Pregnancy-induced changes in ultradian rhythms persist in circadian arrhythmic Siberian hamsters
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The impact of pregnancy and lactation on ultradian rhythms (URs) and circadian rhythms (CRs) of locomotor activity was assessed in circadian rhythmic and arrhythmic Siberian hamsters maintained in a long-day photoperiod (16h light/day). Progressive decrements in CR robustness and amplitude over the course of gestation were accompanied by enhanced URs. Dark-phase UR period and amplitude increased during early gestation and complexity and robustness increased during late gestation. The persistence of pregnancy-associated enhancements of URs in circadian arrhythmic (ARR) hamsters suggests that reproductive modulation of the UR waveform is not dependent on coherent circadian organization. The increased incidence of dark-phase URs appeared more rapidly in ARR dams than entrained (ENTR) dams. Throughout gestation, the percentage of dams with dark-phase URs was significantly greater in the ARR group. Gestational increases in UR complexity and robustness emerged earlier and were greater in ARR than ENTR dams. The attenuation of CRs during lactation is correlated with increased expression of URs. Relaxation of circadian control of the dam's behavior may increase fitness by permitting more efficient interactions with circadian arrhythmic pups.
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Several physiological systems exhibit ultradian rhythms in the 1-3 h range, including the HPG axis, HPA axis, and suprachiasmatic nucleus.
“Several physiological systems exhibit ultradian rhythms (URs) in the 1–3 h range, including the HPG axis60–65, the HPA axis66–72, and the suprachiasmatic nucleus73, 74 – the principal orchestrating brain area for circadian rhythms.”
From Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice (2017) · cites this paper as [65]
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- Authors
- Wang, Z. Y., Cable, E. J., Zucker, I., & Prendergast, B. J.
- Affiliations
- University of Chicago (US)
- University of California, Berkeley (US)
- Corresponding author
- Wang, Z. Yan
- Venue
- Hormones and Behavior
- Publisher
- Elsevier BV
- Published
- 2014-07
- Volume
- 66
- Issue
- 2
- Pages
- 228-237
- ISSN
- 0018-506X (ISSN-L)
- PMC
- PMC4372156
- OpenAlex
- W2054015996
- Cited by
- 7
- References
- 55
- Citations by year
- 2026: 1 · 2022: 2 · 2021: 1 · 2017: 2 · 2016: 1
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Hormones and Behavior (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- Missouri State University RStats Institute
- Institute for Mind and Biology at the University of Chicago
- National Science Foundation (DGE-0903637)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Keywords
- pregnancy, ultradian rhythms, circadian rhythm, locomotor activity, Siberian hamster, gestation, lactation, long-day photoperiod, circadian entrainment, maternal behavior
- MeSH terms
- Activity Cycles, Animals, Circadian Rhythm, Darkness, Female, Cricetinae, Light, Motor Activity, Phenotype, Pregnancy, Sexual Behavior, Animal, Phodopus
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