs, Female, Geography, Host-Parasite Interactions, Humans, Insect Vectors, Life Cycle Stages, Male, Mammals, Species Specificity, Thelazioidea, Eye Infections, Parasitic, Spirurida Infections
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