Life expectancy among persons with schizophrenia or bipolar affective disorder
Abstract
Context Mortality rates among individuals with schizophrenia or bipolar disorder are elevated compared to the general population.Objective The objective was to estimate life-expectancy (average age at death) among these persons and make a comparison to people in the general population.Methods Life-expectancy was calculated by means of survival analysis techniques using the entire Danish population as a cohort.Results Life-expectancy was 18.7 years shorter for schizophrenic men compared to men in the general population. Corresponding numbers for schizophrenic women was 16.3 years, for bipolar men 13.6 years, and for bipolar women 12.1 years.Conclusions Life-expectancy was much shorter in persons with schizophrenia or bipolar disorder. Excess mortality from physical diseases and medical conditions exerts a far greater influence on the curtailed life-expectancy, when compared against the impact of death by external causes.
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In patients with bipolar disorder there was a reduction in life expectancy of 12 to 14 years.
“In patients with bipolar disorder there was a reduction in life expectancy of 12e14 years.440”
From 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias (2016) · cites this paper as [440]
The reductions of life expectancy among persons with bipolar disorder seem to be slightly smaller: approximately 10 years in a study from London, and 13 years in a Danish study made on data similar to the Danish data used in Table 3.
“The reductions of life expectancy among persons with bipolar disorder seem to be slightly smaller: approximately 10 years in a study from London [43], and 13 years in a Danish study made on data similar to the Danish data used in Table 3 [44].”
From Life expectancy and death by diseases of the circulatory system in patients with bipolar disorder or schizophrenia in the Nordic countries. (2013) · cites this paper as [44]
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- Authors
- Laursen, T. M.
- Affiliations
- Aarhus University (DK)
- Corresponding author
- Laursen, Thomas Munk
- ORCID
- Laursen, Thomas Munk
- Venue
- Schizophrenia Research
- Publisher
- Elsevier BV
- Published
- 2011-09
- Volume
- 131
- Issue
- 1-3
- Pages
- 101-104
- ISSN
- 0920-9964 (ISSN-L)
- OpenAlex
- W2101226830
- Cited by
- 508
- References
- 16
- Citations by year
- 2026: 18 · 2025: 25 · 2024: 23 · 2023: 38 · 2022: 39 · 2021: 45 · 2020: 45 · 2019: 42 · 2018: 26 · 2017: 43 · 2016: 42 · 2015: 44 · 2014: 27 · 2013: 36 · 2012: 12
- FWCI
- 17.04
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Schizophrenia Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Social Psychology › Mental Health Treatment and Access
- Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
- Keywords
- life expectancy, schizophrenia
- MeSH terms
- Adolescent, Adult, Aged, Aged, 80 and over, Bipolar Disorder, Denmark, Female, Humans, Life Expectancy, Male, Middle Aged, Schizophrenia, Sex Factors, Community Health Planning, Young Adult
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