CoChat
Sign Up
Cited by 273

The DOI matches its Crossref record; 15 of the 15 references it cites were found in a registry or an index.

In Vivo Excision of HIV-1 Provirus by saCas9 and Multiplex Single-Guide RNAs in Animal Models

Yin, Chaoran, Zhang, Ting, Qu, Xiying, Zhang, Yonggang, Putatunda, Raj, Xiao, Xiao, Li, Fang, Xiao, Weidong, Zhao, Huaqing, Dai, Shen, Qin, Xuebin, Mo, Xianming, Young, Won-Bin, Khalili, Kamel, Hu, Wenhui·2017·Molecular Therapy
DOI 10.1016/j.ymthe.2017.03.012
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.ymthe.2017.03.012

Cites

15 of 15 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Show all 15 references

Research works printed but not linked: 70

  1. Hastie, 2015, Adeno-associated virus at 50: a golden anniversary of discovery, research, and gene therapy success--a personal perspective, Hum. Gene Ther., 26, 257, 10.1089/hum.2015.025 · DOI
  2. Zuris, 2015, Cationic lipid-mediated delivery of proteins enables efficient protein-based genome editing in vitro and in vivo, Nat. Biotechnol., 33, 73, 10.1038/nbt.3081 · DOI · Paper page
  3. Yin, 2014, Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype, Nat. Biotechnol., 32, 551, 10.1038/nbt.2884 · DOI · Paper page
  4. Manjunath, 2013, Newer gene editing technologies toward HIV gene therapy, Viruses, 5, 2748, 10.3390/v5112748 · DOI · Paper page
  5. Wang, 2014, CCR5 gene disruption via lentiviral vectors expressing Cas9 and single guided RNA renders cells resistant to HIV-1 infection, PLoS ONE, 9, e115987, 10.1371/journal.pone.0115987 · DOI
  6. Hu, 2014, RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection, Proc. Natl. Acad. Sci. USA, 111, 11461, 10.1073/pnas.1405186111 · DOI · Paper page
  7. Liao, 2015, Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells, Nat. Commun., 6, 6413, 10.1038/ncomms7413 · DOI
  8. Zhu, 2015, The CRISPR/Cas9 system inactivates latent HIV-1 proviral DNA, Retrovirology, 12, 22, 10.1186/s12977-015-0150-z · DOI
  9. Kaminski, 2016, Elimination of HIV-1 genomes from human T-lymphoid cells by CRISPR/Cas9 gene editing, Sci. Rep., 6, 22555, 10.1038/srep22555 · DOI
  10. Yin, 2016, Functional screening of guide RNAs targeting the regulatory and structural HIV-1 viral genome for a cure of AIDS, AIDS, 30, 1163, 10.1097/QAD.0000000000001079 · DOI
  11. Kaminski, 2016, Excision of HIV-1 DNA by gene editing: a proof-of-concept in vivo study, Gene Ther., 23, 690, 10.1038/gt.2016.41 · DOI
  12. Rabinovich, 2008, Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer, Proc. Natl. Acad. Sci. USA, 105, 14342, 10.1073/pnas.0804105105 · DOI
  13. Potash, 2005, A mouse model for study of systemic HIV-1 infection, antiviral immune responses, and neuroinvasiveness, Proc. Natl. Acad. Sci. USA, 102, 3760, 10.1073/pnas.0500649102 · DOI
  14. Khalili, 2015, Genome editing strategies: potential tools for eradicating HIV-1/AIDS, J. Neurovirol., 21, 310, 10.1007/s13365-014-0308-9 · DOI
  15. Nishimasu, 2015, Crystal structure of Staphylococcus aureus Cas9, Cell, 162, 1113, 10.1016/j.cell.2015.08.007 · DOI
  16. Friedland, 2015, Characterization of Staphylococcus aureus Cas9: a smaller Cas9 for all-in-one adeno-associated virus delivery and paired nickase applications, Genome Biol., 16, 257, 10.1186/s13059-015-0817-8 · DOI
  17. Allocca, 2008, Serotype-dependent packaging of large genes in adeno-associated viral vectors results in effective gene delivery in mice, J. Clin. Invest., 118, 1955, 10.1172/JCI34316 · DOI · Paper page
  18. Wu, 2007, Self-complementary recombinant adeno-associated viral vectors: packaging capacity and the role of rep proteins in vector purity, Hum. Gene Ther., 18, 171, 10.1089/hum.2006.088 · DOI · Paper page
  19. Bartel, 2011, Enhancing the clinical potential of AAV vectors by capsid engineering to evade pre-existing immunity, Front. Microbiol., 2, 204, 10.3389/fmicb.2011.00204 · DOI · Paper page
  20. Dickie, 1991, HIV-associated nephropathy in transgenic mice expressing HIV-1 genes, Virology, 185, 109, 10.1016/0042-6822(91)90759-5 · DOI
  21. Kopp, 1992, Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes, Proc. Natl. Acad. Sci. USA, 89, 1577, 10.1073/pnas.89.5.1577 · DOI
  22. Haque, 2016, HIV promotes NLRP3 inflammasome complex activation in murine HIV-associated nephropathy, Am. J. Pathol., 186, 347, 10.1016/j.ajpath.2015.10.002 · DOI
  23. Cheung, 2015, Cardiac dysfunction in HIV-1 transgenic mouse: role of stress and BAG3, Clin. Transl. Sci., 8, 305, 10.1111/cts.12331 · DOI
  24. Hahn, 2012, HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: coordinated response to opiates during maturation, Glia, 60, 1871, 10.1002/glia.22403 · DOI
  25. Das, 2011, Viral infection and neural stem/progenitor cell’s fate: implications in brain development and neurological disorders, Neurochem. Int., 59, 357, 10.1016/j.neuint.2011.02.020 · DOI
  26. Mishra, 2010, Human immunodeficiency virus type 1 Tat modulates proliferation and differentiation of human neural precursor cells: implication in NeuroAIDS, J. Neurovirol., 16, 355, 10.3109/13550284.2010.513028 · DOI
  27. Rothenaigner, 2007, Long-term HIV-1 infection of neural progenitor populations, AIDS, 21, 2271, 10.1097/QAD.0b013e3282f12f27 · DOI
  28. Schwartz, 2007, Evidence of human immunodeficiency virus type 1 infection of nestin-positive neural progenitors in archival pediatric brain tissue, J. Neurovirol., 13, 274, 10.1080/13550280701344975 · DOI
  29. Fatima, 2016, Tripartite containing motif 32 modulates proliferation of human neural precursor cells in HIV-1 neurodegeneration, Cell Death Differ., 23, 776, 10.1038/cdd.2015.138 · DOI
  30. Schneider, 2015, A new model for post-integration latency in macroglial cells to study HIV-1 reservoirs of the brain, AIDS, 29, 1147, 10.1097/QAD.0000000000000691 · DOI
  31. Balinang, 2017, Productive infection of human neural progenitor cells by R5 tropic HIV-1: opiate co-exposure heightens infectivity and functional vulnerability, AIDS, 31, 753, 10.1097/QAD.0000000000001398 · DOI
  32. Mao, 2016, Single point mutation in adeno-associated viral vectors -DJ capsid leads to improvement for gene delivery in vivo, BMC Biotechnol., 16, 1, 10.1186/s12896-015-0230-0 · DOI
  33. Holehonnur, 2014, Adeno-associated viral serotypes produce differing titers and differentially transduce neurons within the rat basal and lateral amygdala, BMC Neurosci., 15, 28, 10.1186/1471-2202-15-28 · DOI
  34. Zhang, 2015, CRISPR/gRNA-directed synergistic activation mediator (SAM) induces specific, persistent and robust reactivation of the HIV-1 latent reservoirs, Sci. Rep., 5, 16277, 10.1038/srep16277 · DOI
  35. Kelschenbach, 2012, Mice chronically infected with chimeric HIV resist peripheral and brain superinfection: a model of protective immunity to HIV. J, Neuroimmune Pharmacol, 7, 380, 10.1007/s11481-011-9316-1 · DOI
  36. Song, 2015, Visualization and quantification of simian immunodeficiency virus-infected cells using non-invasive molecular imaging, J. Gen. Virol., 96, 3131, 10.1099/jgv.0.000245 · DOI
  37. Fuchs, 2016, Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies, Mol. Ther. Methods Clin. Dev., 3, 16068, 10.1038/mtm.2016.68 · DOI
  38. Brady, 2017, Antibody gene transfer with adeno-associated viral vectors as a method for HIV prevention, Immunol. Rev., 275, 324, 10.1111/imr.12478 · DOI
  39. Wang, 2016, CRISPR/Cas9-derived mutations both inhibit HIV-1 replication and accelerate viral escape, Cell Rep., 15, 481, 10.1016/j.celrep.2016.03.042 · DOI
  40. Wang, 2016, CRISPR-Cas9 can inhibit HIV-1 replication but NHEJ repair facilitates virus escape, Mol. Ther., 24, 522, 10.1038/mt.2016.24 · DOI
  41. Bauer, 2015, Generation of genomic deletions in mammalian cell lines via CRISPR/Cas9, J. Vis. Exp., 95, e52118
  42. Peng, 2015, High-throughput screens in mammalian cells using the CRISPR-Cas9 system, FEBS J., 282, 2089, 10.1111/febs.13251 · DOI
  43. Kabadi, 2014, Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector, Nucleic Acids Res., 42, e147, 10.1093/nar/gku749 · DOI · Paper page
  44. Rothe, 2014, Safety of gene therapy: new insights to a puzzling case, Curr. Gene Ther., 14, 429, 10.2174/1566523214666140918110905 · DOI
  45. Mingozzi, 2013, Immune responses to AAV vectors: overcoming barriers to successful gene therapy, Blood, 122, 23, 10.1182/blood-2013-01-306647 · DOI · Paper page
  46. Moser, 2016, AAV vectorization of DSB-mediated gene editing technologies, Curr. Gene Ther., 16, 207, 10.2174/1566523216666160602213738 · DOI
  47. Platt, 2014, CRISPR-Cas9 knockin mice for genome editing and cancer modeling, Cell, 159, 440, 10.1016/j.cell.2014.09.014 · DOI · Paper page
  48. Senís, 2014, CRISPR/Cas9-mediated genome engineering: an adeno-associated viral (AAV) vector toolbox, Biotechnol. J., 9, 1402, 10.1002/biot.201400046 · DOI
  49. Howes, 2015, Genome engineering using adeno-associated virus (AAV), Methods Mol. Biol., 1239, 75, 10.1007/978-1-4939-1862-1_5 · DOI
  50. Hung, 2016, AAV-mediated CRISPR/Cas gene editing of retinal cells in vivo, Invest. Ophthalmol. Vis. Sci., 57, 3470, 10.1167/iovs.16-19316 · DOI · Paper page
  51. Wright, 2015, Rational design of a split-Cas9 enzyme complex, Proc. Natl. Acad. Sci. USA, 112, 2984, 10.1073/pnas.1501698112 · DOI
  52. Zetsche, 2015, A split-Cas9 architecture for inducible genome editing and transcription modulation, Nat. Biotechnol., 33, 139, 10.1038/nbt.3149 · DOI
  53. Nguyen, 2016, Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity, Nat. Commun., 7, 12009, 10.1038/ncomms12009 · DOI
  54. Nuñez, 2016, Chemical and biophysical modulation of Cas9 for tunable genome engineering, ACS Chem. Biol., 11, 681, 10.1021/acschembio.5b01019 · DOI
  55. Fine, 2015, Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes, Sci. Rep., 5, 10777, 10.1038/srep10777 · DOI
  56. Nissim, 2014, Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells, Mol. Cell, 54, 698, 10.1016/j.molcel.2014.04.022 · DOI
  57. Gao, 2014, Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing, J. Integr. Plant Biol., 56, 343, 10.1111/jipb.12152 · DOI
  58. Sakuma, 2014, Multiplex genome engineering in human cells using all-in-one CRISPR/Cas9 vector system, Sci. Rep., 4, 5400, 10.1038/srep05400 · DOI · Paper page
  59. Denton, 2012, Generation of HIV latency in humanized BLT mice, J. Virol., 86, 630, 10.1128/JVI.06120-11 · DOI
  60. Wang, 2016, Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles, Proc. Natl. Acad. Sci. USA, 113, 2868, 10.1073/pnas.1520244113 · DOI · Paper page
  61. Sun, 2015, Self-assembled DNA nanoclews for the efficient delivery of CRISPR-Cas9 for genome editing, Angew. Chem. Int. Ed. Engl., 54, 12029, 10.1002/anie.201506030 · DOI · Paper page
  62. Hu, 2015, Generation of a stable packaging cell line producing high-titer PPT-deleted integration-deficient lentiviral vectors, Mol. Ther. Methods Clin. Dev., 2, 15025, 10.1038/mtm.2015.25 · DOI
  63. Yu, 2016, Improved delivery of Cas9 protein/gRNA complexes using lipofectamine CRISPRMAX, Biotechnol. Lett., 38, 919, 10.1007/s10529-016-2064-9 · DOI
  64. Tycko, 2016, Methods for optimizing CRISPR-Cas9 genome editing specificity, Mol. Cell, 63, 355, 10.1016/j.molcel.2016.07.004 · DOI
  65. Kleinstiver, 2015, Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition, Nat. Biotechnol., 33, 1293, 10.1038/nbt.3404 · DOI · Paper page
  66. Kim, 2015, Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells, Nat. Methods, 12, 237, 10.1038/nmeth.3284 · DOI · Paper page
  67. Zuckermann, 2015, Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling, Nat. Commun., 6, 7391, 10.1038/ncomms8391 · DOI · Paper page
  68. Yang, 2014, Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells, Nat. Commun., 5, 5507, 10.1038/ncomms6507 · DOI
  69. Zolotukhin, 1999, Recombinant adeno-associated virus purification using novel methods improves infectious titer and yield, Gene Ther., 6, 973, 10.1038/sj.gt.3300938 · DOI
  70. al Yacoub, 2007, Optimized production and concentration of lentiviral vectors containing large inserts, J. Gene Med., 9, 579, 10.1002/jgm.1052 · DOI

Cited by

Sorted by citations

See all 273

Metadata

Authors
Yin, C., Zhang, T., Qu, X., Zhang, Y., Putatunda, R., Xiao, X., Li, F., Xiao, W., Zhao, H., Dai, S., Qin, X., Mo, X., Young, W.-B., Khalili, K., & Hu, W.
Venue
Molecular Therapy
Publisher
Elsevier BV
Published
2017-05
Volume
25
Issue
5
Pages
1168-1186
ISSN
1525-0016
DOI
10.1016/j.ymthe.2017.03.012
Cited by
273
References
15
Language
en
Licence
Funders
NIH (R01NS087971, P30MH092177, R21MH100949, R21NS094084, 5T32MH079785)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review