Cited by 659Stress Responses and CortisolAnimal Behavior and Welfare StudiesAdrenal Hormones and Disorders

The DOI matches its Crossref record; 31 of the 31 references it cites were found in a registry or an index.

Analysis of endogenous cortisol concentrations in the hair of rhesus macaques

Davenport, Matthew D., Tiefenbacher, Stefan, Lutz, Corrine K., Novak, Melinda A., Meyer, Jerrold S.·2006·General and Comparative Endocrinology

DOI 10.1016/j.ygcen.2006.01.005

Open this paper in CoChat — free account

Abstract

Short-term changes in activity of the hypothalamic-pituitary-adrenocortical (HPA) system are routinely assessed by measuring glucocorticoid or metabolite concentrations in plasma, saliva, urine, or feces. However, there are no current methods for determining long-term (i.e., weeks or months) activity of this system. Herein, we describe the development and validation of a simple procedure for measuring cortisol concentrations in the hair of rhesus macaques. This procedure involves two brief isopropanol washes of the hair strands to remove surface contaminants, subsequent powdering of the washed and dried hair, a 24-h methanol extraction followed by evaporation of the solvent and reconstitution of the extract in assay buffer, and finally analysis of the extracted cortisol by a sensitive and specific enzyme immunoassay. Our results confirm the specificity of the procedure for cortisol, show that proximal and distal segments of hair do not differ in their cortisol concentration, and demonstrate that a significant and prolonged stressful experience produces a significant increase in hair cortisol. This new procedure should be valuable for assessing baseline HPA activity in nonhuman primates (and, with appropriate validation, in other species as well) over relatively long periods of time, and also for monitoring chronic stress that might be associated with various experimental manipulations.

Integrity signals

Registry

Crossref · 10.1016/j.ygcen.2006.01.005

Cites

31 of 31 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Guide for the Care and Use of Laboratory Animals: Eighth Edition
(2011) · doi:10.17226/12910 · Cited by 16,199
The 1996 Guide for the Care and Use of Laboratory Animals
Clark, J. D., Gebhart, G. F., Gonder, J. C., Keeling, M. E., & Kohn, D. F. (1997) · ILAR Journal · doi:10.1093/ilar.38.1.41 · Cited by 4,429
Salivary cortisol in psychoneuroendocrine research: recent developments and applications
Kirschbaum, C., & Hellhammer, D. H. (1994) · Psychoneuroendocrinology · doi:10.1016/0306-4530(94)90013-2 · Cited by 2,107
Transport of steroid hormones: binding of 21 endogenous steroids to both testosterone-binding globulin and corticosteroid-binding globulin in human plasma
DUNN, J. F., NISULA, B. C., & RODBARD, D. (1981) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-53-1-58 · Cited by 1,238
Potential problems with the interpretation of hair analysis results
Wennig, R. (2000) · Forensic Science International · doi:10.1016/s0379-0738(99)00146-2 · Cited by 677
Hair Analysis for Drugs of Abuse
Baumgartner, W., Hill, V., & BLAHD, W. H. (1989) · Journal of Forensic Sciences · doi:10.1520/jfs12787j · Cited by 473
Anatomy and physiology of hair
Harkey, M. R. (1993) · Forensic Science International · doi:10.1016/0379-0738(93)90255-9 · Cited by 380
Detection of physiological concentrations of cortisol and cortisone in human hair
Raul, J.-S., Cirimele, V., Ludes, B., & Kintz, P. (2004) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2004.02.010 · Cited by 348
Identification of ten corticosteroids in human hair by liquid chromatography–ionspray mass spectrometry
Cirimele, V., Kintz, P., Dumestre-Toulet, V., Goullé, J., & Ludes, B. (2000) · Forensic Science International · doi:10.1016/s0379-0738(99)00180-2 · Cited by 190
Testing Human Hair for Drugs of Abuse. II. Identification of Unique Cocaine Metabolites in Hair of Drug Abusers and Evaluation of Decontamination Procedures
Cone, E. J., Yousefnejad, D., Darwin, W. D., & Maguire, T. (1991) · Journal of Analytical Toxicology · doi:10.1093/jat/15.5.250 · Cited by 187

Show all 31 references

Research works printed but not linked: 1

Lutz, 2005, The effect of relocation on nighttime activity and salivary cortisol in singly-housed male Macaca mulatta with and without a record of self-injury, Am. J. Primatol., 66, 83

Sorted by citations

Items 501–600 of 656

Stress in Indoor and Outdoor Cats: Association between Hair Cortisol Levels, Housing Style, and Guardians’ Perceptions of Behavior
Lima, K. C. P., Fraga‐Silva, T. F. D. C., Borges, A. L. T. F., Neto, L. F. C., da Rocha, E. R., do Nascimento, T. G., & Santos, E. L. (2026) · Journal of Applied Animal Welfare Science · doi:10.1080/10888705.2025.2610233 · Cited by 3
War Exposure and Canine Cortisol Responses: Country Differences in Cortisol Profiles of Therapy Dogs
Foltin, S., Kostenko, S., Hartwig, A.-D., & Glenk, L. M. (2026) · Animals · doi:10.3390/ani16030381 · Cited by 3
“Subsequent extraction of cortisol was performed based on the protocol by Davenport, Tiefenbacher, Lutz, Novak, and Meyer (2006) [42].”
A Dozen Years of Baleen Hormones: Validations, Discoveries, Surprises, and Next Steps
Hunt, K. E., Jelincic, J., Lysiak, N. S. J., Stimmelmayr, R., Case, A., Evey, R. G., Ajó, A. F., Dillon, D. M., Reed, J., New, L., et al. (2026) · Integrative and Comparative Biology · doi:10.1093/icb/icag063 · Cited by 3
“However, in the early 2000s, endogenous hormones were reported to be detectable in vertebrate keratin tissues, first in mammalian hair ( Davenport et al. 2006 ) and secondly bird feathers ( Bortolotti et al. 2008 ), with concentrations that represent the animal’s endocrine state at the time when…”
Stress Physiology, Foraging, and Ecophysiology of Bats in Urban Environments
Korine, C., Oelbaum, P. J., & Muñoz‐Garcia, A. (2022) · Fascinating life sciences · doi:10.1007/978-3-031-13173-8_1 · Cited by 3
Technical validation and a comparison of two methods to quantify individual levels of glucocorticoids in Alpine marmot hair
Doss, E. M., Jouffroy, M., Rey, B., Cohas, A., von Hardenberg, A., & Smith, T. E. (2023) · MethodsX · doi:10.1016/j.mex.2023.102418 · Cited by 3
“Hair (180 mg) from both study 1 and 2 was mixed with 3.6 ml isopropanol in a glass tube (to remove contaminants) using a Heidolph Multi Reax test tube shaker at 800 rpm for 3 min [22] .”
Influential
Effects of administering local anesthesia immediately before surgical castration on indicators of pain and discomfort of beef calves
Bernier, A. F., Erickson, N., Campbell, J., & Moya, D. (2025) · Translational Animal Science · doi:10.1093/tas/txaf010 · Cited by 3
“…and cortisol levels is inconsistent in the literature (Otovic, 2014), with some studies reporting increased cortisol levels during chronic stress (Davenport et al., 2006), while others describing a blunted response of the hypothalamic-pituitary-adrenal axis, causing no response or reduced…”
Investigating hair cortisol dynamics in German Shepherd Dogs throughout pregnancy, lactation, and weaning phases, and its potential impact on the hair cortisol of offspring
Pan, C., Xu, S., Zhang, W., Zhao, Y., Song, M., & Zhao, J. (2025) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2025.106921 · Cited by 3
Packed-Nanofiber Solid-Phase Extraction Column for Determination of Cortisol in Hair Samples
Chen, L., Kang, X., Yan, Y., Gu, Z., & Lu, Z. (2012) · Chinese Journal of Analytical Chemistry · doi:10.1016/s1872-2040(11)60523-9 · Cited by 3
Corrélation des taux de cortisol dans le sérum, les poils et les fèces chez le dromadaire (Camelus dromedarius)
Bargaâ, R., Islah, L., Youssef, C., Abbadi, N. E., Belhouari, A., Hammoumi, A., Farh, M., Tahri, E. H., Riad, F., Mzibri, M. E., et al. (2016) · Revue d’élevage et de médecine vétérinaire des pays tropicaux · doi:10.19182/remvt.31184 · Cited by 3
“Chez les vertébrés, le stress a été évalué par l’analyse des hormones corticostéroïdes dans plusieurs matières telles que le sang, les fèces, les urines, la salive (Larter et Nagy, 2001 ; Van Der Staay et al., 2007 ; Saco et al., 2008) et les poils (Davenport et al., 2006).”
Background
Assaying progesterone, estradiol and cortisol concentrations in hair of Père David deer hinds: an alternative way to reflect seasonality of steroid secretion
Ping, X., Liu, N., Jiang, Z., Xu, H., Bai, J., Zhang, S., Zhong, Z., & Li, C. (2017) · Biological Rhythm Research · doi:10.1080/09291016.2017.1367063 · Cited by 3
“samples were washed to remove surface contamination based on validated methods from the published literature (Davenport et al. 2006; Macbeth et al. 2010).”
BackgroundMethodResultInfluential
To Provide a Double Feeder in Growing Pigs Housed under High Environmental Temperatures Reduces Social Interactions but Does Not Improve Weight Gains
Borges, T. D., Huerta‐Jimenez, M., Casal, N., González, J., Panella‐Riera, N., & Dalmau, A. (2020) · Animals · doi:10.3390/ani10122248 · Cited by 3
“Animals 2020, 10, 2248 5 of 20 Cortisol extraction was performed following the method of Davenport et al. (2006) [21] with minor modifications.”
BackgroundMethodInfluential
Índice de Temperatura y Humedad (THI) respaldado por el Cortisol Capilar en ganado lechero para la medición de Estrés Calórico Crónico
López-Quiñonez, E., Albarrán-Tamayo, F., Ramı́rez-Emiliano, J., Bañuelos-Hernández, B., & Cruz–Hernández, A. (2021) · Nova Scientia · doi:10.21640/ns.v13i27.2811 · Cited by 3
Hair and Claw Dehydroepiandrosterone Concentrations in Newborn Puppies Spontaneously Dead within 30 Days of Age
Fusi, J., Veronesi, M. C., Prandi, A., Meloni, T., Faustini, M., & Peric, T. (2022) · Animals · doi:10.3390/ani12223162 · Cited by 3
Assessing short-term feed efficiency and its association with biological markers in herbage-fed dairy cows
Haak, T., Münger, A., Kragten, S. A., Bruckmaier, R. M., Südekum, K., & Schori, F. (2024) · animal · doi:10.1016/j.animal.2024.101211 · Cited by 3
RETRACTED: Hair Cortisol and Fe-BARQ: Evaluating Chronic Stress and Behavior in Cats with Chronic Kidney Disease
Kim, G.-H., Lee, K., Choi, H.-S., Han, J. S., & Kim, S. (2025) · Animals · doi:10.3390/ani15060889 · Cited by 3
“Overall, 47 companion cats were recruited from a cat-only veterinary clinic in Seoul, South Korea.”
Retracted
Analysis of different biological matrices for glucocorticoid detection in wild Cervidae and Bovidae from Europe and North America: a review
Barukčić, V., Berlinguer, F., Pasciu, V., Sotgiu, F. D., & Šprem, N. (2025) · BMC Veterinary Research · doi:10.1186/s12917-025-04678-z · Cited by 6
“Davenport et al. [126] recommended washing the hair strand in 5 ml isopropanol to minimize the risk of extracting cortisol from the hair.”
Behavioral Ecology of Savanna Monkeys
Turner, T. R., Schmitt, C. A., & Cramer, J. D. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.009 · Cited by 3
Early childhood education and care context and cortisol from saliva and hair among 3–6-year-old children
Lehto, R., Lehto, E., Saha, M., Moazami-Goodarzi, A., Sääksjärvi, K., Leppänen, M. H., Vepsäläinen, H., Nissinen, K., Erkkola, M., & Sajaniemi, N. K. (2022) · Early Years Journal of International Research and Development · doi:10.1080/09575146.2022.2130879 · Cited by 3
“The protocol of Davenport et al. (2006) was used to extract steroids from the hair samples, and chemiluminescence immunoassay (IBL, Hamburg, Germany) was used to measure HCC.”
Method
Methodological Challenges and Clinical Applications of Hair Cortisol Analysis
Russell, E. (2012) · Scholarship@Western (Western University) · Cited by 3
A Reliable Procedure for Measuring Cortisol Levels in Rhesus Macaque Hair Samples
Li, C., Qin, D., Feng, X., Zhang, B., Yang, S., Hu, X., & Ma, Y. (2009) · Zoological Research · doi:10.3724/sp.j.1141.2009.04401 · Cited by 3
Measuring suffering
Cunningham, T. (2015) · Intervention · doi:10.1097/wtf.0000000000000073 · Cited by 3
Determination of estradiol and progesterone concentrations in human scalp hair
Kadour-Peero, E., Khoury, S., Awad, J., Shpritz, L., Chen-Konak, L., Shechner, C., & Saiegh, L. (2020) · Clinical and Experimental Obstetrics & Gynecology · doi:10.31083/j.ceog.2020.02.5206 · Cited by 3
A School-Based Progressive Muscle Relaxation Program for Female Adolescents: Development and the Effectiveness on Physiological and Psychological Evidence
Tsai, M.-L., Cheng, T., Yang, Y. K., & Wang, C. (2021) · Healthcare · doi:10.3390/healthcare9101319 · Cited by 6
Desarrollo de métodos rápidos para el análisis de residuos en producción animal
Gratacós-Cubarsí, M. (2008) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) · Cited by 3
Examining the Relationships Between Chronic Stress, HPA Axis Activity, and Depression in a Prospective and Longitudinal Study of Medical Internship
Mayer, S. E. (2017) · Deep Blue (University of Michigan) · Cited by 4
The validation of estradiol extraction and analysis from hairPreprint
Wang, W., van Dammen, L., Moody, S. N., Kiesner, J., Neiderhiser, J. M., Dismukes, A. R., Zhu, J., Constantinidis, C., & Shirtcliff, E. A. (2020) · doi:10.31234/osf.io/knuxs · Cited by 3
Hair Cortisol as a Predictive Biochemical Indicator for the Preventive and Personalised Evaluation of Suicide Risk in Depression? An Exploratory Comparison Study Between Mentally-Stable Control Subjects, Depressed Individuals and Individuals After Completing SuicidePreprint
Karabatsiakis, A., de Punder, K., Manrique, J.-S., Todt, M., & Dietrich, D. E. (2022) · Research Square · doi:10.21203/rs.3.rs-1882874/v1 · Cited by 3
Post-occupancy Evaluation at the Zoo: Behavioral and Hormonal Indicators of Welfare in Orangutans (Pongo pygmaeus abelii)
Tingey, L. (2000) · doi:10.15760/etd.901 · Cited by 3
“Hair assay validations have been carried out using samples obtained from laboratory animals (Davenport et al., 2006), domestic cats and dogs (Accorsi et al., 2008), and wildlife (Koren et al., 2002).”
Method
A novel paradigm in the prediction of the performance of breeding buffalo bulls: role of hair cortisol and testosterone
Gupta, A., Kumar, P., Bansal, K. N., Thakur, S., Yadav, U., Bala, R., Meel, M., Bishnoi, M. B., Bhardwaj, S., Verma, N., et al. (2025) · Tropical Animal Health and Production · doi:10.1007/s11250-025-04421-8 · Cited by 2
“Hair cortisol was extracted using a method described by Davenport et al. (2006) and modified by Tallo Para et al. (2015).”
Welfare implications of non-nutritive visits to an electronic feeder by pregnant gilts
Lagoda, M. E., Boyle, L. A., Marchewka, J., & O’Driscoll, K. (2025) · Applied Animal Behaviour Science · doi:10.1016/j.applanim.2025.106758 · Cited by 2
The role of human–pig interactions in modulating gut microbiota, stress, and performance
Venegas, L., Araya, C., Palomo, R., Galarce, N., Siel, D., Yañez, J. M., Correa‐Fiz, F., Calderón-Amor, J., Cartes, D., Ceballos, M. C., et al. (2025) · Porcine Health Management · doi:10.1186/s40813-025-00465-2 · Cited by 2
“The reconstituted samples were subsequently stored at -20 °C until analyzed using the Salimetrics Salivary Cortisol ELISA Kit (Salimetrics, State College, Pennsylvania, USA), which was validated to measure hair cortisol concentrations accurately [34].”
Stress-related challenges regarding the psychological health of police officers: The roles of perceived stress and physiological stress
Trépanier, M., Deschênes, A.-A., Marin, M., & Gendron, A. (2025) · Journal of Workplace Behavioral Health · doi:10.1080/15555240.2025.2579032 · Cited by 2
“Secondly, it provides a base-line cortisol measurement for the period before the relevant stressor occurs (Davenport et al., 2006).”
Hair cortisol concentrations were not impacted by collection region in cross-bred Angus steers
Loh, H. Y., Okoren, C., Marroquin, D. V., Keogh, L. M., Coetzee, J., Edwards-Callaway, L., Engle, T. E., & Cramer, C. (2025) · Frontiers in Animal Science · doi:10.3389/fanim.2025.1675995 · Cited by 2
Determining Cortisol in Animal Hair as a Marker of Chronic Stress
Samsonova, J., Saushkin, N., & Piskunov, A. (2025) · Biology Bulletin Reviews · doi:10.1134/s207908642560078x · Cited by 2
“…disturbance of wild chimpanzee habitat (Carlitz et al., 2016); intensive wolf hunting (Bryan et al., 2015); and the translocation of monkeys (Davenport et al., 2006; Fairbanks et al., 2011; Yamanashi et al., 2016a), rabbits (Peric et al., 2017, 2018), police horses (Gardela et al., 2020),…”
Development of an evidence-based welfare approach for cheetahs (Acinonyx jubatus) under human care
Fischer, B., Flint, M., Cole, K., & George, K. (2021) · Animal Welfare · doi:10.7120/09627286.30.3.006 · Cited by 2
A matter of habit? Stressful life events and cognitive flexibility in 15-month-olds
Tisborn, K., Kumsta, R., Zmyj, N., & Seehagen, S. (2023) · Infant Behavior and Development · doi:10.1016/j.infbeh.2023.101810 · Cited by 2
Associations of Household and Neighborhood Contexts and Hair Cortisol Among Mexican‐Origin Adolescents From Low‐Income Immigrant Families
Ip, K. I., Wen, W., Sim, L., Chen, S., & Kim, S. Y. (2024) · Developmental Psychobiology · doi:10.1002/dev.22519 · Cited by 2
“For the washing of hair and cortisol extraction, the protocol of Davenport et al. (2006) was employed.”
Method
Environmental determinants of chronic stress in fallow deer
Putman, R. J., Babayan, S. A., & Lesscher, H. M. B. (2024) · European Journal of Wildlife Research · doi:10.1007/s10344-024-01863-7 · Cited by 2
“Analysis of HCC then followed an adapted protocol from Davenport et al. (2006).”
Effects of Sericea Lespedeza Supplementation on Steers Grazing Wild-Type Endophyte-Infected Tall Fescue
Poudel, S., Pent, G. J., Fike, J. H., Zeller, W. E., & Davis, B. E. (2025) · Animals · doi:10.3390/ani15030373 · Cited by 2
Seasonal pattern of cortisol fluctuation in horsehair samples from three different body areas: A year long study
Skurková, L., Matulníková, L., Peťková, B., Florián, M., Slivková, M., Lešková, L., Mesarčová, L., & Kottferová, J. (2025) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2025.105387 · Cited by 2
Scales of our lives: Sex identification of Temminck’s pangolin (Smutsia temminckii) using scales retrieved out of the illegal wildlife trade
Blecher, A. S., Ganswindt, A., & Scheun, J. (2021) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2021.113782 · Cited by 2
How should the psychological welfare of zoo elephants be investigated
Mason, G. J., & Veasey, J. S. (2008) · The Atrium (University of Guelph) · Cited by 2
HAIR CORTISOL AS AN ANALYTICAL MEASURE OF CHRONIC STRESS
Paza, D. L. S., Pierozan, G. C., Furyama, G. Y., & Stefanello, J. M. F. (2017) · Psicologia Saúde & Doenças · doi:10.15309/17psd180312 · Cited by 2
Associations between hair and salivary cortisol, salivary alpha-amylase, and temperament dimensions among 3–6-year-olds
Sääksjärvi, K., Lehto, E., Lehto, R., Suhonen, E., Leppänen, M. H., Michels, N., Saha, M., Ray, C., Vepsäläinen, H., Pajulahti, R., et al. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2021.105042 · Cited by 2
“The laboratory washed the hair samples and extracted steroids according to the protocol of Davenport et al. (2006) HCC was measured from hair samples using a chemi-luminescence immunoassay (IBL, Hamburg, Germany).”
Biological Resources for Genomic Investigation in the Vervet Monkey (Chlorocebus)
Jasinska, A. J. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.002 · Cited by 3
Early Rearing Experience, Hypothalamic-Pituitary-Adrenal (HPA) Activity, and Serotonin Transporter Genotype: Influences on the Development of Anxiety in Infant Rhesus Monkeys (Macaca mulatta)
Dettmer, A. M. (2019) · Scholarworks (University of Massachusetts Amherst) · doi:10.7275/1030181 · Cited by 2
Unique Lemur Traits: Proximate and Ultimate Perspectives
Tennenhouse, E. M. (2016) · TSpace (University of Toronto) · Cited by 2
Child biological stress and maternal caregiving style are associated with school readiness
Ewell, A., Lopera‐Perez, D. C., Kao, K., Tuladhar, C. T., Meyer, J. S., & Tarullo, A. R. (2023) · Early Childhood Research Quarterly · doi:10.1016/j.ecresq.2023.11.003 · Cited by 1
Examining parental stress and its link to hair cortisol and DHEA levels in kindergartners
Rapp, L., & Pollatos, O. (2024) · Psychology and Health · doi:10.1080/08870446.2024.2347659 · Cited by 1
“The protocol developed by Kirschbaum et al. (2009) based on Davenport et al. (2006) was employed for hair washing and steroid extraction using an immunoassay with chemiluminescence detection (CLIA, IBL-Hamburg, Germany).”
Assessing chronic stress in sheep using wool cortisol: A comparative study of transhumant and intensive systems
Yetişgin, S. O., Şen, U., Önder, H., Yücel, C., Akça, B., Yüksel, H. M., & Yılmaz, Ö. F. (2025) · Small Ruminant Research · doi:10.1016/j.smallrumres.2025.107617 · Cited by 1
Coat color and other factors influencing hair cortisol concentration in domestic cats
Nutter, K. L., & Cooke, A. S. (2025) · Journal of Veterinary Diagnostic Investigation · doi:10.1177/10406387251384320 · Cited by 1
“9 The incorporation of cortisol in hair and the time hair takes to grow make hair cortisol a potentially valuable biomarker of long-term stress.”
Fit-for-purpose validation of hair cortisol concentration as a biomarker of dairy cow welfare
Botia, M., Contreras-Aguilar, M. D., Cerón, J. M. C., Llonch, P., Berteselli, G. V., Canali, E., Frondelius, L., & Stygar, A. H. (2025) · Journal of Dairy Research · doi:10.1017/s0022029925101039 · Cited by 1
“Hair cortisol extraction was performed according to the protocol of Davenport et al. (2006) modified by López-Arjona et al. (2020a).”
Sex Differences in Reaction to Chronic Unpredictable Stress in the House Mouse (Mus musculus musculus) of Wild Origin
Laktionova, T. K., Klyuchnikova, M. A., Kvasha, I. G., Laktionova, O., & Voznessenskaya, V. V. (2025) · Biology · doi:10.3390/biology15010054 · Cited by 1
“Hair corticosterone extraction and analysis were performed according to previously described protocols, with minor modifications [52,53].”
Chronic adrenocortical activity and onset of Takotsubo syndrome
Salmoirago‐Blotcher, E., Keirns, N. G., Ouaddi, S., Tripolone, J., Liu, C., Breault, C., & Dettmer, A. M. (2026) · European Journal of Cardiovascular Nursing · doi:10.1093/eurjcn/zvag023 · Cited by 1
Cortisol as a Stress Indicator of Environmental Change in Captive Cynomolgus Macaques (Macaca fascicularis)
Suriya-Arunroj, L., Huntula, T., Chimngam, M., Suttisan, N., Kongsombat, N., & Suwannachat, P. (2026) · International Journal of Primatology · doi:10.1007/s10764-026-00557-y · Cited by 1
“…system, and expressed fecal cortisol concentration as cortisol per unit fecal mass. Hair: We placed hair samples in 15-mL centrifuge tubes, added 10 mL of iso-propanol, and mixed tubes by repeated inversion on a rotator at room temperature for 3 min (Davenport et al. , 2006; Meyer et al. , 2014).”
Influential
Association of Maternal Hair Cortisol Level with Neonatal Facial Pain Expression Based on Newborns’ Gender
Aryaie, M., Hosseini, S. M., Sabzi, Z., Rafeeinia, A., Teymoori, H., & Dadashi, N. (2017) · Journal of Clinical and Basic Research · doi:10.29252/jcbr.1.4.41 · Cited by 1
Life History of Savanna Monkeys
Turner, T. R., Schmitt, C. A., & Cramer, J. D. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.014 · Cited by 1
Exploring the Biopsychosocial Model in Irritable Bowel Syndrome : with emphasis on stress, comorbidities and fatigue
Norlin, A. (2020) · Linköping University medical dissertations · doi:10.3384/diss.diva-170320 · Cited by 1
Validation and effects of drying and prey hair on fecal hormone concentrations in spotted hyenas
Greenberg, J. R., Montgomery, T. M., Holekamp, K. E., & Beehner, J. C. (2021) · Journal of Mammalogy · doi:10.1093/jmammal/gyab168 · Cited by 1
Non-Invasive Techniques Reveal Heifer Response to Fescue Endophyte Type in Grazing Studies
Poudel, S., Fike, J. H., Wright, L. L., & Pent, G. J. (2023) · Animals · doi:10.3390/ani13142373 · Cited by 1
“Previous studies have demonstrated a positive association between hair cortisol levels and stressors such as heat stress, handling, and transport [53,57].”
Background
Quality of hematology and clinical chemistry results in laboratory and zoo nonhuman primates: Effects of the preanalytical phase. A review
Granat, F., Trumel, C., Braun, J., & Bourgès-Abella, N. (2023) · Journal of medical primatology · doi:10.1111/jmp.12666 · Cited by 1
“197 Hair cortisol was lower in subjects more involved in social behaviors, as shown in semi-free ranging rhesus macaques, 205,206 in capuchin monkeys central to an affilia-tive network, 207 and in infant rhesus macaques reared with their mothers compared to those reared in nurseries 204 ; it was…”
Background
Clippers are superior to scissors in the collection of hair for chemical analysis in companion dogs: a Dog Aging Project preliminary study
Ditzler, B., Evans, J. B., Illing, K., Kaeberlein, M. R., Promislow, D., Brindle, E., Hoffman, J. M., & Creevy, K. E. (2024) · American Journal of Veterinary Research · doi:10.2460/ajvr.23.12.0293 · Cited by 1
Toward the validation of an alternative method for endocrine monitoring in sharks: insights from testosterone analyses in the skin of bycatch individuals
Carbajal, A., HUA‐MONCLÚS, J., Serres‐Corral, P., Lobato, I. G., Muñoz-Baquero, M., & López‐Béjar, M. (2024) · Integrative Zoology · doi:10.1111/1749-4877.12873 · Cited by 1
Non-invasive wool hormone assessment of Australian merino rams (Ovis aries): a pilot investigation of cortisol and testosterone
Fox, D., Wilson, B., & Narayan, E. (2024) · Frontiers in Veterinary Science · doi:10.3389/fvets.2024.1448232 · Cited by 1
“Steroids incorporated in the hair/wool shaft are not affected by the daily fluctuations of the hormones and can store the steroid changes for weeks or even months, depending on the species (4, 15–19).”
BackgroundInfluential
Ethnoprimatology and Savanna Monkeys
Turner, T. R., Schmitt, C. A., & Cramer, J. D. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.019 · Cited by 1
Interactions between the Hypothalamic-Pituitary-Adrenal (HPA) Axis, Oxytocin System, and Behavior in Differently Reared Rhesus Monkeys (Macaca mulatta)
Hamel, A. F. (2021) · ScholarWorks@UMassAmherst (University of Massachusetts Amherst) · doi:10.7275/6948874.0 · Cited by 1
Behavior and socioendocrinology of adult male rhesus macaques of Cayo Santiago
Rakhovskaya, M. (2011) · ScholarlyCommons (University of Pennsylvania) · Cited by 1
Avaliação das concentrações de testosterona no pêlo de cães domésticos (Canis lupus familiaris)
Guerreiro, C. V. C. (2008) · doi:10.11606/t.10.2008.tde-27112008-141029 · Cited by 1
“…do pêlo não seja na mesma velocidade que outras matrizes biológicas como sangue e urina, sua análise proporciona valioso complemento e método prático para determinação de eventos ocorridos no passado ( BAUMGARTNER et al., 1979) como monitoramento do estresse crônico (DAVENPORT et al., 2006).”
BackgroundInfluential
Indirect Effects of Predation in Human-Modified Landscapes.
Sahlén, E. (2016) · Epsilon Open Archive (Sveriges lantbruksuniversitet biblioteket (Swedish University of Agricultural Sciences)) · Cited by 1
Rejection in early life is associated with high and long-lasting stress and higher incidence of infections in owl monkeysPreprint
Osman, M., Olkun, A., Maldonado, A. M., Tremoleda, J. L., Sanchez‐Perea, N., & Paredes, U. M. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.17.343921 · Cited by 1
HPA Axis
Meyer, J. S., & Novak, M. A. (2017) · The International Encyclopedia of Primatology · doi:10.1002/9781119179313.wbprim0142 · Cited by 1
Longitudinal hair cortisol in bipolar disorder and a mechanism based on HPA dynamicsPreprint
Alon, U., Milo, T., Maimon, L., Cohen, B., Haran, D., Segman, D., Danon, T., Bren, A., Mayo, A., Rappaport, G. C., et al. (2023) · Research Square · doi:10.21203/rs.3.rs-3090576/v1 · Cited by 1
Human Hair from the Wreck of Hms Erebus of the Franklin Expedition, 1845: Elemental Chemistry Revealed by Double-Ablation La-Icp-MsPreprint
BOWMAN, A. W., Christensen, J. R., Dagneau, C., Kavousanaki, D., Millar, K., & Moore, J. (2023) · SSRN Electronic Journal · doi:10.2139/ssrn.4522893 · Cited by 1
Old world monkeys
Bakker, J., Louwerse, A. L., Vernes, M. K., & Langermans, J. A. M. (2024) · Wiley eBooks · doi:10.1002/9781119555278.ch39 · Cited by 1
Non-invasive hormone assessment of Australian Merino Rams ( Ovis aries ): A pilot investigation of cortisol, testosterone and heat stressPreprint
Fox, D., Wilson, B., & Narayan, E. J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.12.598752 · Cited by 1
Parasites and Hormones as Non-invasive Bioindicators of Ecophysiology in Carnivores
Bryan, H. M. (2013) · Libraries and Cultural Resources (University of Calgary) · doi:10.5072/prism/27255 · Cited by 1
Hair Cortisol Concentrations in High- and Low-Stress Mother-Daughter Dyads
Ouellette, S. J. (2015) · Scholarship@Western (Western University)
Variability of Hormonal Stress Markers and Stress Responses in a Large Cross-Sectional Sample of Elephant Seals
Crocker, D. E., Houser, D. S., Janz, D. M., Kellar, N., & Cockrem, J. F. (2012) · doi:10.21236/ada573471
RELATIONSHIP BETWEEN GENETIC MERIT AND BIOLOGICAL RESPONSE IN LACTATING COWS
Fanzago, M. (2015) · Institutional Research Information System (University of Udine)
VALIDATION OF A NEW METHOD TO ASSESS THE LONG-TERM HYPOTHALAMIC-PITUITARY-ADRENAL ACTIVITY USING HAIR GLUCOCORTICOIDS AS BIOMARKERS.
Veterinarie, S. (2014)
RESEARCH ARTICLE Effectiveness of Saliva Collection and Enzyme-Immunoassay for the Quantification of Cortisol in Socially Housed Baboons
Pearson, B. L., Judge, P. G., & Reeder, D. M. (2008)
Individual differences in adrenal axis activity and stress sensitivity in female cynomolgus monkeys (Macaca fascicularis).
Herod, S. M. (2009) · doi:10.6083/m42805kw
Retrospektive Erfassung der kumulativen Cortisolsekretion mittels Haarsegmentanalyse bei traumaexponierten Kindern und Jugendlichen
Ulm, U., Direktor, Ä., & Fegert, J. M. (2012)
The Influence of Surgical Stress on Human Scalp Hair Fiber Dimensions
Scott, A. (2015) · Summit (Simon Fraser University)
EFFECTS OF STRESS ON ONSET OF MIDDLE CHILDHOOD AMONG SIDAMA AGROPASTORALISTS
Helfrecht, C. (2016) · Research Exchange (Washington State University)
Chronic stress in deer
de Rooij, A. (2016) · Utrecht University Repository (Utrecht University)
An Investigation of Hair Cortisol as a Biomarker of Long-Term Stress in Beef Cattle
Creutzinger, K. C. (2016) · University Library - University of Saskatchewan (University of Saskatchewan)
A Preliminary Assessment of Steroid Reproductive Hormones in Archaeological Human Hair Utilizing a Modified Enzyme-Linked Immunosorbent Assay (ELISA) Technique
Tisdale, E. W. (2017) · Journal of International Crisis and Risk Communication Research
Sistemas de baias coletivas sem e com acesso a piquete externo: bem-estar e desempenho zootécnico de matrizes suínas e leitões na fase reprodutiva
Farias, S. D. S. (2017) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.74.2017.tde-31072017-105329
The Vervet Microbiome
Amato, K. R. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.006
Measurement of Novelty-Seeking in Wild Vervet Monkeys
Blaszczyk, M. B. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.017
Population Genetic Structure of Vervet Monkeys in South Africa
Coetzer, W. G., Lorenz, J. G., Freimer, N. B., & Grobler, J. P. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.008
Exploring Caribbean Green Monkeys (Chlorocebus sabaeus) through an Ethnoprimatological Lens
Dore, K. M. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.020
Causes of Variation in the Static Allometry of Morphological Structures: A Case Study with Vervet Monkeys
Rodrı́guez, R. L., Gaetano, T. J., Grobler, J. P., & Freimer, N. B. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.018
The Promise of Vervet Genomics
Warren, W. C., & Montague, M. J. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.004
African Green Monkeys as a Natural Host of SIV
Apetrei, C., Raehtz, K. D., & Pandrea, I. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.005
Socioecology of Vervet Monkeys
Whitten, P. L. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.010
Predation and Food Competition in Vervet Monkeys (Chlorocebus pygerythrus)
Isbell, L. A. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.012
Vervet Monkeys (Chlorocebus pygerthrus), Chimpanzees (Pan troglodytes), and Humans (Homo sapiens): Studying Interactions Using Stable Isotope Analysis
Sponheimer, M., Loudon, J. E., Grobler, J. P., Moyer, K., & Lorenz, J. G. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.021
Population Genetics and Savanna Monkeys
Turner, T. R., Schmitt, C. A., & Cramer, J. D. (2019) · Cambridge University Press eBooks · doi:10.1017/9781139019941.007

Authors: Davenport, M. D., Tiefenbacher, S., Lutz, C. K., Novak, M. A., & Meyer, J. S.
Affiliations: Harvard University (US)
University of Massachusetts Amherst (US)
Corresponding author: Meyer, Jerrold S.
ORCID: Lutz, Corrine K.
Novak, Melinda A.
Meyer, Jerrold S.
Venue: General and Comparative Endocrinology
Publisher: Elsevier BV
Published: 2006-07
Volume: 147
Issue: 3
Pages: 255-261
ISSN: 0016-6480 (ISSN-L)
DOI: 10.1016/j.ygcen.2006.01.005
OpenAlex: W2074364102
Cited by: 659
References: 31
Citations by year: 2026: 18 · 2025: 29 · 2024: 33 · 2023: 41 · 2022: 35 · 2021: 53 · 2020: 44 · 2019: 73 · 2018: 33 · 2017: 52 · 2016: 53 · 2015: 35 · 2014: 31 · 2013: 28 · 2012: 30
FWCI: 3.82
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: General and Comparative Endocrinology (publishedVersion)
PubMed (publishedVersion)
Funders: National Center for Research Resources (#RR11122, RR00 168, R24RR011122)
Topics: Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Life Sciences › Agricultural and Biological Sciences › Animal Science and Zoology › Animal Behavior and Welfare Studies
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adrenal Hormones and Disorders
Keywords: hair cortisol, rhesus monkeys, hypothalamic-pituitary-adrenal axis, chronic stress, non-human primates, stress biomarkers, enzyme immunoassay validation
MeSH terms: Animals, Hair, Hydrocortisone, Immunoenzyme Techniques, Macaca mulatta, Male, Saliva, Sensitivity and Specificity, Skin, Stress, Physiological, Time Factors

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Analysis of endogenous cortisol concentrations in the hair of rhesus macaques

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks