Cited by 189Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration MechanismsNeural dynamics and brain function

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Do stars govern our actions? Astrocyte involvement in rodent behavior

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Oliveira, João Filipe, Sardinha, Vanessa Morais, Guerra-Gomes, Sónia, Araque, Alfonso, Sousa, Nuno·2015·Trends in Neurosciences

DOI 10.1016/j.tins.2015.07.006

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Abstract

Astrocytes have emerged as important partners of neurons in information processing. Important progress has been made in the past two decades in understanding the role of astrocytes in the generation of neuron-astrocyte network outputs resulting in behavior. We review evidence for astrocyte involvement across four different behavioral domains: cognition, emotion, motor, and sensory processing. Accumulating evidence from animal models has provided a wealth of data that largely supports a direct involvement of astrocytes on diverse aspects of behavior. The development of tools for selectively controlling the temporal and spatial properties of astrocyte activity will help to consolidate our knowledge of the mechanisms underlying this involvement.

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Authors: Oliveira, J. F., Sardinha, V. M., Guerra-Gomes, S., Araque, A., & Sousa, N.
Affiliations: University of Minho (PT)
University of Minnesota (US)
Corresponding author: Oliveira, João Filipe
ORCID: Oliveira, João Filipe
Araque, Alfonso
Sousa, Nuno
Venue: Trends in Neurosciences
Publisher: Elsevier BV
Published: 2015-09
Volume: 38
Issue: 9
Pages: 535-549
ISSN: 0166-2236 (ISSN-L)
DOI: 10.1016/j.tins.2015.07.006
OpenAlex: W1646393677
Cited by: 189
References: 120
Citations by year: 2026: 5 · 2025: 17 · 2024: 15 · 2023: 22 · 2022: 15 · 2021: 24 · 2020: 21 · 2019: 23 · 2018: 15 · 2017: 17 · 2016: 14 · 2015: 1
FWCI: 1.86
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Trends in Neurosciences (publishedVersion)
PubMed (publishedVersion)
RepositóriUM (Universidade do Minho) (submittedVersion, other-oa)
Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT) (submittedVersion, cc-by-nc-nd)
Funders: European Commission (273936)
National Science Council
Fundação Bial
Fundação para a Ciência e a Tecnologia (SFRH/BD/101298/2014, COMPETE, PTDC/SAU-NSC/118194/2010, SFRH/BPD/97281/2013)
FP7 People: Marie-Curie Actions
Topics: Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords: astrocytes, astrocyte-neuron interaction, behavior, cognition, emotions, motor behavior, sensory processing, rodent models
MeSH terms: Animals, Astrocytes, Behavior, Animal, Mental Processes, Neurons, Rodentia

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Do stars govern our actions? Astrocyte involvement in rodent behavior

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