Resisting medicines: a synthesis of qualitative studies of medicine taking
Abstract
The study aimed to synthesise qualitative studies of lay experiences of medicine taking. Most studies focused on the experience of those not taking their medicine as prescribed, with few considering those who reject their medicines or accept them uncritically. Most were concerned with medicines for chronic illnesses. The synthesis revealed widespread caution about taking medicines and highlighted the lay practice of testing medicines, mainly for adverse effects. Some concerns about medicines cannot be resolved by lay evaluation, however, including worries about dependence, tolerance and addiction, the potential harm from taking medicines on a long-term basis and the possibility of medicines masking other symptoms. Additionally, in some cases medicines had a significant impact on identity, presenting problems of disclosure and stigma. People were found to accept their medicines either passively or actively, or to reject them. Some were coerced into taking medicines. Active accepters might modify their regimens by taking medicines symptomatically or strategically, or by adjusting doses to minimise unwanted consequences, or to make the regimen more acceptable. Many modifications appeared to reflect a desire to minimise the intake of medicines and this was echoed in some peoples' use of non-pharmacological treatments to either supplant or supplement their medicines. Few discussed regimen changes with their doctors. We conclude that the main reason why people do not take their medicines as prescribed is not because of failings in patients, doctors or systems, but because of concerns about the medicines themselves. On the whole, the findings point to considerable reluctance to take medicine and a preference to take as little as possible. We argue that peoples' resistance to medicine taking needs to be recognised and that the focus should be on developing ways of making medicines safe, as well as identifying and evaluating the treatments that people often choose in preference to medicines.
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Meta-ethnography has been used solely to synthesise qualitative studies, and has typically been used only with small samples.
“Meta-ethnography, an approach in which there has been recent significant activity and innovation, has similarly been used solely to synthesise qualitative studies, and has typically been used only with small samples [9-11].”
From Conducting a critical interpretive synthesis of the literature on access to healthcare by vulnerable groups (2006) · cites this paper as [9]
Meta-ethnography had previously only been used to synthesise qualitative studies.
“However, this had previously only been used to synthesise qualitative studies.”
From Conducting a critical interpretive synthesis of the literature on access to healthcare by vulnerable groups (2006) · cites this paper as [9]
People are actively involved in making meaning of their medication use, and this has implications for the value it has in their lives.
“there is an important body of research recognising that people are actively involved in making meaning of their medication use and that this has implications this has for the value it has in their lives”
From ‘In my life antidepressants have been…’: a qualitative analysis of users’ diverse experiences with antidepressants (2016) · cites this paper as [9]
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- Authors
- Pound, P., Britten, N., Morgan, M., Yardley, L., Pope, C., Daker-White, G., & Campbell, R.
- Affiliations
- University of Bristol (GB)
- University of Exeter (GB)
- University of Southampton (GB)
- Corresponding author
- Campbell, Rona
- Venue
- Social Science & Medicine
- Publisher
- Elsevier BV
- Published
- 2005-07
- Volume
- 61
- Issue
- 1
- Pages
- 133-155
- ISSN
- 0277-9536 (ISSN-L)
- OpenAlex
- W2103844098
- Cited by
- 868
- References
- 69
- Citations by year
- 2026: 9 · 2025: 11 · 2024: 22 · 2023: 39 · 2022: 9 · 2021: 45 · 2020: 30 · 2019: 69 · 2018: 37 · 2017: 56 · 2016: 51 · 2015: 47 · 2014: 71 · 2013: 56 · 2012: 48
- FWCI
- 31.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Social Science & Medicine (publishedVersion)
- PubMed (publishedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- ePrints Soton (University of Southampton) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Research Explorer (The University of Manchester) (submittedVersion)
- Bristol Research (University of Bristol) (submittedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Health Professions › General Health Professions › Patient-Provider Communication in Healthcare
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacy and Medical Practices
- Keywords
- non-compliance, chronic disease, adverse drug reactions, symptom masking, non-pharmacological treatment, patient-physician communication, drug safety
- MeSH terms
- Adult, Aged, Pharmaceutical Preparations, Evaluation Studies as Topic, Female, United Kingdom, Humans, Male, Middle Aged, Patient Compliance, Self Administration, Treatment Refusal, Drug-Related Side Effects and Adverse Reactions
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