Glial fibrillary acidic protein: From intermediate filament assembly and gliosis to neurobiomarker

Molecular dissection of reactive astrogliosis and glial scar formation

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Glial Fibrillary Acidic Protein: GFAP-Thirty-One Years (1969–2000)

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GFAP in health and disease

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Injury Prevention and Control

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Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention

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Report to Congress on Mild Traumatic Brain Injury in the United States: Steps to Prevent a Serious Public Health Problem

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Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system.

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Citrullination: A posttranslational modification in health and disease

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Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury

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Novel functional roles for enteric glia in the gastrointestinal tract

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Release of Glial Tissue–Specific Proteins After Acute Stroke

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Induction of Glial Fibrillary Acidic Protein Expression in Astrocytes by Nitric Oxide

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GFAP and S100B are biomarkers of traumatic brain injury

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The Tumor Inhibitor and Antiangiogenic Agent Withaferin A Targets the Intermediate Filament Protein Vimentin

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Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention

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GFAP Isoforms in Adult Mouse Brain with a Focus on Neurogenic Astrocytes and Reactive Astrogliosis in Mouse Models of Alzheimer Disease

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GFAP mutations, age at onset, and clinical subtypes in Alexander disease

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Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity

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Alexander Disease

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Immune-Mediated Pore-Forming Pathways Induce Cellular Hypercitrullination and Generate Citrullinated Autoantigens in Rheumatoid Arthritis

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Glial fibrillary acidic protein isoform expression in plaque related astrogliosis in Alzheimer's disease

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GPR37 and GPR37L1 are receptors for the neuroprotective and glioprotective factors prosaptide and prosaposin

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Serum GFAP is a diagnostic marker for glioblastoma multiforme

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Lipopolysaccharide-induced interleukin-6 production is controlled by glycogen synthase kinase-3 and STAT3 in the brain

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Proinflammatory cytokines increase glial fibrillary acidic protein expression in enteric glia

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Molecular cloning and primary structure of human glial fibrillary acidic protein.

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GFAP-BDP as an Acute Diagnostic Marker in Traumatic Brain Injury: Results from the Prospective Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study

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GFAP and its role in Alexander disease

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LPS and IL‐1 differentially activate mouse and human astrocytes: Role of CD14

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Systemic injection of LPS induces region-specific neuroinflammation and mitochondrial dysfunction in normal mouse brain

Noh, H., Jeon, J., & Seo, H. (2014) · Neurochemistry International · doi:10.1016/j.neuint.2014.02.008 · Cited by 203 · see citing works

Serum glial fibrillary acidic protein as a biomarker for intracerebral haemorrhage in patients with acute stroke

Foerch, C. (2005) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.2005.074823 · Cited by 202 · see citing works

Human traumatic brain injury induces autoantibody response against glial fibrillary acidic protein and its breakdown products

Zhang, Z., Zoltewicz, J. S., Mondello, S., Newsom, K. J., Yang, Z., Yang, B., Kobeissy, F., Guingab, J., Glushakova, O., Robicsek, S., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092698 · Cited by 200 · see citing works

Loss of glial fibrillary acidic protein (GFAP) impairs Schwann cell proliferation and delays nerve regeneration after damage

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Enteric <scp>GFAP</scp> expression and phosphorylation in Parkinson's disease

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Glial fibrillary acidic protein (GFAP): modulation by growth factors and its implication in astrocyte differentiation

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Neuronal expression of GFAP in patients with Alzheimer pathology and identification of novel GFAP splice forms

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Serum Brain Biomarker Level, Neurocognitive Performance, and Self-Reported Symptom Changes in Soldiers Repeatedly Exposed to Low-Level Blast: A Breacher Pilot Study

Tate, C. M., Wang, K., Eonta, S. E., et al. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2012.2683 · Cited by 164 · see citing works

Alexander Disease-Associated Glial Fibrillary Acidic Protein Mutations in Mice Induce Rosenthal Fiber Formation and a White Matter Stress Response

Hagemann, T. L., Connor, J. X., & Messing, A. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3260-06.2006 · Cited by 162 · see citing works

Intermediate filament assembly: fibrillogenesis is driven by decisive dimer-dimer interactions

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Distribution of enteric glia and GDNF during gut inflammation

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Adult human subventricular, subgranular, and subpial zones contain astrocytes with a specialized intermediate filament cytoskeleton

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Glial Fibrillary Acidic Protein: Dynamic Property and Regulation by Phosphorylation

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Glial Neuronal Ratio: A Novel Index for Differentiating Injury Type in Patients with Severe Traumatic Brain Injury

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Stress and Traumatic Brain Injury: A Behavioral, Proteomics, and Histological Study

Kwon, S.-K. C., Kövesdi, E., Gyorgy, A. B., Wingo, D., Kamnaksh, A., Walker, J., Long, J. B., & Agoston, D. V. (2011) · Frontiers in Neurology · doi:10.3389/fneur.2011.00012 · Cited by 130 · see citing works

Caspase-Mediated Cleavage of Glial Fibrillary Acidic Protein within Degenerating Astrocytes of the Alzheimer's Disease Brain

Mouser, P. E., Head, E., Ha, K.-H., & Rohn, T. T. (2006) · American Journal Of Pathology · doi:10.2353/ajpath.2006.050798 · Cited by 121 · see citing works

Prostaglandins and Cyclooxygenases in Glial Cells During Brain Inflammation

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Multiple alphaII-spectrin breakdown products distinguish calpain and caspase dominated necrotic and apoptotic cell death pathways

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Acute Exposure to CNTFin VivoInduces Multiple Components of Reactive Gliosis

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S-100 protein, but not calmodulin, binds to the glial fibrillary acidic protein and inhibits its polymerization in a Ca(2+)-dependent manner

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Acute Diagnostic Biomarkers for Spinal Cord Injury: Review of the Literature and Preliminary Research Report

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Glial cell modulators attenuate methamphetamine self-administration in therat

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Traumatic Brain Injuries Sustained in the Afghanistan and Iraq Wars

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A New Splice Variant of Glial Fibrillary Acidic Protein, GFAPε, Interacts with the Presenilin Proteins

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Neuro-glial and systemic mechanisms of pathological responses in rat models of primary blast overpressure compared to “composite” blast

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Release of glial fibrillary acidic protein is related to the neurovascular status in acute ischemic stroke

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Withaferin A Targets Intermediate Filaments Glial Fibrillary Acidic Protein and Vimentin in a Model of Retinal Gliosis

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The glial cell modulator and phosphodiesterase inhibitor, AV411 (Ibudilast), attenuates prime- and stress-induced methamphetamine relapse

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Inflammation and gliosis in neurological diseases – clinical implications

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Glial Cell–Mediated Deterioration and Repair of the Nervous System after Traumatic Brain Injury in a Rat Model as Assessed by Positron Emission Tomography

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Stroke and TGF-β proteins: glial cell line-derived neurotrophic factor and bone morphogenetic protein

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Rapid increase in immunoreactivity to GFAP in astrocytes in vitro induced by acidic pH is mediated by calcium influx and calpain I

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Control of the phosphorylation of the astrocyte marker glial fibrillary acidic protein (GFAP) in the immature rat hippocampus by glutamate and calcium ions: possible key factor in astrocytic plasticity

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Ectonucleotidases in the digestive system: focus on NTPDase3 localization

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Identification and characterization of GFAPκ, a novel glial fibrillary acidic protein isoform

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Axonal and Nonneuronal Cell Responses to Spinal Cord Injury in Mice Lacking Glial Fibrillary Acidic Protein

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Transient modulation of Schwann cell antigens after peripheral nerve transection and subsequent regeneration

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Identification and characterization of citrulline‐modified brain proteins by combining HCD and CID fragmentation

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Regulation of hippocampal neuronal differentiation by the basic helix-loop-helix transcription factors HES-1 and MASH-1

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Retro-Inverso Prosaptide Peptides Retain Bioactivity, Are Stable In Vivo, and Are Blood-Brain Barrier Permeable

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Biomarkers Track Damage after Graded Injury Severity in a Rat Model of Penetrating Brain Injury

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A novel glial fibrillary acidic protein mRNA lacking exon 1

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Serum levels of glial fibrillary acidic protein correlate to tumour volume of high-grade gliomas

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Strategies for Treatment in Alexander Disease

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Neuronal modulation of schwann cell glial fibrillary acidic protein (GFAP)

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Glial fibrillary acidic protein mRNA isotypes: Expression in vitro and in vivo

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Use of Serum Biomarkers to Predict Cerebral Hypoxia after Severe Traumatic Brain Injury

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A Novel Multicenter Preclinical Drug Screening and Biomarker Consortium for Experimental Traumatic Brain Injury: Operation Brain Trauma Therapy

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The role of glial cells in Alzheimer disease: potential therapeutic implications

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Caspase Cleavage of GFAP Produces an Assembly-Compromised Proteolytic Fragment that Promotes Filament Aggregation

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Identification of two N-terminal non-alpha-helical domain motifs important in the assembly of glial fibrillary acidic protein

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A Rehabilomics focused perspective on molecular mechanisms underlying neurological injury, complications, and recovery after severe TBI

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A Brief Overview of Traumatic Brain Injury (TBI) and Post-Traumatic Stress Disorder (PTSD) Within the Department of Defense

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Systemic Administration of Propentofylline, Ibudilast, and (+)-Naltrexone Each Reverses Mechanical Allodynia in a Novel Rat Model of Central Neuropathic Pain

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Drug screening to identify suppressors of GFAP expression

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Papel de la glía en la enfermedad de Alzheimer. Futuras implicaciones terapéuticas

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Serum glial fibrillary acidic protein as a biomarker for differentiating intracerebral hemorrhage and ischemic stroke in patients with symptoms of acute stroke: a systematic review and meta-analysis

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Serum GFAP autoantibody as an ELISA-detectable glioma marker

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