Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

Estimating the global incidence of traumatic brain injury

Dewan, M. C., Rattani, A., Gupta, S., Baticulon, R. E., Hung, Y., Punchak, M. A., Agrawal, A., Adeleye, A. O., Shrime, M. G., Rubiano, A. M., et al. (2018) · Journal of neurosurgery · doi:10.3171/2017.10.jns17352 · Cited by 3,354 · see citing works

Neurofilament light chain as a biomarker in neurological disorders

Gaetani, L., Blennow, K., Calabresi, P., Di Filippo, M., Parnetti, L., & Zetterberg, H. (2019) · Journal of Neurology, Neurosurgery & Psychiatry · doi:10.1136/jnnp-2018-320106 · Cited by 1,334 · see citing works

Biomarkers for neurodegenerative diseases

Hansson, O. (2021) · Nature Medicine · doi:10.1038/s41591-021-01382-x · Cited by 1,159 · see citing works

Indications for Computed Tomography in Patients with Minor Head Injury

Haydel, M. J., Preston, C. A., Mills, T. J., Luber, S., Blaudeau, E., & DeBlieux, P. M. C. (2000) · New England Journal of Medicine · doi:10.1056/nejm200007133430204 · Cited by 1,088 · see citing works

Glial fibrillary acidic protein: From intermediate filament assembly and gliosis to neurobiomarker

Yang, Z., & Wang, K. K. W. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.04.003 · Cited by 1,050 · see citing works

Serum GFAP and UCH-L1 for prediction of absence of intracranial injuries on head CT (ALERT-TBI): a multicentre observational study

Bazarian, J. J., Biberthaler, P., Welch, R. D., Lewis, L. M., Barzo, P., Bogner-Flatz, V., Gunnar Brolinson, P., Büki, A., Chen, J. Y., Christenson, R. H., et al. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30231-x · Cited by 617 · see citing works

Time Course and Diagnostic Accuracy of Glial and Neuronal Blood Biomarkers GFAP and UCH-L1 in a Large Cohort of Trauma Patients With and Without Mild Traumatic Brain Injury

Papa, L., Brophy, G. M., Welch, R. D., Lewis, L. M., Braga, C. F., Tan, C. N., Ameli, N. J., López, M. A., Haeussler, C. A., Giordano, D. M., et al. (2016) · JAMA Neurology · doi:10.1001/jamaneurol.2016.0039 · Cited by 542 · see citing works

Biomarkers of traumatic injury are transported from brain to blood via the glymphatic system.

Plog, B. A., Dashnaw, M. L., Hitomi, E., Peng, W., Liao, Y., Lou, N., Deane, R., & Nedergaard, M. (2015) · The Journal of Neuroscience · doi:10.1523/jneurosci.3742-14.2015 · Cited by 525 · see citing works

Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI)

Maas, A. I. R., Menon, D. K., Steyerberg, E. W., Citerio, G., Lecky, F. E., Manley, G. T., Hill, S., Legrand, V., & Sorgner, A. (2014) · Neurosurgery · doi:10.1227/neu.0000000000000575 · Cited by 512 · see citing works

Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer’s disease

Chatterjee, P., Pedrini, S., Stoops, E., Goozee, K., Villemagne, V. L., Asih, P. R., Verberk, I. M. W., Dave, P., Taddei, K., Sohrabi, H. R., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-020-01137-1 · Cited by 439 · see citing works

Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults: an evidence and consensus-based update

Undén, J., Ingebrigtsen, T., & Romner, B. (2013) · BMC Medicine · doi:10.1186/1741-7015-11-50 · Cited by 437 · see citing works

Acute Biomarkers of Traumatic Brain Injury: Relationship between Plasma Levels of Ubiquitin C-Terminal Hydrolase-L1 and Glial Fibrillary Acidic Protein

Diaz-Arrastia, R., Wang, K. K. W., Papa, L., Sorani, M. D., Yue, J. K., Puccio, A., McMahon, P., Inoue, T., Yuh, E., Lingsma, H. F., et al. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2013.3040 · Cited by 434 · see citing works

Blood Biomarkers for Brain Injury in Concussed Professional Ice Hockey Players

Shahim, P., Tegner, Y., Wilson, D. H., Randall, J., Skillbäck, T. B., Pazooki, D., Kallberg, B., Blennow, K., & Zetterberg, H. (2014) · JAMA Neurology · doi:10.1001/jamaneurol.2014.367 · Cited by 389 · see citing works

Transforming Research and Clinical Knowledge in Traumatic Brain Injury Pilot: Multicenter Implementation of the Common Data Elements for Traumatic Brain Injury

Yue, J. K., Vassar, M. J., Lingsma, H. F., Cooper, S. R., Okonkwo, D. O., Valadka, A. B., Gordon, W. A., Maas, A. I. R., Mukherjee, P., Yuh, E. L., et al. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2013.2970 · Cited by 371 · see citing works

A Manual for the Glasgow Outcome Scale-Extended Interview

Wilson, L., Boase, K., Nelson, L. D., Temkin, N. R., Giacino, J. T., Markowitz, A. J., Maas, A. I. R., Menon, D. K., Teasdale, G. M., & Manley, G. T. (2021) · Journal of Neurotrauma · doi:10.1089/neu.2020.7527 · Cited by 347 · see citing works

Serum neurofilament light protein predicts clinical outcome in traumatic brain injury

Shahim, P., Gren, M., Liman, V., Andreasson, U., Norgren, N., Tegner, Y., Mattsson, N., Andreasen, N., Öst, M., Zetterberg, H., et al. (2016) · Scientific Reports · doi:10.1038/srep36791 · Cited by 336 · see citing works

Elevated levels of serum glial fibrillary acidic protein breakdown products in mild and moderate traumatic brain injury are associated with intracranial lesions and neurosurgical intervention

Papa, L., Lewis, L. M., Falk, J. L., Zhang, Z., Silvestri, S., Giordano, P., Brophy, G. M., Demery, J. A., Dixit, N. K., Ferguson, I., et al. (2012) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2011.08.021 · Cited by 332 · see citing works

A review of the clinical utility of serum S100B protein levels in the assessment of traumatic brain injury

Thelin, E. P., Nelson, D., & Bellander, B. (2016) · Acta Neurochirurgica · doi:10.1007/s00701-016-3046-3 · Cited by 318 · see citing works

Guidelines for the standardization of preanalytic variables for blood‐based biomarker studies in Alzheimer's disease research

O’Bryant, S. E., Gupta, V. B., Henriksen, K., Edwards, M., Jeromin, A., Lista, S., Bazenet, C. E., Soares, H. D., Lovestone, S., Hampel, H. J., et al. (2014) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2014.08.099 · Cited by 290 · see citing works

Serum GFAP as a biomarker for disease severity in multiple sclerosis

Abdelhak, A., Huss, A. M., Kassubek, J., Tumani, H., & Otto, M. (2018) · Scientific Reports · doi:10.1038/s41598-018-33158-8 · Cited by 289 · see citing works

Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study

Czeiter, E., Amrein, K., Gravesteijn, B. Y., Lecky, F. E., Menon, D. K., Mondello, S., Newcombe, V., Richter, S., Steyerberg, E. W., Vyvere, T. V., et al. (2020) · EBioMedicine · doi:10.1016/j.ebiom.2020.102785 · Cited by 281 · see citing works

Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain Injury Dynamics: A Systematic Review

Thelin, E. P., Zeiler, F. A., Ercole, A., Mondello, S., Büki, A., Bellander, B., Helmy, A. E., Menon, D. K., & Nelson, D. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00300 · Cited by 263 · see citing works

Neurofilament light as a biomarker in traumatic brain injury

Shahim, P., Politis, A., van der Merwe, A., Moore, B., Chou, Y., Pham, D. L., Butman, J. A., Diaz-Arrastia, R. R., Gill, J., Brody, D. L., et al. (2020) · Neurology · doi:10.1212/wnl.0000000000009983 · Cited by 261 · see citing works

Biokinetic Analysis of Ubiquitin C-Terminal Hydrolase-L1 (UCH-L1) in Severe Traumatic Brain Injury Patient Biofluids

Brophy, G. M., Mondello, S., Papa, L., Robicsek, S. A., Gabrielli, A., Tepas, J. J., Büki, A., Robertson, C. S., Tortella, F. C., Hayes, R. L., et al. (2011) · Journal of Neurotrauma · doi:10.1089/neu.2010.1564 · Cited by 247 · see citing works

Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI cohort: an observational cohort study

Korley, F. K., Jain, S., Sun, X., Puccio, A. M., Yue, J. K., Gardner, R. C., Wang, K., Okonkwo, D. O., Yuh, E. L., Mukherjee, P., et al. (2022) · The Lancet Neurology · doi:10.1016/s1474-4422(22)00256-3 · Cited by 247 · see citing works

Serum levels of ubiquitin C-terminal hydrolase distinguish mild traumatic brain injury from trauma controls and are elevated in mild and moderate traumatic brain injury patients with intracranial lesions and neurosurgical intervention

Papa, L., Lewis, L. M., Silvestri, S., Falk, J. L., Giordano, P., Brophy, G. M., Demery, J. A., Liu, M. C., Mo, J., Akinyi, L., et al. (2012) · The Journal of Trauma: Injury, Infection, and Critical Care · doi:10.1097/ta.0b013e3182491e3d · Cited by 243 · see citing works

Validation of Analytic Methods for Biomarkers Used in Drug Development

Chau, C. H., Rixe, O., McLeod, H. L., & Figg, W. D. (2008) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-07-4535 · Cited by 241 · see citing works

Association between plasma GFAP concentrations and MRI abnormalities in patients with CT-negative traumatic brain injury in the TRACK-TBI cohort: a prospective multicentre study

Yue, J. K., Yuh, E. L., Korley, F. K., Winkler, E. A., Sun, X., Puffer, R. C., Deng, H., Choy, W., Chandra, A., Taylor, S. R., et al. (2019) · The Lancet Neurology · doi:10.1016/s1474-4422(19)30282-0 · Cited by 240 · see citing works

Time course and diagnostic utility of NfL, tau, GFAP, and UCH-L1 in subacute and chronic TBI

Shahim, P., Politis, A., van der Merwe, A., Moore, B., Ekanayake, V., Lippa, S. M., Chou, Y., Pham, D. L., Butman, J. A., Diaz-Arrastia, R. R., et al. (2020) · Neurology · doi:10.1212/wnl.0000000000009985 · Cited by 236 · see citing works

Renal function is associated with blood neurofilament light chain level in older adults

Akamine, S., Marutani, N., Kanayama, D., Gotoh, S., Maruyama, R., Yanagida, K., Sakagami, Y., Mori, K., Adachi, H., Kozawa, J., et al. (2020) · Scientific Reports · doi:10.1038/s41598-020-76990-7 · Cited by 213 · see citing works

Intracellular transport and regulation of transcytosis across the blood–brain barrier

Villaseñor, R., Lampe, J., Schwaninger, M., & Collin, L. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2982-x · Cited by 213 · see citing works

Accuracy of Mild Traumatic Brain Injury Diagnosis

Powell, J. M., Ferraro, J. V., DIKMEN, S. S., Temkin, N. R., & Bell, K. R. (2008) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2007.12.035 · Cited by 206 · see citing works

GFAP Out-Performs S100β in Detecting Traumatic Intracranial Lesions on Computed Tomography in Trauma Patients with Mild Traumatic Brain Injury and Those with Extracranial Lesions

Papa, L., Silvestri, S., Brophy, G. M., Giordano, P., Falk, J. L., Braga, C. F., Tan, C. N., Ameli, N. J., Demery, J. A., Dixit, N. K., et al. (2014) · Journal of Neurotrauma · doi:10.1089/neu.2013.3245 · Cited by 206 · see citing works

Increases of Plasma Levels of Glial Fibrillary Acidic Protein, Tau, and Amyloid β up to 90 Days after Traumatic Brain Injury

Bogoslovsky, T., Wilson, D. H., Chen, Y., Hanlon, D., Gill, J., Jeromin, A., Song, L., Moore, C., Gong, Y., Kenney, K., et al. (2017) · Journal of Neurotrauma · doi:10.1089/neu.2015.4333 · Cited by 203 · see citing works

Axonal marker neurofilament light predicts long-term outcomes and progressive neurodegeneration after traumatic brain injury

Graham, N., Zimmerman, K. A., Moro, F., Heslegrave, A., Maillard, S. A., Bernini, A., Miroz, J., Donat, C. K., Lopez, M. Y., Bourke, N., et al. (2021) · Science Translational Medicine · doi:10.1126/scitranslmed.abg9922 · Cited by 198 · see citing works

Establishment of reference values for plasma neurofilament light based on healthy individuals aged 5–90 years

Simrén, J., Andréasson, U., Gobom, J., Suárez‐Calvet, M., Borroni, B., Gillberg, C., Nyberg, L. H., Ghidoni, R., Fernell, E., Johnson, M., et al. (2022) · Brain Communications · doi:10.1093/braincomms/fcac174 · Cited by 196 · see citing works

Assessment of Follow-up Care After Emergency Department Presentation for Mild Traumatic Brain Injury and Concussion

Seabury, S. A., Gaudette, É., Goldman, D. P., Markowitz, A. J., Brooks, J. C., McCrea, M., Okonkwo, D. O., Manley, G. T., and the TRACK-TBI Investigators, Adeoye, O. M., et al. (2018) · JAMA Network Open · doi:10.1001/jamanetworkopen.2018.0210 · Cited by 189 · see citing works

Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity

Högel, H., Rissanen, E., Barro, C., Matilainen, M., Nylund, M., Kühle, J., & Airas, L. M. (2018) · Multiple Sclerosis Journal · doi:10.1177/1352458518819380 · Cited by 167 · see citing works

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes

McCrea, M., Broglio, S. P., McAllister, T. W., Gill, J., Giza, C. C., Huber, D. L., Harezlak, J., Cameron, K. L., Houston, M. N., McGinty, G. T., et al. (2020) · JAMA Network Open · doi:10.1001/jamanetworkopen.2019.19771 · Cited by 166 · see citing works

Utility of neuron-specific enolase in traumatic brain injury; relations to S100B levels, outcome, and extracranial injury severity

Thelin, E. P., Jeppsson, E., Frostell, A., Svensson, M. A., Mondello, S., Bellander, B., & Nelson, D. (2016) · Critical Care · doi:10.1186/s13054-016-1450-y · Cited by 163 · see citing works

Point-of-Care Platform Blood Biomarker Testing of Glial Fibrillary Acidic Protein versus S100 Calcium-Binding Protein B for Prediction of Traumatic Brain Injuries: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study

Okonkwo, D. O., Puffer, R. C., Puccio, A. M., Yuh, E. L., Yue, J. K., Diaz-Arrastia, R. R., Korley, F. K., Wang, K., Sun, X., Taylor, S. R., et al. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2020.7140 · Cited by 157 · see citing works

Validation of the Scandinavian guidelines for initial management of minimal, mild and moderate traumatic brain injury in adults

Undén, L., Calcagnile, O., Undén, J., Reinstrup, P., & Bazarian, J. (2015) · BMC Medicine · doi:10.1186/s12916-015-0533-y · Cited by 155 · see citing works

Assessing the Severity of Traumatic Brain Injury—Time for a Change?

Tenovuo, O. S., Diaz-Arrastia, R. R., Goldstein, L. E., Sharp, D. J., van der Naalt, J., & Zasler, N. D. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10010148 · Cited by 152 · see citing works

Common Data Elements for Traumatic Brain Injury: Recommendations From the Biospecimens and Biomarkers Working Group

Manley, G. T., Diaz-Arrastia, R. R., Brophy, M. T., Engel, D. C., Goodman, C. J., Gwinn, K. A., Veenstra, T. D., Ling, G. S. F., Ottens, A. K., Tortella, F. C., et al. (2010) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2010.05.018 · Cited by 151 · see citing works

An international review of head and spinal cord injuries in alpine skiing and snowboarding

Ackery, A., Hagel, B. E., Provvidenza, C. F., & Tator, C. (2007) · Injury Prevention · doi:10.1136/ip.2007.017285 · Cited by 150 · see citing works

Glial fibrillary acidic protein as a biomarker in severe traumatic brain injury patients: a prospective cohort study

Lei, J., Gao, G., Feng, J., Jin, Y., Wang, C., Mao, Q., & Jiang, J. (2015) · Critical Care · doi:10.1186/s13054-015-1081-8 · Cited by 147 · see citing works

A prospective cluster-randomized trial to implement the Canadian CT Head Rule in emergency departments

Stiell, I. G., Clement, C. M., Grimshaw, J., Brison, R. J., Rowe, B. H., Lee, J. S., Shah, A. R., Brehaut, J., Holroyd, B. R., Schull, M. J., et al. (2010) · Canadian Medical Association Journal · doi:10.1503/cmaj.091974 · Cited by 146 · see citing works

Neurofilament Light Chain as a Biomarker, and Correlation with Magnetic Resonance Imaging in Diagnosis of CNS-Related Disorders

Alirezaei, Z., Pourhanifeh, M. H., Borran, S., Nejati, M., Mirzaei, H., & Hamblin, M. R. (2020) · Molecular Neurobiology · doi:10.1007/s12035-019-01698-3 · Cited by 142 · see citing works

The S100B Protein: A Multifaceted Pathogenic Factor More Than a Biomarker

Michetti, F., Clementi, M. E., Liddo, R. D., Valeriani, F., Ria, F., Rende, M., Sante, G. D., & Spica, V. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24119605 · Cited by 134 · see citing works

Factors influencing serum neurofilament light chain levels in normal aging

Koini, M., Pirpamer, L., Hofer, E., Buchmann, A., Pinter, D., Ropele, S., Enzinger, C., Benkert, P., Leppert, D., Kühle, J., et al. (2021) · Aging · doi:10.18632/aging.203790 · Cited by 134 · see citing works

Predictive value of S-100 protein for prognosis in patients with moderate and severe traumatic brain injury: systematic review and meta-analysis

Mercier, É., Boutin, A., Lauzier, F., Fergusson, D. A., Simard, J.-F., Zarychanski, R., Moore, L., McIntyre, L., Archambault, P. M., Lamontagne, F., et al. (2013) · BMJ · doi:10.1136/bmj.f1757 · Cited by 133 · see citing works

S100B Is an Important Outcome Predictor in Traumatic Brain Injury

Thelin, E. P., Johannesson, L., Nelson, D., & Bellander, B. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2012.2553 · Cited by 130 · see citing works

Extracellular matrix and traumatic brain injury

George, N., & Geller, H. M. (2018) · Journal of Neuroscience Research · doi:10.1002/jnr.24151 · Cited by 128 · see citing works

The canadian CT head rule study for patients with minor head injury: Rationale, objectives, and methodology for phase I (derivation)

Stiell, I. G., Lesiuk, H. J., Wells, G. A., McKnight, R. D., Brison, R. J., Clement, C. M., Eisenhauer, M. A., Greenberg, G. H., MacPhail, I., Reardon, M., et al. (2001) · Annals of Emergency Medicine · doi:10.1067/mem.2001.116796 · Cited by 126 · see citing works

Recommendation for the review of biological reference intervals in medical laboratories

Henny, J., Vassault, A., Boursier, G., Vukasovic, I., Mesko Brguljan, P., Lohmander, M., Ghita, I., Andreu, F. A. B., Kroupis, C., Sprongl, L., et al. (2016) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2016-0793 · Cited by 119 · see citing works

The multifaceted role of neurofilament light chain protein in non-primary neurological diseases

Abu‐Rumeileh, S., Abdelhak, A., Foschi, M., D’Anna, L., Russo, M., Steinacker, P., Kühle, J., Tumani, H., Blennow, K., & Otto, M. (2022) · Brain · doi:10.1093/brain/awac328 · Cited by 119 · see citing works

Incremental prognostic value of acute serum biomarkers for functional outcome after traumatic brain injury (CENTER-TBI): an observational cohort study

Helmrich, I. R., Czeiter, E., Amrein, K., Büki, A., Lingsma, H. F., Menon, D. K., Mondello, S., Steyerberg, E. W., von Steinbüchel, N., Wang, K., et al. (2022) · The Lancet Neurology · doi:10.1016/s1474-4422(22)00218-6 · Cited by 109 · see citing works

Accuracy of a rapid glial fibrillary acidic protein/ubiquitin carboxyl‐terminal hydrolase L1 test for the prediction of intracranial injuries on head computed tomography after mild traumatic brain injury

Bazarian, J. J., Welch, R. D., Caudle, K. L., Jeffrey, C. A., Chen, J. Y., Chandran, R., McCaw, T., Datwyler, S. A., Zhang, H., & McQuiston, B. (2021) · Academic Emergency Medicine · doi:10.1111/acem.14366 · Cited by 106 · see citing works

Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 as Outcome Predictors in Traumatic Brain Injury

Takala, R. S. K., Posti, J. P., Runtti, H., Newcombe, V. F., Outtrim, J., Katila, A. J., Frantzén, J., Ala-Seppälä, H., Kyllönen, A., Maanpää, H.-R., et al. (2016) · World Neurosurgery · doi:10.1016/j.wneu.2015.10.066 · Cited by 105 · see citing works

Pediatric Concentrations of S100B Protein in Blood: Age- and Sex-related Changes

Gazzolo, D., Michetti, F., Bruschettini, M., Marchese, N., Lituania, M., Mangraviti, S., Pedrazzi, E., & Bruschettini, P. (2003) · Clinical Chemistry · doi:10.1373/49.6.967 · Cited by 104 · see citing works

The Levels of Glial Fibrillary Acidic Protein and Ubiquitin C-Terminal Hydrolase-L1 During the First Week After a Traumatic Brain Injury

Posti, J. P., Takala, R. S. K., Liedes, H., Newcombe, V., Outtrim, J. G., Katila, A. J., Frantzén, J., Ala-Seppälä, H. M., Coles, J., Hossain, I., et al. (2016) · Neurosurgery · doi:10.1227/neu.0000000000001226 · Cited by 103 · see citing works

Evaluating glial and neuronal blood biomarkers GFAP and UCH-L1 as gradients of brain injury in concussive, subconcussive and non-concussive trauma: a prospective cohort study

Papa, L., Zonfrillo, M. R., Welch, R. D., Lewis, L. M., Braga, C. F., Tan, C. N., Ameli, N. J., López, M. A., Haeussler, C. A., Giordano, D. M., et al. (2019) · BMJ Paediatrics Open · doi:10.1136/bmjpo-2019-000473 · Cited by 102 · see citing works

Blood-based biomarkers for traumatic brain injury: Evaluation of research approaches, available methods and potential utility from the clinician and clinical laboratory perspectives

Strathmann, F. G., Schulte, S., Goerl, K., & Petron, D. J. (2014) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2014.01.028 · Cited by 98 · see citing works

The Biomarker S100B and Mild Traumatic Brain Injury: A Meta-analysis

Oris, C., Pereira, B., Durif, J., Simon-Pimmel, J., Castellani, C., Manzano, S., Sapin, V., & Bouvier, D. (2018) · PEDIATRICS · doi:10.1542/peds.2018-0037 · Cited by 97 · see citing works

Secondary Peaks of S100B in Serum Relate to Subsequent Radiological Pathology in Traumatic Brain Injury

Thelin, E. P., Nelson, D., & Bellander, B. (2013) · Neurocritical Care · doi:10.1007/s12028-013-9916-0 · Cited by 96 · see citing works

Modeling the Kinetics of Serum Glial Fibrillary Acidic Protein, Ubiquitin Carboxyl-Terminal Hydrolase-L1, and S100B Concentrations in Patients with Traumatic Brain Injury

Welch, R. D., Ellis, M. M., Lewis, L. M., Ayaz, S. I., Mika, V. H., Millis, S. R., & Papa, L. (2016) · Journal of Neurotrauma · doi:10.1089/neu.2016.4772 · Cited by 89 · see citing works

A Systematic Review of the Biomarker S100B: Implications for Sport-Related Concussion Management

Schulte, S., Podlog, L. W., Hamson-Utley, J. J., Strathmann, F. G., & Strüder, H. K. (2014) · Journal of Athletic Training · doi:10.4085/1062-6050-49.3.33 · Cited by 88 · see citing works

Age-Related Differences in Diagnostic Accuracy of Plasma Glial Fibrillary Acidic Protein and Tau for Identifying Acute Intracranial Trauma on Computed Tomography: A TRACK-TBI Study

Gardner, R. C., Rubenstein, R., Wang, K., Korley, F. K., Yue, J. K., Yuh, E. L., Mukherje, P., Valadka, A. B., Okonkwo, D. O., Diaz-Arrastia, R. R., et al. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5694 · Cited by 88 · see citing works

A Prospective Study of Acute Blood‐Based Biomarkers for Sport‐Related Concussion

Meier, T. B., Huber, D. L., Bohorquez‐Montoya, L., Nitta, M. E., Savitz, J. B., Teague, T. K., Bazarian, J. J., Hayes, R. L., Nelson, L. D., & McCrea, M. (2020) · Annals of Neurology · doi:10.1002/ana.25725 · Cited by 88 · see citing works

Role of S100B protein in urine and serum as an early predictor of mortality after severe traumatic brain injury in adults

Rodríguez-Rodríguez, A., Egea-Guerrero, J. J., León‐Justel, A., Gordillo-Escobar, E., Revuelto-Rey, J., Vilches‐Arenas, Á., Carrillo‐Vico, A., Domínguez-Roldán, J. M., Murillo-Cabezas, F., & Guerrero, J. M. (2012) · Clinica Chimica Acta · doi:10.1016/j.cca.2012.09.025 · Cited by 86 · see citing works

Comparing Glial Fibrillary Acidic Protein (GFAP) in Serum and Plasma Following Mild Traumatic Brain Injury in Older Adults

Huebschmann, N. A., Luoto, T. M., Karr, J. E., Berghem, K., Blennow, K., Zetterberg, H., Ashton, N. J., Simrén, J., Posti, J. P., Gill, J. M., et al. (2020) · Frontiers in Neurology · doi:10.3389/fneur.2020.01054 · Cited by 85 · see citing works

Kinetic modelling of serum S100b after traumatic brain injury

Ercole, A., Thelin, E. P., Holst, A., Bellander, B., & Nelson, D. (2016) · BMC Neurology · doi:10.1186/s12883-016-0614-3 · Cited by 84 · see citing works

Evaluation of Glial and Neuronal Blood Biomarkers Compared With Clinical Decision Rules in Assessing the Need for Computed Tomography in Patients With Mild Traumatic Brain Injury

Papa, L., Ladde, J. G., O’Brien, J. F., Thundiyil, J. G., Tesar, J. D., Leech, S. J., Cassidy, D. D., Roa, J. V., Hunter, C., Miller, S., et al. (2022) · JAMA Network Open · doi:10.1001/jamanetworkopen.2022.1302 · Cited by 83 · see citing works

Ubiquitin Carboxy-Terminal Hydrolase L1 (UCH-L1) is increased in cerebrospinal fluid and plasma of patients after epileptic seizure

Mondello, S., Palmio, J., Streeter, J., Hayes, R. L., Peltola, J., & Jeromin, A. (2012) · BMC Neurology · doi:10.1186/1471-2377-12-85 · Cited by 82 · see citing works

External validation of computed tomography decision rules for minor head injury: prospective, multicentre cohort study in the Netherlands

Foks, K. A., van den Brand, C. L., Lingsma, H. F., van der Naalt, J., Jacobs, B., de Jong, E., den Boogert, H. F., Sir, Ö., Patka, P., Polinder, S., et al. (2018) · BMJ · doi:10.1136/bmj.k3527 · Cited by 82 · see citing works

Developing a clinical decision instrument to rule out intracranial injuries in patients with minor head trauma: Methodology of the NEXUS II investigation

Mower, W. R., Hoffman, J. R., Herbert, M., Wolfson, A. B., Pollack, C. V., & Zucker, M. I. (2002) · Annals of Emergency Medicine · doi:10.1067/mem.2002.129245 · Cited by 81 · see citing works

Utility of Serum Biomarkers in the Diagnosis and Stratification of Mild Traumatic Brain Injury

Lewis, L. M., Schloemann, D. T., Papa, L., Fucetola, R. P., Bazarian, J. J., Lindburg, M. R., & Welch, R. D. (2017) · Academic Emergency Medicine · doi:10.1111/acem.13174 · Cited by 79 · see citing works

A Framework to Advance Biomarker Development in the Diagnosis, Outcome Prediction, and Treatment of Traumatic Brain Injury

Wilde, E. A., Wanner, I. B., Kenney, K., Gill, J., Stone, J. R., Disner, S. G., Caroline Schnakers, A., Meyer, R., Prager, E. M., Haas, M., et al. (2022) · Journal of Neurotrauma · doi:10.1089/neu.2021.0099 · Cited by 78 · see citing works

Ubiquitin C-terminal hydrolase-L1 (UCH-L1) as a therapeutic and diagnostic target in neurodegeneration, neurotrauma and neuro-injuries

Wang, K. K. W., Yang, Z.-H., Sarkis, G., Torres, I., & Raghavan, V. (2017) · Expert opinion on therapeutic targets · doi:10.1080/14728222.2017.1321635 · Cited by 75 · see citing works

Computed Tomography Use for Adults With Head Injury: Describing Likely Avoidable Emergency Department Imaging Based on the Canadian CT Head Rule

Sharp, A. L., Nagaraj, G., Rippberger, E. J., Shen, E., Swap, C. J., Silver, M. A., McCormick, T. N., Vinson, D. R., & Hoffman, J. R. (2017) · Academic Emergency Medicine · doi:10.1111/acem.13061 · Cited by 71 · see citing works

Serum biomarkers as predictors of long-term outcome in severe traumatic brain injury: analysis from a randomized placebo-controlled Phase II clinical trial

Raheja, A., Sinha, S., Samson, N., Bhoi, S. K., Subramanian, A., Sharma, P., & Sharma, B. S. (2016) · Journal of neurosurgery · doi:10.3171/2015.6.jns15674 · Cited by 69 · see citing works

Early Levels of Glial Fibrillary Acidic Protein and Neurofilament Light Protein in Predicting the Outcome of Mild Traumatic Brain Injury

Hossain, I., Mohammadian, M., Takala, R. S. K., Tenovuo, O. S., Lagerstedt, L., Ala-Seppälä, H. M., Frantzén, J., van Gils, M., Hutchinson, P. J., Katila, A. J., et al. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5952 · Cited by 69 · see citing works

The Known Unknowns: An Overview of the State of Blood-Based Protein Biomarkers of Mild Traumatic Brain Injury

McDonald, S. J., Shultz, S. R., & Agoston, D. V. (2021) · Journal of Neurotrauma · doi:10.1089/neu.2021.0011 · Cited by 68 · see citing works

Orthopedic Injured versus Uninjured Comparison Groups for Neuroimaging Research in Mild Traumatic Brain Injury

Wilde, E. A., Ware, A. L., Li, X., Wu, T. C., McCauley, S. R., Barnes, A., Newsome, M. R., Biekman, B. D., Hunter, J. V., Chu, Z. D., et al. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5513 · Cited by 68 · see citing works

S100B levels are affected by older age but not by alcohol intoxication following mild traumatic brain injury

Calcagnile, O., Holmén, A., Chew, M. S., & Undén, J. (2013) · Scandinavian Journal of Trauma Resuscitation and Emergency Medicine · doi:10.1186/1757-7241-21-52 · Cited by 65 · see citing works

Diagnostic Performance of GFAP, UCH-L1, and MAP-2 Within 30 and 60 Minutes of Traumatic Brain Injury

Papa, L., McKinley, W. I., Valadka, A. B., Newman, Z. C., Nordgren, R. K., Pramuka, P. E., Barbosa, C. E., Brito, A., Loss, L. J., Tinoco-Garcia, L., et al. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.31115 · Cited by 65 · see citing works

Testing a Multivariate Proteomic Panel for Traumatic Brain Injury Biomarker Discovery: A TRACK-TBI Pilot Study

Huie, J. R., Diaz-Arrastia, R. R., Yue, J. K., Sorani, M. D., Puccio, A. M., Okonkwo, D. O., Manley, G. T., Ferguson, A. R., the TRACK-TBI Investigators, Adeoye, O. M., et al. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5449 · Cited by 64 · see citing works

Comparison of GFAP and UCH-L1 Measurements from Two Prototype Assays: The Abbott i-STAT and ARCHITECT Assays

Korley, F. K., Datwyler, S. A., Jain, S., Sun, X., Beligere, G. S., Chandran, R., Marino, J. A., McQuiston, B., Zhang, H., Caudle, K. L., et al. (2021) · Neurotrauma Reports · doi:10.1089/neur.2020.0037 · Cited by 64 · see citing works

Serum neurofilament light chain reference database for individual application in paediatric care: a retrospective modelling and validation study

Abdelhak, A., Petermeier, F., Benkert, P., Schädelin, S., Oechtering, J., Maceski, A. M., Kabesch, M., Geis, T., Laub, O., Leipold, G., et al. (2023) · The Lancet Neurology · doi:10.1016/s1474-4422(23)00210-7 · Cited by 59 · see citing works

Increased Serum S100B Levels in Patients With Epilepsy: A Systematic Review and Meta-Analysis Study

Liang, K.-G., Mu, R.-Z., Liu, Y., Jiang, D., Jia, T., & Huang, Y. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00456 · Cited by 58 · see citing works

Neuroinflammatory Biomarkers for Traumatic Brain Injury Diagnosis and Prognosis: A TRACK-TBI Pilot Study

Yue, J. K., Kobeissy, F. H., Jain, S., Sun, X., Phelps, R. R. L., Korley, F. K., Gardner, R. C., Ferguson, A. R., Huie, J. R., Schneider, A. L. C., et al. (2023) · Neurotrauma Reports · doi:10.1089/neur.2022.0060 · Cited by 58 · see citing works

Age specific reference intervals for plasma biomarkers of neurodegeneration and neurotrauma in a Canadian population

Cooper, J. G., Stukas, S. K., Ghodsi, M., Ahmed, N., Diaz-Arrastia, R. R., Holmes, D. T., & Wellington, C. L. (2023) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2023.110680 · Cited by 58 · see citing works

Comparison of Four Different Assays for Determination of Serum S-100B

Smit, L., Korse, C. M., & Bonfrèr, J. M. G. (2005) · The International Journal of Biological Markers · doi:10.1177/172460080502000106 · Cited by 56 · see citing works

The Economic Impact of S-100B as a Pre-Head CT Screening Test on Emergency Department Management of Adult Patients with Mild Traumatic Brain Injury

Ruan, S., Noyes, K., & Bazarian, J. J. (2009) · Journal of Neurotrauma · doi:10.1089/neu.2009.0928 · Cited by 53 · see citing works

Classification Accuracy of Serum Apo A-I and S100B for the Diagnosis of Mild Traumatic Brain Injury and Prediction of Abnormal Initial Head Computed Tomography Scan

Bazarian, J. J., Blyth, B. J., He, H., Mookerjee, S., Jones, C. M. C., Kiechle, K., Moynihan, R., Wojcik, S. M., Grant, W. D., Secreti, L., et al. (2013) · Journal of Neurotrauma · doi:10.1089/neu.2013.2853 · Cited by 52 · see citing works

Utility of Acute and Subacute Blood Biomarkers to Assist Diagnosis in CT-Negative Isolated Mild Traumatic Brain Injury

Reyes, J., Spitz, G., Major, B. P., O’Brien, W. T., Giesler, L. P., Bain, J., Xie, B., Rosenfeld, J. V., Law, M., Ponsford, J. L., et al. (2023) · Neurology · doi:10.1212/wnl.0000000000207881 · Cited by 51 · see citing works

Biomarkers for Traumatic Brain Injury: Data Standards and Statistical Considerations

Huie, J. R., Mondello, S., Lindsell, C. J., Antiga, L., Yuh, E. L., Zanier, E. R., Masson, S., Rosario, B. L., Ferguson, A. R., Adeoye, O. M., et al. (2020) · Journal of Neurotrauma · doi:10.1089/neu.2019.6762 · Cited by 50 · see citing works

Management of patients suffering from mild traumatic brain injury 2023

Gil‐Jardine, C., Payen, J., Bernard, R., Bobbia, X., Bouzat, P., Catoire, P., Chauvin, A., Claessens, Y.-É., Douay, B., Dubucs, X., et al. (2023) · Anaesthesia Critical Care & Pain Medicine · doi:10.1016/j.accpm.2023.101260 · Cited by 50 · see citing works

Prospective Validation of the Scandinavian Guidelines for Initial Management of Minimal, Mild, and Moderate Head Injuries in Adults

Minkkinen, M., Iverson, G. L., Kotilainen, A., Pauniaho, S., Mattila, V. M., Lehtimäki, T. J., Berghem, K., Posti, J. P., & Luoto, T. M. (2019) · Journal of Neurotrauma · doi:10.1089/neu.2018.6351 · Cited by 50 · see citing works

Implementation of the Canadian CT Head Rule and Its Association With Use of Computed Tomography Among Patients With Head Injury

Sharp, A. L., Huang, B. Z., Tang, T., Shen, E., Melnick, E. R., Venkatesh, A. K., Kanter, M. H., & Gould, M. K. (2017) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2017.06.022 · Cited by 49 · see citing works

A Systematic Review of the Usefulness of Glial Fibrillary Acidic Protein for Predicting Acute Intracranial Lesions following Head Trauma

Luoto, T. M., Raj, R., Posti, J. P., Gardner, A. J., Panenka, W. J., & Iverson, G. L. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00652 · Cited by 49 · see citing works

The 2022 Lady Estelle Wolfson lectureship on neurofilaments

Petzold, A. (2022) · Journal of Neurochemistry · doi:10.1111/jnc.15682 · Cited by 49 · see citing works

Plasma glial fibrillary acidic protein and neurofilament light chain, but not tau, are biomarkers of sports-related mild traumatic brain injury

Laverse, E., Guo, T., Zimmerman, K. A., Foiani, M. S., Velani, B., Morrow, P., Adejuwon, A., Bamford, R., Underwood, N., George, J., et al. (2020) · Brain Communications · doi:10.1093/braincomms/fcaa137 · Cited by 49 · see citing works

Blood-based traumatic brain injury biomarkers – Clinical utilities and regulatory pathways in the United States, Europe and Canada

Wang, K., Pareja, J. C. M., Mondello, S., Diaz-Arrastia, R. R., Wellington, C. L., Kenney, K., Puccio, A. M., Hutchison, J. S., McKinnon, N. K., Okonkwo, D. O., et al. (2021) · Expert Review of Molecular Diagnostics · doi:10.1080/14737159.2021.2005583 · Cited by 47 · see citing works

Concussion BASICS III

Asken, B. M., Bauer, R. M., DeKosky, S. T., Svingos, A. M., Hromas, G. A., Boone, J. K., Dubose, D., Hayes, R. L., & Clugston, J. R. (2018) · Neurology · doi:10.1212/wnl.0000000000006617 · Cited by 45 · see citing works

One-Year Prospective Study of Plasma Biomarkers From CNS in Patients With Mild Traumatic Brain Injury

Clarke, G. J. B., Skandsen, T., Zetterberg, H., Einarsen, C. E., Feyling, C., Follestad, T., Vik, A., Blennow, K., & Håberg, A. K. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.643743 · Cited by 43 · see citing works

Governmental perspectives on evaluating laboratory performance

Boone, D. J. (1993) · Clinical Chemistry · doi:10.1093/clinchem/39.7.1461 · Cited by 41 · see citing works

Effects of age and time since injury on traumatic brain injury blood biomarkers: a TRACK-TBI study

Gardner, R. C., Puccio, A. M., Korley, F. K., Wang, K., Diaz-Arrastia, R. R., Okonkwo, D. O., Puffer, R. C., Yuh, E. L., Yue, J. K., Sun, X., et al. (2022) · Brain Communications · doi:10.1093/braincomms/fcac316 · Cited by 38 · see citing works

Serum β-synuclein, neurofilament light chain and glial fibrillary acidic protein as prognostic biomarkers in moderate-to-severe acute ischemic stroke

Barba, L., Vollmuth, C., Abu‐Rumeileh, S., Halbgebauer, S., Oeckl, P., Steinacker, P., Kollikowski, A. M., Schultz, C., Wolf, J., Pham, M., et al. (2023) · Scientific Reports · doi:10.1038/s41598-023-47765-7 · Cited by 37 · see citing works

Cost-Effectiveness of Biomarker Screening for Traumatic Brain Injury

Su, Y. S., Schuster, J. M., Smith, D. H., & Stein, S. C. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.6020 · Cited by 36 · see citing works

Assessment of Blood Biomarker Profile After Acute Concussion During Combative Training Among US Military Cadets

Giza, C. C., McCrea, M., Huber, D. L., Cameron, K. L., Houston, M. N., Jackson, J. C., McGinty, G. T., Pasquina, P. F., Broglio, S. P., Brooks, A., et al. (2021) · JAMA Network Open · doi:10.1001/jamanetworkopen.2020.37731 · Cited by 36 · see citing works

Reference ranges for neuroprotein S-100B: from infants to adolescents

Castellani, C., Stojaković, T., Cichocki, M., Scharnagl, H., Erwa, W., Gutmann, A., & Weinberg, A. (2008) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm.2008.262 · Cited by 33 · see citing works

Annals of Emergency Medicine

(2012) · Wilderness and Environmental Medicine · doi:10.1016/j.wem.2012.02.008 · Cited by 33 · see citing works

Sex differences in time course and diagnostic accuracy of GFAP and UCH-L1 in trauma patients with mild traumatic brain injury

Papa, L., Brophy, G. M., Alvarez, W., Hirschl, R., Cress, M. C., Weber, K. D., & Giordano, P. (2023) · Scientific Reports · doi:10.1038/s41598-023-38804-4 · Cited by 30 · see citing works

Discordance between Documented Criteria and Documented Diagnosis of Traumatic Brain Injury in the Emergency Department

Cota, M. R., Moses, A. D., Jikaria, N. R., Bittner, K. C., Diaz-Arrastia, R. R., Latour, L. L., & Turtzo, L. C. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2018.5772 · Cited by 29 · see citing works

ALERT-TBI study on biomarkers for TBI: has science suffered?

Maas, A. I. R., & Lingsma, H. F. (2018) · The Lancet Neurology · doi:10.1016/s1474-4422(18)30275-8 · Cited by 29 · see citing works

Serum assessment of traumatic axonal injury: the correlation of GFAP, t-Tau, UCH-L1, and NfL levels with diffusion tensor imaging metrics and its prognosis utility

Castaño-León, A. M., Carabias, C. S., Hilario, A., Ramos, A., Navarro-Main, B., Paredes, I., Munarriz, P. M., Panero, I., Fernández, C. E., García‐Pérez, D., et al. (2022) · Journal of neurosurgery · doi:10.3171/2022.5.jns22638 · Cited by 29 · see citing works

Variability in Discharge Instructions and Activity Restrictions for Patients in a Children’s ED Postconcussion

Maio, V. J. D., Joseph, D. O., Tibbo-Valeriote, H., Cabañas, J. G., Lanier, B., Mann, C. H., & Register‐Mihalik, J. K. (2013) · Pediatric Emergency Care · doi:10.1097/pec.0000000000000058 · Cited by 27 · see citing works

Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury

Button, E. B., Cheng, W. H., Barrón, C., Cheung, H., Bashir, A., Cooper, J. G., Gill, J., Stukas, S. K., Baron, D. C., Robert, J., et al. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00793-9 · Cited by 27 · see citing works

Evaluation of the analytical and clinical performance of a new high-sensitivity cardiac troponin I assay: hs-cTnI (CLIA) assay

Li, L., Shu, X., Zhang, L., Ao, X., Yang, J., Jing, Y., Wang, H., & Zhang, Z. (2023) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2023-0529 · Cited by 26 · see citing works

S100 serum level

Bottoni, U., Izzo, P., Richetta, A. G., Mannooranparampil, T. J., Devirgiliis, V., Giudice, M. D., Reale, M. G., Frati, L., & Calvieri, S. (2003) · Melanoma Research · doi:10.1097/00008390-200308000-00014 · Cited by 25 · see citing works

Outlier Analysis for Acute Blood Biomarkers of Moderate and Severe Traumatic Brain Injury

Korhonen, O., Mononen, M., Mohammadian, M., Tenovuo, O. S., Blennow, K., Hossain, I., Hutchinson, P. J., Maanpää, H.-R., Menon, D. K., Newcombe, V., et al. (2023) · Journal of Neurotrauma · doi:10.1089/neu.2023.0120 · Cited by 22 · see citing works

S100B Serum Level as a Mortality Predictor for Traumatic Brain Injury: A Meta-Analysis

Golden, N., Mahadewa, T. G. B., Aryanti, C., & Widyadharma, I. P. E. (2018) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2018.432 · Cited by 22 · see citing works

Basal IL‐6 and S100b levels are associated with infarct volume

Purroy, F. F., Farré‐Rodriguez, J., Mauri, G., Pascual, M. V., & Farré, J. (2021) · Acta Neurologica Scandinavica · doi:10.1111/ane.13487 · Cited by 20 · see citing works

Analysis of common biomarkers in capillary blood in routine clinical laboratory. Preanalytical and analytical comparison with venous blood

Maroto‐García, J., Deza, S., Fuentes-Bullejos, P., Fernández-Tomás, P., Martínez, D., Marcos‐Jubilar, M., Varo, N., & González, Á. (2023) · Diagnosis · doi:10.1515/dx-2022-0126 · Cited by 20 · see citing works

Plasma neurofilament light admission levels and development of axonal pathology in mild traumatic brain injury

Hossain, I., Mohammadian, M., Maanpää, H.-R., Takala, R. S. K., Tenovuo, O. S., van Gils, M., Hutchinson, P. J., Menon, D. K., Newcombe, V., Tallus, J., et al. (2023) · BMC Neurology · doi:10.1186/s12883-023-03284-6 · Cited by 19 · see citing works

Cost-Effectiveness of Blood-Based Brain Biomarkers for Screening Adults with Mild Traumatic Brain Injury in the French Health Care Setting

Zimmer, L., McDade, C. L., Beyhaghi, H., Purser, M. F., Textoris, J., Krause, A., Blanc, E., Pavlov, V., & Earnshaw, S. (2022) · Journal of Neurotrauma · doi:10.1089/neu.2022.0270 · Cited by 17 · see citing works

Association of Blood Biomarkers of Inflammation With Acute Concussion in Collegiate Athletes and Military Service Academy Cadets

Meier, T. B., Huber, D. L., Goeckner, B. D., Gill, J., Pasquina, P. F., Broglio, S. P., McAllister, T. W., Harezlak, J., & McCrea, M. (2023) · Neurology · doi:10.1212/wnl.0000000000207991 · Cited by 15 · see citing works

Associations of Microvascular Injury-Related Biomarkers With Traumatic Brain Injury Severity and Outcomes: A Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Pilot Study

Schneider, A. L. C., Huie, J. R., Jain, S., Sun, X., Ferguson, A. R., Lynch, C., Yue, J. K., Manley, G. T., Wang, K., Sandsmark, D. K., et al. (2023) · Journal of Neurotrauma · doi:10.1089/neu.2022.0442 · Cited by 13 · see citing works

Demographic and Clinical Characteristics Associated With Serum GFAP Levels in an Ethnically Diverse Cohort

Gonzales, M. M., Vela, G. D., Philip, V., Trevino, H., LaRoche, A., Wang, C., Parent, D. M., Kautz, T. F., Satizábal, C. L., Tanner, J. A., et al. (2023) · Neurology · doi:10.1212/wnl.0000000000207706 · Cited by 13 · see citing works

Food and Drug Administration (U.S.)

(2010) · Encyclopedia of Nanoscience and Society · doi:10.4135/9781412972093.n132 · Cited by 5 · see citing works

A Pilot Study Investigating the Use of Serum Glial Fibrillary Acidic Protein to Monitor Changes in Brain White Matter Integrity After Repetitive Head Hits During a Single Collegiate Football Game

Bazarian, J. J., Abar, B. W., Merchant‐Borna, K., Pham, D. L., Rozen, E., Mannix, R., Kawata, K., Chou, Y., Stephen, S. J., & Gill, J. (2024) · Journal of Neurotrauma · doi:10.1089/neu.2023.0307 · Cited by 4 · see citing works

Plasma von Willebrand Factor Is Elevated Hyperacutely After Mild Traumatic Brain Injury

Thomas, R. E., Lynch, C., Debad, J. D., Campbell, C. L., Chidomere, O., Kilianski, J., Ding, K., Madden, C. J., Sandsmark, D. K., Diaz-Arrastia, R. R., et al. (2023) · Neurotrauma Reports · doi:10.1089/neur.2023.0044 · Cited by 4 · see citing works

Clinical Assessment on Days 1–14 for the Characterization of Traumatic Brain Injury: Recommendations from the 2024 NINDS Traumatic Brain Injury Classification and Nomenclature Initiative Clinical/Symptoms Working Group

Menon, D. K., Silverberg, N. D., Ferguson, A. R., Bayuk, T. J., Bhattacharyay, S., Brody, D. L., Cota, S. A., Ercole, A., Figaji, A. A., Gao, G., et al. (2025) · Journal of Neurotrauma · doi:10.1089/neu.2024.0577 · Cited by 36 · see citing works

Toward More Holistic Early Traumatic Brain Injury Evaluation and Care: Recommendations from the 2024 National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Psychosocial and Environmental Modifiers Working Group

Nelson, L. D., Wilson, L., Albrecht, J. S., Arciniegas, D. B., Barthélemy, E. J., Fontaine, S. N., Gardner, R. C., Juengst, S. B., Pappadis, M. R., Ponsford, J. L., et al. (2025) · Journal of Neurotrauma · doi:10.1089/neu.2024.0569 · Cited by 25 · see citing works

Marking a New Age in Characterization of Acute Traumatic Brain Injury: The National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative

Manley, G. T., Dams-O’Connor, K., Awwad, H. O., Doperalski, A. E., Umoh, N., Maas, A. I. R., & McCrea, M. (2025) · Journal of Neurotrauma · doi:10.1089/neu.2025.0134 · Cited by 13 · see citing works

GFAP degradation in TBI: linking novel modified products to astrocyte pathology and patient outcome

Wanner, I. B., Halford, J., Lopez, J., Shen, S., Chen, Y., Zhao, H., Salas, C., Loo, R. R. O., Robicsek, S. A., Ellingson, B. M., et al. (2026) · Acta Neuropathologica Communications · doi:10.1186/s40478-026-02240-y · Cited by 5 · see citing works

WHITE MATTER MATTERS: New Approach to the Brain’s Hidden Half Using Circulating Oligodendrocyte-Derived Extracellular Vesicles

Mitsuhashi, M., Epps, D. V., Sun, H., Xing, L., Kawata, K., Jiménez, V., Williams, V. B., Sasannejad, C., James, M. L., Edwardson, M. A., et al. (2025) · Cells · doi:10.3390/cells14221771 · Cited by 4 · see citing works

Non-invasive intracranial pressure estimation in the intensive care unit: narrative review of methods and clinical applications

Picetti, E., Biasucci, D. G., Bogossian, E. G., Brasil, S., Cardim, D., Czosnyka, M., Godoy, D. A., Hawryluk, G. W. J., Hirzallah, M. I., Rasulo, F. A., et al. (2026) · Intensive Care Medicine · doi:10.1007/s00134-026-08420-7 · Cited by 4 · see citing works

The Boston Assessment of Traumatic Brain Injury Lifetime, Second Edition (BATL-2): Development and Initial Psychometric Evaluation in Post-9/11 Military Veterans

Colaizzi, T. A., Kenna, A. C., Knight, A. R., Clermont, C., Currao, A., & Fortier, C. B. (2025) · Journal of Head Trauma Rehabilitation · doi:10.1097/htr.0000000000001112 · Cited by 4 · see citing works

Mapping the secondary response to traumatic brain injury using spatial transcriptomics shows acute 4-aminopyridine treatment mitigates axonal and molecular pathology

Sullivan, G. M., Radomski, K. L., He, S., Wilkerson, M. D., Dalgard, C. L., Alba, C., Zi, X., Doughty, M. L., & Armstrong, R. C. (2026) · Acta Neuropathologica Communications · doi:10.1186/s40478-025-02219-1 · Cited by 3 · see citing works

Association of acute blood biomarkers with diffusion tensor imaging and outcome in patients with traumatic brain injury presenting with GCS of 13–15

Mononen, M., Mohammadian, M., Hossain, I., Roine, T., Tenovuo, O. S., Blennow, K., Gill, J., van Gils, M., Hutchinson, P. J., Luoto, T. M., et al. (2025) · NeuroImage Clinical · doi:10.1016/j.nicl.2025.103934 · Cited by 2 · see citing works

Uncovering the Role of Thrombospodin-1 and Occludin as Potential Prognostic and Diagnostic Biomarkers in Traumatic Brain Injury

Decouty‐Pérez, C., Valencia, I., Álvarez‐Rubal, M., Martínez-Cuevas, E., Farré‐Alins, V., Calzada, M. J., Peñalba, A., Montaner, J., de Cía, J. R., Taravilla-Loma, M., et al. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27020571 · Cited by 2 · see citing works

Development of a monoclonal antibody-based time-resolved fluorescence immunochromatographic assay strip for rapid and quantitative determination of S100B in serum

Feng, R., Wang, Y., Chen, Y., Li, T., Zhou, H., Zhan, Z., He, Y., Tang, X., Su, J., Guo, Y., et al. (2026) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-026-06430-4 · Cited by 2 · see citing works

Whole-blood point-of-care glial fibrillary acidic protein and ubiquitin C-terminal hydrolase L1 biomarkers after traumatic brain injury in the US: a prospective diagnostic prediction of intracranial injury on head CT

Puccio, A. M., McCrea, M., Okonkwo, D. O., Pradhan-Bhatt, S., Curley, K., Moss, A., Gupta, M., Wyse, E., Pahwa, D., HOFFMAN, D., et al. (2026) · The Lancet Regional Health - Americas · doi:10.1016/j.lana.2026.101539 · Cited by 2 · see citing works

Evaluating cognitive performance using the National Institutes of Health Toolbox Cognitive Battery in children with traumatic brain injury

Petersen, B., Vo, N.-T. N., Anton, N., Yeates, K. O., & Treble-Barna, A. (2025) · Journal of the International Neuropsychological Society · doi:10.1017/s135561772510146x · Cited by 1 · see citing works

What traditional neuropsychological assessment got wrong about mild traumatic brain injury. III: the added value of advanced neuroimaging

Bigler, E. D., Allder, S. J., Dunkley, B. T., & Victoroff, J. (2025) · Brain Injury · doi:10.1080/02699052.2025.2551164 · Cited by 1 · see citing works

Association of Marshall CT Scores with GFAP, UCH-L1, Tau, NfL, and p-Tau231 After Traumatic Brain Injury

Edwards, K. A., Alice, J., Day, M., Yun, J., Yun, S., Dark, H. E., Gabor, L., & Gill, J. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms262411765 · Cited by 1 · see citing works

The protective effect of neurointerventional recanalization on the neurovascular unit in acute ischemic stroke and its correlation with serum GFAP and NfL levels

Luo, J., Yang, Y., & Zhou, J. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2025.1721872 · Cited by 1 · see citing works

Integrated application of Raman spectroscopy in traumatic brain injury: A systematic review and clinical perspective

David, L., Borșa, R.-M., Onaciu, A., Voicescu, G.-T., Moldovan, C. S., Toma, V., Știufiuc, G.-F., Lupan-Mureșan, E.-M., Stiufiuc, R. I., & Golea, A. C. (2026) · Experimental Neurology · doi:10.1016/j.expneurol.2026.115677 · Cited by 1 · see citing works

Civilian Traumatic Brain Injury Is Associated with Longitudinally Increased Risk of PTSD, Suicidality, and Other Mental Health Diagnoses

Halabi, C., Mills, H., DiGiorgio, A. M., Schenk, G., Israni, S., Peek-Asa, C. L., & Manley, G. T. (2026) · Journal of Neurotrauma · doi:10.1177/08977151251414145 · Cited by 1 · see citing works

From scaffold to effector: reframing GFAP in neurodegeneration

Lu, Y.-H., Zhu, X., Li, S., Zhang, F., Cai, C.-B., Tian, M., Zhu, Y., Zeng, L.-H., Tan, J., Changyin, Y., et al. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2026.02.051 · Cited by 1 · see citing works

Neurofilament light chain but not glial fibrillary acidic protein serum levels are elevated in Wolfram syndrome

Jansen, M. J., Lugar, H. M., BROWN, C. M., Tang, A. F., Oiknine, L., Chen, L., Koller, J. M., Gordon, B. A., Marshall, B. A., Urano, F., et al. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1805916 · Cited by 1 · see citing works

Restoring mitochondrial health after blast-induced traumatic brain injury: modifiable factors and therapeutic opportunities

Laye, C. J., & Hubbard, W. B. (2026) · npj Metabolic Health and Disease · doi:10.1038/s44324-026-00111-7 · Cited by 1 · see citing works

Capillary UCH-L1 protein blood measurement is affected by sample hemolysis

Bouthors, B., Puravet, A., Chabanne, R., Durif, J., Bouvier, D., Sapin, V., & Braïlova, M. (2026) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2026-0471 · Cited by 1 · see citing works

Pathway-level proteomics identifies subcellular trafficking dysregulation as a molecular signature in severe traumatic brain injury

Nynatten, L. R. V., Tweddell, D., Daley, M., Cepinskas, G., Basmaji, J., Slessarev, M., & Fraser, D. D. (2026) · Inflammation Research · doi:10.1007/s00011-026-02287-6 · Cited by 1 · see citing works

From Brain to Blood: Point-of-Care Detection of Biomarkers in Neurological Diseases

Han, S., Feng, E. J., & Xiong, L. (2026) · ACS Sensors · doi:10.1021/acssensors.6c01472 · Cited by 1 · see citing works

Advances in biomarkers for diagnosing and prognosticating disorders of consciousness

Yang, X., Luo, Y., Zhiqun, C., Li, Y., Pan, L., Wang, P., & Chen, Z. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1823376 · Cited by 1 · see citing works

Letter: From Classification to Clinical Care: Reflections on Blood Biomarkers in TBI

Pernod, C., & Beucler, N. (2025) · Journal of Neurotrauma · doi:10.1177/08977151251384937

Advances in Understanding the Outcomes of Pediatric Traumatic Brain Injury: From Baby Steps to Bigger Leaps.

Suskauer, S., & Yeates, K. (2025) · The journal of head trauma rehabilitation · doi:10.1097/htr.0000000000001127

Development of a Structured Interview for the American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild Traumatic Brain Injury

Lange, R. T., Gillow, K. C., on behalf of ACRM Brain Injury Special Interest Group Mild TBI Task Force members:, Silverberg, N. D., Wallace, T. D., Panenka, W. J., Rabinowitz, A. R., Stephens, J. A., Dams-O’Connor, K., Delmonico, R. L., et al. (2025) · Journal of Neurotrauma · doi:10.1177/08977151251396077

Glial Fibrillary Acidic Protein: A Potential Therapeutic Target for Migraine

Liao, L., Luo, S., Zeng, Z., Luo, Y., & Mao, F. (2026) · World Journal of Clinical Medicine · doi:10.57237/j.wjcm.2026.01.001

Neuroworsening from a normal Glasgow Coma Scale Motor Score in the emergency department is an early predictor of neurosurgical intervention, hospital outcomes, and longitudinal disability in traumatic brain injury: A TRACK-TBI Study

Yue, J., Fu, A. Y., Elguindy, M. M., van Essen, T. A., Eagle, S. R., Caldwell, D. J., MS, R., Belton, P. J., Gotthardt, C. J., Bhattacharyay, S., et al. (2026) · Injury · doi:10.1016/j.injury.2026.113089

Blood Biomarkers for Identifying Epidural Hematoma in Patients Presenting with a Glasgow Coma Scale of 13–15: A Collaborative European Neurotrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study

Malmi, K., Pisică, D., Hossain, I., Mohammadian, M., van Essen, T. H., Luoto, T. M., Mondello, S., Takala, R. S. K., Tenovuo, O. S., Vyvere, T. V., et al. (2026) · Journal of Neurotrauma · doi:10.1177/08977151261430239

History of Neurotrauma Research at University of California, Davis

Lyeth, B. G., & Shahlaie, K. (2026) · Neurotrauma Reports · doi:10.1177/2689288x261428892

Vision transformers for neurological disorder diagnosis: a systematic review of architectural taxonomies, challenges, and future directions

Ameri, R., Shahmirzadi, D., Yarahmadi, A., & Nadimi-Shahraki, M. H. (2026) · Expert Systems with Applications · doi:10.1016/j.eswa.2026.132331

The emerging role of serum neurofilaments in pediatric neurological disorders

Svěráková, A., & Rostasy, K. M. (2026) · European Journal of Paediatric Neurology · doi:10.1016/j.ejpn.2026.05.003

The Long Road Back: An Integrative and Interdisciplinary Approach to Care After Traumatic Brain Injury

Zhang, Y., Majeres, K., Mendoza, A. D., & Chiang, H. (2026) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000457

Protein Predictors of Worsening Cerebral Edema in Traumatic Brain Injury in Critically Ill PatientsPreprint

Radabaugh, H. L., Abdelhak, A., Ning, K., Jha, R. M., Rowell, S., Pollock, J. M., Mendoza, E., Rojas-Valencia, L. M., Ferguson, A. R., & Hinson, H. E. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.23.727416

Acute Assessment of Sports-Related Concussion from the Sideline to the Emergency Department

Lehman, A. B., & Zieman, G. (2026) · Neurologic Clinics · doi:10.1016/j.ncl.2026.03.005

Neurofilament light and glial fibrillary acidic protein do not reflect neuronal or glial damage during different intracranial radiotherapy regimes: a pilot study

Dzierma, Y., Sebb, H., Utzig, M., Abdullayev, N., Berdel, C., Ruebe, C., Fleckenstein, J., Hecht, M., Hildebrandt, G., Jucker, M., et al. (2026) · Frontiers in Oncology · doi:10.3389/fonc.2026.1745704

Proteomic blood-based biomarkers of brain damage in traumatic brain injury: are they suitable surrogate endpoints for cerebral pressure autoregulatory-guided therapy?

Kevci, R., Hånell, A., Aries, M. J. H., Åkerlund, C. A. I., Büki, A., Bhattacharyay, S., Tommaso, G. D., Hendrix, R. H. J., Newcombe, V., Lewén, A., et al. (2026) · Critical Care · doi:10.1186/s13054-026-06132-4

Clinical laboratory strategies: Innovative biosensors for detecting traumatic brain injury biomarkers

Niaki, N. M., Alivirdiloo, V., Jafarzadeh, S., Jahani, S., Chaparzade, S., Koohkansaadi, G., Charsouei, S., & Mobed, A. (2026) · Sensing and Bio-Sensing Research · doi:10.1016/j.sbsr.2026.101037

Blood-based biomarkers GFAP/UCH-L1 for the diagnosis of mild traumatic brain injury (mTBI): a single-center implementation experience

Maegele, M., Breidenbach, L., Kaufmann, J., Keles, Y., Uhl, E., & Schroeer, P. (2026) · European Journal of Trauma and Emergency Surgery · doi:10.1007/s00068-026-03244-y

Blood-Based Mechanistic Biomarkers Improve Prognostication of Functional Outcome After Mild Traumatic Brain Injury

Visser, K., de Koning, M. E., Jacobs, B., Bourgonje, A. R., Chayouâ, W., van Faassen, M. H. J. R., van der Ley, C., Kema, I. P., van Goor, H., van der Naalt, J., et al. (2026) · Journal of Neurotrauma · doi:10.1177/08977151261468223

Serum Biomarkers for Early Prediction of Outcome After Moderate-to-Severe Traumatic Brain Injury

Rahim, R., Mushtaq, U., & Abbas, E. (2026) · Developmental medico-life-sciences · doi:10.69750/dmls.03.06.0216

Disease-modifying effects on chronic axon damage and white matter degeneration with 4-aminopyridine after acute traumatic brain injury

Radomski, K. L., Zi, X.-M., Sullivan, G. M., & Armstrong, R. C. (2026) · Neurotherapeutics · doi:10.1016/j.neurot.2026.e00975

Construction and Internal Validation of a Prediction Model for Awakening Outcomes after Hyperbaric Oxygen Therapy in Patients with Disorders of Consciousness following Severe Traumatic Brain Injury

赵, 雨. (2026) · Advances in Clinical Medicine · doi:10.12677/acm.2026.1672749

Biomarcadores séricos en el traumatismo craneoencefálico: utilidad clínica actual

Torres, J. Y., Yaguana, W. S. M., Valdiviezo, I. D. L., Navarrete, F. N. I., & Hidalgo, Y. A. R. (2026) · Salud Medicina e Innovación Journal · doi:10.70577/hcx64d58

A paradigm shift in traumatic brain injury: what does the CBI-M classification offer?

Büki, A., Rostami, E., Depreitere, B., & Marklund, N. (2026) · Brain and Spine · doi:10.1016/j.bas.2026.106259

Bio-cognitive Cut-Points Differentiate Risk vs. No Risk for Prodromal Parkinson Cognition in Young Post-mTBI Veterans and Non-mTBI ControlsPreprint

Nejtek, V. A., James, R., Boehm, G. W., Alphonso, H. M., Brice, K. N., Soto, I., Braden-Kuhle, P. N., Doshier, K., & Salvatore, M. F. (2026) · medRxiv · doi:10.64898/2026.08.10.26360106

Impact of routine use of the GFAP and UCH-L1 TBI blood test for management of mild TBI on patient care in a European emergency department

Brüning-Wolter, F., Wolff, N., Schrader, M., Musaelyan, K., Chandran, R., Hoffmann, M., Marino, J. A., McQuiston, B., & Cramer, J. (2026) · European Journal of Trauma and Emergency Surgery · doi:10.1007/s00068-026-03303-4

Effects of pneumatic tube transport on neurofilament light chain, neuron-specific enolase, and cardiac biomarkers

Huang, W.-C., Arabian, H., Cetaj, D., Waldmann, M., Erler-Zirnwald, R., Renné, T., & Eckelt, F. (2026) · Journal of Laboratory Medicine · doi:10.1515/labmed-2026-0112

Traumatic Brain Injury in Austere Environments: a Review of Recent Advances

Loaiza-Cardona, L. M., Casia, D. F. B., & Rubiano, A. M. (2026) · Current Neurology and Neuroscience Reports · doi:10.1007/s11910-026-01508-z

Translational benchmarking of 3D in vitro models of traumatic brain injury

Hsi, P. H., Lovett, M. L., Tandon, V., & Kaplan, D. L. (2026) · Trends in biotechnology · doi:10.1016/j.tibtech.2026.09.014

Inflammatory profiling for precision neurorehabilitation after traumatic brain injury and stroke: a narrative review

Calabrò, R. S., Calderone, A., Ardizzone, A., Ciancarelli, I., Morone, G., Cammaroto, S., Rifici, C., & Quartarone, A. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2026.1854973

Biomarqueurs sanguins du traumatisme crânien léger en 2026

Sapin, V. (2026) · Annales Pharmaceutiques Françaises · doi:10.1016/j.pharma.2026.09.005

Accuracy of the novel automated VIDAS TBI (GFAP, UCH-L1) assay for ruling out acute intracranial traumatic lesions in patients under 65 years of age with mild traumatic brain injury in an Emergency Department: An exploratory study

Fernández, E. P., Jorquera, E. M., Noblía, L., Reina, A. F., Alonso, J. V., Morales, F. M. G., Gil, J. M. S., Morales, M. G., & de Guadiana‐Romualdo, L. G. (2026) · Annals of Clinical Biochemistry International Journal of Laboratory Medicine · doi:10.1177/00045632261497264

SPLASH: a benchtop platform for accessible, ultrasensitive quantification of plasma biomarkers in Alzheimer’s disease

Elder, N., Nguyen, H., 완자손, Johnson, T. P., Lee, M., Ng, C., Yokoyama, J. S., & Lin, R. (2026) · Scientific Reports · doi:10.1038/s41598-026-74727-6

Early Detection of Metabolic-Dysfunction Associated Steatotic Liver Disease Using FIB-4

Low, Y. L. (2026) · Emerald Group Publishing Limited eBooks · doi:10.1108/978-1-83742-662-120261020

Readying Asia-Pacific health systems for integration of blood-based biomarkers in mild traumatic brain injury assessment: An expert opinion review

Yokobori, S., Lee, C.-C., Cordero, J., Musaad, S., Liao, K.-H., Braganza, L., & Ho, P. (2026) · Neurotrauma Reports · doi:10.1177/2689288x261494895

Current Concepts on Moderate Traumatic Brain Injury: Challenges and Future Perspectives

Splavski, B. (2026) · IntechOpen eBooks · doi:10.5772/intechopen.1016102

Diagnostics features of mild traumatic brain injury: modern approaches and prospects for improvement

Alekseyenko, Y. V. (2026) · Vestnik of Vitebsk State Medical University · doi:10.22263/2312-4156.2026.4.9

Clinical safety assessment of implanted brain-computer interfaces: current evidence and a pathway to standardization

Xing, B., Zhang, L., & Tu, W.-J. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1994636

Neuroimaging Characterization of Acute Traumatic Brain Injury with Focus on Frontline Clinicians: Recommendations from the 2024 National Institute of Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Imaging Working Group

MacDonald, C. L., Yuh, E. L., Vyvere, T. V., Edlow, B. L., Li, L. M., Mayer, A. R., Mukherjee, P., Newcombe, V., Wilde, E. A., Koerte, I. K., et al. (2025) · Journal of Neurotrauma · doi:10.1089/neu.2025.0079 · Cited by 33 · see citing works

Blood biomarkers for traumatic brain injury: A narrative review of current evidence

Hossain, I., Marklund, N., Czeiter, E., Hutchinson, P. J., & Büki, A. (2023) · Brain and Spine · doi:10.1016/j.bas.2023.102735 · Cited by 103 · see citing works

Updating Traumatic Brain Injury Classification for Surgeons: Integrating the CBI‐M Framework Into Trauma and Acute Care Practice

Peralta, R. R., Cardona-Collazos, S., Msheik, A., Gonzalez, W. D., Salazar, A. F., Loaiza-Cardona, L. M., & Rubiano, A. M. (2026) · World Journal of Surgery · doi:10.1002/wjs.70440 · Cited by 1 · see citing works

Blood‐based biomarkers and traumatic brain injury—A clinical perspective

Posti, J. P., & Tenovuo, O. S. (2022) · Acta Neurologica Scandinavica · doi:10.1111/ane.13620 · Cited by 27 · see citing works

Blood proteomic biomarkers in acute diagnostics of traumatic brain injury: Studies on adult patients with traumatic brain injury

Koivikko, P. (2026) · UTUPub (University of Turku)