Modeling Down Syndrome with Patient iPSCs Reveals Cellular and Migration Deficits of GABAergic Neurons

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Transchromosomic cell model of Down syndrome shows aberrant migration, adhesion and proteome response to extracellular matrix

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Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model

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Human iPSC-derived Down syndrome astrocytes display genome-wide perturbations in gene expression, an altered adhesion profile, and increased cellular dynamics

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Neurodevelopment in Down syndrome: Concordance in humans and models

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Integrative analysis identifies key molecular signatures underlying neurodevelopmental deficits in fragile X syndrome.

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Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

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Bioengineering tissue morphogenesis and function in human neural organoids

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Meta-analysis of metabolites involved in bioenergetic pathways reveals a pseudohypoxic state in Down syndrome

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Neuronal Cytoskeleton in Intellectual Disability: From Systems Biology and Modeling to Therapeutic Opportunities

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Altered patterning of trisomy 21 interneuron progenitors

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Di-(2-ethylhexyl) phthalate exposure impairs cortical development in hESC-derived cerebral organoids

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Astrocytes in Down Syndrome Across the Lifespan

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Dose imbalance of DYRK1A kinase causes systemic progeroid status in Down syndrome by increasing the un-repaired DNA damage and reducing LaminB1 levels

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APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer’s pathology in trisomy 21 neurons

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Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling

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Translational validity and implications of pharmacotherapies in preclinical models of Down syndrome

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Abnormal mitochondria in Down syndrome iPSC-derived GABAergic interneurons and organoids

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Choroid plexus defects in Down syndrome brain organoids enhance neurotropism of SARS-CoV-2

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Consequences of trisomy 21 for brain development in Down syndrome

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The innate immune system stimulating cytokine GM-CSF improves learning/memory and interneuron and astrocyte brain pathology in Dp16 Down syndrome mice and improves learning/memory in wild-type mice

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Integrative multi-omic analysis reveals conserved cell-projection deficits in human Down syndrome brains

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Neuroanatomical alterations in higher-order thalamic nuclei of fetuses with Down syndrome

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Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models

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Asynchronous excitatory neuron development in an isogenic cortical spheroid model of Down syndrome

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Challenges and Opportunities for Translation of Therapies to Improve Cognition in Down Syndrome

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Focusing on cellular biomarkers: The endo-lysosomal pathway in Down syndrome.

Botté, A., & Potier, M. (2020) · Progress in Brain Research · doi:10.1016/bs.pbr.2019.10.002 · Cited by 20 · see citing works

Neurogenesis and neuronal differentiation in the postnatal frontal cortex in Down syndrome

Utagawa, E. C., Moreno, D. G., Schafernak, K. T., Arva, N. C., Malek‐Ahmadi, M. H., Mufson, E. J., & Perez, S. E. (2022) · Acta Neuropathologica Communications · doi:10.1186/s40478-022-01385-w · Cited by 24 · see citing works

Distinct patterns of GABAergic interneuron pathology in autism are associated with intellectual impairment and stereotypic behaviors

Dufour, B. D., McBride, E., Bartley, T., Juárez, P., & Martínez‐Cerdeño, V. (2023) · Autism · doi:10.1177/13623613231154053 · Cited by 22 · see citing works

Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration

Mitsogiannis, M. D., Pancho, A., Aerts, T., Sachse, S., Vanlaer, R., Noterdaeme, L., Schmucker, D., & Seuntjens, E. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.624181 · Cited by 20 · see citing works

Modeling Down syndrome in cells: From stem cells to organoids

Gough, G., O’Brien, N. L., Alić, I., Goh, P. A., Yeap, Y. J., Groet, J., Nižetić, D., & Murray, A. (2019) · Progress in brain research · doi:10.1016/bs.pbr.2019.10.003 · Cited by 20 · see citing works

Dysregulation of mTOR signaling mediates common neurite and migration defects in both idiopathic and 16p11.2 deletion autism neural precursor cells

Prem, S., Dev, B., Peng, C., Mehta, M., Alibutud, R., Connacher, R., Thomas, M. S., Zhou, X., Matteson, P. G., Xing, J., et al. (2024) · eLife · doi:10.7554/elife.82809 · Cited by 19 · see citing works

Transition from Animal-Based to Human Induced Pluripotent Stem Cells (iPSCs)-Based Models of Neurodevelopmental Disorders: Opportunities and Challenges

Guerreiro, S. R., & Maciel, P. (2023) · Cells · doi:10.3390/cells12040538 · Cited by 20 · see citing works

Cell Transdifferentiation and Reprogramming in Disease Modeling: Insights into the Neuronal and Cardiac Disease Models and Current Translational Strategies

Kalra, R. S., Dhanjal, J. K., Das, M., Singh, B., & Naithani, R. (2021) · Cells · doi:10.3390/cells10102558 · Cited by 17 · see citing works

Cell models for Down syndrome-Alzheimer’s disease research

Wu, Y., West, N. R., Bhattacharyya, A., & Wiseman, F. K. (2022) · Neuronal Signaling · doi:10.1042/ns20210054 · Cited by 17 · see citing works

Human‐Derived Induced GABAergic Progenitor Cells Improve Cognitive Function in Mice and Inhibit Astrocyte Activation with Anti‐Inflammatory Exosomes

Chen, C., Lan, Z., Tang, X., Chen, W., Zhou, X. W., Su, H., Su, R., Chen, Z., Chen, H., Guo, Y., et al. (2024) · Annals of Neurology · doi:10.1002/ana.27001 · Cited by 16 · see citing works

A Tale of Two Chimeras: Applying the Six Principles to Human Brain Organoid Xenotransplantation

Barnhart, A. J., & Dierickx, K. (2023) · Cambridge Quarterly of Healthcare Ethics · doi:10.1017/s0963180123000051 · Cited by 16 · see citing works

Transcriptional consequences of trisomy 21 on neural induction

Martinez, J. L., Piciw, J. G., Crockett, M., Sorci, I. A., Makwana, N., Sirois, C. L., Giffin-Rao, Y., & Bhattacharyya, A. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1341141 · Cited by 15 · see citing works

Chimeric brain models: Unlocking insights into human neural development, aging, diseases, and cell therapies

Papetti, A. V., Jin, M., Ma, Z., Stillitano, A. C., & Jiang, P. (2025) · Neuron · doi:10.1016/j.neuron.2025.03.036 · Cited by 15 · see citing works

Prenatal and Postnatal Pharmacotherapy in Down Syndrome: The Search to Prevent or Ameliorate Neurodevelopmental and Neurodegenerative Disorders

Bartesaghi, R., Vicari, S., & Mobley, W. C. (2022) · The Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-041521-103641 · Cited by 15 · see citing works

Large-scale organoid study suggests effects of trisomy 21 on early fetal neurodevelopment are more subtle than variability between isogenic lines and experiments

Czerminski, J. T., King, O. D., & Lawrence, J. B. (2023) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.972201 · Cited by 15 · see citing works

From neurodevelopment to neurodegeneration: utilizing human stem cell models to gain insight into Down syndrome

Watson, L. A., & Meharena, H. S. (2023) · Frontiers in Genetics · doi:10.3389/fgene.2023.1198129 · Cited by 13 · see citing works

Diet-induced weight loss in obese/diabetic mice normalizes glucose metabolism and promotes functional recovery after stroke

Karampatsi, D., Zabala, A., Wilhelmsson, U., Dekens, D. W., Vercalsteren, E., Larsson, M., Nyström, T., Pekny, M., Patrone, C., & Darsalia, V. (2021) · Cardiovascular Diabetology · doi:10.1186/s12933-021-01426-z · Cited by 13 · see citing works

Neurodevelopmental wiring deficits in the Ts65Dn mouse model of Down syndrome

Jain, S., Watts, C. A., Chung, W. C. J., & Welshhans, K. (2019) · Neuroscience Letters · doi:10.1016/j.neulet.2019.134569 · Cited by 13 · see citing works

Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain

Farley, S. J., Grishok, A., & Zeldich, E. (2022) · Epigenetics & Chromatin · doi:10.1186/s13072-022-00471-6 · Cited by 13 · see citing works

Segmentation of the foveal and parafoveal retinal architecture using handheld spectral-domain optical coherence tomography in children with Down syndrome

Nicholson, R., Osborne, D., Fairhead, L., Beed, L., Hill, C. M., & Lee, H. (2022) · Eye · doi:10.1038/s41433-021-01883-6 · Cited by 10 · see citing works

Single-Nucleus Profiling Identifies Accelerated Oligodendrocyte Precursor Cell Senescence in a Mouse Model of Down Syndrome

Rusu, B., Kukreja, B., Wu, T., Dan, S. J., Feng, M.-Y., & Kalish, B. (2023) · eNeuro · doi:10.1523/eneuro.0147-23.2023 · Cited by 2 · see citing works

Human-mouse chimeric brain models constructed from iPSC-derived brain cells: Applications and challenges

Zhao, Y., Liu, P., Wang, Y., Ma, Y., Guo, W., & Shi, C. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114848 · Cited by 9 · see citing works

Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment

Dong, X., Yang, L., Liu, K., Ji, X., Tang, C., Li, W., Ma, L., Mei, Y., Peng, T., Feng, B., et al. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108802 · Cited by 8 · see citing works

Transcriptome and metabolome analysis of crGART, a novel cell model of de novo purine synthesis deficiency: Alterations in CD36 expression and activity

Mazzarino, R. C., Barešová, V., Zikánová, M., Duval, N., Wilkinson, T. G., Patterson, D., & Vacano, G. N. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247227 · Cited by 8 · see citing works

Migration deficits of the neural crest caused by CXADR triplication in a human Down syndrome stem cell model

Liu, H., Huang, S., Wang, W., Wang, H., Huang, W., Zhai, Z., Wang, D., Fan, Y., Sun, J., Li, D., et al. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-05481-6 · Cited by 8 · see citing works

Dosage Counts: Correcting Trisomy-21-Related Phenotypes in Human Organoids and Xenografts

Manley, W. F., & Anderson, S. A. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.05.009 · Cited by 7 · see citing works

Analysis of genotype effects and inter-individual variability in iPSC-derived trisomy 21 neural progenitor cells.

Lee, S. E., Baxter, L. L., Duran, M. I., Morris, S. D., Mosley, I. A., Fuentes, K. A., Pennings, J., Guedj, F., & Bianchi, D. W. (2024) · Human Molecular Genetics · doi:10.1093/hmg/ddae160 · Cited by 3 · see citing works

In and out: Benchmarking in vitro, in vivo, ex vivo, and xenografting approaches for an integrative brain disease modeling pipeline

Pereira, M. F., Shyti, R., & Testa, G. (2024) · Stem Cell Reports · doi:10.1016/j.stemcr.2024.05.004 · Cited by 6 · see citing works

Integrative Analysis Extracts a Core ceRNA Network of the Fetal Hippocampus With Down Syndrome

Wang, S., Tang, X., Qin, L., Shi, W., Bian, S., Wang, Z., Wang, Q., Wang, X., Gu, J., Hao, B., et al. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.565955 · Cited by 6 · see citing works

Emerging Human Pluripotent Stem Cell-Based Human–Animal Brain Chimeras for Advancing Disease Modeling and Cell Therapy for Neurological Disorders

Ji, Y., McLean, J. L., & Xu, R. (2024) · Neuroscience Bulletin · doi:10.1007/s12264-024-01189-z · Cited by 6 · see citing works

The Study of Alternative Splicing Events in Human Induced Pluripotent Stem Cells From a Down's Syndrome Patient

Wang, Y., Li, Z., Yang, G., Cai, L., Yang, F., Zhang, Y., Zeng, Y., Ma, Q., & Zeng, F. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.661381 · Cited by 6 · see citing works

Early chronic fasudil treatment rescues hippocampal alterations in the Ts65Dn model for down syndrome

López‐Hidalgo, R., Ballestín, R., Lorenzo, L., Sánchez-Martí, S., Blasco‐Ibáñez, J. M., Crespo, C., Nácher, J., & Varea, E. (2024) · Neurochemistry International · doi:10.1016/j.neuint.2024.105679 · Cited by 4 · see citing works

iPSCs-Derived Neurons and Brain Organoids from Patients

Zhu, W., Xu, L., Li, X., Hu, H., Lou, S.-N., & Liu, Y. (2023) · Handbook of experimental pharmacology · doi:10.1007/164_2023_657 · Cited by 5 · see citing works

Stem cell-based therapeutic strategies for down syndrome and Alzheimer’s disease

Hamadelseed, O., & Skutella, T. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04556-3 · Cited by 5 · see citing works

Identification of Sodium Transients Through NaV1.5 Channels as Regulators of Differentiation in Immortalized Dorsal Root Ganglia Neurons

Martínez, A. L., Brea, J. M., Domínguez, E., Varela, M. J., Allegue, C., Cruz, R., Monroy, X., Merlos, M., Burgueño, J., Carracedo, Á., et al. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.816325 · Cited by 5 · see citing works

Cognitive impairments in a Down syndrome model with abnormal hippocampal and prefrontal dynamics and cytoarchitecture

Muza, P. M., Bush, D., Pérez-González, M., Zouhair, I., Cleverley, K., Sopeña, M. L., Aoidi, R., West, S. J., Good, M. A., Tybulewicz, V. L. J., et al. (2023) · iScience · doi:10.1016/j.isci.2023.106073 · Cited by 5 · see citing works

Pro-inflammatory Cytokine GM-CSF Improves Learning/Memory and Brain Pathology in Dp16 Down Syndrome Mice and Improves Learning/Memory in Wild-Type MicePreprint

Ahmed, M. M., Wang, A. C.-J., Elos, M. T., Chial, H. J., Sillau, S. H., Solano, D., Coughlan, C. M., Aghili, L., Anton, P., Markham, N., et al. (2021) · bioRxiv · doi:10.1101/2021.07.04.451073 · Cited by 2 · see citing works

Trisomy 21-driven metabolite alterations are linked to cellular injuries in Down syndrome

Liu, J., Chen, S., Huang, G., Wen, P., Zhou, X., & Wu, Y. (2024) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-024-05127-0 · Cited by 4 · see citing works

Total cell N-glycosylation is altered during differentiation of induced pluripotent stem cells to neural stem cells and is disturbed by trisomy 21

Cindrić, A., Vučković, F., Murray, A., Klarić, T., Alić, I., Petrović, D. J., Krištić, J., Nižetić, D., & Lauc, G. (2024) · BBA Advances · doi:10.1016/j.bbadva.2024.100137 · Cited by 4 · see citing works

Elucidation of the Pathogenesis of Autoinflammatory Diseases Using iPS Cells

Saito, M. K. (2021) · Children · doi:10.3390/children8020094 · Cited by 4 · see citing works

Mid-gestational cell-type-specific transcriptomic signatures in the prefrontal and superior temporal cortex in Down syndrome

Niu, R.-Z., Xue, L.-L., Tian, X.-H., Huangfu, L.-R., Chen, L., Zhai, C.-Y., Wang, S.-F., Zhao, Y.-Y., Gan, Z.-J., Qin, H.-Y., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-66109-9 · Cited by 4 · see citing works

Exploring perspectives of Dscam for cognitive deficits: a review of multifunction for regulating neural wiring in homeostasis

Xiong, Y., Li, L., & Zhang, X. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1575348 · Cited by 3 · see citing works

Cellularity Defects Are Not Ubiquitous in the Brains of Fetuses With Down Syndrome

Emili, M., Stagni, F., Bonasoni, M., Guidi, S., & Bartesaghi, R. (2024) · Developmental Neurobiology · doi:10.1002/dneu.22953 · Cited by 3 · see citing works

Interneuron migration impairment and brain region-specific DNA damage response following irradiation during early neurogenesis in mice

Berden, L., Rajan, N., Mfossa, A. C. M., Bie, I. D., Etlioglu, E., Benotmane, M. A., Verslegers, M., Aourz, N., Smolders, I. J., Rigo, J., et al. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05643-7 · Cited by 3 · see citing works

Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis

Hinckelmann, M.-V., Dubos, A., Artot, V., Rudolf, G., Nguyen, T. L., Tilly, P., Nalesso, V., Moreno, M. D. M. M., Birling, M., Godin, J. D., et al. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03109-7 · Cited by 4 · see citing works

Electrospinning-constructed polysaccharide-based multilayer nanofiber composite membrane for bridging hemostasis and tissue repair

Tan, R., Wen, Z., He, X., Lu, B., Hu, E., Xie, R., Lan, G., Guo, C., Cheng, C., Cheng, B., et al. (2026) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2026.125355 · Cited by 2 · see citing works

Pharmacological Inhibition of p-21 Activated Kinase (PAK) Restores Impaired Neurite Outgrowth and Remodeling in a Cellular Model of Down Syndrome

Barraza, N., Pérez-Núñez, R., Gaete‐Ramírez, B., Barrios-Garrido, A., Arriagada, C., Poksay, K. S., John, V., Barnier, J., Cárdenas, A. M., & Caviedes, P. A. (2023) · Neurotoxicity Research · doi:10.1007/s12640-023-00638-3 · Cited by 2 · see citing works

A Dive Into Cerebellar Dysfunction, Motor Deficits and GABAergic Signaling in Down Syndrome

Feely, S., Rodriguez, M. R., Shannon, A., Young, S., Rosales, J. P., & Kaur, G. (2025) · Cureus · doi:10.7759/cureus.79623 · Cited by 2 · see citing works

Neuronal activity modulates the expression of secretagogin, a Ca2+ sensor protein, during mammalian forebrain development

Hanics, J., Tretiakov, E. O., Romanov, R. A., Gáspárdy, A., Hevesi, Z., Schnell, R., Harkany, T., & Alpár, A. (2025) · Acta Physiologica · doi:10.1111/apha.70031 · Cited by 2 · see citing works

Modeling Down syndrome neurodevelopment with isogenic cerebral organoidsPreprint

Czerminski, J. T., King, O. D., & Lawrence, J. B. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.05.25.493459 · Cited by 2 · see citing works

Interneuron migration defects during corticogenesis contribute to Dyrk1a haploinsufficiency syndrome pathogenesis via actomyosin dynamics deregulationsPreprint

Hinckelmann, M.-V., Dubos, A., Artot, V., Rudolf, G., Nguyen, T. L., Tilly, P., Nalesso, V., Moreno, M. D. M. M., Birling, M., Godin, J. D., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.11.09.566424 · Cited by 2 · see citing works

Generation of an induced pluripotent stem cell line (NCHi010-A) from a 6-year-old female with Down syndrome and without congenital heart disease

Yu, Y., Alonzo, M., Ye, S., Fang, A., Manickam, K., Garg, V., & Zhao, M. (2023) · Stem Cell Research · doi:10.1016/j.scr.2023.103155 · Cited by 1 · see citing works

REST deficiency and neurogenic-to-gliogenic shift in down syndrome human cerebral organoids

Huang, T., Lim, C.-T., Li, W., Fakurazi, S., Mason, J. O., Cheah, P.-S., Li, Y., & Ling, K. (2026) · Molecular Brain · doi:10.1186/s13041-026-01313-2 · Cited by 1 · see citing works

Abnormal neuronal and synaptic morphology in Down syndrome brains reproduces in human isogenic cellular models

Plećaš, A., Gough, G., Grčević, D., Jackowiak, H., Skieresz‐Szewczyk, K., Horaček, M., Šimunić, I., Krsnik, Ž., Mitrečić, D., Murray, A., et al. (2026) · Cell Death and Disease · doi:10.1038/s41419-026-08956-y · Cited by 1 · see citing works

Joint modeling of an outcome variable and integrated omics datasets using GLM-PO2PLS

Gu, Z., Uh, H., Houwing‐Duistermaat, J. J., & el Bouhaddani, S. (2024) · Journal of Applied Statistics · doi:10.1080/02664763.2024.2313458 · Cited by 1 · see citing works

Modeling Down Syndrome Neurodevelopment with Dosage Compensation

Czerminski, J. T. (2019) · eScholarship@UMassChan · doi:10.13028/j7xf-1q21 · Cited by 1 · see citing works

Restoring DSCAM expression rescues neuronal morphology and axon guidance deficits in Down syndromePreprint

Agrawal, M., Kirkise, N., Rygel, K., Sahoo, P. K., Vincent, C. J., Joyner, D., Aguilar-Alvarez, R., Philip, T. R., Dhillon, P. S., Patel, J., et al. (2025) · bioRxiv · doi:10.1101/2025.07.25.666804 · Cited by 1 · see citing works

miR155 triplicated in Down syndrome regulates hippocampal GABAergic neurogenesis in Alzheimer’s diseasePreprint

Zhu, X., Haure‐Mirande, J., Bicak, M., Dong, P., Kruglikov, I., Al-subaie, A., Fossati, V., Noggle, S., Gandy, S., & Ehrlich, M. E. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.09.28.679053 · Cited by 1 · see citing works

Gene-dosage imbalance and altered neurogenesis in Down syndrome

Ganguly, B. B. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-90456-8.00006-5

Agonist-Induced Functional Analysis and Cell Sorting (aiFACS) to Select and Characterize Interneurons During Brain Development

Cazareth, J., Jarjat, M., Brau, F., Bardoni, B., & Maurin, T. (2022) · Neuromethods · doi:10.1007/978-1-0716-2569-9_4

Realizing the potential of exploiting human IPSCs and their derivatives in research of Down syndrome

Wang, Y., Ni, J., LIU, Y., Liao, D.-Y., Zhou, Q., Ji, X., NIU, G., & Ni, Y. (2023) · Biocell · doi:10.32604/biocell.2023.043781

Human Models of Down Syndrome

Jandy, M., Hu, H., Liu, Y., & Bhattacharyya, A. (2025) · Springer eBooks · doi:10.1007/978-3-031-78611-2_7

A Critical Period in Cortical Interneuron Neurogenesis in Down Syndrome Revealed by Human Neural Progenitor Cells

Bhattacharyya, A., McMillan, E., Chen, S. I., Wallace, K., & Svendsen, C. N. (2009) · Developmental Neuroscience · doi:10.1159/000236899 · Cited by 79 · see citing works

Altered patterning of trisomy 21 interneuron progenitors

Giffin-Rao, Y., Sheng, J., Strand, B., Xu, K., Huang, L., Medo, M., Risgaard, K. A., Dantinne, S., Mohan, S., Keshan, A., et al. (2022) · Stem Cell Reports · doi:10.1016/j.stemcr.2022.05.001 · Cited by 38 · see citing works

LHX6 is essential for the migration of human pluripotent stem cell-derived GABAergic interneurons

Yuan, F., Fang, K.-H., Hong, Y., Xu, S., Xu, M., Pan, Y., & Liu, Y. (2020) · Protein & Cell · doi:10.1007/s13238-019-00686-6 · Cited by 16 · see citing works

Differential gene expression in migrating cortical interneurons during mouse forebrain development

Faux, C. H., Rakić, S., Andrews, W. D., Yanagawa, Y., Obata, K., & Parnavelas, J. G. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22271 · Cited by 41 · see citing works

OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome

Xu, R., Brawner, A. T., Li, S., Liu, J.-J., Kim, H., Xue, H., Pang, Z. P., Kim, W.-Y., Hart, R. P., Liu, Y., et al. (2019) · Cell Stem Cell · doi:10.1016/j.stem.2019.04.014 · Cited by 193 · see citing works