Human Intestinal Organoids Maintain Self-Renewal Capacity and Cellular Diversity in Niche-Inspired Culture Condition

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Modeling Development and Disease with Organoids

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In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

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Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

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Human organoids: model systems for human biology and medicine

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Establishment of patient-derived cancer organoids for drug-screening applications

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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

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Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening

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Automated microfluidic platform for dynamic and combinatorial drug screening of tumor organoids

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Organoid Models of Tumor Immunology

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Somatic inflammatory gene mutations in human ulcerative colitis epithelium

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Fast and efficient generation of knock-in human organoids using homology-independent CRISPR–Cas9 precision genome editing

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Three-dimensional human alveolar stem cell culture models reveal infection response to SARS-CoV-2

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Modeling neoplastic disease with spheroids and organoids

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Establishment and Culture of Human Intestinal Organoids Derived from Adult Stem Cells

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Intestinal Permeability and Drug Absorption: Predictive Experimental, Computational and In Vivo Approaches

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Mechanisms of mucosal healing: treating inflammatory bowel disease without immunosuppression?

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Symbiotic polyamine metabolism regulates epithelial proliferation and macrophage differentiation in the colon

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Synthetic dynamic hydrogels promote degradation-independent in vitro organogenesis

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A Proximal-to-Distal Survey of Healthy Adult Human Small Intestine and Colon Epithelium by Single-Cell Transcriptomics

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An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping

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CRISPR-Cas Tools and Their Application in Genetic Engineering of Human Stem Cells and Organoids

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Applications of organoids for cancer biology and precision medicine

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Mapping Development of the Human Intestinal Niche at Single-Cell Resolution

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Microengineered Multi‐Organoid System from hiPSCs to Recapitulate Human Liver‐Islet Axis in Normal and Type 2 Diabetes

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Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

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In Vitro three-dimensional (3D) cell culture tools for spheroid and organoid models

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Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids

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An organoid-based organ-repurposing approach to treat short bowel syndrome

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Somatic cell-derived organoids as prototypes of human epithelial tissues and diseases

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Organoid cultures for cancer modeling

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Human-specific genetics: new tools to explore the molecular and cellular basis of human evolution

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Charting human development using a multi-endodermal organ atlas and organoid models

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Gut organoids: mini-tissues in culture to study intestinal physiology and disease

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Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

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Game changers in science and technology - now and beyond

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Developments and Opportunities for 3D Bioprinted Organoids

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Differentiation of Human Intestinal Organoids with Endogenous Vascular Endothelial Cells

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Organoid systems to study the human female reproductive tract and pregnancy

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BMP gradient along the intestinal villus axis controls zonated enterocyte and goblet cell states

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Organoids are not organs: Sources of variation and misinformation in organoid biology

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The drug-induced phenotypic landscape of colorectal cancer organoids

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Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk

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Single‐cell analyses reveal SARS‐CoV‐2 interference with intrinsic immune response in the human gut

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Wnt Signaling in 3D: Recent Advances in the Applications of Intestinal Organoids

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Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis

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Bioengineered human colon organoids with in vivo-like cellular complexity and function

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ILC1 drive intestinal epithelial and matrix remodelling

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Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice

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Gastric organoids—an in vitro model system for the study of gastric development and road to personalized medicine

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Human Intestinal Organoids: Promise and Challenge

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Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

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Development of a Scalable Coculture System for Gut Anaerobes and Human Colon Epithelium

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Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury

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Organoids for Functional Precision Medicine in Advanced Pancreatic Cancer

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Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands

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Current methods for studying metastatic potential of tumor cells

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IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment

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Bacterial biofilms in the human body: prevalence and impacts on health and disease

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Organoid-based Models to Study the Role of Host-microbiota Interactions in IBD

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Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration

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Organoid Models for Precision Cancer Immunotherapy

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Labeling and Characterization of Human GLP-1-Secreting L-cells in Primary Ileal Organoid Culture

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Salmonella effector driven invasion of the gut epithelium: breaking in and setting the house on fire

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Intestinal organ chips for disease modelling and personalized medicine

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Middle-out methods for spatiotemporal tissue engineering of organoids

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Organoid screening reveals epigenetic vulnerabilities in human colorectal cancer

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Newly developed 3D in vitro models to study tumor–immune interaction

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PNPLA3 as a therapeutic target for fatty liver disease: the evidence to date

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Human Microphysiological Models of Intestinal Tissue and Gut Microbiome

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What Is an L-Cell and How Do We Study the Secretory Mechanisms of the L-Cell?

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Patient‐derived organoids for personalized gallbladder cancer modelling and drug screening

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Applications of human organoids in the personalized treatment for digestive diseases

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Genotype-phenotype mapping of a patient-derived lung cancer organoid biobank identifies NKX2-1-defined Wnt dependency in lung adenocarcinoma

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Chromosome Engineering of Human Colon-Derived Organoids to Develop a Model of Traditional Serrated Adenoma

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Multifunctional microfluidic chip for cancer diagnosis and treatment

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Multiscale Mechanobiology in Brain Physiology and Diseases

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Arachidonic Acid Promotes Intestinal Regeneration by Activating WNT Signaling

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