Bandage-like wearable flexible microfluidic recombinase polymerase amplification sensor for the rapid visual detection of nucleic acids
Abstract
With the development of flexible advanced materials and microfluidic technology, wearable biosensors provide a new strategy for the continuous monitoring of health. In this study, a novel bandage-like wearable flexible microfluidic recombinase polymerase amplification (RPA) sensor was constructed for the rapid and visual detection of nucleic acids. This wearable sensor is triggered by human body heat (30°C-37 °C) and allows for visual nucleic acid (a conserved nucleic acid fragments of zika virus) detection within 10 min. The sensor displays good sensitivity and selectivity, with a detection limit of 10 copies/μL. The wearable sensor has exhibited well-defined accuracy when applied to testing clinical serum samples. In addition, the wearable RPA sensor was proved to be feasible by human trials under different daily activities. This wearable sensor of nucleic acids will probably be of great significance in the field of online pathogen detection for wounds, for tumour biomarker diagnosis, and for the detection of epidermal cell molecular lesions.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Yang et al. introduced a bandage-like wearable detector of nucleic acids with a detection limit of 10 copies/μL.
“Yang et al. [311] introduces a novel bandage-like wearable detector of nucleic acids. The sensor uses flexible microfluidic recombinase polymerase amplification and offers excellent sensitivity and selectivity with a detection limit of 10 copies/μL.”
From The Current State of Optical Sensors in Medical Wearables (2022) · cites this paper as [311]
Cites
Analyzing real-time PCR data by the comparative CT method
Schmittgen, T. D., & Livak, K. J. (2008) · Nature Protocols · doi:10.1038/nprot.2008.73 · Cited by 26,190 · see citing works
Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis
Gao, W., Emaminejad, S., Nyein, H. Y. Y., Challa, S., Chen, K., Peck, A., Fahad, H. M., Ota, H., Shiraki, H., Kiriya, D., et al. (2016) · Nature · doi:10.1038/nature16521 · Cited by 5,087 · see citing works
DNA Detection Using Recombination Proteins
Piepenburg, O., Williams, C. H., Stemple, D. L., & Armes, N. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040204 · Cited by 2,503 · see citing works
Contact angle measurement and contact angle interpretation
Kwok, D. Y., & Neumann, A. W. (1999) · Advances in Colloid and Interface Science · doi:10.1016/s0001-8686(98)00087-6 · Cited by 1,678 · see citing works
Wearable sensors: modalities, challenges, and prospects
Heikenfeld, J., Jajack, A., Rogers, J., Gutruf, P., Tian, L., Pan, T., Li, R., Khine, M., Kim, J., Wang, J., et al. (2018) · Lab on a Chip · doi:10.1039/c7lc00914c · Cited by 1,434 · see citing works
A soft, wearable microfluidic device for the capture, storage, and colorimetric sensing of sweat
Koh, A., Kang, D., Xue, Y., Lee, S., Pielak, R. M., Kim, J., Hwang, T., Min, S., Banks, A., Bastien, P., et al. (2016) · Science Translational Medicine · doi:10.1126/scitranslmed.aaf2593 · Cited by 1,308 · see citing works
Inflammation-free, gas-permeable, lightweight, stretchable on-skin electronics with nanomeshes
Miyamoto, A., Lee, S., Cooray, N. F., Lee, S., Mori, M., Matsuhisa, N., Jin, H., Yoda, L., Yokota, T., Itoh, A., et al. (2017) · Nature Nanotechnology · doi:10.1038/nnano.2017.125 · Cited by 1,181 · see citing works
Lee, H., Song, C., Hong, Y. S., Kim, M., Cho, H. R., Kang, T., Shin, K., Choi, S. H., Hyeon, T., & Kim, D.-H. (2017) · Science Advances · doi:10.1126/sciadv.1601314 · Cited by 1,118 · see citing works
Wearable smart sensor systems integrated on soft contact lenses for wireless ocular diagnostics
Kim, J., Kim, M., Lee, M.-S., Kim, K., Ji, S., Kim, Y.-T., Park, J., Na, K., Bae, K.-H., Kyun Kim, H., et al. (2017) · Nature Communications · doi:10.1038/ncomms14997 · Cited by 951 · see citing works
Yu, J., Zhang, Y., Ye, Y., DiSanto, R., Sun, W., Ranson, D., Ligler, F. S., Buse, J. B., & Gu, Z. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1505405112 · Cited by 852 · see citing works
Nyein, H. Y. Y., Gao, W., Shahpar, Z., Emaminejad, S., Challa, S., Chen, K., Fahad, H. M., Tai, L.-C., Ota, H., Davis, R. W., et al. (2016) · ACS Nano · doi:10.1021/acsnano.6b04005 · Cited by 669 · see citing works
An ingestible bacterial-electronic system to monitor gastrointestinal health
Mimee, M., Nadeau, P., Hayward, A., Carim, S., Flanagan, S., Jerger, L., Collins, J., McDonnell, S., Swartwout, R., Citorik, R. J., et al. (2018) · Science · doi:10.1126/science.aas9315 · Cited by 606 · see citing works
Wearable non-invasive epidermal glucose sensors: A review
Kim, J., Campbell, A. S., & Wang, J. (2017) · Talanta · doi:10.1016/j.talanta.2017.08.077 · Cited by 585 · see citing works
Bandodkar, A. J., Molinnus, D., Mirza, O., Guinovart, T., Windmiller, J. R., Valdés-Ramírez, G., Andrade, F. J., Schöning, M. J., & Wang, J. (2014) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2013.11.039 · Cited by 490 · see citing works
Skin-like biosensor system via electrochemical channels for noninvasive blood glucose monitoring
Chen, Y., Lu, S., Zhang, S., Li, Y., Qu, Z., Chen, Y., Lu, B., Wang, X., & Feng, X. (2017) · Science Advances · doi:10.1126/sciadv.1701629 · Cited by 470 · see citing works
Battery-free, stretchable optoelectronic systems for wireless optical characterization of the skin
Kim, J., Salvatore, G. A., Araki, H., Chiarelli, A. M., Xie, Z., Banks, A. R., Sheng, X., Liu, Y., Lee, J. W., Jang, K., et al. (2016) · Science Advances · doi:10.1126/sciadv.1600418 · Cited by 407 · see citing works
Battery-free, wireless sensors for full-body pressure and temperature mapping
Han, S., Kim, J., Won, S. M., Ma, Y., Kang, D., Xie, Z., Lee, K., Chung, H. U., Banks, A. R., Min, S., et al. (2018) · Science Translational Medicine · doi:10.1126/scitranslmed.aan4950 · Cited by 356 · see citing works
Lipani, L., Dupont, B. G. R., Doungmene, F., Marken, F., Tyrrell, R. M., Guy, R. H., & Ilie, A. (2018) · Nature Nanotechnology · doi:10.1038/s41565-018-0112-4 · Cited by 340 · see citing works
Factors influencing Recombinase polymerase amplification (RPA) assay outcomes at point of care
Lillis, L. L., Siverson, J. B., Lee, A., Cantera, J. L., Parker, M., Piepenburg, O., Lehman, D. A., & Boyle, D. S. (2016) · Molecular and Cellular Probes · doi:10.1016/j.mcp.2016.01.009 · Cited by 206 · see citing works
A Microfluidic Rectifier: Anisotropic Flow Resistance at Low Reynolds Numbers
Groisman, A., & Quake, S. R. (2004) · Physical Review Letters · doi:10.1103/physrevlett.92.094501 · Cited by 203 · see citing works
Sultan, N. A. (2015) · International Journal of Information Management · doi:10.1016/j.ijinfomgt.2015.04.010 · Cited by 197 · see citing works
Gowers, S. A. N., Curto, V. F., Seneci, C., Wang, C., Anastasova, S., Vadgama, P. M., Yang, G., & Boutelle, M. G. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b01353 · Cited by 193 · see citing works
Kim, S. B., Zhang, Y., Won, S. M., Bandodkar, A. J., Sekine, Y., Xue, Y., Koo, J., Harshman, S. W., Martin, J. A., Park, J. M., et al. (2018) · Small · doi:10.1002/smll.201703334 · Cited by 167 · see citing works
Recent Advances in Solid Nanopore/Channel Analysis
Long, Z., Zhan, S., Gao, P., Wang, Y., Lou, X., & Xia, F. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b04737 · Cited by 117 · see citing works
Quantification of HIV-1 DNA Using Real-Time Recombinase Polymerase Amplification
Crannell, Z. A., Rohrman, B. A., & Richards‐Kortum, R. (2014) · Analytical Chemistry · doi:10.1021/ac5011298 · Cited by 97 · see citing works
Wang, R., Zhang, F., Wang, L., Qian, W., Qian, C., Wu, J. F., & Ying, Y. B. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b00964 · Cited by 91 · see citing works
Cleavage-based signal amplification of RNA
Zhao, Y., Zhou, L., & Tang, Z. (2013) · Nature Communications · doi:10.1038/ncomms2492 · Cited by 86 · see citing works
Superwettable Microchips as a Platform toward Microgravity Biosensing
Xu, T., Shi, W., Huang, J., Song, Y., Zhang, F., Xu, L., Zhang, X., & Wang, S. (2016) · ACS Nano · doi:10.1021/acsnano.6b06896 · Cited by 83 · see citing works
Gao, W., Wang, C., Muzyka, K., Kitte, S. A., Li, J., Zhang, W., & Xu, G. (2017) · Analytical Chemistry · doi:10.1021/acs.analchem.7b01000 · Cited by 83 · see citing works
Flexible Superwettable Tapes for On-Site Detection of Heavy Metals
He, X., Xu, T., Gao, W. F., Xu, L., Pan, T., & Zhang, X. (2018) · Analytical Chemistry · doi:10.1021/acs.analchem.8b04536 · Cited by 67 · see citing works
Gao, Z. F., Sann, E. E., Lou, X., Liu, R., Dai, J., Zuo, X., Xia, F., & Jiang, L. (2018) · NPG Asia Materials · doi:10.1038/s41427-018-0024-7 · Cited by 66 · see citing works
Coffey, J. W., Corrie, S. R., & Kendall, M. A. F. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.03.039 · Cited by 45 · see citing works
Dao, T. N. T., Lee, E. Y., Koo, B., Jin, C. E., Lee, T. Y., & Shin, Y. M. (2017) · Analytical Biochemistry · doi:10.1016/j.ab.2017.12.030 · Cited by 44 · see citing works
Shen, Y., Abolhasani, M., Chen, Y., Xie, L., Lu, Y., Coley, C. W., Bawendi, M. G., & Jensen, K. F. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201710899 · Cited by 39 · see citing works
Dossi, N., Petrazzi, S., Terzi, F., Toniolo, R., & Bontempelli, G. (2019) · Talanta · doi:10.1016/j.talanta.2019.01.126 · Cited by 27 · see citing works
Surface Molding of Microscale Hydrogels with Microactuation Functionality
Bowen, J. J., Rose, M. A., Konda, A., & Morin, S. A. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201710612 · Cited by 26 · see citing works
Surface Molding of Microscale Hydrogels with Microactuation Functionality
Bowen, J. J., Rose, M. A., Konda, A., & Morin, S. A. (2017) · Angewandte Chemie · doi:10.1002/ange.201710612 · Cited by 6 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Point-of-care diagnostics for infectious diseases: From methods to devices
Wang, C., Liu, M., Wang, Z., Song, L., Deng, Y., & He, N. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101092 · Cited by 627 · see citing works
Materials with Tunable Optical Properties for Wearable Epidermal Sensing in Health Monitoring
Han, F., Wang, T., Liu, G., Liu, H., Xie, X., Wei, Z., Li, J., Jiang, C., He, Y., & Xu, F. (2022) · Advanced Materials · doi:10.1002/adma.202109055 · Cited by 250 · see citing works
Wearable Bioelectronics for Chronic Wound Management
Wang, C., Sani, E. S., & Gao, W. F. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202111022 · Cited by 211 · see citing works
Zhang, M., Wang, X., Feng, H., Huang, Q., Xiao, X., & Zhang, X. (2021) · Journal of Cleaner Production · doi:10.1016/j.jclepro.2021.127712 · Cited by 172 · see citing works
Advanced “lab-on-a-chip” to detect viruses – Current challenges and future perspectives
Zhuang, J., Yin, J., Lv, S., Wang, B., & Mu, Y. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112291 · Cited by 156 · see citing works
Isothermal Nucleic Acid Amplification Techniques and Their Use in Bioanalysis
Bodulev, O. L., & Sakharov, I. Y. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920020030 · Cited by 127 · see citing works
Microfluidic devices for detection of RNA viruses
Basiri, A., Heidari, A., Nadi, M. F., Pahlevan‐Fallahy, M., Nezamabadi, S. S., Sedighi, M., Saghazadeh, A., & Rezaei, N. (2020) · Reviews in Medical Virology · doi:10.1002/rmv.2154 · Cited by 121 · see citing works
Visual detection for nucleic acid-based techniques as potential on-site detection methods. A review
Zhang, M., Ye, J., He, J., Zhang, F., Ping, J. F., Qian, C., & Wu, J. F. (2019) · Analytica Chimica Acta · doi:10.1016/j.aca.2019.11.056 · Cited by 112 · see citing works
Chakraborty, S. K. (2024) · Sensors & Diagnostics · doi:10.1039/d3sd00304c · Cited by 105 · see citing works
Recent developments of point-of-care (POC) testing platform for biomolecules
Manmana, Y., Kubo, T., & Otsuka, K. (2020) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2020.116160 · Cited by 103 · see citing works
The Current State of Optical Sensors in Medical Wearables
Vavrinsky, E., Esfahani, N. E., Hausner, M., Kuzma, A., Rezo, V., Donoval, M., & Kosnacova, H. (2022) · Biosensors · doi:10.3390/bios12040217 · Cited by 103 · see citing works
Microfluidics-based strategies for molecular diagnostics of infectious diseases
Wang, X., Hong, X., Li, Y., Li, Y., Wang, J., Chen, P., & Liu, B. (2022) · Military Medical Research · doi:10.1186/s40779-022-00374-3 · Cited by 96 · see citing works
A fully automated centrifugal microfluidic system for sample-to-answer viral nucleic acid testing
Tian, F., Liu, C., Deng, J., Han, Z., Zhang, L., Chen, Q., & Sun, J. (2020) · Science China Chemistry · doi:10.1007/s11426-020-9800-6 · Cited by 83 · see citing works
Point-of-care testing: a critical analysis of the market and future trends
Khan, A. R., Hussain, W. L., Shum, H. C., & Hassan, S. U. (2024) · Frontiers in Lab on a Chip Technologies · doi:10.3389/frlct.2024.1394752 · Cited by 77 · see citing works
Bai, Y., Ji, J., Ji, F., Wu, S., Tian, Y., Jin, B., & Li, Z. (2022) · Talanta · doi:10.1016/j.talanta.2022.123209 · Cited by 75 · see citing works
Zhou, S., Dong, J., Deng, L., Wang, G., Yang, M. J., Wang, Y., Huo, D., & Hou, C. (2022) · ACS Sensors · doi:10.1021/acssensors.2c01330 · Cited by 70 · see citing works
Yu, Y., Bu, F., Zhou, H., Wang, Y., Cui, J., Wang, X., Nie, G., & Xiao, H. (2020) · Materials Chemistry Frontiers · doi:10.1039/d0qm00255k · Cited by 71 · see citing works
Gao, J., Shang, K., Ding, Y., & Wen, Z. (2021) · Journal of Materials Chemistry A · doi:10.1039/d0ta11260g · Cited by 68 · see citing works
Smart Dressings for Wound Healing: A Review
Almeida, I. B., Teixeira, L. G. B., de Carvalho, F. O., Silva, É. R., Nunes, P. S., dos Santos, M. R. V., & Araújo, A. A. D. S. (2021) · Advances in Skin & Wound Care · doi:10.1097/01.asw.0000725188.95109.68 · Cited by 68 · see citing works
Gao, D., Guo, X., Yang, Y., Shi, H., Hao, R., Wang, S., Li, Z. J., Zhao, R., & Song, H. (2022) · Journal of Biological Engineering · doi:10.1186/s13036-022-00312-w · Cited by 65 · see citing works
dos Santos, C. C., Lucena, G. N., Pinto, G. C., Jafelicci, M., & Marques, R. F. C. (2020) · Medical Devices & Sensors · doi:10.1002/mds3.10130 · Cited by 65 · see citing works
Wearable chem-biosensing devices: from basic research to commercial market
Yang, B., Jiang, X., Fang, X., & Kong, J. (2021) · Lab on a Chip · doi:10.1039/d1lc00438g · Cited by 64 · see citing works
Mota, D. S., Guimarães, J. M., Gandarilla, A. M. D., Filho, J. C. B. S., Brito, W. R., & Mariúba, L. A. M. (2022) · Canadian Journal of Microbiology · doi:10.1139/cjm-2021-0329 · Cited by 61 · see citing works
Molecular point-of-care testing technologies: Current status and challenges
Zu, Y., Chang, H., & Cui, Z. (2025) · Nexus · doi:10.1016/j.ynexs.2025.100059 · Cited by 53 · see citing works
Zhang, S., Duan, M., Li, S., Hou, J., Qin, T., Teng, Z., Hu, J., Zhang, H., & Xia, X. (2023) · Diagnostic Microbiology and Infectious Disease · doi:10.1016/j.diagmicrobio.2023.116097 · Cited by 50 · see citing works
Popescu, M., & Ungureanu, C. (2023) · Coatings · doi:10.3390/coatings13030486 · Cited by 46 · see citing works
Application of antiviral materials in textiles: A review
Zhang, Y., Fan, W., Sun, Y., Chen, W., & Zhang, Y. (2021) · Nanotechnology Reviews · doi:10.1515/ntrev-2021-0072 · Cited by 45 · see citing works
Dhar, B. (2022) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-022-03918-7 · Cited by 45 · see citing works
Hu, J., Liu, Y., Zhang, X., Han, H., Li, Z., & Han, T. (2021) · Dyes and Pigments · doi:10.1016/j.dyepig.2021.109393 · Cited by 41 · see citing works
Recombinase Polymerase Amplification-Based Biosensors for Rapid Zoonoses Screening
Feng, X., Liu, Y., Zhao, Y., Sun, Z., Xu, N., Zhao, C., & Xia, W. (2023) · International Journal of Nanomedicine · doi:10.2147/ijn.s434197 · Cited by 40 · see citing works
Recent progress in CRISPR-based microfluidic assays and applications
Li, P., Xiong, H., Yang, B., Jiang, X., Kong, J., & Fang, X. (2022) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2022.116812 · Cited by 40 · see citing works
Hsieh, K., Melendez, J. H., Gaydos, C. A., & Wang, T. (2021) · Lab on a Chip · doi:10.1039/d1lc00665g · Cited by 39 · see citing works
Trinh, K. T. L., & Lee, N. Y. (2022) · Biosensors · doi:10.3390/bios12020072 · Cited by 36 · see citing works
Advances in wearable electrochemical antibody-based sensors for cortisol sensing
Khumngern, S., & Jeerapan, I. (2023) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-023-04577-y · Cited by 38 · see citing works
Janghorban, M., Aradanas, I., Kazemi, S., Ngaju, P., & Pandey, R. (2022) · Biosensors · doi:10.3390/bios12110986 · Cited by 35 · see citing works
Li, Q., Duan, L., Jin, D., Chen, Y., Lou, Y., Zhou, Q., Xu, Z.-J., Chen, F., Chen, H., Xu, G., et al. (2023) · Aquaculture · doi:10.1016/j.aquaculture.2023.740017 · Cited by 32 · see citing works
Point-of-Care DNA Amplification for Disease Diagnosis and Management
Botella, J. R. (2022) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-021621-115027 · Cited by 31 · see citing works
Kang, Y. K., Im, S. H., Ryu, J. S., Lee, J., & Chung, H. J. (2020) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2020.112566 · Cited by 28 · see citing works
Ren, Z., & Cui, Y. (2026) · Lab on a Chip · doi:10.1039/d5lc00892a · Cited by 28 · see citing works
Jeerapan, I., Sonsa‐ard, T., & Nacapricha, D. (2020) · Chemosensors · doi:10.3390/chemosensors8030071 · Cited by 26 · see citing works
Uyanga, K. A., Li, W., & Daoud, W. A. (2024) · European Polymer Journal · doi:10.1016/j.eurpolymj.2024.113041 · Cited by 25 · see citing works
Public-Health-Driven Microfluidic Technologies: From Separation to Detection
Zhang, X., Xu, X., Wang, J., Wang, C., Yan, Y., Wu, A., & Ren, Y. (2021) · Micromachines · doi:10.3390/mi12040391 · Cited by 24 · see citing works
Biswas, G. C., Khan, M. T. M., & Das, J. (2023) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2023.115115 · Cited by 24 · see citing works
Recent trends in non-invasive on-body chemical sensing
Boeva, Z. A., Mousavi, Z., Sokalski, T., & Bobacka, J. (2024) · TrAC Trends in Analytical Chemistry · doi:10.1016/j.trac.2024.117542 · Cited by 22 · see citing works
Guler, M. T., İnal, M., & Bilican, İ. (2021) · Journal of Industrial and Engineering Chemistry · doi:10.1016/j.jiec.2021.03.033 · Cited by 22 · see citing works
Microfluidics for COVID-19: From Current Work to Future Perspective
Li, Q., Zhou, X., Wang, Q., Liu, W., & Chen, C. (2023) · Biosensors · doi:10.3390/bios13020163 · Cited by 22 · see citing works
Emerging Landscape of SARS-CoV-2 Variants and Detection Technologies
Li, X., Wang, J., Geng, J., Xiao, L., & Wang, H. (2022) · Molecular Diagnosis & Therapy · doi:10.1007/s40291-022-00631-0 · Cited by 19 · see citing works
New advances in signal amplification strategies for DNA methylation detection in vitro
Cai, J., & Zhu, Q. (2024) · Talanta · doi:10.1016/j.talanta.2024.125895 · Cited by 18 · see citing works
Zoonotic disease detection at the point-of-care: the best of RPA and CRISPR-Cas
dos Santos, S. M. B., Tricht, C. V., Lammertyn, J., & Spasić, D. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.118139 · Cited by 16 · see citing works
Bellassai, N., D’Agata, R., & Spoto, G. (2025) · Sensors and Actuators Reports · doi:10.1016/j.snr.2025.100285 · Cited by 14 · see citing works
Zhang, M., Li, G., Zhao, X., Duan, Y., Liao, Y., & Han, T. (2022) · Dyes and Pigments · doi:10.1016/j.dyepig.2022.110561 · Cited by 14 · see citing works
Rapid Detection of Clostridium tetani by Recombinase Polymerase Amplification Using an Exo Probe
Guo, M., Feng, P., Zhang, L., Feng, C., Fu, J., Pu, X., & Liu, F. (2021) · Journal of Microbiology and Biotechnology · doi:10.4014/jmb.2109.09022 · Cited by 13 · see citing works
Flexible biochemical sensors for point-of-care management of diseases: a review
He, F., Li, K., Lv, X., Zeng, Q., Zhu, Y., Li, X., & Deng, Y. (2022) · Microchimica Acta · doi:10.1007/s00604-022-05469-1 · Cited by 13 · see citing works
Smart Solutions for Control and Management in Livestock Farms
Paunova-Hubenova, E., & Trichkova-Kashamova, E. (2021) · International Conference on Big Data, Knowledge and Control Systems Engineering (BdKCSE) · doi:10.1109/bdkcse53180.2021.9627269 · Cited by 11 · see citing works
Paper‐Based Bacterial Lysis Enables Sample‐to‐Answer Home‐based DNA Testing
Chondrogiannis, G., Réu, P., & Hamedi, M. M. (2022) · Advanced Materials Technologies · doi:10.1002/admt.202201004 · Cited by 11 · see citing works
Jeerapan, I., Moonla, C., Thavarungkul, P., & Kanatharana, P. (2022) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2021.07.025 · Cited by 9 · see citing works
Comparative analysis of methods for isothermal amplification of nucleic acids
Чемисова, О. С., Цырулина, О. А., Trukhachev, A. L., & Носков, А. К. (2022) · Journal of microbiology epidemiology immunobiology · doi:10.36233/0372-9311-176 · Cited by 8 · see citing works
Pang, X., Lei, Z., Ji, J., Li, F., Mu, X., Wang, H., Dong, W., & Mei, Q. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117479 · Cited by 7 · see citing works
Mota, F. B., Braga, L. A. M., Cabral, B. P., & Filho, C. G. C. (2021) · foresight · doi:10.1108/fs-05-2021-0101 · Cited by 7 · see citing works
Flexible and mountable microfluidics for wearable biosensors
Meng, L., Jeerapan, I., & Mak, W. C. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-823846-2.00005-5 · Cited by 6 · see citing works
The T-Blep: A Soft Optical Sensor for Stiffness and Contact Force Measurement
Bernabei, F., Preti, M. L., & Beccai, L. (2024) · Micromachines · doi:10.3390/mi15020233 · Cited by 6 · see citing works
Nucleotide detection mechanism and comparison based on low-dimensional materials: A review
Azeem, M. M., Shafa, M., Aamir, M., Zubair, M., Souayeh, B., & Alam, M. W. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1117871 · Cited by 5 · see citing works
Advancements in Airborne Viral Nucleic Acid Detection with Wearable Devices
Godin, R., Hejazi, S., & Reuel, N. F. (2023) · Advanced Sensor Research · doi:10.1002/adsr.202300061 · Cited by 5 · see citing works
Microneedle-based detection of nucleic acids in interstitial fluid: A review
Liu, H., Zheng, H., Peng, N., & Hu, F. (2025) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2025.117996 · Cited by 4 · see citing works
Tullayaprayouch, K., Phuadraksa, T., Luk-in, S., Pornsuwan, S., Changkhundi, P., Wichit, S., & Yainoy, S. (2025) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2025.107567 · Cited by 4 · see citing works
Nakano, M., Inaba, M., & Suehiro, J. (2021) · The Analyst · doi:10.1039/d0an02349c · Cited by 4 · see citing works
Costa‐Rama, E., & Fernández-Abedul, M. T. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821661-3.00008-2 · Cited by 5 · see citing works
Cong, H., Han, X., Lv, M., Chang, Y., Wang, X., & Lei, R. (2025) · Talanta · doi:10.1016/j.talanta.2025.128195 · Cited by 3 · see citing works
Design and Fabrication of Wearable Biosensors: Materials, Methods, and Prospects
Gajjala, R. K. R., Muñana-González, S., Núñez-Marinero, P., Totoricaguena-Gorriño, J., Ruiz‐Rubio, L., & del Campo, F. J. (2024) · Springer eBooks · doi:10.1007/978-981-99-8122-9_15 · Cited by 3 · see citing works
Priya, R., Dubey, S. K., & Goel, S. (2024) · IEEE Open Journal of Engineering in Medicine and Biology · doi:10.1109/ojemb.2024.3477315 · Cited by 3 · see citing works
Wearable technology in healthcare engineering
Mehta, S., & Sharma, D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91182-5.00005-x · Cited by 3 · see citing works
Use of Wearable Devices for Body Monitoring: An Innovative Review
Huaytalla-Pariona, J., Pillaca-Ccasani, J., Sota-Shicshe, C. D. L., Villanueva-López, F. D., Escobar-Baquerizo, S., Salcedo-Huamani, J., & Huamanchahua, D. (2024) · IEEE Colombian Conference on Communications and Computing (COLCOM) · doi:10.1109/colcom62950.2024.10720314 · Cited by 3 · see citing works
Justo, C. A. C., Acosta, S. J., Jauset‐Rubio, M., Skouridou, V., Mulinganya, G. M., Cools, P., Rivera, W. L., & O’Sullivan, C. K. (2025) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.5c00147 · Cited by 2 · see citing works
Nucleic acid based biosensor as a cutting edge tool for point of care diagnosis
Shah, S., Maharshi, A., Pandya, M. D., Dhanalakshmi, M., & Das, K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-88464-8.00014-2 · Cited by 2 · see citing works
Energy Harvesting in IoT-Enabled Flexible Sensors: Smart Sensing and Secure Access Control
Pal, S., & Nag, A. (2022) · Smart sensors, measurement and instrumentation · doi:10.1007/978-3-030-99600-0_9 · Cited by 1 · see citing works
You, J., Jun, H., Lei, L., Yang, L., Min, D., Ma, C., Xuliang, Z., Xiaobo, F., & Hui, C. (2025) · Microbial Pathogenesis · doi:10.1016/j.micpath.2025.108064 · Cited by 1 · see citing works
Wang, J., Wang, S., & Zhang, J. (2025) · Flexible and Printed Electronics · doi:10.1088/2058-8585/adb8fa · Cited by 1 · see citing works
Particles Separation in Microfluidic Devices, Volume II
Nisisako, T., & Tottori, N. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-3673-6
Li, C.-J., Sun, H.-Q., Zhao, W., Wang, X., Lin, R., & Yao, Y. (2023) · Research Square · doi:10.21203/rs.3.rs-2744727/v1
Nuts and Bolts of Modern Biosensing Technology: Smart Health Diagnostic Devices
Jeerapan, I., Valdés‐Ramírez, G., & Brunetti, B. (2023) · Wiley eBooks · doi:10.1002/9783527837946.ch2
Chip-based nanotechnology in the molecular pathology laboratory and beyond
Laurentius, L. B., Clarke, E., Lambert, C. J., Patel, D., Mahmood, T., Zang, L., Sant, H. J., Gale, B. K., & Porter, M. D. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-822824-1.00008-0
Pang, X., Lei, Z., Ji, J., Li, F., Mu, X., Wang, H., Dong, W., & Mei, Q. (2024) · SSRN Electronic Journal · doi:10.2139/ssrn.5065692
Trinh, T. N. D., Dinh, V. P., Nguyen, H. A., Phuong, N. T. T., Chae, W. R., Lee, N. Y., Somoza, Á., & Trinh, K. T. L. (2026) · Advanced Materials Technologies · doi:10.1002/admt.71351
- Authors
- Yang, B., Kong, J., & Fang, X.
- Affiliations
- Fudan University (CN)
- Corresponding author
- Kong, Jilie
- Fang, Xueen
- Venue
- Talanta
- Publisher
- Elsevier BV
- Published
- 2019-11
- Volume
- 204
- Pages
- 685-692
- ISSN
- 0039-9140 (ISSN-L)
- OpenAlex
- W2949311621
- Cited by
- 83
- References
- 37
- Citations by year
- 2026: 2 · 2025: 10 · 2024: 10 · 2023: 13 · 2022: 23 · 2021: 15 · 2020: 9 · 2019: 1
- FWCI
- 4.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Talanta (publishedVersion)
- PubMed (publishedVersion)
- Funders
- National Natural Science Foundation of China (21505024, 21427806, 21175029, 21335002)
- Introduce Talents of Fudan University Research Funding (JIH1615032)
- Shanghai Leading Academic Discipline Project (B109)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Biosensors and Analytical Detection
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 detection and testing
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Keywords
- recombinase polymerase amplification, wearable biosensors, flexible microfluidics, Zika virus detection
- MeSH terms
- Point-of-Care Testing, Zika Virus, Proof of Concept Study, Bandages, Colorimetry, DNA, Viral, Fluorescent Dyes, Hot Temperature, Humans, Intercalating Agents, Reproducibility of Results, Nucleic Acid Amplification Techniques, Microfluidic Analytical Techniques, Lab-On-A-Chip Devices, Limit of Detection
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
