Reversal of West Nile virus-induced blood–brain barrier disruption and tight junction proteins degradation by matrix metalloproteinases inhibitor

Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis

Wang, T., Town, T., Alexopoulou, L., Anderson, J. F., Fikrig, E., & Flavell, R. A. (2004) · Nature Medicine · doi:10.1038/nm1140 · Cited by 1,155 · see citing works

Blood–brain Barrier: Structural Components and Function Under Physiologic and Pathologic Conditions

Persidsky, Y., Ramirez, S. H., Haorah, J., & Kanmogne, G. D. (2006) · Journal of Neuroimmune Pharmacology · doi:10.1007/s11481-006-9025-3 · Cited by 922 · see citing works

Matrix metalloproteinases in neuroinflammation

Rosenberg, G. A. (2002) · Glia · doi:10.1002/glia.10108 · Cited by 868 · see citing works

Matrix metalloproteinase inhibitors as therapy for inflammatory and vascular diseases

Hu, J., den Steen, P. E. V., Sang, Q. A., & Opdenakker, G. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2308 · Cited by 798 · see citing works

Multiple roles for MMPs and TIMPs in cerebral ischemia

Cunningham, L. A., Wetzel, M. K., & Rosenberg, G. A. (2005) · Glia · doi:10.1002/glia.20169 · Cited by 410 · see citing works

West Nile Virus: Epidemiology and Clinical Features of an Emerging Epidemic in the United States

Hayes, E. B., & Gubler, D. J. (2005) · Annual Review of Medicine · doi:10.1146/annurev.med.57.121304.131418 · Cited by 366 · see citing works

Junctional complexes of the blood–brain barrier: permeability changes in neuroinflammation

Petty, M. A., & Lo, E. H. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00128-4 · Cited by 361 · see citing works

Vasogenic edema due to tight junction disruption by matrix metalloproteinases in cerebral ischemia

Rosenberg, G. A., & Yang, Y. R. (2007) · Neurosurgical FOCUS · doi:10.3171/foc.2007.22.5.5 · Cited by 358 · see citing works

A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis

Persidsky, Y., Stins, M. F., Way, D., Witte, M., Weinand, M. E., Kim, K. S., Bock, P., Gendelman, H. E., & Fiala, M. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.7.3499 · Cited by 316 · see citing works

Matrix Metalloproteinase-3: A Novel Signaling Proteinase from Apoptotic Neuronal Cells That Activates Microglia

Kim, Y.-S., Kim, S. S., Cho, J., Choi, D.-H., Hwang, O., Shin, D., Hong, S.-C., Beal, M., & Joh, T. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.4346-04.2005 · Cited by 272 · see citing works

Differential matrix metalloproteinase expression in cases of multiple sclerosis and stroke

Anthony, D. C., Ferguson, B., Matyzak, M. K., Miller, K., Esiri, M. M., & Perry, V. H. (1997) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1997.tb01315.x · Cited by 268 · see citing works

Matrix metalloproteinases: multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis

Leppert, D., Lindberg, R. L. P., Kappos, L., & Leib, S. L. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00101-1 · Cited by 255 · see citing works

West Nile virus infection modulates human brain microvascular endothelial cells tight junction proteins and cell adhesion molecules: Transmigration across the in vitro blood-brain barrier

Verma, S., Lo, Y. Y., Chapagain, M. L., Lum, S., Kumar, M., Gurjav, U., Luo, H., Nakatsuka, A. S., & Nerurkar, V. R. (2009) · Virology · doi:10.1016/j.virol.2008.11.047 · Cited by 255 · see citing works

Matrix metalloproteinases and processing of pro-TNF-α

Gearing, A. J. H., Beckett, P., Christodoulou, M., Churchill, M., Clements, J. M., Crimmin, M., Davidson, A. H., Drummond, A. H., Gallowav, W. A., Gilbert, R. J. C., et al. (1995) · Journal of Leukocyte Biology · doi:10.1002/jlb.57.5.774 · Cited by 232 · see citing works

HIV-1 gp120 Compromises Blood–Brain Barrier Integrity and Enhance Monocyte Migration across Blood–Brain Barrier: Implication for Viral Neuropathogenesis

Kanmogne, G. D., Schall, K. A., Leibhart, J., Knipe, B., Gendelman, H. E., & Persidsky, Y. (2006) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600330 · Cited by 230 · see citing works

Gelatinase B modulates selective opening of the blood-brain barrier during inflammation

Mun-Bryce, S., & Rosenberg, G. A. (1998) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1998.274.5.r1203 · Cited by 230 · see citing works

Matrix Metalloproteinases in Brain Injury

Rosenberg, G. A. (1995) · Journal of Neurotrauma · doi:10.1089/neu.1995.12.833 · Cited by 225 · see citing works

Cytokine and chemokine regulation of proMMP-9 and TIMP-1 production by human peripheral blood lymphocytes

JOHNATTY, R. N., Taub, D. D., Reeder, S., Turcovski‐Corrales, S. M., Cottam, D. W., Stephenson, T. J., & Rees, R. C. (1997) · The Journal of Immunology · doi:10.4049/jimmunol.158.5.2327 · Cited by 205 · see citing works

Innate and Adaptive Immune Responses Determine Protection against Disseminated Infection by West Nile Encephalitis Virus

Diamond, M., Shrestha, B., Mehlhop, E., Sitati, E. M., & Engle, M. J. (2003) · Viral Immunology · doi:10.1089/088282403322396082 · Cited by 197 · see citing works

Matrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain

Wang, P., Dai, J., Bai, F., Kong, K., Wong, S. J., Montgomery, R. R., Madri, J. A., & Fikrig, E. (2008) · Journal of Virology · doi:10.1128/jvi.00314-08 · Cited by 186 · see citing works

Clinical implications of matrix metalloproteinases

Mandal, M., Mandal, A., Das, S. K., Chakraborti, T., & Chakraborti, S. (2003) · Molecular and Cellular Biochemistry · doi:10.1023/a:1025526424637 · Cited by 171 · see citing works

Matrix metalloproteinase-9 is associated with blood-brain barrier opening and brain edema formation after cortical contusion in rats

Shigemori, Y., Katayama, Y., Mori, T., Maeda, T., & Kawamata, T. (2006) · Springer eBooks · doi:10.1007/3-211-30714-1_29 · Cited by 158 · see citing works

Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion

Arjona, A., Foellmer, H. G., Town, T., Leng, L., McDonald, C., Wang, T., Wong, S. J., Montgomery, R. R., Fikrig, E., & Bucala, R. (2007) · Journal of Clinical Investigation · doi:10.1172/jci32218 · Cited by 158 · see citing works

Elevation of matrix metalloproteinases (MMPs) in multiple sclerosis and impact of immunomodulators

Yong, V. W., Zabad, R., Agrawal, S., DaSilva, A. G., & Metz, L. M. (2007) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2006.11.021 · Cited by 156 · see citing works

STAT1 signaling modulates HIV-1–induced inflammatory responses and leukocyte transmigration across the blood-brain barrier

Chaudhuri, A., Yang, B. Y., Gendelman, H. E., Persidsky, Y., & Kanmogne, G. D. (2007) · Blood · doi:10.1182/blood-2007-05-091207 · Cited by 145 · see citing works

Differential responses of human brain cells to West Nile virus infection

Cheeran, M. C. ‐., Hu, S., Sheng, W. S., Rashid, A., Peterson, P. K., & Lokensgard, J. R. (2005) · Journal of NeuroVirology · doi:10.1080/13550280500384982 · Cited by 143 · see citing works

Stromelysin‐1 (MMP‐3) is critical for intracranial bleeding after t‐PA treatment of stroke in mice

SUZUKI, Y., NAGAI, N., Umemura, K., Collen, D., & LIJNEN, H. R. (2007) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2007.02628.x · Cited by 142 · see citing works

Methamphetamine alters blood brain barrier permeability via the modulation of tight junction expression: Implication for HIV-1 neuropathogenesis in the context of drug abuse

Mahajan, S. D., Aalinkeel, R., Sykes, D. E., Reynolds, J. L., Bindukumar, B., Adal, A., Qi, M., Toh, J., Xu, G., Prasad, P. N., et al. (2008) · Brain Research · doi:10.1016/j.brainres.2008.01.093 · Cited by 139 · see citing works

West Nile Virus-Induced Neuroinflammation: Glial Infection and Capsid Protein-Mediated Neurovirulence

van Marle, G., Antony, J. M., Ostermann, H., Dunham, C. P., Hunt, T. A., HALLIDAY, W. C., Maingat, F. G., Urbanowski, M. D., Hobman, T. C., Peeling, J., et al. (2007) · Journal of Virology · doi:10.1128/jvi.02422-06 · Cited by 128 · see citing works

Dendritic Cell Transmigration through Brain Microvessel Endothelium Is Regulated by MIP-1α Chemokine and Matrix Metalloproteinases

Zozulya, A. L., Reinke, E. K., Baiu, D. C., Kármán, J., Sándor, M., & Fábry, Z. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.1.520 · Cited by 115 · see citing works

Kaposi's Sarcoma-Associated Herpesvirus Infection Promotes Invasion of Primary Human Umbilical Vein Endothelial Cells by Inducing Matrix Metalloproteinases

Qian, L., Xie, J., Ye, F., & Gao, S. (2007) · Journal of Virology · doi:10.1128/jvi.00016-07 · Cited by 100 · see citing works

Human Blood-Brain Barrier Disruption by Retroviral-Infected Lymphocytes: Role of Myosin Light Chain Kinase in Endothelial Tight-Junction Disorganization

Afonso, P. V., Ozden, S., Prévost, M., Schmitt, C., Seilhean, D., Weksler, B. B., Couraud, P., Antoine Gessain, A., Romero, I. A., & Ceccaldi, P. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.4.2576 · Cited by 97 · see citing works

West Nile virus: crossing the blood-brain barrier

Diamond, M., & Klein, R. S. (2004) · Nature Medicine · doi:10.1038/nm1204-1294 · Cited by 91 · see citing works

Hypoxia activates matrix metalloproteinase expression and the VEGF system in monkey choroid-retinal endothelial cells: Involvement of cytosolic phospholipase A2 activity.

Ottino, P., Finley, J., Rojo–Niersbach, E. G., Ottlecz, A., Lambrou, G. N., Bazán, H. E. P., & Bazan, N. G. (2004) · PubMed · Cited by 85 · see citing works

Polyomavirus JC infects human brain microvascular endothelial cells independent of serotonin receptor 2A

Chapagain, M. L., Verma, S., Mercier, F., Yanagihara, R. T., & Nerurkar, V. R. (2007) · Virology · doi:10.1016/j.virol.2007.02.018 · Cited by 81 · see citing works

West Nile Virus Envelope Protein Inhibits dsRNA-Induced Innate Immune Responses

Arjona, A., Ledizet, M., Anthony, K., Bonafé, N., Modis, Y., Town, T., & Fikrig, E. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.12.8403 · Cited by 76 · see citing works

Production of MMPs in Human Cerebral Endothelial Cells and Their Role in Shedding Adhesion Molecules

Hummel, V., Kallmann, B. A., Wagner, S., Fuller, T., Bayas, A., Tonn, J.-C., Benveniste, E. N., Toyka, K. V., & Rieckmann, P. (2001) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/60.4.320 · Cited by 76 · see citing works

Human immunodeficiency virus type-1 Nef protein induces blood–brain barrier disruption in the rat: role of matrix metalloproteinase-9

Sporer, B., Koedel, U., Paul, R. H., Kohleisen, B., Erfle, V., Fontana, A., & Pfister, H. (2000) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(99)00170-8 · Cited by 75 · see citing works

Herpes-simplex virus encephalitis is characterized by an early MMP-9 increase and collagen type IV degradation

Sellner, J., Simon, F., Meyding‐Lamadé, U., & Leib, S. L. (2006) · Brain Research · doi:10.1016/j.brainres.2006.09.093 · Cited by 68 · see citing works

Stromelysin-1 and gelatinase A are upregulated before TNF-α in LPS-stimulated neuroinflammation

Mun-Bryce, S., Lukes, A., Wallace, J. A., Lukes-Marx, M., & Rosenberg, G. A. (2002) · Brain Research · doi:10.1016/s0006-8993(02)02303-x · Cited by 67 · see citing works

Effect of synthetic matrix metalloproteinase inhibitors on lipopolysaccharide-induced blood–brain barrier opening in rodents: Differences in response based on strains and solvents

Rosenberg, G. A., Estrada, E. Y., & Mobashery, S. (2006) · Brain Research · doi:10.1016/j.brainres.2006.11.041 · Cited by 59 · see citing works

WEST NILE VIRUS INFECTION OF PRIMARY MOUSE NEURONAL AND NEUROGLIAL CELLS: THE ROLE OF ASTROCYTES IN CHRONIC INFECTION

Diniz, J. A. P., da Rosa, A. P. A. T., Guzmán, H., Xu, F., Xiao, S., Popov, V. L., Vasconcelos, P. F. C., & Tesh, R. B. (2006) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2006.75.691 · Cited by 58 · see citing works

Early Upregulation of Matrix Metalloproteinases Following Reperfusion Triggers Neuroinflammatory Mediators in Brain Ischemia in Rat

Amantea, D., Russo, R., Gliozzi, M., Fratto, V., Berliocchi, L., Bagetta, G., Bernardi, G., & Corasaniti, M. T. (2007) · International review of neurobiology · doi:10.1016/s0074-7742(07)82008-3 · Cited by 56 · see citing works

JC virus induces altered patterns of cellular gene expression: Interferon-inducible genes as major transcriptional targets

Verma, S., Ziegler, K., Ananthula, P., Co, J. K. G., Frisque, R. J., Yanagihara, R. T., & Nerurkar, V. R. (2005) · Virology · doi:10.1016/j.virol.2005.10.012 · Cited by 51 · see citing works

Elevated Levels of Matrix Metalloproteinase 9 and Tissue Inhibitor of Metalloproteinase 1 during the Acute Phase of Kawasaki Disease

Chua, P. K., Melish, M. E., Yu, Q., Yanagihara, R. T., Yamamoto, K., & Nerurkar, V. R. (2003) · Clinical and Vaccine Immunology · doi:10.1128/cdli.10.2.308-314.2003 · Cited by 49 · see citing works

In vitro effects of selenium deficiency on West Nile virus replication and cytopathogenicity

Verma, S., Molina, Y., Lo, Y. Y., Cropp, B. C., Nakano, C., Yanagihara, R. T., & Nerurkar, V. R. (2008) · Virology Journal · doi:10.1186/1743-422x-5-66 · Cited by 35 · see citing works

Matrix metalloproteinase‐1 activates a pertussis toxin‐sensitive signaling pathway that stimulates the release of matrix metalloproteinase‐9

Conant, K. E., Haughey, N. J., Nath, A., Hillaire, C. S., Gary, D. S., Pardo, C. A., Wahl, L. M., Bilak, M. M., Milward, E. A., & Mattson, M. P. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01038.x · Cited by 33 · see citing works

Association of plasminogen activators and matrix metalloproteinase‐9 proteolytic cascade with blood–CNS barrier damage of angiostrongyliasis

Chen, K., Liu, J.-Y., Lai, S., Hsu, L., & Lee, H.-H. (2006) · International Journal of Experimental Pathology · doi:10.1111/j.0959-9673.2006.00459.x · Cited by 28 · see citing works

The role of tumor necrosis factor in modulating responses of murine embryo fibroblasts by flavivirus, West Nile

Cheng, Y., King, N. J. C., & Kesson, A. M. (2004) · Virology · doi:10.1016/j.virol.2004.06.050 · Cited by 28 · see citing works

Inhibition of matrix metalloproteinases ameliorates blood–brain barrier disruption and neuropathological lesions caused by avirulent Semliki Forest virus infection

Keogh, B., Sheahan, B. J., Atkins, G. J., & Mills, K. H. G. (2003) · Veterinary Immunology and Immunopathology · doi:10.1016/s0165-2427(03)00082-5 · Cited by 13 · see citing works

Role for peroxisome proliferator-activated receptor-gamma in Alzheimer's disease.

van Geel (2001) · Open Repository and Bibliography (University of Luxembourg) · doi:10.1002/1531-8249(20010201)49:2 · Cited by 7 · see citing works

Untitled work

Kordower (1999) · doi:10.1002/1531-8249(199909)46:3

Blood-Brain Barrier: From Physiology to Disease and Back

Sweeney, M. D., Zhao, Z., Montagne, A., Nelson, A. R., & Zlokovic, B. V. (2019) · Physiological Reviews · doi:10.1152/physrev.00050.2017 · Cited by 2,294 · see citing works

Modern methods for delivery of drugs across the blood–brain barrier

Chen, Y., & Liu, L. (2011) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2011.11.010 · Cited by 1,005 · see citing works

Virus Infections in the Nervous System

Koyuncu, O. O., Hogue, I. B., & Enquist, L. W. (2013) · Cell Host & Microbe · doi:10.1016/j.chom.2013.03.010 · Cited by 594 · see citing works

West Nile virus infection and immunity

Suthar, M. S., Diamond, M., & Gale, M. (2013) · Nature Reviews Microbiology · doi:10.1038/nrmicro2950 · Cited by 432 · see citing works

Occludin: One Protein, Many Forms

Cummins, P. M. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.06029-11 · Cited by 409 · see citing works

MMP ‐9 in translation: from molecule to brain physiology, pathology, and therapy

Vafadari, B., Salamian, A., & Kaczmarek, L. (2015) · Journal of Neurochemistry · doi:10.1111/jnc.13415 · Cited by 381 · see citing works

Claudins and Other Tight Junction Proteins

Günzel, D., & Fromm, M. (2012) · Comprehensive physiology · doi:10.1002/cphy.c110045 · Cited by 401 · see citing works

Illuminating viral infections in the nervous system

McGavern, D. B., & Kang, S. S. (2011) · Nature Reviews Immunology · doi:10.1038/nri2971 · Cited by 281 · see citing works

T cell responses in the central nervous system

Korn, T., & Kallies, A. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2016.144 · Cited by 268 · see citing works

Viral Pathogen-Associated Molecular Patterns Regulate Blood-Brain Barrier Integrity via Competing Innate Cytokine Signals

Daniels, B. P., Holman, D. W., Cruz-Orengo, L., Jujjavarapu, H., Durrant, D. M., & Klein, R. S. (2014) · mBio · doi:10.1128/mbio.01476-14 · Cited by 235 · see citing works

Viral disruption of the blood–brain barrier

Spindler, K. R., & Hsu, T.-H. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.03.009 · Cited by 219 · see citing works

West Nile Virus: An Update on Pathobiology, Epidemiology, Diagnostics, Control and “One Health” Implications

Habarugira, G., Suen, W. W., Hobson‐Peters, J., Hall, R. A., & Bielefeldt‐Ohmann, H. (2020) · Pathogens · doi:10.3390/pathogens9070589 · Cited by 220 · see citing works

West Nile virus-induced disruption of the blood–brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

Roe, K., Kumar, M., Lum, S., Orillo, B., Nerurkar, V. R., & Verma, S. (2012) · Journal of General Virology · doi:10.1099/vir.0.040899-0 · Cited by 184 · see citing works

2′-O Methylation of the Viral mRNA Cap by West Nile Virus Evades Ifit1-Dependent and -Independent Mechanisms of Host Restriction In Vivo

Szretter, K. J., Daniels, B. P., Cho, H., Gainey, M. D., Yokoyama, W. M., Gale, M., Virgin, H. W., Klein, R. S., Sen, G. C., & Diamond, M. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002698 · Cited by 168 · see citing works

Pathways Exploited by Flaviviruses to Counteract the Blood-Brain Barrier and Invade the Central Nervous System

Mustafá, Y. M., Meuren, L. M., Coelho, S. V. A., & de Arruda, L. B. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.00525 · Cited by 136 · see citing works

Zika Virus Infects Human Sertoli Cells and Modulates the Integrity of the In Vitro Blood-Testis Barrier Model

Siemann, D. N., Strange, D. P., Maharaj, P. N., Shi, P., & Verma, S. (2017) · Journal of Virology · doi:10.1128/jvi.00623-17 · Cited by 135 · see citing works

Disruption of the blood brain barrier is vital property of neurotropic viral infection of the central nervous system

Al‐Obaidi, M. M. J., Bahadoran, A., Wang, S., Manikam, R., Raju, C. S., & Sekaran, S. D. (2018) · Acta Virologica · doi:10.4149/av_2018_102 · Cited by 134 · see citing works

West Nile Virus: Immunity and Pathogenesis

Lim, S. M., Koraka, P., Osterhaus, A. D. M. E., & Martina, B. E. E. (2011) · Viruses · doi:10.3390/v3060811 · Cited by 133 · see citing works

Encephalitic Arboviruses: Emergence, Clinical Presentation, and Neuropathogenesis

Salimi, H., Cain, M. D., & Klein, R. (2016) · Neurotherapeutics · doi:10.1007/s13311-016-0443-5 · Cited by 108 · see citing works

Mechanism of West Nile Virus Neuroinvasion: A Critical Appraisal

Suen, W. W., Prow, N. A., Hall, R. A., & Bielefeldt‐Ohmann, H. (2014) · Viruses · doi:10.3390/v6072796 · Cited by 123 · see citing works

Pro-inflammatory cytokines derived from West Nile virus (WNV)-infected SK-N-SH cells mediate neuroinflammatory markers and neuronal death

Kumar, M., Verma, S., & Nerurkar, V. R. (2010) · Journal of Neuroinflammation · doi:10.1186/1742-2094-7-73 · Cited by 122 · see citing works

Disruption of in vitro endothelial barrier integrity by J apanese encephalitis virus‐Infected astrocytes

Chang, C., Li, J., Chen, W., Ou, Y., Lai, C., Hu, Y., Wu, C., Chang, C., & Chen, C. (2015) · Glia · doi:10.1002/glia.22857 · Cited by 120 · see citing works

Viral Encephalitis and Neurologic Diseases: Focus on Astrocytes

Soung, A., & Klein, R. S. (2018) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2018.09.001 · Cited by 116 · see citing works

Mechanisms of restriction of viral neuroinvasion at the blood–brain barrier

Miner, J. J., & Diamond, M. (2015) · Current Opinion in Immunology · doi:10.1016/j.coi.2015.10.008 · Cited by 115 · see citing works

Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

Kumar, M., Roe, K., Orillo, B., Muruve, D. A., Nerurkar, V. R., Gale, M., & Verma, S. (2013) · Journal of Virology · doi:10.1128/jvi.02667-12 · Cited by 113 · see citing works

Infection of Pericytes In Vitro by Japanese Encephalitis Virus Disrupts the Integrity of the Endothelial Barrier

Chen, C., Ou, Y., Li, J., Chang, C.-Y., Pan, H.-C., Lai, C.-Y., Liao, S., Raung, S., & Chang, C.-J. (2013) · Journal of Virology · doi:10.1128/jvi.02738-13 · Cited by 108 · see citing works

Tick-borne encephalitis virus infects human brain microvascular endothelial cells without compromising blood-brain barrier integrity

Palus, M., Vancová, M., Širmarová, J., Elsterová, J., Perner, J., & Růžek, D. (2017) · Virology · doi:10.1016/j.virol.2017.04.012 · Cited by 95 · see citing works

Flaviviruses are neurotropic, but how do they invade the CNS?

Neal, J. (2014) · Journal of Infection · doi:10.1016/j.jinf.2014.05.010 · Cited by 91 · see citing works

Flaviviruses and the Central Nervous System: Revisiting Neuropathological Concepts

Maximova, O. A., & Pletnev, A. G. (2018) · Annual Review of Virology · doi:10.1146/annurev-virology-092917-043439 · Cited by 90 · see citing works

Astrocytes in Flavivirus Infections

Potokar, M., Jorgačevski, J., & Zorec, R. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030691 · Cited by 84 · see citing works

VEGFR2 and Src Kinase Inhibitors Suppress Andes Virus-Induced Endothelial Cell Permeability

Gorbunova, E. E., Gavrilovskaya, I. N., Pepini, T., & Mackow, E. R. (2010) · Journal of Virology · doi:10.1128/jvi.02319-10 · Cited by 82 · see citing works

Targeting Host Factors to Treat West Nile and Dengue Viral Infections

Krishnan, M. N., & García-Blanco, M. A. (2014) · Viruses · doi:10.3390/v6020683 · Cited by 80 · see citing works

Dengue Virus Infection of Blood–Brain Barrier Cells: Consequences of Severe Disease

Calderón-Peláez, M.-A., Velandia-Romero, M. L., Bastidas-Legarda, L. Y., Beltrán, E. O., Camacho-Ortega, S. J., & Castellanos, J. E. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.01435 · Cited by 83 · see citing works

West Nile Virus-Induced Cell Adhesion Molecules on Human Brain Microvascular Endothelial Cells Regulate Leukocyte Adhesion and Modulate Permeability of the In Vitro Blood-Brain Barrier Model

Roe, K., Orillo, B., & Verma, S. (2014) · PLoS ONE · doi:10.1371/journal.pone.0102598 · Cited by 75 · see citing works

Reduced immune cell infiltration and increased pro-inflammatory mediators in the brain of Type 2 diabetic mouse model infected with West Nile virus

Kumar, M., Roe, K., Nerurkar, P. V., Orillo, B., Thompson, K. S., Verma, S., & Nerurkar, V. R. (2014) · Journal of Neuroinflammation · doi:10.1186/1742-2094-11-80 · Cited by 74 · see citing works

The Causes and Long-Term Consequences of Viral Encephalitis

Böhmwald, K., Andrade, C. A., Gálvez, N. M. S., Mora, V. P., Muñóz, J. T., & Kalergis, A. M. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.755875 · Cited by 73 · see citing works

Immune Responses to West Nile Virus Infection in the Central Nervous System

Cho, H., & Diamond, M. (2012) · Viruses · doi:10.3390/v4123812 · Cited by 73 · see citing works

IL-22 Signaling Contributes to West Nile Encephalitis Pathogenesis

Wang, P., Bai, F., Zenewicz, L. A., Dai, J., Gate, D., Cheng, G., Yang, L., Qian, F., Yuan, X., Montgomery, R. R., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044153 · Cited by 71 · see citing works

Dynamics of expression patterns of AQP4, dystroglycan, agrin and matrix metalloproteinases in human glioblastoma

Noell, S., Wolburg‐Buchholz, K., Mack, A. F., Ritz, R., Tatagiba, M. S., Beschorner, R., Wolburg, H., & Fallier‐Becker, P. (2012) · Cell and Tissue Research · doi:10.1007/s00441-011-1321-4 · Cited by 66 · see citing works

Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4

Lai, C.-Y., Strange, D. P., Wong, T. A. S., Lehrer, A. T., & Verma, S. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01571 · Cited by 66 · see citing works

MMPs and ADAMs in neurological infectious diseases and multiple sclerosis

Muri, L., Leppert, D., Grandgirard, D., & Leib, S. L. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03174-6 · Cited by 64 · see citing works

West Nile Virus Infection Causes Endocytosis of a Specific Subset of Tight Junction Membrane Proteins

Xu, Z., Waeckerlin, R. C., Urbanowski, M. D., van Marle, G., & Hobman, T. C. (2012) · PLoS ONE · doi:10.1371/journal.pone.0037886 · Cited by 64 · see citing works

Neurotropic Viruses, Astrocytes, and COVID-19

Verdev, P. T., Potokar, M., Kolenc, M., Korva, M., Avšič‐Županc, T., Zorec, R., & Jorgačevski, J. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.662578 · Cited by 65 · see citing works

Differential Replication of Pathogenic and Nonpathogenic Strains of West Nile Virus within Astrocytes

Hussmann, K. L., Samuel, M. A., Kim, K. S., Diamond, M., & Fredericksen, B. L. (2012) · Journal of Virology · doi:10.1128/jvi.02577-12 · Cited by 62 · see citing works

IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia

Severance, E. G., Gressitt, K. L., Alaedini, A., Rohleder, C., Enning, F., Bumb, J. M., Müller, J. K., Schwarz, E., Yolken, R. H., & Leweke, F. M. (2014) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2014.09.009 · Cited by 59 · see citing works

Death Receptor-Mediated Apoptotic Signaling Is Activated in the Brain following Infection with West Nile Virus in the Absence of a Peripheral Immune Response

Clarke, P., Leser, J. S., Quick, E. D., Dionne, K. R., Beckham, J. D., & Tyler, K. L. (2013) · Journal of Virology · doi:10.1128/jvi.02944-13 · Cited by 59 · see citing works

Neurocognitive impacts of arbovirus infections

Clé, M., Eldin, P., Briant, L., Lannuzel, A., Simonin, Y., Van de Perre, P., Cabié, A., & Salinas, S. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-020-01904-3 · Cited by 67 · see citing works

Clinical implications of leukocyte infiltration at the choroid plexus in (neuro)inflammatory disorders

Demeestere, D., Libert, C., & Vandenbroucke, R. E. (2015) · Drug Discovery Today · doi:10.1016/j.drudis.2015.05.003 · Cited by 57 · see citing works

In Vitro Infection with Dengue Virus Induces Changes in the Structure and Function of the Mouse Brain Endothelium

Velandia-Romero, M. L., Calderón-Peláez, M.-A., & Castellanos, J. E. (2016) · PLoS ONE · doi:10.1371/journal.pone.0157786 · Cited by 55 · see citing works

Japanese Encephalitis Virus Disrupts Cell-Cell Junctions and Affects the Epithelial Permeability Barrier Functions

Agrawal, T., Sharvani, V., Nair, D., & Medigeshi, G. R. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069465 · Cited by 53 · see citing works

Disruption of the Blood-Brain Barrier During Neuroinflammatory and Neuroinfectious Diseases

Salimi, H., & Klein, R. S. (2019) · Contemporary clinical neuroscience · doi:10.1007/978-3-030-19515-1_7 · Cited by 54 · see citing works

Brain Infection by Hepatitis E Virus Probably via Damage of the Blood-Brain Barrier Due to Alterations of Tight Junction Proteins

Tian, J., Shi, R., Liu, T., She, R., Wu, Q., An, J., Hao, W., & Soomro, M. H. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00052 · Cited by 52 · see citing works

Viral nervous necrosis virus persistently replicates in the central nervous system of asymptomatic gilthead seabream and promotes a transient inflammatory response followed by the infiltration of IgM+ B lymphocytes

López‐Muñoz, A., Sepulcre, M. P., García‐Moreno, D., Fuentes, I., Béjar, J., Manchado, M., Álvarez, M. C., Meseguer, J., & Mulero, V. (2012) · Developmental & Comparative Immunology · doi:10.1016/j.dci.2012.02.007 · Cited by 51 · see citing works

Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses

de Vries, L., & Harding, A. T. (2023) · Viruses · doi:10.3390/v15020261 · Cited by 48 · see citing works

Diverse microbial interactions with the basement membrane barrier

Steukers, L., Glorieux, S., Vandekerckhove, A. P., Favoreel, H. W., & Nauwynck, H. (2012) · Trends in Microbiology · doi:10.1016/j.tim.2012.01.001 · Cited by 49 · see citing works

Immune Functions of Astrocytes in Viral Neuroinfections

Jorgačevski, J., & Potokar, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043514 · Cited by 48 · see citing works

Molecular mechanisms of neuroinflammation and injury during acute viral encephalitis

Shives, K. D., Tyler, K. L., & Beckham, J. D. (2017) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2017.03.006 · Cited by 47 · see citing works

Regulation of Human Brain Microvascular Endothelial Cell Adhesion and Barrier Functions by Memantine

Wang, F., Zou, Z., Gong, Y., Yuan, D., Chen, X., & Sun, T. (2017) · Journal of Molecular Neuroscience · doi:10.1007/s12031-017-0917-x · Cited by 47 · see citing works

Innate immune interactions within the central nervous system modulate pathogenesis of viral infections

Nair, S., & Diamond, M. (2015) · Current Opinion in Immunology · doi:10.1016/j.coi.2015.06.011 · Cited by 44 · see citing works

Combined treatment of adenosine nucleoside inhibitor NITD008 and histone deacetylase inhibitor vorinostat represents an immunotherapy strategy to ameliorate West Nile virus infection

Nelson, J., Roe, K., Orillo, B., Shi, P., & Verma, S. (2015) · Antiviral Research · doi:10.1016/j.antiviral.2015.07.008 · Cited by 43 · see citing works

Elevation of Matrix Metalloproteinase-9 Level in Cerebrospinal Fluid of Tick-Borne Encephalitis Patients Is Associated with IgG Extravassation and Disease Severity

Kang, X., Li, Y., Wei, J., Zhang, Y., Bian, C., Wang, K., Wu, X., Hu, Y., Li, J., & Yang, Y. (2013) · PLoS ONE · doi:10.1371/journal.pone.0077427 · Cited by 43 · see citing works

Differential neurovirulence of Usutu virus lineages in mice and neuronal cells

Clé, M., Constant, O., Barthelemy, J., Desmetz, C., Martin, M. F., Lapeyre, L., Cadar, D., Savini, G., Teodori, L., Monaco, F., et al. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-020-02060-4 · Cited by 41 · see citing works

Titanium dioxide nanoparticles exaggerate respiratory syncytial virus-induced airway epithelial barrier dysfunction

Smallcombe, C. C., Harford, T. J., Linfield, D. T., Lechuga, S., Bokun, V., Piedimonte, G., & Rezaee, F. (2020) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00104.2020 · Cited by 37 · see citing works

Claudins and Other Tight Junction Proteins

Günzel, D., & Fromm, M. (2012) · Comprehensive physiology · doi:10.1002/j.2040-4603.2012.tb00450.x · Cited by 37 · see citing works

Role of Dendritic Cells in Viral Brain Infections

Constant, O., Maarifi, G., Blanchet, F. P., Van de Perre, P., Simonin, Y., & Salinas, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.862053 · Cited by 35 · see citing works

Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes

Verma, S., Kumar, M., & Nerurkar, V. R. (2010) · Journal of General Virology · doi:10.1099/vir.0.026716-0 · Cited by 34 · see citing works

Transcriptome analysis reveals temperature-regulated antiviral response in turbot Scophthalmus maximus

Zhang, J., & Sun, L. (2017) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2017.07.038 · Cited by 32 · see citing works

Claudins in viral infection: from entry to spread

Colpitts, C. C., & Baumert, T. F. (2016) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-016-1908-4 · Cited by 31 · see citing works

A Journey to the Central Nervous System: Routes of Flaviviral Neuroinvasion in Human Disease

Marshall, E. M., Koopmans, M., & Rockx, B. (2022) · Viruses · doi:10.3390/v14102096 · Cited by 31 · see citing works

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood–brain barrier

Volle, R., Weksler, B. B., Romero, I. A., Couraud, P., Archimbaud, C., Henquell, C., Pereira, B., Peigue‐Lafeuille, H., Bailly, J., & Mirand, A. (2015) · Journal of General Virology · doi:10.1099/vir.0.000103 · Cited by 29 · see citing works

An insight into the ligand–receptor interactions involved in the translocation of pathogens across blood–brain barrier

Bencúrová, E., Mlynárčik, P., & Bhide, M. R. (2011) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2011.00867.x · Cited by 28 · see citing works

Differential induction of CCL5 by pathogenic and non-pathogenic strains of West Nile virus in brain endothelial cells and astrocytes

Hussmann, K. L., & Fredericksen, B. L. (2014) · Journal of General Virology · doi:10.1099/vir.0.060558-0 · Cited by 28 · see citing works

The neuroimmune response to West Nile virus

Fredericksen, B. L. (2013) · Journal of NeuroVirology · doi:10.1007/s13365-013-0180-z · Cited by 27 · see citing works

Rotavirus infection-associated central nervous system complications: clinicoradiological features and potential mechanisms

Lee, K. Y. (2022) · Korean Journal of Pediatrics · doi:10.3345/cep.2021.01333 · Cited by 26 · see citing works

Vascular permeability in the brain is a late pathogenic event during Rift Valley fever virus encephalitis in rats

Walters, A. W., Kujawa, M. R., Albe, J. R., Reed, D. S., Klimstra, W. B., & Hartman, A. L. (2018) · Virology · doi:10.1016/j.virol.2018.10.021 · Cited by 26 · see citing works

Inflammation in neuroviral diseases

Giraudon, P., & Bernard, A. (2010) · Journal of Neural Transmission · doi:10.1007/s00702-010-0402-y · Cited by 25 · see citing works

Viral interactions with the blood-brain barrier: old dog, new tricks

Hou, J., Baker, L. A., Zhou, L., & Klein, R. S. (2016) · Tissue Barriers · doi:10.1080/21688370.2016.1142492 · Cited by 24 · see citing works

Innate host responses to West Nile virus: Implications for central nervous system immunopathology

Rossini, G. (2013) · World Journal of Virology · doi:10.5501/wjv.v2.i2.49 · Cited by 24 · see citing works

Biological significance and pathophysiological role of Matrix Metalloproteinases in the Central Nervous System

Ganguly, K., Adhikary, K., Acharjee, A., Acharjee, P., Trigun, S. K., Mutlaq, A. S., Ashique, S., Yasmin, S., Alshahrani, A. M., & Ansari, M. Y. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.135967 · Cited by 23 · see citing works

Polarization of Type 1 Macrophages Is Associated with the Severity of Viral Encephalitis Caused by Japanese Encephalitis Virus and Dengue Virus

Jhan, M.-K., Chen, C., Shen, T., Tseng, P., Wang, Y.-T., Satria, R. D., Yu, C.-Y., & Lin, C. (2021) · Cells · doi:10.3390/cells10113181 · Cited by 24 · see citing works

Role of neuroinflammation mediated potential alterations in adult neurogenesis as a factor for neuropsychiatric symptoms in Post-Acute COVID-19 syndrome—A narrative review

Karthik, S., Saraswathi, I., Alarifi, A., Al-Atram, A. A., Mickeymaray, S., Paramasivam, A., Shaikh, S., Jeraud, M., & Alothaim, A. S. (2022) · PeerJ · doi:10.7717/peerj.14227 · Cited by 23 · see citing works

Portals of Viral Entry into the Central Nervous System

Swanson, P. A., & McGavern, D. B. (2015) · CRC Press eBooks · doi:10.1201/b19299-3 · Cited by 21 · see citing works

Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil

Junior, I. P. D. S., dos Santos, F. B., de Paula, V. S., Vieira, T. C. R. G., Dias, H. G., Barros, C. A., & da Silva, E. E. (2021) · Viruses · doi:10.3390/v13071370 · Cited by 20 · see citing works

In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment

Chesnut, M., Munoz-Arcos, L. S., Harris, G., Freeman, D. M., Gama, L., Pardo, C. A., & Pamies, D. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00223 · Cited by 20 · see citing works

Matrix metalloproteinase-9 (MMP-9): A macromolecular mediator in CNS infections: A review

Mubarak, M. M., Baba, I. A., Wani, Z. A., Kantroo, H. A., & Ahmad, Z. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.143902 · Cited by 20 · see citing works

Development of peptides targeting receptor binding site of the envelope glycoprotein to contain the West Nile virus infection

Petroušková, P., Mochnáčová, E., Bhide, K., Kulkarni, A. D., Tkáčová, Z., Hruškovicová, J., & Bhide, M. R. (2021) · Scientific Reports · doi:10.1038/s41598-021-99696-w · Cited by 18 · see citing works

Claudins and pathogenesis of viral infection

Tawar, R. G., Colpitts, C. C., Lupberger, J., Saghire, H. E., Zeisel, M. B., & Baumert, T. F. (2015) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2015.04.011 · Cited by 18 · see citing works

Metabolic response to CNS infection with flaviviruses

Dobrzyńska, M., Moniuszko-Malinowska, A. M., & Skrzydlewska, E. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02898-4 · Cited by 17 · see citing works

Neuroinvasion by Chandipura virus

Rajasekharan, S., Rana, J., Gulati, S., Gupta, V., & Gupta, S. (2014) · Acta Tropica · doi:10.1016/j.actatropica.2014.03.028 · Cited by 15 · see citing works

Regulation of pathological blood-brain barrier for intracranial enhanced drug delivery and anti-glioblastoma therapeutics

Wang, K., Zhang, F., WEN, C., HUANG, Z., ZHANG, Y., HU, Z., HU, F., & Wen, L. (2021) · Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics · doi:10.32604/or.2022.025696 · Cited by 14 · see citing works

Structural proteins of West Nile virus are a major determinant of infectious particle production and fitness in astrocytes

Hussmann, K. L., Vandergaast, R., Zheng, K., Hoover, L. I., & Fredericksen, B. L. (2014) · Journal of General Virology · doi:10.1099/vir.0.065474-0 · Cited by 15 · see citing works

Rift Valley fever virus is able to cross the human blood–brain barrier in vitro by direct infection with no deleterious effects

Quellec, J., Piro-Mégy, C., Cannac, M., Nisole, S., Marty, F. H., Gosselet, F., Shimizu, F., Kanda, T., Cêtre-Sossah, C. B., & Salinas, S. (2024) · Journal of Virology · doi:10.1128/jvi.01267-24 · Cited by 14 · see citing works

A central role for CCR2 in monocyte recruitment and blood–brain barrier disruption during Usutu virus encephalitis

Slowikowski, E., Willems, C., Lemes, R. M. R., Schuermans, S., Berghmans, N., Rocha, R. D. P. F., Martens, E., Proost, P., Delang, L., Marques, R. E., et al. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03435-1 · Cited by 14 · see citing works

Portals of Viral Entry into the Central Nervous System

McGavern, P. A. S. I. A. D. B. (2015) · CRC Press eBooks · doi:10.1201/b19299-5 · Cited by 13 · see citing works

Induction of virus-specific effector immune cell response limits virus replication and severe disease in mice infected with non-lethal West Nile virus Eg101 strain

Kumar, M., Roe, K., O’Connell, M., & Nerurkar, V. R. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0400-y · Cited by 13 · see citing works

Potential of exosomes for targeted therapy in neuroinfectious disease management: crossing the blood–brain barrier

Bukke, S. P. N., Yadav, S., Prajapati, S., Rani, S. S., Reddy, M. S., Thalluri, C., Chettupalli, A. K., Goruntla, N., Pradeepkumar, B., Eftekhari, Z., et al. (2025) · Tissue Barriers · doi:10.1080/21688370.2025.2607157 · Cited by 12 · see citing works

Viruses and the Brain—A Relationship Prone to Trouble

Mielcarska, M. B., & Rouse, B. T. (2025) · Viruses · doi:10.3390/v17020203 · Cited by 12 · see citing works

Usutu virus and West Nile virus use a transcellular route of neuroinvasion across an in vitro model of the human blood–brain barrier

Marshall, E. M., Koopmans, M., & Rockx, B. (2024) · npj Viruses · doi:10.1038/s44298-024-00034-4 · Cited by 11 · see citing works

Unraveling the complex interplay: immunopathology and immune evasion strategies of alphaviruses with emphasis on neurological implications

Souza, R. D. O., Júnior, J. W. B. D., Casa, V. S. D., Rosa, D. S., Rénia, L., & Claser, C. (2024) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2024.1421571 · Cited by 11 · see citing works

In Vitro Blood-Brain Barrier Models for Neuroinfectious Diseases: A Narrative Review

Badawi, A. H. J., Mohamad, N. A., Stanslas, J., Kirby, B. P., Neela, V. K., Ramasamy, R., & Basri, H. (2023) · Current Neuropharmacology · doi:10.2174/1570159x22666231207114346 · Cited by 12 · see citing works

Characterization of the markers of blood-brain barrier disruption in West Nile virus infected mice

Roe, K. (2011) · ScholarSpace (University of Hawaii at Manoa)

West Nile virus-induced disruption of the blood–brain barrier in mice is characterized by the degradation of the junctional complex proteins and increase in multiple matrix metalloproteinases

Roe, K., Kumar, M., Lum, S., Orillo, B., Nerurkar, V. R., & Verma, S. (2012) · Journal of General Virology · doi:10.1099/vir.0.040899-0 · Cited by 184 · see citing works

Matrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain

Wang, P., Dai, J., Bai, F., Kong, K., Wong, S. J., Montgomery, R. R., Madri, J. A., & Fikrig, E. (2008) · Journal of Virology · doi:10.1128/jvi.00314-08 · Cited by 186 · see citing works

West Nile virus infection modulates human brain microvascular endothelial cells tight junction proteins and cell adhesion molecules: Transmigration across the in vitro blood-brain barrier

Verma, S., Lo, Y. Y., Chapagain, M. L., Lum, S., Kumar, M., Gurjav, U., Luo, H., Nakatsuka, A. S., & Nerurkar, V. R. (2009) · Virology · doi:10.1016/j.virol.2008.11.047 · Cited by 255 · see citing works

In-vitro characterization of human brain microvascular endothelial cells infected with West Nile virus to study tight junction integrity

Lo, Y. Y. (2008) · ScholarSpace (University of Hawaii at Manoa)