Cited by 264Gut microbiota and healthInfant Nutrition and HealthProbiotics and Fermented Foods

Glycan Utilization and Cross-Feeding Activities by Bifidobacteria

Turroni, Francesca, Milani, Christian, Duranti, Sabrina, Mahony, Jennifer, van Sinderen, Douwe, Ventura, Marco·2018·Trends in Microbiology

Abstract

Bifidobacteria represent one of the first colonizers of the mammalian gut, where such colonization is facilitated by their saccharolytic capabilities. Genomic analyses of bifidobacteria have revealed intriguing genetic strategies employed by these bacteria to access a variety of dietary and host-produced glycans. Bifidobacterial genome evolution therefore represents a fascinating example of how their chromosomes were molded to contain a large number of genes involved in carbohydrate metabolism. One of the reasons as to why bifidobacteria are such dominant and prevalent members of the (early) microbiota is that they may access glycans in the gut through mutualistic cross-feeding or resource-sharing activities, which is indicative of 'social behavior' among bifidobacterial strains.

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Crossref · 10.1016/j.tim.2017.10.001

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Authors
Turroni, F., Milani, C., Duranti, S., Mahony, J., van Sinderen, D., & Ventura, M.
Affiliations
  • University of Parma (IT)
  • National University of Ireland (IE)
Corresponding author
Ventura, Marco
Venue
Trends in Microbiology
Publisher
Elsevier BV
Published
2018-04
Volume
26
Issue
4
Pages
339-350
ISSN
0966-842X (ISSN-L)
OpenAlex
W2766892303
Cited by
263
References
84
Citations by year
2026: 19 · 2025: 27 · 2024: 31 · 2023: 39 · 2022: 43 · 2021: 37 · 2020: 31 · 2019: 22 · 2018: 13 · 2017: 1
FWCI
1.75
Type
journal article
Language
en
Open access
closed
Locations
  • Trends in Microbiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • EU Joint Programming Initiative – A Healthy Diet for a Healthy Life
  • MIUR
  • Science Foundation Ireland (SFI/12/RC/2273)
  • Starting Investigator Research (15/SIRG/3430)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords
Bifidobacterium, cross-feeding, mutualism, carbohydrate metabolism, gut microbiota, bacterial genome evolution, saccharolytic bacteria, resource sharing
MeSH terms
Gastrointestinal Microbiome, Adaptation, Biological, Bifidobacterium, Ecology, Biological Evolution, Humans, Polysaccharides, Genome, Bacterial, Probiotics, Gastrointestinal Tract, Carbohydrate Metabolism, Metagenomics

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