Bifidobacteria exhibit social behavior through carbohydrate resource sharing in the gut

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works

Molecular Cloning: A Laboratory Manual

Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589 · see citing works

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Love, M. I., Huber, W., & Anders, S. (2014) · Genome Biology · doi:10.1186/s13059-014-0550-8 · Cited by 95,106 · see citing works

The Sequence Alignment/Map format and SAMtools

Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R., & 1000 Genome Project Data Processing Subgroup (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp352 · Cited by 62,041 · see citing works

Fast and accurate short read alignment with Burrows-Wheeler transform

Li, H., & Durbin, R. (2009) · Bioinformatics · doi:10.1093/bioinformatics/btp324 · Cited by 58,607 · see citing works

Fast gapped-read alignment with Bowtie 2

Langmead, B., & Salzberg, S. L. (2012) · Nature Methods · doi:10.1038/nmeth.1923 · Cited by 56,400 · see citing works

BEDTools: a flexible suite of utilities for comparing genomic features

Quinlan, A. R., & Hall, I. M. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq033 · Cited by 27,437 · see citing works

Structure, function and diversity of the healthy human microbiome

The Human Microbiome Project Consortium (2012) · Nature · doi:10.1038/nature11234 · Cited by 11,726 · see citing works

A Laboratory manual

Ashburner, M. (1989) · Cold Spring Harbor Laboratory eBooks · Cited by 6,739 · see citing works

The carbohydrate-active enzymes database (CAZy) in 2013

Lombard, V., Ramulu, H. G., Drula, É., Coutinho, P. M., & Henrissat, B. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt1178 · Cited by 6,355 · see citing works

Metagenomic Analysis of the Human Distal Gut Microbiome

Gill, S. R., Pop, M., DeBoy, R. T., Eckburg, P. B., Turnbaugh, P. J., Samuel, B. S., Gordon, J. I., Relman, D. A., Fraser-Liggett, C. M., & Nelson, K. E. (2006) · Science · doi:10.1126/science.1124234 · Cited by 4,699 · see citing works

Phylogenomics resolves the timing and pattern of insect evolution

Misof, B., Liu, S., Meusemann, K., Peters, R. S., Donath, A., Mayer, C., Frandsen, P. B., Ware, J., Flouri, T., Beutel, R. G., et al. (2014) · Science · doi:10.1126/science.1257570 · Cited by 2,694 · see citing works

Metagenomic microbial community profiling using unique clade-specific marker genes

Segata, N., Waldron, L., Ballarini, A., Narasimhan, V., Jousson, O., & Huttenhower, C. (2012) · Nature Methods · doi:10.1038/nmeth.2066 · Cited by 1,776 · see citing works

The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

Kaoutari, A. E., Armougom, F., Gordon, J. I., Raoult, D., & Henrissat, B. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro3050 · Cited by 1,683 · see citing works

How glycan metabolism shapes the human gut microbiota

Koropatkin, N. M., Cameron, E. A., & Martens, E. C. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2746 · Cited by 1,419 · see citing works

The genome sequence of Bifidobacterium longum subsp. infantis reveals adaptations for milk utilization within the infant microbiome

Sela, D. A., Chapman, J., Adeuya, A., Kim, J., Chen, F., Whitehead, T. R., Lapidus, A. L., Rokhsar, D. S., Lebrilla, C. B., German, J. B., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809584105 · Cited by 878 · see citing works

Carbohydrate metabolism in Bifidobacteria

Pokusaeva, K., Fitzgerald, G. F., & van Sinderen, D. (2011) · Genes & Nutrition · doi:10.1007/s12263-010-0206-6 · Cited by 855 · see citing works

Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology

Karp, P. D., Paley, S. M., Krummenacker, M., Latendresse, M., Dale, J. M., Lee, T. J., Kaipa, P., Gilham, F., Spaulding, A., Popescu, L., et al. (2010) · Briefings in Bioinformatics · doi:10.1093/bib/bbp043 · Cited by 694 · see citing works

eggNOG v4.0: nested orthology inference across 3686 organisms

Powell, S., Forslund, K., Szklarczyk, D., Trachana, K., Roth, A., Huerta-Cepas, J., Gabaldón, T., Rattei, T., Creevey, C., Kuhn, M., et al. (2014) · Nucleic Acids Research · doi:10.1093/nar/gkt1253 · Cited by 652 · see citing works

Diversity of Bifidobacteria within the Infant Gut Microbiota

Turroni, F., Peano, C., Pass, D. A., Foroni, E., Severgnini, M., Claesson, M. J., Kerr, C., Hourihane, J., Murray, D., Fuligni, F., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0036957 · Cited by 647 · see citing works

SUPERFAMILY—sophisticated comparative genomics, data mining, visualization and phylogeny

Wilson, D. A., Pethica, R., Zhou, Y., Talbot, C. C., Vogel, C., Madera, M., Chothia, C., & Gough, J. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn762 · Cited by 488 · see citing works

The Biochemistry of Sugars and Polysaccharides in Insects

Wyatt, G. R. (1967) · Advances in insect physiology · doi:10.1016/s0065-2806(08)60210-6 · Cited by 482 · see citing works

Genome-scale analyses of health-promoting bacteria: probiogenomics

Ventura, M., O'Flaherty, S., Claesson, M. J., Turroni, F., Klaenhammer, T. R., van Sinderen, D., & O'Toole, P. W. (2009) · Nature Reviews Microbiology · doi:10.1038/nrmicro2047 · Cited by 471 · see citing works

Genomic and Metabolic Studies of the Impact of Probiotics on a Model Gut Symbiont and Host

Sonnenburg, J. L., Chen, C. T. L., & Gordon, J. I. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040413 · Cited by 423 · see citing works

Genome analysis of <i>Bifidobacterium bifidum</i> PRL2010 reveals metabolic pathways for host-derived glycan foraging

Turroni, F., Bottacini, F., Foroni, E., Mulder, I., Kim, J.-H., Zomer, A., Sánchez, B., Bidossi, A., Ferrarini, A., Giubellini, V., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1011100107 · Cited by 364 · see citing works

Xylan biosynthesis

Rennie, E. A., & Scheller, H. V. (2013) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2013.11.013 · Cited by 321 · see citing works

Exploring the Diversity of the Bifidobacterial Population in the Human Intestinal Tract

Turroni, F., Foroni, E., Pizzetti, P., Giubellini, V., Ribbera, A., Merusi, P., Cagnasso, P., Bizzarri, B., de'Angelis, G. L., Shanahan, F., et al. (2009) · Applied and Environmental Microbiology · doi:10.1128/aem.02216-08 · Cited by 311 · see citing works

Assessing the Fecal Microbiota: An Optimized Ion Torrent 16S rRNA Gene-Based Analysis Protocol

Milani, C., Hevia, A., Foroni, E., Duranti, S., Turroni, F., Lugli, G. A., Sánchez, B., Martín, R., Gueimonde, M., van Sinderen, D., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0068739 · Cited by 304 · see citing works

Saccharide breakdown and fermentation by the honey bee gut microbiome

Lee, F. J., Rusch, D. B., Stewart, F. J., Mattila, H. R., & Newton, I. L. G. (2014) · Environmental Microbiology · doi:10.1111/1462-2920.12526 · Cited by 290 · see citing works

The effects of dietary fibre addition on the quality of common cereal products

Foschia, M., Peressini, D., Sensidoni, A., & Brennan, C. S. (2013) · Journal of Cereal Science · doi:10.1016/j.jcs.2013.05.010 · Cited by 276 · see citing works

Genomic Encyclopedia of Type Strains of the Genus Bifidobacterium

Milani, C., Lugli, G. A., Duranti, S., Turroni, F., Bottacini, F., Mangifesta, M., Sánchez, B., Viappiani, A., Mancabelli, L., Taminiau, B., et al. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.02308-14 · Cited by 248 · see citing works

Host–microbe interactions that facilitate gut colonization by commensal bifidobacteria

Ventura, M., Turroni, F., Motherway, M. O., MacSharry, J. A., & van Sinderen, D. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.07.002 · Cited by 196 · see citing works

Human milk and related oligosaccharides as prebiotics

Barile, D., & Rastall, R. A. (2013) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2013.01.008 · Cited by 193 · see citing works

Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium

Egan, M., Motherway, M. O., Kilcoyne, M., Kane, M., Joshi, L., Ventura, M., & van Sinderen, D. (2014) · BMC Microbiology · doi:10.1186/s12866-014-0282-7 · Cited by 192 · see citing works

An exo-α-sialidase from bifidobacteria involved in the degradation of sialyloligosaccharides in human milk and intestinal glycoconjugates

Kiyohara, M., Tanigawa, K., Chaiwangsri, T., Katayama, T., Ashida, H., & Yamamoto, K. (2010) · Glycobiology · doi:10.1093/glycob/cwq175 · Cited by 146 · see citing works

Method for milk oligosaccharide profiling by 2-aminobenzamide labeling and hydrophilic interaction chromatography

Mariño, K. V., Lane, J. A., Abrahams, J. L., Struwe, W. B., Harvey, D. J., Marotta, M., Hickey, R. M., & Rudd, P. M. (2011) · Glycobiology · doi:10.1093/glycob/cwr067 · Cited by 143 · see citing works

Glycogen and Maltose Utilization by Escherichia coli O157:H7 in the Mouse Intestine

Jones, S. A., Jørgensen, M. J., Chowdhury, F. Z., Rodgers, R., Hartline, J., Leatham, M. P., Struve, C., Krogfelt, K. A., Cohen, P. S., & Conway, T. (2008) · Infection and Immunity · doi:10.1128/iai.00096-08 · Cited by 130 · see citing works

Investigation of the Evolutionary Development of the Genus Bifidobacterium by Comparative Genomics

Lugli, G. A., Milani, C., Turroni, F., Duranti, S., Ferrario, C., Viappiani, A., Mancabelli, L., Mangifesta, M., Taminiau, B., Delcenserie, V., et al. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.02004-14 · Cited by 127 · see citing works

Bifidobacterial Enzymes Involved in the Metabolism of Human Milk Oligosaccharides

Kitaoka, M. (2012) · Advances in Nutrition · doi:10.3945/an.111.001420 · Cited by 118 · see citing works

Genomics as a means to understand bacterial phylogeny and ecological adaptation: the case of bifidobacteria

Ventura, M., Canchaya, C. A., Fitzgerald, G. F., Gupta, R. S., & van Sinderen, D. (2006) · Antonie van Leeuwenhoek · doi:10.1007/s10482-006-9122-6 · Cited by 111 · see citing works

Glycogen with short average chain length enhances bacterial durability

Wang, L., & Wise, M. J. (2011) · Die Naturwissenschaften · doi:10.1007/s00114-011-0832-x · Cited by 104 · see citing works

Insights into glycogen metabolism in Lactobacillus acidophilus: impact on carbohydrate metabolism, stress tolerance and gut retention

Goh, Y. J., & Klaenhammer, T. R. (2014) · Microbial Cell Factories · doi:10.1186/s12934-014-0094-3 · Cited by 104 · see citing works

Glycogen metabolism loss: a common marker of parasitic behaviour in bacteria?

Henrissat, B., Deleury, E., & Coutinho, P. M. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(02)02734-8 · Cited by 98 · see citing works

Online Resource 2

Gross, A., Guy, O., Posmanik, R., Fine, P., & Nejidat, A. (2012) · Cited by 14 · see citing works

The first microbial colonizers of the human gut: composition, activities, and health implications of the infant gut microbiota

Milani, C., Duranti, S., Bottacini, F., Casey, E., Turroni, F., Mahony, J., Belzer, C., Delgado Palacio, S., Arboleya Montes, S., Mancabelli, L., et al. (2017) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.00036-17 · Cited by 1,950 · see citing works

Bifidobacteria and Their Role as Members of the Human Gut Microbiota

O’Callaghan, A. A., & van Sinderen, D. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00925 · Cited by 1,108 · see citing works

Actinobacteria: A relevant minority for the maintenance of gut homeostasis

Binda, C., Lopetuso, L. R., Rizzatti, G., Gibiino, G., Cennamo, V., & Gasbarrini, A. (2018) · Digestive and Liver Disease · doi:10.1016/j.dld.2018.02.012 · Cited by 814 · see citing works

Gut microbiome stability and resilience: elucidating the response to perturbations in order to modulate gut health

Fassarella, M., Blaak, E. E., Penders, J., Nauta, A., Smidt, H., & Zoetendal, E. G. (2020) · Gut · doi:10.1136/gutjnl-2020-321747 · Cited by 781 · see citing works

Genomic characterization of the uncultured Bacteroidales family S24-7 inhabiting the guts of homeothermic animals

Ormerod, K. L., Wood, D., Lachner, N., Gellatly, S. L., Daly, J. N., Parsons, J. D., Dal’Molin, C. G. D. O., Palfreyman, R. W., Nielsen, L. K., Cooper, M. A., et al. (2016) · Microbiome · doi:10.1186/s40168-016-0181-2 · Cited by 675 · see citing works

The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation

Hiippala, K., Jouhten, H., Ronkainen, A., Hartikainen, A., Kainulainen, V., Jalanka, J., & Satokari, R. M. (2018) · Nutrients · doi:10.3390/nu10080988 · Cited by 599 · see citing works

Polysaccharide Degradation by the Intestinal Microbiota and Its Influence on Human Health and Disease

Cockburn, D. W., & Koropatkin, N. M. (2016) · Journal of Molecular Biology · doi:10.1016/j.jmb.2016.06.021 · Cited by 542 · see citing works

The gut microbiota influences anticancer immunosurveillance and general health

Routy, B., Gopalakrishnan, V., Daillère, R., Zitvogel, L., Wargo, J. A., & Kroemer, G. (2018) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-018-0006-2 · Cited by 523 · see citing works

Bifidobacteria and Their Health-Promoting Effects

Hidalgo-Cantabrana, C., Delgado, S., Ruiz, L., Ruas-Madiedo, P., Sánchez, B., & Margolles, A. (2017) · Microbiology Spectrum · doi:10.1128/microbiolspec.bad-0010-2016 · Cited by 490 · see citing works

Breast milk-derived human milk oligosaccharides promote Bifidobacterium interactions within a single ecosystem

Lawson, M. A., O’Neill, I. J., Kujawska, M., Javvadi, S. G., Wijeyesekera, A., Flegg, Z., Chalklen, L., & Hall, L. J. (2019) · The ISME Journal · doi:10.1038/s41396-019-0553-2 · Cited by 369 · see citing works

Division of labor in honey bee gut microbiota for plant polysaccharide digestion

Zheng, H., Perreau, J. M., Powell, J. E., Han, B., Zhang, Z., Kwong, W. K., Tringe, S. G., & Moran, N. A. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1916224116 · Cited by 358 · see citing works

Human milk oligosaccharides: Shaping the infant gut microbiota and supporting health

Walsh, C., Lane, J. A., van Sinderen, D., & Hickey, R. M. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.104074 · Cited by 355 · see citing works

Bifidobacterium mechanisms of immune modulation and tolerance

Gavzy, S. J., Kensiski, A., Lee, Z. L., Mongodin, E. F., Ma, B., & Bromberg, J. S. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2291164 · Cited by 375 · see citing works

Bifidobacteria and Their Molecular Communication with the Immune System

Ruíz, L., Delgado, S., Ruas‐Madiedo, P., Sánchez, B., & Margollés, A. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02345 · Cited by 329 · see citing works

Maternal inheritance of bifidobacterial communities and bifidophages in infants through vertical transmission

Duranti, S., Lugli, G. A., Mancabelli, L., Armanini, F., Turroni, F., James, K., Ferretti, P., Gorfer, V., Ferrario, C., Milani, C., et al. (2017) · Microbiome · doi:10.1186/s40168-017-0282-6 · Cited by 327 · see citing works

Biochemistry of complex glycan depolymerisation by the human gut microbiota

Ndeh, D. A., & Gilbert, H. J. (2018) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuy002 · Cited by 285 · see citing works

Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways

Engevik, M. A., Luk, B., Chang‐Graham, A. L., Hall, A., Herrmann, B. I., Ruan, W. H., Endres, B. T., Shi, Z., Garey, K. W., Hyser, J. M., et al. (2019) · mBio · doi:10.1128/mbio.01087-19 · Cited by 271 · see citing works

Glycan Utilization and Cross-Feeding Activities by Bifidobacteria

Turroni, F., Milani, C., Duranti, S., Mahony, J., van Sinderen, D., & Ventura, M. (2018) · Trends in Microbiology · doi:10.1016/j.tim.2017.10.001 · Cited by 263 · see citing works

Identification of universal gut microbial biomarkers of common human intestinal diseases by meta-analysis

Mancabelli, L., Milani, C., Lugli, G. A., Turroni, F., Cocconi, D., van Sinderen, D., & Ventura, M. (2017) · FEMS Microbiology Ecology · doi:10.1093/femsec/fix153 · Cited by 240 · see citing works

Genomics of the Genus Bifidobacterium Reveals Species-Specific Adaptation to the Glycan-Rich Gut Environment

Milani, C., Turroni, F., Duranti, S., Lugli, G. A., Mancabelli, L., Ferrario, C., van Sinderen, D., & Ventura, M. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.03500-15 · Cited by 225 · see citing works

Gut microbiota composition and Clostridium difficile infection in hospitalized elderly individuals: a metagenomic study

Milani, C., Ticinesi, A., Gerritsen, J., Nouvenne, A., Lugli, G. A., Mancabelli, L., Turroni, F., Duranti, S., Mangifesta, M., Viappiani, A., et al. (2016) · Scientific Reports · doi:10.1038/srep25945 · Cited by 216 · see citing works

Bifidobacteria and the infant gut: an example of co-evolution and natural selection

Turroni, F., Milani, C., Duranti, S., Ferrario, C., Lugli, G. A., Mancabelli, L., van Sinderen, D., & Ventura, M. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2672-0 · Cited by 205 · see citing works

Gut microbiota modulation with long-chain corn bran arabinoxylan in adults with overweight and obesity is linked to an individualized temporal increase in fecal propionate

Nguyen, N. K., Deehan, E. C., Zhang, Z., Jin, M., Baskota, N., Pérez-Muñoz, M. E., Cole, J. L., Tunçil, Y. E., Seethaler, B., Wang, T., et al. (2020) · Microbiome · doi:10.1186/s40168-020-00887-w · Cited by 192 · see citing works

The Akkermansia muciniphila is a gut microbiota signature in psoriasis

Tan, L., Zhao, S., Zhu, W., Wu, L., Li, J., Shen, M., Li, L., Chen, X., & Peng, C. (2017) · Experimental Dermatology · doi:10.1111/exd.13463 · Cited by 189 · see citing works

Transporters of glucose and other carbohydrates in bacteria

Jeckelmann, J.-M., & Erni, B. (2020) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-020-02379-0 · Cited by 184 · see citing works

Insights into endogenous Bifidobacterium species in the human gut microbiota during adulthood

Derrien, M., Turroni, F., Ventura, M., & van Sinderen, D. (2022) · Trends in Microbiology · doi:10.1016/j.tim.2022.04.004 · Cited by 183 · see citing works

Age-Related Changes in the Composition of Gut Bifidobacterium Species

Kato, K., Odamaki, T., Mitsuyama, E., Sugahara, H., Xiao, J.-Z., & Osawa, R. (2017) · Current Microbiology · doi:10.1007/s00284-017-1272-4 · Cited by 180 · see citing works

Ability of bifidobacteria to metabolize chitin-glucan and its impact on the gut microbiota

Alessandri, G., Milani, C., Duranti, S., Mancabelli, L., Ranjanoro, T., Modica, S., Carnevali, L., Statello, R., Bottacini, F., Turroni, F., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-42257-z · Cited by 178 · see citing works

Mechanistic Insights Into the Cross-Feeding of Ruminococcus gnavus and Ruminococcus bromii on Host and Dietary Carbohydrates

Crost, E. H., Gall, G. L., Gomez, J. A. L., Mukhopadhya, I., Flint, H. J., & Juge, N. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.02558 · Cited by 169 · see citing works

Resistant starch, microbiome, and precision modulation

Dobranowski, P., & Stintzi, A. P. (2021) · Gut Microbes · doi:10.1080/19490976.2021.1926842 · Cited by 163 · see citing works

Mucin Cross-Feeding of Infant Bifidobacteria and Eubacterium hallii

Bunešová, V., Lacroix, C., & Schwab, C. (2017) · Microbial Ecology · doi:10.1007/s00248-017-1037-4 · Cited by 149 · see citing works

Cross-feeding modulates antibiotic tolerance in bacterial communities

Adamowicz, E. M., Flynn, J. M., Hunter, R. C., & Harcombe, W. R. (2018) · The ISME Journal · doi:10.1038/s41396-018-0212-z · Cited by 142 · see citing works

The genus Bifidobacterium : from genomics to functionality of an important component of the mammalian gut microbiota

Alessandri, G., van Sinderen, D., & Ventura, M. (2021) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2021.03.006 · Cited by 147 · see citing works

Rational use of prebiotics for gut microbiota alterations: Specific bacterial phylotypes and related mechanisms

Wang, S., Xiao, Y., Tian, F., Zhao, J., Zhang, H., Zhai, Q., & Chen, W. (2020) · Journal of Functional Foods · doi:10.1016/j.jff.2020.103838 · Cited by 146 · see citing works

Bifidobacterium bifidum: A Key Member of the Early Human Gut Microbiota

Turroni, F., Duranti, S., Milani, C., Lugli, G. A., van Sinderen, D., & Ventura, M. (2019) · Microorganisms · doi:10.3390/microorganisms7110544 · Cited by 140 · see citing works

Bifidobacterial Dialogue With Its Human Host and Consequent Modulation of the Immune System

Alessandri, G., Ossiprandi, M. C., MacSharry, J. A., van Sinderen, D., & Ventura, M. (2019) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02348 · Cited by 128 · see citing works

Milk Glycans and Their Interaction with the Infant-Gut Microbiota

Kirmiz, N., Robinson, R. C., Shah, I. M., Barile, D., & Mills, D. A. (2018) · Annual Review of Food Science and Technology · doi:10.1146/annurev-food-030216-030207 · Cited by 123 · see citing works

Galacto-oligosaccharides as infant prebiotics: production, application, bioactive activities and future perspectives

Ambrogi, V., Bottacini, F., Cao, L., Kuipers, B. J. H., Schoterman, M. H. C., & van Sinderen, D. (2021) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2021.1953437 · Cited by 121 · see citing works

Unveiling bifidobacterial biogeography across the mammalian branch of the tree of life

Milani, C., Mangifesta, M., Mancabelli, L., Lugli, G. A., James, K., Duranti, S., Turroni, F., Ferrario, C., Ossiprandi, M. C., van Sinderen, D., et al. (2017) · The ISME Journal · doi:10.1038/ismej.2017.138 · Cited by 117 · see citing works

Functional oligosaccharide fermentation in the gut: Improving intestinal health and its determinant factors-A review

Zhang, N., Jin, M., Wang, K., Zhang, Z., Shah, N. P., & Wei, H. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.119043 · Cited by 123 · see citing works

Evaluation of genetic diversity among strains of the human gut commensal Bifidobacterium adolescentis

Duranti, S., Milani, C., Lugli, G. A., Mancabelli, L., Turroni, F., Ferrario, C., Mangifesta, M., Viappiani, A., Sánchez, B., Margollés, A., et al. (2016) · Scientific Reports · doi:10.1038/srep23971 · Cited by 116 · see citing works

Intestinal microbiota are involved in the immunomodulatory activities of longan polysaccharide

Zhang, J., Yang, G., Wen, Y., Liu, S., Li, C., Yang, R., & Li, W. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201700466 · Cited by 106 · see citing works

Insights into the reason of Human-Residential Bifidobacteria (HRB) being the natural inhabitants of the human gut and their potential health-promoting benefits

Wong, C. B., Odamaki, T., & Xiao, J. (2020) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuaa010 · Cited by 106 · see citing works

Glycan utilisation system in Bacteroides and Bifidobacteria and their roles in gut stability and health

Singh, R. P. (2019) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-019-10012-z · Cited by 106 · see citing works

Role of the gut microbiota in nutrient competition and protection against intestinal pathogen colonization

Horrocks, V., King, O. G., Yip, A. Y. G., Marques, I. M., & McDonald, J. A. K. (2023) · Microbiology · doi:10.1099/mic.0.001377 · Cited by 104 · see citing works

Prevalence of antibiotic resistance genes among human gut-derived bifidobacteria

Duranti, S., Lugli, G. A., Mancabelli, L., Turroni, F., Milani, C., Mangifesta, M., Ferrario, C., Anzalone, R., Viappiani, A., van Sinderen, D., et al. (2017) · Applied and Environmental Microbiology · doi:10.1128/aem.02894-16 · Cited by 103 · see citing works

Communal living: glycan utilization by the human gut microbiota

Briggs, J. A., Grondin, J. M., & Brumer, H. (2020) · Environmental Microbiology · doi:10.1111/1462-2920.15317 · Cited by 103 · see citing works

Comparative genomic and phylogenomic analyses of the Bifidobacteriaceae family

Lugli, G. A., Milani, C., Turroni, F., Duranti, S., Mancabelli, L., Mangifesta, M., Ferrario, C., Modesto, M., Mattarelli, P., Killer, J., et al. (2017) · BMC Genomics · doi:10.1186/s12864-017-3955-4 · Cited by 100 · see citing works

Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients

Bonfrate, L., Palo, D. M. D., Celano, G., Albert, A., Vitellio, P., Angelis, M. D., Gobbetti, M., & Portincasa, P. (2020) · European Journal of Clinical Investigation · doi:10.1111/eci.13201 · Cited by 100 · see citing works

Gene-trait matching across the Bifidobacterium longum pan-genome reveals considerable diversity in carbohydrate catabolism among human infant strains

Arboleya, S., Bottacini, F., Motherway, M. O., Ryan, C. A., Ross, R. P., van Sinderen, D., & Stanton, C. (2018) · BMC Genomics · doi:10.1186/s12864-017-4388-9 · Cited by 92 · see citing works

Flexibility of Gut Microbiota in Ageing Individuals during Dietary Fiber Long‐Chain Inulin Intake

Kiewiet, M. B. G., Elderman, M. E., Aidy, S. E., Burgerhof, J. G. M., Visser, H., Vaughan, E. E., Faas, M. M., & de Vos, P. (2020) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202000390 · Cited by 92 · see citing works

Prebiotic Galactooligosaccharide Metabolism by Probiotic Lactobacilli and Bifidobacteria

Thongaram, T., Hoeflinger, J. L., Chow, J., & Miller, M. J. (2017) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.7b00851 · Cited by 89 · see citing works

Significance of fucose in intestinal health and disease

Garber, J. M., Hennet, T., & Szymanski, C. M. (2021) · Molecular Microbiology · doi:10.1111/mmi.14681 · Cited by 85 · see citing works

Microbial collaborations and conflicts: unraveling interactions in the gut ecosystem

Wang, S., Mu, L., Yu, C. H. A., He, Y., Hu, X., Jiao, Y., Xu, Z., You, S., Liu, S.-L., & Bao, H. (2023) · Gut Microbes · doi:10.1080/19490976.2023.2296603 · Cited by 86 · see citing works

A Bifidobacterial pilus‐associated protein promotes colonic epithelial proliferation

Motherway, M. O., Houston, A. M., O'Callaghan, G. P., Reunanen, J., O’Brien, F., O’Driscoll, T., Casey, P. G., de Vos, W. M., van Sinderen, D., & Shanahan, F. (2018) · Molecular Microbiology · doi:10.1111/mmi.14155 · Cited by 80 · see citing works

Prebiotic Potential of Dietary Beans and Pulses and Their Resistant Starch for Aging-Associated Gut and Metabolic Health

Kadyan, S., Sharma, A., Arjmandi, B. H., Singh, P. R., & Nagpal, R. (2022) · Nutrients · doi:10.3390/nu14091726 · Cited by 78 · see citing works

The Bifidogenic Effect Revisited—Ecology and Health Perspectives of Bifidobacterial Colonization in Early Life

Kumar, H., Collado, M. C., Wopereis, H., Salminen, S., Knol, J., & Roeselers, G. (2020) · Microorganisms · doi:10.3390/microorganisms8121855 · Cited by 80 · see citing works

The sialate O-acetylesterase EstA from gut Bacteroidetes species enables sialidase-mediated cross-species foraging of 9-O-acetylated sialoglycans

Robinson, L. S., Lewis, W. G., & Lewis, A. L. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.769232 · Cited by 76 · see citing works

A Novel Non-Digestible, Carrot-Derived Polysaccharide (cRG-I) Selectively Modulates the Human Gut Microbiota while Promoting Gut Barrier Integrity: An Integrated In Vitro Approach

Van den Abbeele, P., Verstrepen, L., Ghyselinck, J., Albers, R., Marzorati, M., & Mercenier, A. (2020) · Nutrients · doi:10.3390/nu12071917 · Cited by 73 · see citing works

Interactions between dietary fibre and the gut microbiota

Thomson, C. L., García, A. L., & Edwards, C. A. (2021) · Proceedings of The Nutrition Society · doi:10.1017/s0029665121002834 · Cited by 73 · see citing works

<i>Bifidobacterium bifidum</i> and the infant gut microbiota: an intriguing case of microbe‐host co‐evolution

Duranti, S., Lugli, G. A., Milani, C., James, K., Mancabelli, L., Turroni, F., Alessandri, G., Mangifesta, M., Mancino, W., Ossiprandi, M. C., et al. (2019) · Environmental Microbiology · doi:10.1111/1462-2920.14705 · Cited by 72 · see citing works

Serotonin Transporter Deficiency is Associated with Dysbiosis and Changes in Metabolic Function of the Mouse Intestinal Microbiome

Singhal, M., Turturice, B. A., Manzella, C. R., Ranjan, R., Metwally, A. A., Theorell, J. A., Huang, Y. L., Alrefai, W. A., Dudeja, P. K., Finn, P. W., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-38489-8 · Cited by 71 · see citing works

The mannose phosphotransferase system (Man-PTS) - Mannose transporter and receptor for bacteriocins and bacteriophages

Jeckelmann, J.-M., & Erni, B. (2020) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2020.183412 · Cited by 71 · see citing works

Microbiota and Cancer: The Emerging Beneficial Role of Bifidobacteria in Cancer Immunotherapy

Longhi, G., van Sinderen, D., Ventura, M., & Turroni, F. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.575072 · Cited by 71 · see citing works

Synthetic glycans control gut microbiome structure and mitigate colitis in mice

Tolonen, A. C., Beauchemin, N., Bayne, C. F., Li, L., Tan, J., Lee, J., Meehan, B. M., Meisner, J. S., Millet, Y. A., LeBlanc, G., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28856-x · Cited by 70 · see citing works

How microbial glycosyl hydrolase activity in the gut mucosa initiates microbial cross-feeding

Berkhout, M. D., Plugge, C. M., & Belzer, C. (2021) · Glycobiology · doi:10.1093/glycob/cwab105 · Cited by 69 · see citing works

Metagenomic and culturomic analysis of gut microbiota dysbiosis during Clostridium difficile infection

Amrane, S., Hocquart, M., Afouda, P., Kuete, E., Pham, T.-P.-T., Dione, N., Ngom, I. I., Valles, C., Bachar, D., Raoult, D., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-49189-8 · Cited by 66 · see citing works

Molecular strategies for the utilisation of human milk oligosaccharides by infant gut-associated bacteria

Kiely, L. J., Busca, K., Lane, J. A., van Sinderen, D., & Hickey, R. M. (2023) · FEMS Microbiology Reviews · doi:10.1093/femsre/fuad056 · Cited by 63 · see citing works

Transcriptional Regulation of Carbohydrate Utilization Pathways in the Bifidobacterium Genus

Khoroshkin, M., Leyn, S. A., van Sinderen, D., & Rodionov, D. A. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00120 · Cited by 61 · see citing works

Human milk microbiota associated with early colonization of the neonatal gut in Mexican newborns

Corona-Cervantes, K., García‐González, I., Villalobos-Flores, L. E., Hernández-Quiroz, F., Piña-Escobedo, A., Hoyo‐Vadillo, C., Rangel-Calvillo, M. N., & Garcı́a-Mena, J. (2020) · PeerJ · doi:10.7717/peerj.9205 · Cited by 62 · see citing works

Comprehensive Mining and Characterization of CRISPR-Cas Systems in Bifidobacterium

Pan, M., Nethery, M. A., Hidalgo-Cantabrana, C., & Barrangou, R. (2020) · Microorganisms · doi:10.3390/microorganisms8050720 · Cited by 61 · see citing works

Cooperation and Conflict Within the Microbiota and Their Effects On Animal Hosts

Figueiredo, A. R. T., & Kramer, J. (2020) · Frontiers in Ecology and Evolution · doi:10.3389/fevo.2020.00132 · Cited by 61 · see citing works

Modulation of theeps-ome transcription of bifidobacteria through simulation of human intestinal environment

Ferrario, C., Milani, C., Mancabelli, L., Lugli, G. A., Duranti, S., Mangifesta, M., Viappiani, A., Turroni, F., Margollés, A., Ruas‐Madiedo, P., et al. (2016) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiw056 · Cited by 61 · see citing works

Carbohydrate Staple Food Modulates Gut Microbiota of Mongolians in China

Li, J., Hou, Q., Zhang, J., Xu, H., Sun, Z., Menghe, B., & Zhang, H. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00484 · Cited by 58 · see citing works

Human milk oligosaccharide-sharing by a consortium of infant derived Bifidobacterium species

Walsh, C., Lane, J. A., van Sinderen, D., & Hickey, R. M. (2022) · Scientific Reports · doi:10.1038/s41598-022-07904-y · Cited by 56 · see citing works

Inefficient Metabolism of the Human Milk Oligosaccharides Lacto-N-tetraose and Lacto-N-neotetraose Shifts Bifidobacterium longum subsp. infantis Physiology

Özcan, E., & Sela, D. A. (2018) · Frontiers in Nutrition · doi:10.3389/fnut.2018.00046 · Cited by 55 · see citing works

The presence of resistant starch-degrading amylases in Bifidobacterium adolescentis of the human gut

Jung, D.-H., Seo, D., Kim, Y., Chung, W., Nam, Y., & Park, C. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.05.235 · Cited by 55 · see citing works

Probiotics in the New Era of Human Milk Oligosaccharides (HMOs): HMO Utilization and Beneficial Effects of Bifidobacterium longum subsp. infantis M-63 on Infant Health

Wong, C. B., Huang, H., Ning, Y., & Xiao, J. (2024) · Microorganisms · doi:10.3390/microorganisms12051014 · Cited by 56 · see citing works

Prebiotic galactooligosaccharides activate mucin and pectic galactan utilization pathways in the human gut symbiont Bacteroides thetaiotaomicron

van Bueren, A. L., Mulder, M., van Leeuwen, S. S., & Dijkhuizen, L. (2017) · Scientific Reports · doi:10.1038/srep40478 · Cited by 55 · see citing works

Different physiological properties of human-residential and non-human-residential bifidobacteria in human health

Wong, C. B., Sugahara, H., Odamaki, T., & Xiao, J. (2017) · Beneficial Microbes · doi:10.3920/bm2017.0031 · Cited by 55 · see citing works

Evaluation of Modulatory Activities of Lactobacillus crispatus Strains in the Context of the Vaginal Microbiota

Argentini, C., Fontana, F., Alessandri, G., Lugli, G. A., Mancabelli, L., Ossiprandi, M. C., van Sinderen, D., Ventura, M., Milani, C., & Turroni, F. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.02733-21 · Cited by 53 · see citing works

Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate

Tsenkova, M., Brauer, M., Pozdeev, V. I., Kasakin, M. F., Busi, S. B., Schmoetten, M., Cheung, D., Meyers, M., Rodriguez, F., Gaigneaux, A., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-56678-0 · Cited by 54 · see citing works

Multi-omics Approaches To Decipher the Impact of Diet and Host Physiology on the Mammalian Gut Microbiome

Milani, C., Alessandri, G., Mancabelli, L., Mangifesta, M., Lugli, G. A., Viappiani, A., Longhi, G., Anzalone, R., Duranti, S., Turroni, F., et al. (2020) · Applied and Environmental Microbiology · doi:10.1128/aem.01864-20 · Cited by 54 · see citing works

Gut microbial utilization of xylan and its implication in gut homeostasis and metabolic response

Zhang, B., Zhong, Y., Dong, D., Zheng, Z., & Hu, J. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119271 · Cited by 53 · see citing works

A Human Gut Commensal Ferments Cranberry Carbohydrates To Produce Formate

Özcan, E., Sun, J., Rowley, D. C., & Sela, D. A. (2017) · Applied and Environmental Microbiology · doi:10.1128/aem.01097-17 · Cited by 53 · see citing works

Unveiling Genomic Diversity among Members of the Species Bifidobacterium pseudolongum , a Widely Distributed Gut Commensal of the Animal Kingdom

Lugli, G. A., Duranti, S., Albert, K., Mancabelli, L., Napoli, S., Viappiani, A., Anzalone, R., Longhi, G., Milani, C., Turroni, F., et al. (2019) · Applied and Environmental Microbiology · doi:10.1128/aem.03065-18 · Cited by 53 · see citing works

Bifidobacterium bifidum presents on the cell surface a complex mixture of glucans and galactans with different immunological properties

Speciale, I., Verma, R. P., Lorenzo, F. D., Molinaro, A., Im, S., & Castro, C. D. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.05.006 · Cited by 53 · see citing works

Investigating bifidobacteria and human milk oligosaccharide composition of lactating mothers

Lugli, G. A., Duranti, S., Milani, C., Mancabelli, L., Turroni, F., Alessandri, G., Longhi, G., Anzalone, R., Viappinai, A., Tarracchini, C., et al. (2020) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiaa049 · Cited by 51 · see citing works

Mining genome traits that determine the different gut colonization potential of Lactobacillus and Bifidobacterium species

Xiao, Y., Zhao, J., Zhang, H., Zhai, Q., & Chen, W. (2021) · Microbial Genomics · doi:10.1099/mgen.0.000581 · Cited by 54 · see citing works

Resistant starch utilization by Bifidobacterium, the beneficial human gut bacteria

Jung, D.-H., & Park, C. (2023) · Food Science and Biotechnology · doi:10.1007/s10068-023-01253-w · Cited by 50 · see citing works

Protective properties of combined fungal polysaccharides from Cordyceps sinensis and Ganoderma atrum on colon immune dysfunction

Fan, S., Nie, S., Huang, X., Wang, S., Hu, J., Xie, J.-H., Nie, Q., & Xie, M. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.04.004 · Cited by 50 · see citing works

Succession of Bifidobacterium longum Strains in Response to a Changing Early Life Nutritional Environment Reveals Dietary Substrate Adaptations

Kujawska, M., Rosa, S. L. L., Roger, L. C., Pope, P. B., Hoyles, L., McCartney, A. L., & Hall, L. J. (2020) · iScience · doi:10.1016/j.isci.2020.101368 · Cited by 49 · see citing works

Comparative genomics and genotype-phenotype associations in Bifidobacterium breve

Bottacini, F., Morrissey, R., Esteban-Torres, M., James, K., van Breen, J., Dikareva, E., Egan, M., Lambert, J. M., van Limpt, K., Knol, J., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-28919-4 · Cited by 49 · see citing works

Bifidobacterium bifidum ATCC 15696 and Bifidobacterium breve 24b Metabolic Interaction Based on 2′- O -Fucosyl-Lactose Studied in Steady-State Cultures in a Freter-Style Chemostat

Centanni, M., Ferguson, S. A., Sims, I. M., Biswas, A., & Tannock, G. W. (2019) · Applied and Environmental Microbiology · doi:10.1128/aem.02783-18 · Cited by 49 · see citing works

Integrative genomic reconstruction reveals heterogeneity in carbohydrate utilization across human gut bifidobacteria

Arzamasov, A. A., Rodionov, D. A., Hibberd, M. C., Guruge, J. L., Kent, J. E., Kazanov, M. D., Leyn, S. A., Elane, M. L., Sejane, K., Fürst, A., et al. (2025) · Nature Microbiology · doi:10.1038/s41564-025-02056-x · Cited by 53 · see citing works

Correlation analysis of intestinal flora with hypertension

Liu, J., An, N., Ma, C., Li, X., Zhang, J., Zhu, W., Zhang, Y., & Li, J. (2018) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2018.6500 · Cited by 47 · see citing works

Glycosulfatase-Encoding Gene Cluster in Bifidobacterium breve UCC2003

Egan, M., Jiang, H., Motherway, M. O., Oscarson, S., & van Sinderen, D. (2016) · Applied and Environmental Microbiology · doi:10.1128/aem.02022-16 · Cited by 46 · see citing works

Bifidobacterium longum subsp. longum Remodeled Roseburia and Phosphatidylserine Levels and Ameliorated Intestinal Disorders and liver Metabolic Abnormalities Induced by High-Fat Diet

Wu, T., Sun, M., Liu, R., Sui, W., Zhang, J., Yin, J., Fang, S., Zhu, J., & Zhang, M. (2020) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.0c00717 · Cited by 46 · see citing works

The role of mucin and oligosaccharides via cross-feeding activities by Bifidobacterium: A review

Luo, Y., Xiao, Y., Zhao, J., Zhang, H., Chen, W., & Zhai, Q. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.11.087 · Cited by 45 · see citing works

Cross-feeding interactions between human gut commensals belonging to the Bacteroides and Bifidobacterium genera when grown on dietary glycans

Fernandez-Julia, P., Commane, D. M., van Sinderen, D., & Muñoz-Muñoz, J. (2022) · Microbiome Research Reports · doi:10.20517/mrr.2021.05 · Cited by 45 · see citing works

Genomics of the Genus Bifidobacterium Reveals Species-Specific Adaptation to the Glycan-Rich Gut Environment

Milani, C., Turroni, F., Duranti, S., Lugli, G. A., Mancabelli, L., Ferrario, C., van Sinderen, D., & Ventura, M. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.03500-15 · Cited by 225 · see citing works

Glycan Utilization and Cross-Feeding Activities by Bifidobacteria

Turroni, F., Milani, C., Duranti, S., Mahony, J., van Sinderen, D., & Ventura, M. (2018) · Trends in Microbiology · doi:10.1016/j.tim.2017.10.001 · Cited by 263 · see citing works

Bifidobacteria: Ecology and Coevolution With the Host

Turroni, F., Milani, C., van Sinderen, D., & Ventura, M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805060-6.00012-0 · Cited by 5 · see citing works

Deciphering bifidobacterial-mediated metabolic interactions and their impact on gut microbiota by a multi-omics approach

Turroni, F., Milani, C., Duranti, S., Mancabelli, L., Mangifesta, M., Viappiani, A., Lugli, G. A., Ferrario, C., Gioiosa, L., Ferrarini, A., et al. (2016) · The ISME Journal · doi:10.1038/ismej.2015.236 · Cited by 207 · see citing works

Insights from genomes of representatives of the human gut commensal B ifidobacterium bifidum

Duranti, S., Milani, C., Lugli, G. A., Turroni, F., Mancabelli, L., Sánchez, B., Ferrario, C., Viappiani, A., Mangifesta, M., Mancino, W., et al. (2014) · Environmental Microbiology · doi:10.1111/1462-2920.12743 · Cited by 83 · see citing works