Conducting a meta-ethnography of qualitative literature: Lessons learnt
Open accessAbstract
BACKGROUND: Qualitative synthesis has become more commonplace in recent years. Meta-ethnography is one of several methods for synthesising qualitative research and is being used increasingly within health care research. However, many aspects of the steps in the process remain ill-defined. DISCUSSION: We utilized the seven stages of the synthesis process to synthesise qualitative research on adherence to tuberculosis treatment. In this paper we discuss the methodological and practical challenges faced; of particular note are the methods used in our synthesis, the additional steps that we found useful in clarifying the process, and the key methodological challenges encountered in implementing the meta-ethnographic approach. The challenges included shaping an appropriate question for the synthesis; identifying relevant studies; assessing the quality of the studies; and synthesising findings across a very large number of primary studies from different contexts and research traditions. We offer suggestions that may assist in undertaking meta-ethnographies in the future. SUMMARY: Meta-ethnography is a useful method for synthesising qualitative research and for developing models that interpret findings across multiple studies. Despite its growing use in health research, further research is needed to address the wide range of methodological and epistemological questions raised by the approach.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Efforts were made to retain the nature and context of the original studies throughout data extraction, analysis and reporting.
“Efforts were made to retain the nature and context of the original studies throughout data extraction, analysis and reporting (Atkins et al., 2008).”
From Young people’s conceptualizations of the nature of cyberbullying: A systematic review and synthesis of qualitative research (2020) · cites this paper as Atkins et al., 2008
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Qualitative research: standards, challenges, and guidelines
Malterud, K. (2001) · The Lancet · doi:10.1016/s0140-6736(01)05627-6 · Cited by 5,014 · see citing works
Qualitative methods for health research
Green, J., & Thorogood, N. (2009) · Choice Reviews Online · doi:10.5860/choice.47-0901 · Cited by 4,607 · see citing works
Qualitative research in health care: Assessing quality in qualitative research
Mays, N. (2000) · BMJ · doi:10.1136/bmj.320.7226.50 · Cited by 3,742 · see citing works
Noblit, G., & Hare, R. (1988) · doi:10.4135/9781412985000 · Cited by 2,723 · see citing works
Checklists for improving rigour in qualitative research: a case of the tail wagging the dog?
Barbour, R. S. (2001) · BMJ · doi:10.1136/bmj.322.7294.1115 · Cited by 2,613 · see citing works
Meta-Ethnography: Synthesizing Qualitative Studies
Noblit, G. W., & Hare, R. D. (1988) · Medical Entomology and Zoology · Cited by 2,191 · see citing works
Synthesising qualitative and quantitative evidence: A review of possible methods
Dixon-Woods, M., Agarwal, S., Jones, D., Young, B., & Sutton, A. (2005) · Journal of Health Services Research & Policy · doi:10.1177/135581960501000110 · Cited by 2,132 · see citing works
International Journal of Qualitative Methods
(2008) · The SAGE Encyclopedia of Qualitative Research Methods · doi:10.4135/9781412963909.n230 · Cited by 1,501 · see citing works
Mays, N., Pope, C. J., & Popay, J. (2005) · Journal of Health Services Research & Policy · doi:10.1258/1355819054308576 · Cited by 1,384 · see citing works
Qualitative Analysis on Stage: Making the Research Process More Public
Anfara, V. A., Brown, K. M., & Mangione, T. L. (2002) · Educational Researcher · doi:10.3102/0013189x031007028 · Cited by 1,362 · see citing works
Meta‐synthesis method for qualitative research: a literature review
Walsh, D., & Downe, S. (2005) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2005.03380.x · Cited by 1,246 · see citing works
Using meta ethnography to synthesise qualitative research: a worked example
Britten, N., Campbell, R., Pope, C., Donovan, J., Morgan, M., & Pill, R. (2002) · Journal of Health Services Research & Policy · doi:10.1258/135581902320432732 · Cited by 1,110 · see citing works
Patient Adherence to Tuberculosis Treatment: A Systematic Review of Qualitative Research
Munro, S. A., Lewin, S. A., Smith, H. J., Engel, M. E., Fretheim, A., & Volmink, J. (2007) · PLoS Medicine · doi:10.1371/journal.pmed.0040238 · Cited by 1,080 · see citing works
Self-citationCampbell, R., Pound, P., Pope, C., Britten, N., Pill, R., Morgan, M., & Donovan, J. (2003) · Social Science & Medicine · doi:10.1016/s0277-9536(02)00064-3 · Cited by 921 · see citing works
(2003) · Digital Education Resource Archive (University College London) · Cited by 902 · see citing works
Resisting medicines: a synthesis of qualitative studies of medicine taking
Pound, P., Britten, N., Morgan, M., Yardley, L., Pope, C., Daker-White, G., & Campbell, R. (2005) · Social Science & Medicine · doi:10.1016/j.socscimed.2004.11.063 · Cited by 868 · see citing works
The problem of appraising qualitative research
Dixon-Woods, M. (2004) · Quality and Safety in Health Care · doi:10.1136/qshc.2003.008714 · Cited by 653 · see citing works
Directly observed therapy for treating tuberculosis
Karumbi, J., & Garner, P. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003343.pub4 · Cited by 646 · see citing works
Patients' help-seeking experiences and delay in cancer presentation: a qualitative synthesis
Smith, L. K., Pope, C. J., & Botha, J. L. (2005) · The Lancet · doi:10.1016/s0140-6736(05)67030-4 · Cited by 523 · see citing works
Integrating qualitative research with trials in systematic reviews
Thomas, J., Harden, A., Oakley, A., Oliver, S., Sutcliffe, K., Rees, R., Brunton, G., & Kavanagh, J. (2004) · BMJ · doi:10.1136/bmj.328.7446.1010 · Cited by 515 · see citing works
Researching public health: Behind the qualitative-quantitative methodological debate
Baum, F. (1995) · Social Science & Medicine · doi:10.1016/0277-9536(94)e0103-y · Cited by 335 · see citing works
Sandelowski, M., & Barroso, J. V. (2002) · International Journal of Qualitative Methods · doi:10.1177/160940690200100107 · Cited by 331 · see citing works
Harden, A., Garcia, J., Oliver, S., Rees, R., Shepherd, J., Brunton, G., & Oakley, A. (2004) · Journal of Epidemiology and Community Health · doi:10.1136/jech.2003.014829 · Cited by 328 · see citing works
Including qualitative research in systematic reviews: opportunities and problems
Dixon‐Woods, M., Fitzpatrick, R. M., & Roberts, K. (2001) · Journal of Evaluation in Clinical Practice · doi:10.1046/j.1365-2753.2001.00257.x · Cited by 298 · see citing works
Finding qualitative research: an evaluation of search strategies
Shaw, R. L., Booth, A., Sutton, A. J., Miller, T., Smith, J. A., Young, B., Jones, D. R. H., & Dixon‐Woods, M. (2004) · BMC Medical Research Methodology · doi:10.1186/1471-2288-4-5 · Cited by 295 · see citing works
Walter, F. M. (2004) · The Annals of Family Medicine · doi:10.1370/afm.242 · Cited by 283 · see citing works
Krull, W. (1999) · De Gruyter eBooks · doi:10.1515/9783110801026 · Cited by 274 · see citing works
The Challenges of Searching for and Retrieving Qualitative Studies
Barroso, J., Gollop, C. J., Sandelowski, M., Meynell, J., Pearce, P. F., & Collins, L. J. (2003) · Western Journal of Nursing Research · doi:10.1177/0193945902250034 · Cited by 272 · see citing works
Noyes, J., & Popay, J. (2007) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2006.04092.x · Cited by 269 · see citing works
Morse, J. M. (2016) · doi:10.4324/9781315421650 · Cited by 253 · see citing works
Application of systematic review methods to qualitative research: practical issues
Jones, M. L. (2004) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2004.03196.x · Cited by 247 · see citing works
Evaluating and synthesizing qualitative research: the need to develop a distinctive approach
Barbour, R. S., & Barbour, M. (2003) · Journal of Evaluation in Clinical Practice · doi:10.1046/j.1365-2753.2003.00371.x · Cited by 199 · see citing works
Database searches for qualitative research.
Evans, D. J. (2002) · Europe PMC (PubMed Central) · Cited by 179 · see citing works
Directly observed therapy for treating tuberculosis
Volmink, J. A., & Garner, P. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd003343.pub3 · Cited by 177 · see citing works
Self-citationVolmink, J. A., & Garner, P. (1997) · BMJ · doi:10.1136/bmj.315.7120.1403 · Cited by 142 · see citing works
Self-citationQualitative research articles: information for authors and peer reviewers.
Rowan, M. S., & Huston, P. (1997) · Europe PMC (PubMed Central) · Cited by 117 · see citing works
Promoting adherence to tuberculosis treatment
Garner, P. (2007) · Bulletin of the World Health Organization · doi:10.2471/blt.06.035568 · Cited by 97 · see citing works
McEwan, M. J., Espie, C. A., & METCALFE, J. (2003) · Seizure · doi:10.1016/s1059-1311(03)00081-5 · Cited by 93 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Booth A Cochrane or cock-eyed? How should we conduct systematic reviews of qualitative research? Qualitative Evidence-based conference: Taking a critical stance 2001 Coventry University
Cited by
Sorted by citations
Enhancing transparency in reporting the synthesis of qualitative research: ENTREQ
Tong, A., Flemming, K., McInnes, E., Oliver, S., & Craig, J. (2012) · BMC Medical Research Methodology · doi:10.1186/1471-2288-12-181 · Cited by 3,569 · see citing works
Impact of HIV‐related stigma on treatment adherence: systematic review and meta‐synthesis
Katz, I. T., Ryu, A. E., Onuegbu, A. G., Psaros, C., Weiser, S. D., Bangsberg, D. R., & Tsai, A. C. (2013) · Journal of the International AIDS Society · doi:10.7448/ias.16.3.18640 · Cited by 1,126 · see citing works
O’Connor, S., Hanlon, P., O’Donnell, C. A., Garcia, S., Glanville, J., & Mair, F. S. (2016) · BMC Medical Informatics and Decision Making · doi:10.1186/s12911-016-0359-3 · Cited by 636 · see citing works
“Best fit” framework synthesis: refining the method
Carroll, C., Booth, A., Leaviss, J., & Rick, J. (2013) · BMC Medical Research Methodology · doi:10.1186/1471-2288-13-37 · Cited by 649 · see citing works
Improving reporting of meta-ethnography: the eMERGe reporting guidance
France, E. F., Cunningham, M., Ring, N., Uny, I., Duncan, E. A. S., Jepson, R. G., Maxwell, M., Roberts, R. J., Turley, R. L., Booth, A., et al. (2019) · BMC Medical Research Methodology · doi:10.1186/s12874-018-0600-0 · Cited by 469 · see citing works
Self-citationSystematic review approaches for climate change adaptation research
Berrang-Ford, L., Pearce, T., & Ford, J. D. (2015) · Regional Environmental Change · doi:10.1007/s10113-014-0708-7 · Cited by 474 · see citing works
Glenton, C., Colvin, C., Carlsen, B., Swartz, A., Lewin, S., Noyes, J., & Rashidian, A. (2013) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd010414.pub2 · Cited by 454 · see citing works
Self-citationWomen's perceptions and experiences of a traumatic birth: a meta-ethnography
Elmir, R., Schmied, V., Wilkes, L., & Jackson, D. (2010) · Journal of Advanced Nursing · doi:10.1111/j.1365-2648.2010.05391.x · Cited by 432 · see citing works
Odendaal, W. A., Anstey Watkins, J., Leon, N., Goudge, J., Griffiths, F., Tomlinson, M., & Daniels, K. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011942.pub2 · Cited by 289 · see citing works
Mager, U., & Nowak, P. (2012) · Educational Research Review · doi:10.1016/j.edurev.2011.11.001 · Cited by 297 · see citing works
Chiu, T. K. F. (2023) · Interactive Learning Environments · doi:10.1080/10494820.2021.1926289 · Cited by 243 · see citing works
Qualitative Meta-Synthesis of User Experience of Computerised Therapy for Depression and Anxiety
Knowles, S. E., Toms, G., Sanders, C., Bee, P., Lovell, K., Rennick-Egglestone, S., Coyle, D., Kennedy, C. M., Littlewood, E., Kessler, D., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0084323 · Cited by 177 · see citing works
Qualitative synthesis: A guide to conducting a meta-ethnography
Cahill, M., Robinson, K., Pettigrew, J., Galvin, R., & Stanley, M. (2018) · British Journal of Occupational Therapy · doi:10.1177/0308022617745016 · Cited by 168 · see citing works
A methodological systematic review of what’s wrong with meta-ethnography reporting
France, E. F., Ring, N., Thomas, R., Noyes, J., Maxwell, M., & Jepson, R. (2014) · BMC Medical Research Methodology · doi:10.1186/1471-2288-14-119 · Cited by 183 · see citing works
Shiraishi, N., & Reilly, J. (2019) · Social Psychiatry and Psychiatric Epidemiology · doi:10.1007/s00127-018-1617-8 · Cited by 142 · see citing works
Osman, M. A., Schick-Makaroff, K., Thompson, S., Bialy, L., Featherstone, R., Kurzawa, J., Zaidi, D., Okpechi, I., Habib, S., Shojai, S., et al. (2019) · BMJ Global Health · doi:10.1136/bmjgh-2019-001629 · Cited by 108 · see citing works
Origins, methods and advances in qualitative meta-synthesis
Nye, E., Melendez‐Torres, G. J., & Bonell, C. (2016) · Review of Education · doi:10.1002/rev3.3065 · Cited by 118 · see citing works
Hintz, E. A. (2023) · Health Communication · doi:10.1080/10410236.2022.2081046 · Cited by 106 · see citing works
Brunton, L., Bower, P., & Sanders, C. (2015) · PLOS ONE · doi:10.1371/journal.pone.0139561 · Cited by 96 · see citing works
Dennehy, R., Meaney, S., Walsh, K. A., Sinnott, C., Cronin, M., & Arensman, E. (2020) · Aggression and Violent Behavior · doi:10.1016/j.avb.2020.101379 · Cited by 98 · see citing works
A meta-ethnography of patients’ experience of chronic non-malignant musculoskeletal pain
Toye, F., Seers, K., Allcock, N., Briggs, M., Carr, E., Andrews, J., & Barker, K. (2013) · Health Services and Delivery Research · doi:10.3310/hsdr01120 · Cited by 98 · see citing works
Health Information System Implementation: A Qualitative Meta-analysis
Rahimi, B., Vimarlund, V., & Timpka, T. (2009) · Journal of Medical Systems · doi:10.1007/s10916-008-9198-9 · Cited by 82 · see citing works
Galdas, P., Darwin, Z., Kidd, L., Blickem, C., McPherson, K., Hunt, K., Bower, P., Gilbody, S., & Richardson, G. (2014) · BMC Public Health · doi:10.1186/1471-2458-14-1230 · Cited by 76 · see citing works
Nichols, V. P., Ellard, D. R., Griffiths, F. E., Kamal, A., Underwood, M., & Taylor, S. J. C. (2017) · BMJ Open · doi:10.1136/bmjopen-2017-019929 · Cited by 73 · see citing works
Campbell, F., Lawton, J., Rankin, D., Clowes, M., Coates, E., Heller, S., de Zoysa, N., Elliott, J., & Breckenridge, J. P. (2018) · BMC Health Services Research · doi:10.1186/s12913-018-3655-z · Cited by 53 · see citing works
Adolescent social media use and well-being: a systematic review and thematic meta-synthesis
Shankleman, M., Hammond, L., & Jones, F. W. (2021) · Adolescent Research Review · doi:10.1007/s40894-021-00154-5 · Cited by 61 · see citing works
Bootsma, T. I., Schellekens, M. P. J., van Woezik, R. A. M., van der Lee, M. L., & Slatman, J. (2020) · Psycho-Oncology · doi:10.1002/pon.5213 · Cited by 55 · see citing works
Radomski, A. D., Wozney, L., McGrath, P., Huguet, A., Hartling, L., Dyson, M. P., Bennett, K., & Newton, A. S. (2019) · Journal of Medical Internet Research · doi:10.2196/11128 · Cited by 40 · see citing works
Duncan, T. K., Sebar, B., & Lee, J. (2015) · Advances in Eating Disorders · doi:10.1080/21662630.2014.978804 · Cited by 48 · see citing works
Heys, S., Downe, S., & Thomson, G. (2021) · Midwifery · doi:10.1016/j.midw.2021.103123 · Cited by 42 · see citing works
Soundy, A., Smith, B., Dawes, H., Pall, H., Gimbrere, K., & Ramsay, J. (2013) · Health Psychology Review · doi:10.1080/17437199.2011.568856 · Cited by 42 · see citing works
Melendez‐Torres, G. J., Grant, S., & Bonell, C. (2015) · Research Synthesis Methods · doi:10.1002/jrsm.1161 · Cited by 39 · see citing works
How do women's partners view perinatal mental health services? A qualitative meta‐synthesis
Lever Taylor, B., Billings, J., Morant, N., & Johnson, S. (2018) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2133 · Cited by 36 · see citing works
Corcoran, S., & Kelly, C. (2023) · Journal of Research in Special Educational Needs · doi:10.1111/1471-3802.12577 · Cited by 33 · see citing works
Rose, K., O'Malley, C., Eskandari, F., Lake, A. A., Brown, L., & Ells, L. J. (2021) · Obesity Reviews · doi:10.1111/obr.13186 · Cited by 30 · see citing works
Little, H., Tickle, A., & das Nair, R. (2018) · Psychology and Psychotherapy Theory Research and Practice · doi:10.1111/papt.12156 · Cited by 28 · see citing works
Pickles, K., Eassey, D., Reddel, H. K., Locock, L., Kirkpatrick, S., & Smith, L. (2018) · Health Expectations · doi:10.1111/hex.12605 · Cited by 28 · see citing works
Saragosa, M., Jeffs, L., Okrainec, K., & Kuluski, K. (2022) · Dementia · doi:10.1177/14713012211031779 · Cited by 21 · see citing works
Juel, A., Berring, L. L., Hybholt, L., Erlangsen, A., Larsen, E. R., & Buus, N. (2021) · International Journal of Nursing Studies · doi:10.1016/j.ijnurstu.2020.103793 · Cited by 20 · see citing works
Joseph, G. (2024) · American Journal of Community Psychology · doi:10.1002/ajcp.12670 · Cited by 19 · see citing works
Partners' Experience of Informal Caregiving for Patients With Heart Failure: A Meta-ethnography
Wang, Z., & Tocchi, C. (2023) · Journal of Cardiovascular Nursing · doi:10.1097/jcn.0000000000000903 · Cited by 18 · see citing works
Williams, K., Hartley, S., Langer, S., Manandhar‐Richardson, M., Sinha, M., & Taylor, P. (2022) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2773 · Cited by 13 · see citing works
Nurunnaher, Xiao, L., Gordon, S., & Ahmad, M. (2023) · Aging & Mental Health · doi:10.1080/13607863.2023.2222078 · Cited by 11 · see citing works
- Authors
- Atkins, S., Lewin, S., Smith, H., Engel, M., Fretheim, A., & Volmink, J.
- Affiliations
- South African Medical Research Council (ZA)
- Liverpool School of Tropical Medicine (GB)
- University of Cape Town (ZA)
- Nasjonalt Kunnskapssenter for Helsetjenesten (NO)
- Corresponding author
- Atkins, Salla
- Venue
- BMC Medical Research Methodology
- Published
- 2008-04-16
- Volume
- 8
- Issue
- 1
- Pages
- 21-21
- ISSN
- 1471-2288 (ISSN-L)
- PMC
- PMC2374791
- OpenAlex
- W2022496169
- Cited by
- 981
- References
- 38
- Citations by year
- 2026: 23 · 2025: 53 · 2024: 79 · 2023: 81 · 2022: 83 · 2021: 87 · 2020: 94 · 2019: 74 · 2018: 65 · 2017: 48 · 2016: 49 · 2015: 64 · 2014: 48 · 2013: 49 · 2012: 28
- FWCI
- 20.79
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- BMC Medical Research Methodology (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (publishedVersion)
- LSTM Online Archive (Liverpool School of Tropical Medicine) (acceptedVersion)
- LSHTM Research Online (London School of Hygiene and Tropical Medicine) (acceptedVersion)
- BIBSYS Brage (BIBSYS (Norway)) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- NORA - Norwegian Open Research Archives (submittedVersion, other-oa)
- Open University of Cape Town (University of Cape Town) (submittedVersion, cc-by)
- SUNScholar (Stellenbosch University) (submittedVersion)
- Funders
- London School of Hygiene and Tropical Medicine
- Medical Research Council
- Topics
- Social Sciences › Decision Sciences › Statistics, Probability and Uncertainty › Meta-analysis and systematic reviews
- Social Sciences › Education › Qualitative Research Methods and Applications
- Social Sciences › Sociology and Political Science › Delphi Technique in Research
- Keywords
- meta-ethnography, qualitative evidence synthesis, tuberculosis treatment adherence, methodological issues, study quality assessment, research question formulation, health care research, epistemology of qualitative research
- MeSH terms
- Anthropology, Cultural, Humans, Health Knowledge, Attitudes, Practice, Patient Compliance, Quality Control, Tuberculosis, Meta-Analysis as Topic, Qualitative Research
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review