Astrocyte–neuron metabolic relationships: for better and for worse

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

Hardy, J., & Selkoe, D. J. (2002) · Science · doi:10.1126/science.1072994 · Cited by 13,864 · see citing works

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0619-8 · Cited by 5,196 · see citing works

Mechanisms underlying inflammation in neurodegeneration

Glass, C. K., Saijo, K., Winner, B., Marchetto, M. C., & Gage, F. H. (2010) · Cell · doi:10.1016/j.cell.2010.02.016 · Cited by 3,580 · see citing works

A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function

Cahoy, J. D., Emery, B., Kaushal, A., Foo, L. C., Zamanian, J. L., Christopherson, K. S., Xing, Y., Lubischer, J. L., Krieg, P. A., Krupenko, S. A., et al. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4178-07.2008 · Cited by 3,129 · see citing works

Tripartite synapses: astrocytes process and control synaptic information

Perea, G., Navarrete, M., & Araque, A. (2009) · Trends in Neurosciences · doi:10.1016/j.tins.2009.05.001 · Cited by 1,820 · see citing works

Metabolism and functions of glutathione in brain

Dringen, R. (2000) · Progress in Neurobiology · doi:10.1016/s0301-0082(99)00060-x · Cited by 1,702 · see citing works

Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia

Boillée, S., Yamanaka, K., Lobsiger, C. S., Copeland, N. G., Jenkins, N. A., Kassiotis, G., Kollias, G., & Cleveland, D. W. (2006) · Science · doi:10.1126/science.1123511 · Cited by 1,623 · see citing works

Uniquely Hominid Features of Adult Human Astrocytes

Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.4707-08.2009 · Cited by 1,488 · see citing works

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

Foust, K. D., Nurre, E., Montgomery, C. L., Hernandez, A., Chan, C. M., & Kaspar, B. K. (2009) · Nature Biotechnology · doi:10.1038/nbt.1515 · Cited by 1,456 · see citing works

ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors

Boillée, S., Velde, C. V., & Cleveland, D. W. (2006) · Neuron · doi:10.1016/j.neuron.2006.09.018 · Cited by 1,426 · see citing works

The Mystery and Magic of Glia: A Perspective on Their Roles in Health and Disease

Barres, B. A. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.013 · Cited by 1,352 · see citing works

Astrocytes are active players in cerebral innate immunity

Farina, C., Aloisi, F., & Meinl, E. (2007) · Trends in Immunology · doi:10.1016/j.it.2007.01.005 · Cited by 1,304 · see citing works

Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons

Nagai, M., Re, D. B., Nagata, T., Chalazonitis, A., Jessell, T. M., Wichterle, H., & Przedborski, S. (2007) · Nature Neuroscience · doi:10.1038/nn1876 · Cited by 1,220 · see citing works

Deciphering the Molecular Basis of Memory Failure in Alzheimer's Disease

Walsh, D. M., & Selkoe, D. J. (2004) · Neuron · doi:10.1016/j.neuron.2004.09.010 · Cited by 1,207 · see citing works

Glial regulation of the cerebral microvasculature

Iadecola, C., & Nedergaard, M. (2007) · Nature Neuroscience · doi:10.1038/nn2003 · Cited by 1,153 · see citing works

Astrocytes as determinants of disease progression in inherited amyotrophic lateral sclerosis

Yamanaka, K., Chun, S. J., Boillee, S., Fujimori-Tonou, N., Yamashita, H., Gutmann, D. H., Takahashi, R., Misawa, H., & Cleveland, D. W. (2008) · Nature Neuroscience · doi:10.1038/nn2047 · Cited by 1,140 · see citing works

Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice

Bush, T. G., Puvanachandra, N., Horner, C. H., Polito, A., Ostenfeld, T., Svendsen, C. N., Mucke, L., Johnson, M. H., & Sofroniew, M. V. (1999) · Neuron · doi:10.1016/s0896-6273(00)80781-3 · Cited by 1,116 · see citing works

Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

Ilieva, H., Polymenidou, M., & Cleveland, D. W. (2009) · Journal of Cell Biology · doi:10.1083/jcb.200908164 · Cited by 1,008 · see citing works

Metabolic coupling between glia and neurons

Tsacopoulos, M., & Magistretti, P. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-03-00877.1996 · Cited by 1,006 · see citing works

Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury

Okada, S., Nakamura, M., Katoh, H., Miyao, T., Shimazaki, T., Ishii, K., Yamane, J., Yoshimura, A., Iwamoto, Y., Toyama, Y., et al. (2006) · Nature Medicine · doi:10.1038/nm1425 · Cited by 971 · see citing works

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

Herrmann, J. E., Imura, T., Song, B., Qi, J., Ao, Y., Nguyen, T. K., Korsak, R. A., Takeda, K., Akira, S., & Sofroniew, M. V. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1709-08.2008 · Cited by 958 · see citing works

Adult mouse astrocytes degrade amyloid-β in vitro and in situ

Wyss-Coray, T., Loike, J. D., Brionne, T. C., Lu, E., Anankov, R., Yan, F., Silverstein, S. C., & Husemann, J. (2003) · Nature Medicine · doi:10.1038/nm838 · Cited by 909 · see citing works

Astrocytic Modulation of Sleep Homeostasis and Cognitive Consequences of Sleep Loss

Halassa, M. M., Florian, C., Fellin, T., Munoz, J. R., Lee, S.-Y., Abel, T. G., Haydon, P. G., & Frank, M. G. (2009) · Neuron · doi:10.1016/j.neuron.2008.11.024 · Cited by 877 · see citing works

Astrocytes Control Breathing Through pH-Dependent Release of ATP

Gourine, A. V., Kasymov, V., Marina, N., Tang, F., Figueiredo, M. F., Lane, S., Teschemacher, A. G., Spyer, K. M., Deisseroth, K. A., & Kasparov, S. (2010) · Science · doi:10.1126/science.1190721 · Cited by 871 · see citing works

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

Rouach, N., Koulakoff, A., Abudara, V., Willecke, K., & Giaume, C. (2008) · Science · doi:10.1126/science.1164022 · Cited by 861 · see citing works

Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

Gabathuler, R. (2009) · Neurobiology of Disease · doi:10.1016/j.nbd.2009.07.028 · Cited by 804 · see citing works

Non–cell autonomous effect of glia on motor neurons in an embryonic stem cell–based ALS model

Di Giorgio, F. P., Carrasco, M. A., Siao, M. C., Maniatis, T., & Eggan, K. (2007) · Nature Neuroscience · doi:10.1038/nn1885 · Cited by 799 · see citing works

Astrocyte dysfunction in neurological disorders: a molecular perspective

Seifert, G., Schilling, K., & Steinhäuser, C. (2006) · Nature reviews. Neuroscience · doi:10.1038/nrn1870 · Cited by 798 · see citing works

Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo

Nimmerjahn, A., Kirchhoff, F., Kerr, J. N. D., & Helmchen, F. (2004) · Nature Methods · doi:10.1038/nmeth706 · Cited by 784 · see citing works

Reactive Astrocytes in Neural Repair and Protection

Sofroniew, M. V. (2005) · The Neuroscientist · doi:10.1177/1073858405278321 · Cited by 742 · see citing works

Neuron-glia metabolic coupling and plasticity

Magistretti, P. J. (2006) · Experimental Physiology · doi:10.1113/expphysiol.2010.053157 · Cited by 739 · see citing works

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

Kuchibhotla, K. V., Lattarulo, C. R., Hyman, B. T., & Bacskai, B. J. (2009) · Science · doi:10.1126/science.1169096 · Cited by 729 · see citing works

Current hypotheses for the underlying biology of amyotrophic lateral sclerosis

Rothstein, J. D. (2009) · Annals of Neurology · doi:10.1002/ana.21543 · Cited by 691 · see citing works

Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease

Brenner, M., Johnson, T., Boespflug‐Tanguy, O., Rodriguez, D., Goldman, J. E., & Messing, A. (2001) · Nature Genetics · doi:10.1038/83679 · Cited by 689 · see citing works

Redefining the concept of reactive astrocytes as cells that remain within their unique domains upon reaction to injury

Wilhelmsson, U., Bushong, E. A., Price, D. L., Smarr, B. L., Phung, V., Terada, M., Ellisman, M. H., & Pekny, M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0602841103 · Cited by 643 · see citing works

Neurobiology of ammonia

Felipo, V., & Butterworth, R. F. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00019-9 · Cited by 626 · see citing works

Essential protective roles of reactive astrocytes in traumatic brain injury

Myer, D. J. (2006) · Brain · doi:10.1093/brain/awl165 · Cited by 617 · see citing works

Gliogenesis and Glial Pathology in Depression

Rajkowska, G., & Miguel-Hidalgo, J. J. (2007) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/187152707780619326 · Cited by 612 · see citing works

Epilepsy, Ataxia, Sensorineural Deafness, Tubulopathy, and KCNJ10 Mutations

Böckenhauer, D., Feather, S. A., Stanescu, H. C., et al. (2009) · New England Journal of Medicine · doi:10.1056/nejmoa0810276 · Cited by 594 · see citing works

Inhibition of astroglial nuclear factor κB reduces inflammation and improves functional recovery after spinal cord injury

Brambilla, R., Bracchi-Ricard, V. C., Hu, W.-H., Frydel, B. R., Bramwell, A., Karmally, S., Green, E. J., & Bethea, J. R. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20041918 · Cited by 589 · see citing works

β-Amyloid Peptides Induce Mitochondrial Dysfunction and Oxidative Stress in Astrocytes and Death of Neurons through Activation of NADPH Oxidase

Abramov, A. Y., Canevari, L., & Duchen, M. R. (2004) · The Journal of Neuroscience · doi:10.1523/jneurosci.4042-03.2004 · Cited by 587 · see citing works

Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson’s disease: Critical role for the astrocyte

Chen, P.-C., Vargas, M. R., Pani, A. K., Smeyne, R. J., Johnson, D. A., Kan, Y. W., & Johnson, J. A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813361106 · Cited by 579 · see citing works

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides

Koistinaho, M., Lin, S., Wu, X., Esterman, M., Koger, D., Hanson, J., Higgs, R., Liu, F., Malkani, S., Bales, K. R., et al. (2004) · Nature Medicine · doi:10.1038/nm1058 · Cited by 571 · see citing works

Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10

Scholl, U. I., Choi, M., Liu, T., Ramaekers, V. T., Häusler, M., Grimmer, J., Tobe, S. W., Farhi, A., Nelson-Williams, C. J., & Lifton, R. P. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0901749106 · Cited by 500 · see citing works

Concomitant astroglial atrophy and astrogliosis in a triple transgenic animal model of Alzheimer's disease

Olabarria, M., Noristani, H. N., Verkhratsky, A., & Rodríguez, J. J. (2010) · Glia · doi:10.1002/glia.20967 · Cited by 499 · see citing works

Contribution of glial cells to the development of amyloid plaques in Alzheimer’s disease

Nagele, R. G., Węgiel, J., Venkataraman, V., Imaki, H., Wang, K.-C., & Wegiel, J. (2004) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2004.01.007 · Cited by 497 · see citing works

The Transcriptome and Metabolic Gene Signature of Protoplasmic Astrocytes in the Adult Murine Cortex

Lovatt, D., Sonnewald, U., Waagepetersen, H. S., Schousboe, A., He, W., Lin, J. H.-C., Han, X., Takano, T., Wang, S., Sim, F. J., et al. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.3404-07.2007 · Cited by 488 · see citing works

Human Embryonic Stem Cell-Derived Motor Neurons Are Sensitive to the Toxic Effect of Glial Cells Carrying an ALS-Causing Mutation

Giorgio, F. P. D., Boulting, G. L., Bobrowicz, S., & Eggan, K. C. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.09.017 · Cited by 488 · see citing works

Neuron-Specific Expression of Mutant Superoxide Dismutase 1 in Transgenic Mice Does Not Lead to Motor Impairment

Pramatarova, A., Laganière, J., Roussel, J., Brisebois, K., & Rouleau, G. A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-10-03369.2001 · Cited by 482 · see citing works

Nrf2 Activation in Astrocytes Protects against Neurodegeneration in Mouse Models of Familial Amyotrophic Lateral Sclerosis

Vargas, M. R., Johnson, D. A., Sirkis, D. W., Messing, A., & Johnson, J. A. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.4099-08.2008 · Cited by 479 · see citing works

Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity

Shin, J., Fang, Z.-H., Yu, Z.-X., Wang, C.-E., Li, S., & Li, X. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200508072 · Cited by 475 · see citing works

Pro‐regenerative properties of cytokine‐activated astrocytes

Liberto, C. M., Albrecht, P. J., Herx, L. M., Yong, V. W., & Levison, S. W. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02420.x · Cited by 464 · see citing works

Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells

Marchetto, M. C., Muotri, A. R., Mu, Y., Smith, A. M., Cezar, G. G., & Gage, F. H. (2008) · Cell stem cell · doi:10.1016/j.stem.2008.10.001 · Cited by 455 · see citing works

Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease

Lepore, A. C., Rauck, B., Dejea, C., Pardo, A. C., Rao, M. S., Rothstein, J. D., & Maragakis, N. J. (2008) · Nature Neuroscience · doi:10.1038/nn.2210 · Cited by 441 · see citing works

Glial cells as intrinsic components of non-cell-autonomous neurodegenerative disease

Lobsiger, C. S., & Cleveland, D. W. (2007) · Nature Neuroscience · doi:10.1038/nn1988 · Cited by 438 · see citing works

Antioxidant defense of the brain: a role for astrocytes

Wilson, J. X. (1997) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y97-146 · Cited by 430 · see citing works

Astrocytes accumulate Aβ42 and give rise to astrocytic amyloid plaques in Alzheimer disease brains

Nagele, R. G., D’Andrea, M. R., Lee, H., Venkataraman, V., & Wang, H.-Y. (2003) · Brain Research · doi:10.1016/s0006-8993(03)02361-8 · Cited by 416 · see citing works

Cooperative Astrocyte and Dendritic Spine Dynamics at Hippocampal Excitatory Synapses

Haber, M., Zhou, L., & Murai, K. K. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.1302-06.2006 · Cited by 413 · see citing works

Heterogeneity in astrocyte morphology and physiology

Matyash, V., & Kettenmann, H. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.12.001 · Cited by 413 · see citing works

The role of astroglia in neuroprotection

Bélanger, M., & Magistretti, P. J. (2009) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2009.11.3/mbelanger · Cited by 396 · see citing works

Astroglia in dementia and Alzheimer's disease

Rodriguez, J. J., Olabarria, M., Chvátal, A., & Verkhratsky, A. (2008) · Cell Death and Differentiation · doi:10.1038/cdd.2008.172 · Cited by 396 · see citing works

Pathogenetic mechanisms of hepatic encephalopathy

Häussinger, D., & Schliess, F. (2008) · Gut · doi:10.1136/gut.2007.122176 · Cited by 391 · see citing works

Astrocyte phenotype in relation to Alzheimer‐type pathology in the ageing brain

Simpson, J. E., Ince, P. G., Lace, G., Forster, G., Shaw, P. J., Matthews, F., Savva, G., Brayne, C., & Wharton, S. B. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2008.05.015 · Cited by 381 · see citing works

Alzheimer Disease: Mechanistic Understanding Predicts Novel Therapies

Selkoe, D. J. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-140-8-200404200-00047 · Cited by 381 · see citing works

Restricted Expression of G86R Cu/Zn Superoxide Dismutase in Astrocytes Results in Astrocytosis But Does Not Cause Motoneuron Degeneration

Gong, Y. H., Parsadanian, A. S., Andreeva, A., Snider, W. D., & Elliott, J. L. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00660.2000 · Cited by 372 · see citing works

Regulation of Neuronal Glutathione Synthesis

Aoyama, K., Watabe, M., & Nakaki, T. (2008) · Journal of Pharmacological Sciences · doi:10.1254/jphs.08r01cr · Cited by 356 · see citing works

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

Faideau, M., Kim, J., Cormier, K., Gilmore, R., Welch, M. J., Aurégan, G., Dufour, N., Guillermier, M., Brouillet, E., Hantraye, P., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq212 · Cited by 343 · see citing works

Astrocytic expression of Parkinson's disease-related A53T α-synuclein causes neurodegeneration in mice

Gu, X., Long, C.-X., Sun, L., Xie, C., Lin, X. Z., & Cai, H. (2010) · Molecular Brain · doi:10.1186/1756-6606-3-12 · Cited by 341 · see citing works

Changes in Intracellular Calcium and Glutathione in Astrocytes as the Primary Mechanism of Amyloid Neurotoxicity

Abramov, A. Y., Canevari, L., & Duchen, M. R. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-12-05088.2003 · Cited by 337 · see citing works

Inflammation in central nervous system injury.

Allan, S., & Rothwell, N. (2003) · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · doi:10.1098/rstb.2003.1358 · Cited by 336 · see citing works

Astrocyte control of the cerebrovasculature

Gordon, G. R., Mulligan, S. J., & MacVicar, B. A. (2007) · Glia · doi:10.1002/glia.20543 · Cited by 323 · see citing works

Cystine/Glutamate Exchange Modulates Glutathione Supply for Neuroprotection from Oxidative Stress and Cell Proliferation

Shih, A. Y., Erb, H., Sun, X., Toda, S., Kalivas, P. W., & Murphy, T. H. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3178-06.2006 · Cited by 315 · see citing works

Astrocytes in multiple sclerosis: A product of their environment

Nair, A., Frederick, T., & Miller, S. D. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-008-8059-5 · Cited by 312 · see citing works

Plasticity of Astrocytic Coverage and Glutamate Transporter Expression in Adult Mouse Cortex

Genoud, C., Quairiaux, C., Steiner, P., Hirling, H., Welker, E., & Knott, G. W. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040343 · Cited by 304 · see citing works

Cytokines: Powerful Regulators of Glial Cell Activation

John, G. R., Lee, S. C., & Brosnan, C. F. (2003) · The Neuroscientist · doi:10.1177/1073858402239587 · Cited by 299 · see citing works

The Nrf2–ARE cytoprotective pathway in astrocytes

Vargas, M. R., & Johnson, J. A. (2009) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399409001094 · Cited by 289 · see citing works

Astrocyte dysfunction in epilepsy

Seifert, G., Carmignoto, G., & Steinhäuser, C. (2009) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.10.004 · Cited by 287 · see citing works

Transgenic Inhibition of Astroglial NF-κB Improves Functional Outcome in Experimental Autoimmune Encephalomyelitis by Suppressing Chronic Central Nervous System Inflammation

Brambilla, R., Persaud, T., Hu, X.-C., Karmally, S., Shestopalov, V., Dvoriantchikova, G., Ivanov, D., Nathanson, L., Barnum, S., & Bethea, J. (2009) · Journal of Immunology · doi:10.4049/jimmunol.0802954 · Cited by 285 · see citing works

Neuroprotective Role of Lactate after Cerebral Ischemia

Berthet, C., Lei, H., Thévenet, J., Rolf Gruetter, A., Magistretti, P. J., & Hirt, L. (2009) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2009.97 · Cited by 282 · see citing works

Amyloid-β Aggregates Cause Alterations of Astrocytic Metabolic Phenotype: Impact on Neuronal Viability

Allaman, I., Gavillet, M., Bélanger, M., Laroche, T., Viertl, D., Lashuel, H. A., & Magistretti, P. J. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.5098-09.2010 · Cited by 277 · see citing works

Glial fibrillary acidic protein mutations in infantile, juvenile, and adult forms of Alexander disease

Li, R., Johnson, T., Salomons, G. S., et al. (2005) · Annals of Neurology · doi:10.1002/ana.20406 · Cited by 274 · see citing works

Thrombospondins 1 and 2 are Necessary for Synaptic Plasticity and Functional Recovery after Stroke

Liauw, J. A., Hoang, S., Choi, M. Y., Eroğlu, Ç., Choi, M., Sun, G.-H., Percy, M., Wildman‐Tobriner, B., Bliss, T. M., Guzman, R. G., et al. (2008) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2008.65 · Cited by 263 · see citing works

Protection from mitochondrial complex II inhibition <i>in vitro</i> and <i>in vivo</i> by Nrf2-mediated transcription

Calkins, M. J., Jakel, R. J., Johnson, D. A., Chan, K., Kan, Y. W., & Johnson, J. A. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0408487101 · Cited by 247 · see citing works

Glial Glycogen Stores Affect Neuronal Survival during Glucose Deprivation in vitro

Swanson, R. A., & Choi, D. W. (1993) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1993.19 · Cited by 231 · see citing works

Astrocytes and Therapeutics for Parkinson's Disease

Rappold, P. M., & Tieu, K. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.07.001 · Cited by 228 · see citing works

Cholesterol homeostasis in neurons and glial cells

Vance, J. E., Hayashi, H., & Karten, B. (2005) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2005.01.005 · Cited by 222 · see citing works

A Glia-Derived Signal Regulating Neuronal Differentiation

Blondel, O., Collin, C., McCarran, W. J., Zhu, S. C., Zamostiano, R., Gozes, I., Brenneman, D., & Mckay, R. D. G. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-21-08012.2000 · Cited by 218 · see citing works

Gap Junction-Mediated Astrocytic Networks in the Mouse Barrel Cortex

Houades, V., Koulakoff, A., Ezan, P., Seif, I., & Giaume, C. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5100-07.2008 · Cited by 216 · see citing works

GFAP and its role in Alexander disease

Quinlan, R. A., Brenner, M., Goldman, J. E., & Messing, A. (2007) · Experimental Cell Research · doi:10.1016/j.yexcr.2007.04.004 · Cited by 207 · see citing works

Astrocytes produce the antiinflammatory and neuroprotective agent hydrogen sulfide

Lee, M., Schwab, C., Yu, S. Y., McGeer, E. G., & McGeer, P. L. (2009) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2009.06.001 · Cited by 206 · see citing works

Glial cells in schizophrenia: pathophysiological significance and possible consequences for therapy

Bernstein, H., Steiner, J. H., & Bogerts, B. (2009) · Expert Review of Neurotherapeutics · doi:10.1586/ern.09.59 · Cited by 189 · see citing works

Elevated connexin43 immunoreactivity at sites of amyloid plaques in alzheimer's disease

Nagy, J. I., Li, W., Hertzberg, E. L., & Marotta, C. A. (1996) · Brain Research · doi:10.1016/0006-8993(95)01526-4 · Cited by 180 · see citing works

Astrocyte Glycogen Sustains Neuronal Activity during Hypoglycemia: Studies with the Glycogen Phosphorylase Inhibitor CP-316,819 ([R-R*,S*]-5-Chloro-N-[2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1 H-indole-2-carboxamide)

Suh, S. W., Bergher, J. P., Anderson, C. M., Treadway, J. L., Fosgerau, K., & Swanson, R. A. (2007) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.115550 · Cited by 178 · see citing works

Astrocytic involvement in learning and memory consolidation

Gibbs, M. E., Hutchinson, D. S., & Hertz, L. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.02.001 · Cited by 174 · see citing works

Transgenic mice for conditional gene manipulation in astroglial cells

Ślęzak, M., Göritz, C., Niemiec, A., Frisén, J., Chambon, P., METZGER, D., & Pfrieger, F. W. (2007) · Glia · doi:10.1002/glia.20570 · Cited by 171 · see citing works

Opposing Roles for Reactive Astrocytes following Traumatic Brain Injury

Laird, M. D., Vender, J. R., & Dhandapani, K. M. (2008) · Neurosignals · doi:10.1159/000111560 · Cited by 171 · see citing works

Mutant Huntingtin in Glial Cells Exacerbates Neurological Symptoms of Huntington Disease Mice

Bradford, J. W., Shin, J., Redd, M. A., Wang, C.-E., Sheng, G., Li, S., & Li, X. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.083287 · Cited by 164 · see citing works

Transplanted astrocytes internalize deposited β‐amyloid peptides in a transgenic mouse model of Alzheimer's disease

Pihlaja, R., Koıstınaho, J., Malm, T., Sikkilä, H., Vainio, S. J., & Koistinaho, M. (2007) · Glia · doi:10.1002/glia.20599 · Cited by 162 · see citing works

Engineered lentiviral vector targeting astrocytes <i>In vivo</i>

Colin, A., Faideau, M., Dufour, N., Auregan, G., Hassig, R., Andrieu, T., Brouillet, E., Hantraye, P., Bonvento, G., & Déglon, N. (2009) · Glia · doi:10.1002/glia.20795 · Cited by 158 · see citing works

Fluorocitrate and fluoroacetate effects on astrocyte metabolism in vitro

Swanson, R. A., & Graham, S. H. (1994) · Brain Research · doi:10.1016/0006-8993(94)91958-5 · Cited by 154 · see citing works

Neuron-Astrocyte Signaling in the Development and Plasticity of Neural Circuits

Stevens, B. (2008) · Neurosignals · doi:10.1159/000123038 · Cited by 151 · see citing works

A metabolic switch in brain: glucose and lactate metabolism modulation by ascorbic acid

Castro, M. A., Beltrán, F. A., Brauchi, S. E., & Concha, I. I. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06151.x · Cited by 147 · see citing works

Inactivation of astroglial NF‐κB promotes survival of retinal neurons following ischemic injury

Dvoriantchikova, G., Barakat, D. J., Brambilla, R., Agudelo, C., Hernandez, E., Bethea, J. R., Shestopalov, V. I., & Ivanov, D. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2009.06814.x · Cited by 146 · see citing works

Astrocyte gp130 Expression Is Critical for the Control of Toxoplasma Encephalitis

Drögemüller, K., Helmuth, U., Brunn, A., Sakowicz‐Burkiewicz, M., Gutmann, D. H., Müller, W., Deckert, M., & Schlüter, D. (2008) · The Journal of Immunology · doi:10.4049/jimmunol.181.4.2683 · Cited by 140 · see citing works

Astrocytes and Epilepsy

de Lanerolle, N. C., Lee, T.-S. W., & Spencer, D. D. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2010.08.002 · Cited by 139 · see citing works

Glia as a Therapeutic Target: Selective Suppression of Human Amyloid-β-Induced Upregulation of Brain Proinflammatory Cytokine Production Attenuates Neurodegeneration

Ranaivo, H. R., Craft, J. M., Hu, W., Guo, L., Wing, L. K., Eldik, L. J. V., & Watterson, D. M. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4652-05.2006 · Cited by 137 · see citing works

Transgenic inhibition of astroglial NF‐κB leads to increased axonal sparing and sprouting following spinal cord injury

Brambilla, R., Hurtado, A., Persaud, T., Esham, K., Pearse, D. D., Oudega, M., & Bethea, J. R. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06190.x · Cited by 130 · see citing works

Role of glial cells in the formation and maintenance of synapses

Pfrieger, F. W. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2009.11.002 · Cited by 124 · see citing works

Astroglial connexin immunoreactivity is specifically altered at β-amyloid plaques in β-amyloid precursor protein/presenilin1 mice

Mei, X., Ezan, P., Giaume, C., & Koulakoff, A. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.08.001 · Cited by 119 · see citing works

BDNF regulation under GFAP promoter provides engineered astrocytes as a new approach for long-term protection in Huntington's disease

Giralt, A., Friedman, H. C., Caneda-Ferrón, B., Urbán, N., Moreno, E., Rubio, N., Blanco, J., Peterson, A. C., Canals, J. M., & Alberch, J. (2010) · Gene Therapy · doi:10.1038/gt.2010.71 · Cited by 106 · see citing works

Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis

Boucherie, C., Schäfer, S., Lavand'homme, P. M., Maloteaux, J., & Hermans, E. (2009) · Journal of Neuroscience Research · doi:10.1002/jnr.22038 · Cited by 100 · see citing works

Selective up-regulation of the glial Na+-dependent glutamate transporter GLT1 by a neuroimmunophilin ligand results in neuroprotection

Ganel, R., Ho, T. W., Maragakis, N. J., Jackson, M. T., Steiner, J. P., & Rothstein, J. D. (2005) · Neurobiology of Disease · doi:10.1016/j.nbd.2005.08.014 · Cited by 98 · see citing works

From Vasoactive Intestinal Peptide (VIP) Through Activity-Dependent Neuroprotective Protein (ADNP) to NAP: A View of Neuroprotection and Cell Division

Gozes, I., Divinski, I., Pilzer, I., Fridkin, M., Brenneman, D. E., & Spier, A. D. (2003) · Journal of Molecular Neuroscience · doi:10.1385/jmn:20:3:315 · Cited by 96 · see citing works

Live imaging of amyotrophic lateral sclerosis pathogenesis: Disease onset is characterized by marked induction of GFAP in Schwann cells

Keller, A. F., Gravel, M., & Križ, J. (2008) · Glia · doi:10.1002/glia.20836 · Cited by 96 · see citing works

Induction of Adult Human Bone Marrow Mesenchymal Stromal Cells into Functional Astrocyte-Like Cells: Potential for Restorative Treatment in Parkinson’s Disease

Bahat-Stromza, M., Barhum, Y., Levy, Y. S., Karpov, O., Bulvik, S., Melamed, E., & Offen, D. (2009) · Journal of Molecular Neuroscience · doi:10.1007/s12031-008-9166-3 · Cited by 93 · see citing works

Alexander disease: putative mechanisms of an astrocytic encephalopathy

Mignot, C., Boespflug‐Tanguy, O., Gélot, A., Dautigny, A., Pham-Dinh, D., & Rodriguez, D. (2004) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-003-3143-3 · Cited by 90 · see citing works

Two-photon Imaging of Glutathione Levels in Intact Brain Indicates Enhanced Redox Buffering in Developing Neurons and Cells at the Cerebrospinal Fluid and Blood-Brain Interface

Sun, X., Shih, A. Y., Johannssen, H. C., Erb, H., Li, P., & Murphy, T. H. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601567200 · Cited by 89 · see citing works

Altered glial–neuronal crosstalk: Cornerstone in the pathogenesis of hepatic encephalopathy

Butterworth, R. F. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.03.012 · Cited by 74 · see citing works

The Role of Excitatory Amino Acid Transporters in Cerebral Ischemia

Chao, X., Fei, F., & Fei, Z. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0178-3 · Cited by 71 · see citing works

Neuronal glial interaction in different neurological diseases studied by ex vivo13C NMR spectroscopy

Sonnewald, U., & Kondziella, D. (2003) · NMR in Biomedicine · doi:10.1002/nbm.837 · Cited by 68 · see citing works

Astrocyte modulation of in vitro β‐amyloid neurotoxicity

Paradisi, S., Sacchetti, B., Balduzzi, M., Gaudi, S., & Malchiodi‐Albedi, F. (2004) · Glia · doi:10.1002/glia.20005 · Cited by 68 · see citing works

Arundic Acid Ameliorates Cerebral Amyloidosis and Gliosis in Alzheimer Transgenic Mice

Mori, T., Town, T., Tan, J., Yada, N., Horikoshi, Y., Yamamoto, J., Shimoda, T., Kamanaka, Y., Tateishi, N., & Asano, T. (2006) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1124/jpet.106.105171 · Cited by 67 · see citing works

Viral-based modelling and correction of neurodegenerative diseases by RNA interference

Raoul, C., Barker, S. D., & Aebischer, P. (2005) · Gene Therapy · doi:10.1038/sj.gt.3302690 · Cited by 65 · see citing works

Dual-Gene, Dual-Cell Type Therapy against an Excitotoxic Insult by Bolstering Neuroenergetics

Bliss, T. M., Ip, M., Cheng, E., Minami, M., Pellerin, L., Magistretti, P. J., & Sapolsky, R. M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.0805-04.2004 · Cited by 63 · see citing works

Selective overexpression of excitatory amino acid transporter 2 (EAAT2) in astrocytes enhances neuroprotection from moderate but not severe hypoxia–ischemia

Weller, M. L., Stone, I. M., Goss, A., Rau, T., Rova, C. R. L., & Poulsen, D. J. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.05.059 · Cited by 62 · see citing works

Imaging of cortical astrocytes using 2-photon laser scanning microscopy in the intact mouse brain

Tian, G.-F., Takano, T., Lin, J. H.-C., Wang, X., Bekar, L. K., & Nedergaard, M. (2006) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2006.07.001 · Cited by 58 · see citing works

Transgenic mice expressing a cameleon fluorescent Ca2+ indicator in astrocytes and Schwann cells allow study of glial cell Ca2+ signals in situ and in vivo

Atkin, S. D., Patel, S., Kocharyan, A., Holtzclaw, L. A., Weerth, S. H., Schram, V., Pickel, J. M., & Russell, J. T. (2009) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2009.05.006 · Cited by 55 · see citing works

PET of Glial Metabolism Using 2-18F-Fluoroacetate

Mařı́k, J., Ogasawara, A. K., Martin-McNulty, B., Ross, J., Flores, J. E., Gill, H. S., Tinianow, J. N., Vanderbilt, A. N., Nishimura, M. C., Peale, F. V., Jr., et al. (2009) · Journal of Nuclear Medicine · doi:10.2967/jnumed.108.057356 · Cited by 44 · see citing works

A transgenic mouse model for the detailed morphological study of astrocytes

Suzuki, R., Watanabe, J., Arata, S., Funahashi, H., Kikuyama, S., & Shioda, S. (2003) · Neuroscience Research · doi:10.1016/j.neures.2003.08.008 · Cited by 43 · see citing works

Neuroprotective effect of arundic acid, an astrocyte-modulating agent, in mouse brain against MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) neurotoxicity

Himeda, T., Kadoguchi, N., Kamiyama, Y., Kato, H., Maegawa, H., & Araki, T. (2005) · Neuropharmacology · doi:10.1016/j.neuropharm.2005.09.014 · Cited by 20 · see citing works

In vivo targeting of subventricular zone astrocytes

Mamber, C., Verhaagen, J., & Hol, E. M. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.04.007 · Cited by 18 · see citing works

Hydrogen Sulfide as a Biological Mediator

Kimura, H. (2005) · Antioxidants and Redox Signaling · doi:10.1089/ars.2005.7.778 · Cited by 18 · see citing works

Brain energy metabolism: focus on Astrocyte-neuron metabolic cooperation

Bélanger, M., Allaman, I., & Magistretti, P. J. (2011) · Cell Metabolism · doi:10.1016/j.cmet.2011.08.016 · Cited by 2,313 · see citing works

13 reasons why the brain is susceptible to oxidative stress

Cobley, J. N., Fiorello, M. L., & Bailey, D. M. (2018) · Redox Biology · doi:10.1016/j.redox.2018.01.008 · Cited by 1,215 · see citing works

Metabolic Interactions in the Tumor Microenvironment

Lyssiotis, C. A., & Kimmelman, A. C. (2017) · Trends in Cell Biology · doi:10.1016/j.tcb.2017.06.003 · Cited by 853 · see citing works

Astrocytes and disease: a neurodevelopmental perspective

Molofsky, A. V., Krenick, R., Ullian, E., Tsai, H.-H., Deneen, B., Richardson, W. D., Barres, B. A., & Rowitch, D. H. (2012) · Genes &amp; Development · doi:10.1101/gad.188326.112 · Cited by 682 · see citing works

Functional diversity of astrocytes in neural circuit regulation

Haim, L. B., & Rowitch, D. H. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.159 · Cited by 618 · see citing works

Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease

Chinta, S. J., Woods, G., Demaria, M., Rane, A., Zou, Y., McQuade, A., Rajagopalan, S., Limbad, C., Madden, D. T., Campisi, J., et al. (2018) · Cell Reports · doi:10.1016/j.celrep.2017.12.092 · Cited by 530 · see citing works

Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons

Yang, J., Ruchti, E., Petit, J.-M., Jourdain, P., Grenningloh, G., Allaman, I., & Magistretti, P. J. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1322912111 · Cited by 504 · see citing works

Tau and neuroinflammation in Alzheimer’s disease: interplay mechanisms and clinical translation

Chen, Y., & Yu, Y. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02853-3 · Cited by 516 · see citing works

Astrocytes in Neurodegenerative Disease: Table 1.

Phatnani, H., & Maniatis, T. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a020628 · Cited by 420 · see citing works

Reactive astrocytes in neurodegenerative diseases

Li, K., Li, J., Zheng, J., & Qin, S. (2019) · Aging and disease · doi:10.14336/ad.2018.0720 · Cited by 398 · see citing works

Extracellular matrix and matrix receptors in blood–brain barrier formation and stroke

Baeten, K. M., & Akassoglou, K. (2011) · Developmental Neurobiology · doi:10.1002/dneu.20954 · Cited by 397 · see citing works

Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration

Sankowski, R., Mader, S., & Valdés-Ferrer, S. I. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00028 · Cited by 351 · see citing works

Glial glycolysis is essential for neuronal survival in Drosophila

Volkenhoff, A., Weiler, A., Letzel, M., Stehling, M., Klämbt, C., & Schirmeier, S. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2015.07.006 · Cited by 339 · see citing works

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

Kim, J. G., Suyama, S., Koch, M., Jin, S., Argente-Arizon, P., Argente, J., Liu, Z.-W., Zimmer, M. R., Jeong, J. K., Szigeti-Buck, K., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3725 · Cited by 336 · see citing works

Astroglial CB1 Receptors Determine Synaptic D-Serine Availability to Enable Recognition Memory

Robin, L. M., Oliveira da Cruz, J. F., Langlais, V. C., Martin-Fernandez, M., Metna-Laurent, M., Busquets-Garcia, A., Bellocchio, L., Soria-Gomez, E., Papouin, T., Varilh, M., et al. (2018) · Neuron · doi:10.1016/j.neuron.2018.04.034 · Cited by 262 · see citing works

Bioenergetics and redox adaptations of astrocytes to neuronal activity

Bolaños, J. P. (2016) · Journal of Neurochemistry · doi:10.1111/jnc.13486 · Cited by 262 · see citing works

Emerging role for astroglial networks in information processing: from synapse to behavior

Pannasch, U., & Rouach, N. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2013.04.004 · Cited by 251 · see citing works

Pathogenic LRRK2 mutations, through increased kinase activity, produce enlarged lysosomes with reduced degradative capacity and increase ATP13A2 expression

Henry, A. G., Aghamohammadzadeh, S., Samaroo, H., Chen, Y., Mou, K., Needle, E., & Hirst, W. D. (2015) · Human Molecular Genetics · doi:10.1093/hmg/ddv314 · Cited by 235 · see citing works

Review: Astrocytes in Alzheimer's disease and other age‐associated dementias: a supporting player with a central role

Garwood, C. J., Ratcliffe, L. E., Simpson, J. E., Heath, P. R., Ince, P. G., & Wharton, S. B. (2017) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12338 · Cited by 233 · see citing works

Hypothalamic control of energy balance: insights into the role of synaptic plasticity

Dietrich, M. O., & Horvath, T. L. (2013) · Trends in Neurosciences · doi:10.1016/j.tins.2012.12.005 · Cited by 227 · see citing works

The Drosophila blood-brain barrier: development and function of a glial endothelium

Limmer, S., Weiler, A., Volkenhoff, A., Babatz, F., & Klämbt, C. (2014) · Frontiers in Neuroscience · doi:10.3389/fnins.2014.00365 · Cited by 214 · see citing works

Human Stem Cell-Derived Spinal Cord Astrocytes with Defined Mature or Reactive Phenotypes

Roybon, L., Lamas, N. J., Garcia-Diaz, A., Yang, E. J., Sattler, R., Jackson-Lewis, V., Kim, Y. A., Kachel, C. A., Rothstein, J. D., Przedborski, S., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.06.021 · Cited by 208 · see citing works

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

Jimenez-Blasco, D., Santofimia-Castaño, P., Gonzalez, A., Almeida, A., & Bolaños, J. P. (2015) · Cell Death &amp; Differentiation · doi:10.1038/cdd.2015.49 · Cited by 196 · see citing works

Do stars govern our actions? Astrocyte involvement in rodent behavior

Oliveira, J. F., Sardinha, V. M., Guerra-Gomes, S., Araque, A., & Sousa, N. (2015) · Trends in Neurosciences · doi:10.1016/j.tins.2015.07.006 · Cited by 189 · see citing works

Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

Adesso, S., Magnus, T., Cuzzocrea, S., Campolo, M., Rissiek, B., Paciello, O., Autore, G., Pinto, A., & Marzocco, S. (2017) · Frontiers in Pharmacology · doi:10.3389/fphar.2017.00370 · Cited by 184 · see citing works

Co-stimulation with IL-1β and TNF-α induces an inflammatory reactive astrocyte phenotype with neurosupportive characteristics in a human pluripotent stem cell model system

Hyvärinen, T., Hagman, S., Ristola, M., Sukki, L., Veijula, K., Kreutzer, J., Kallio, P., & Narkilahti, S. (2019) · Scientific Reports · doi:10.1038/s41598-019-53414-9 · Cited by 168 · see citing works

Astrocytic cytoskeletal atrophy in the medial prefrontal cortex of a triple transgenic mouse model of Alzheimer's disease

Kulijewicz‐Nawrot, M., Verkhratsky, A., Chvátal, A., Syková, E., & Rodríguez, J. J. (2012) · Journal of Anatomy · doi:10.1111/j.1469-7580.2012.01536.x · Cited by 160 · see citing works

Disrupting astrocyte–neuron lactate transfer persistently reduces conditioned responses to cocaine

Boury-Jamot, B., Carrard, A., Martin, J. L., Halfon, O., Magistretti, P. J., & Boutrel, B. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.157 · Cited by 116 · see citing works

Chronic psychosocial stress and citalopram modulate the expression of the glial proteins GFAP and NDRG2 in the hippocampus

Araya-Callís, C., Hiemke, C., Abumaria, N., & Flugge, G. (2012) · Psychopharmacology · doi:10.1007/s00213-012-2741-x · Cited by 109 · see citing works

Inhibition of Lactate Transport Erases Drug Memory and Prevents Drug Relapse

Zhang, Y., Xue, Y., Meng, S., Luo, Y., Liang, J., Li, J., Ai, S., Sun, C., Shen, H., Zhu, W., et al. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.07.007 · Cited by 106 · see citing works

Aberrant astrocytes impair vascular reactivity in <scp>H</scp>untington disease

Hsiao, H., Chen, Y., Huang, C., Chen, C., Hsu, Y., Chen, H., Chiu, F., Kuo, H., Chang, C., & Chern, Y. (2015) · Annals of Neurology · doi:10.1002/ana.24428 · Cited by 99 · see citing works

Regulation of neuron-astrocyte metabolic coupling across the sleep-wake cycle

Petit, J.-M., & Magistretti, P. J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.007 · Cited by 92 · see citing works

Revisiting enigmatic cortical calretinin-expressing interneurons

Cauli, B., Zhou, X., Tricoire, L., Toussay, X., & Staiger, J. F. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00052 · Cited by 86 · see citing works

Deficiency of macrophage migration inhibitory factor attenuates tau hyperphosphorylation in mouse models of Alzheimer’s disease

Li, S.-Q., Yu, Y., Han, J.-Z., Wang, D., Liu, J., Qian, F., Fan, G.-H., Bucala, R., & Ye, R. D. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0396-3 · Cited by 59 · see citing works

Elevated CLOCK and BMAL1 contribute to the impairment of aerobic glycolysis from astrocytes in Alzheimer's disease

Yoo, I. D., Park, M. W., Cha, H. W., Yoon, S., Boonpraman, N., Yi, S. S., & Moon, J.-S. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21217862 · Cited by 51 · see citing works

Downregulated expression of lactate dehydrogenase in adult oligodendrocytes and its implication for the transfer of glycolysis products to axons

Späte, E., Zhou, B., Sun, T., Kusch, K., Asadollahi, E., Siems, S. B., Depp, C., Werner, H. B., Saher, G., Hirrlinger, J., et al. (2024) · Glia · doi:10.1002/glia.24533 · Cited by 40 · see citing works

Senescence in aging and disorders of the central nervous system

Swenson, B. L., Meyer, C. F., Bussian, T. J., & Baker, D. J. (2019) · Translational Medicine of Aging · doi:10.1016/j.tma.2019.01.002 · Cited by 24 · see citing works

Genetics of Amyotrophic Lateral Sclerosis

Gorodenker, J., & Levy, L. M. (2014) · American Journal of Neuroradiology · doi:10.3174/ajnr.a3831 · Cited by 4 · see citing works

Phosphorylated TDP-43 aggregates in peripheral motor nerves of patients with amyotrophic lateral sclerosis

Riva, N., Gentile, F., Cerri, F., Gallia, F., Podini, P., Dina, G., Falzone, Y., Fazio, R., Lunetta, C., Calvo, A., et al. (2021) · Brain · doi:10.1093/brain/awab285 · Cited by 59 · see citing works

Amyotrophic Lateral Sclerosis Sera Applied to Cultured Motor Neurons

Horwich, M., Engel, W. K., & Chauvin, P. B. (1974) · Archives of Neurology · doi:10.1001/archneur.1974.00490340060015 · Cited by 39 · see citing works

"Lipopolysaccharide-induced animal models for neuroinflammation – An overview."

Silva, A., Fiadeiro, M. B., Bernardino, L. I., Fonseca, C. P., Baltazar, G., & Cristóvão, A. C. (2023) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2023.578273 · Cited by 76 · see citing works

Diagnosis and Treatment of Amyotrophic Lateral Sclerosis

Yang, F. (2011) · Zhongguo quanke yixue