Effect of reproductive state on circadian periodicity in the rat
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In adult laboratory rodents, a wide variety of gonadal hormones can affect the phase of circadian rhythms.
“Indeed, in adult laboratory rodents a wide variety of gonadal hormones can affect the phase of circadian rhythms, including estrogens, progestins, androgens, and non-traditional neuroactive steroids (e.g., rats: [8, 17], hamsters: [49, 51, 129], mice: [23, 47, 78, 90], degus: [80, 100]).”
From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [8]
Gonadal hormones can influence other circadian parameters including endogenous period, rhythm amplitude, range of entrainment, zeitgeber sensitivity, and oscillator coupling.
“Gonadal hormones can influence other circadian parameters as well, including endogenous period [7, 23, 47, 49, 91, 129, 212], rhythm amplitude [8, 17, 100], range of entrainment [49], zeitgeber sensitivity [23, 51, 79, 81], and oscillator coupling [126, 128, 187].”
From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [8]
The shift in chronotype that occurs during puberty in male rats may be similar to the shift in the rest/activity rhythm that occurs due to high estrogen during the estrus cycle in adult females.
“Thus, the shift in chronotype that occurs during puberty in male rats may be similar to the shift in the rest/activity rhythm that occurs due to high estrogen during the estrus cycle in adult females [8, 17].”
From The neuroendocrine control of the circadian system: Adolescent chronotype (2012) · cites this paper as [8]
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- Authors
- Albers, E. E., Gerall, A. A., & Axelson, J. F.
- Affiliations
- Tulane University (US)
- Venue
- Physiology & Behavior
- Publisher
- Elsevier BV
- Published
- 1981-01
- Volume
- 26
- Issue
- 1
- Pages
- 21-25
- ISSN
- 0031-9384 (ISSN-L)
- OpenAlex
- W2025216323
- Cited by
- 147
- References
- 15
- Citations by year
- 2026: 2 · 2025: 4 · 2024: 5 · 2023: 4 · 2022: 8 · 2021: 8 · 2020: 4 · 2019: 3 · 2018: 1 · 2017: 1 · 2016: 3 · 2015: 2 · 2014: 2 · 2013: 4 · 2012: 4
- FWCI
- 1.33
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physiology & Behavior (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Estrogen and related hormone effects
- Keywords
- circadian rhythm, estrous cycle, reproductive status, pseudopregnancy, locomotor activity, phase difference, free-running period, activity time, light-dark cycle, estrogen, female rats
- MeSH terms
- Animals, Circadian Rhythm, Estradiol, Estrus, Female, Motor Activity, Pregnancy, Pseudopregnancy, Time Factors, Rats
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