Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

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Modeling Development and Disease with Organoids

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Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

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Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

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Diffusion pseudotime robustly reconstructs lineage branching

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Single-cell messenger RNA sequencing reveals rare intestinal cell types

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Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors

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A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis

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In Vitro Expansion of Human Gastric Epithelial Stem Cells and Their Responses to Bacterial Infection

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Visualization and targeting of LGR5+ human colon cancer stem cells

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<i>destiny</i> : diffusion maps for large-scale single-cell data in R

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Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

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Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

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Efficient genetic engineering of human intestinal organoids using electroporation

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Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells

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Growth Factor FGF2 Cooperates with Interleukin-17 to Repair Intestinal Epithelial Damage

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The Ets transcription factor Spi-B is essential for the differentiation of intestinal microfold cells

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Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin

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FGF-2 enhances intestinal stem cell survival and its expression is induced after radiation injury

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Impact of Diet-Induced Obesity on Intestinal Stem Cells: Hyperproliferation but Impaired Intrinsic Function That Requires Insulin/IGF1

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p38 kinase regulates epidermal growth factor receptor downregulation and cellular migration

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Distinct Effects of p38α Deletion in Myeloid Lineage and Gut Epithelia in Mouse Models of Inflammatory Bowel Disease

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Canonical Wnt signals combined with suppressed TGFβ/BMP pathways promote renewal of the native human colonic epithelium

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Ghrelin and Motilin Are Cosecreted from a Prominent Endocrine Cell Population in the Small Intestine

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‘Cold shock’ increases the frequency of homology directed repair gene editing in induced pluripotent stem cells

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IGF1 stimulates crypt expansion via differential activation of 2 intestinal stem cell populations

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Gastrointestinal Fibroblasts Have Specialized, Diverse Transcriptional Phenotypes: A Comprehensive Gene Expression Analysis of Human Fibroblasts

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Human organoids: model systems for human biology and medicine

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Establishment of patient-derived cancer organoids for drug-screening applications

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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

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Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening

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Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

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Organoid Models of Tumor Immunology

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Modeling neoplastic disease with spheroids and organoids

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Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells

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Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches

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An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping

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CRISPR-Cas Tools and Their Application in Genetic Engineering of Human Stem Cells and Organoids

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Applications of organoids for cancer biology and precision medicine

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Mapping Development of the Human Intestinal Niche at Single-Cell Resolution

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Microengineered Multi‐Organoid System from hiPSCs to Recapitulate Human Liver‐Islet Axis in Normal and Type 2 Diabetes

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Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

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In Vitro three-dimensional (3D) cell culture tools for spheroid and organoid models

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An organoid-based organ-repurposing approach to treat short bowel syndrome

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Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases

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Organoid cultures for cancer modeling

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Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

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Charting human development using a multi-endodermal organ atlas and organoid models

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Gut organoids: mini-tissues in culture to study intestinal physiology and disease

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Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

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Game changers in science and technology - now and beyond

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Developments and Opportunities for 3D Bioprinted Organoids

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Organoid systems to study the human female reproductive tract and pregnancy

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Organoids are not organs: Sources of variation and misinformation in organoid biology

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The drug-induced phenotypic landscape of colorectal cancer organoids

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Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk

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Single‐cell analyses reveal SARS‐CoV‐2 interference with intrinsic immune response in the human gut

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Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids

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