Cited by 370

The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

Kabadi, Ami M., Ousterout, David G., Hilton, Isaac B., Gersbach, Charles A.·2014·Nucleic Acids Research

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1093/nar/gku749

Cites

14 of 14 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Non-viral methods lack the potential to deliver CRISPR/Cas9 in clinical settings in the near future due to difficulties in yielding proper ratio for gene editing and lack of transduction efficacy.

    “However, due to difficulties in yielding proper ratio for gene editing and the lack of transduction efficacy, these methods lack the potential to deliver CRISPR/Cas9 in clinical settings in the near future [65].”

    From Viral Delivery Systems for CRISPR (2019) · cites this paper as [65]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Flagged first, then by citations

Research works printed but not linked: 47

  1. Gaj, 2013, ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering, Trends Biotechnol., 31, 397, 10.1016/j.tibtech.2013.04.004 · DOI · Paper page
  2. Perez-Pinera, 2012, Advances in targeted genome editing, Curr. Opin. Chem. Biol., 16, 268, 10.1016/j.cbpa.2012.06.007 · DOI
  3. Gersbach, 2014, Synthetic zinc finger proteins: the advent of targeted gene regulation and genome modification technologies, Acc. Chem. Res., 10.1021/ar500039w · DOI
  4. Urnov, 2005, Highly efficient endogenous human gene correction using designed zinc-finger nucleases, Nature, 435, 646, 10.1038/nature03556 · DOI
  5. Zou, 2011, Site-specific gene correction of a point mutation in human iPS cells derived from an adult patient with sickle cell disease, Blood, 118, 4599, 10.1182/blood-2011-02-335554 · DOI
  6. Sebastiano, 2011, In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases, Stem Cells, 29, 1717, 10.1002/stem.718 · DOI
  7. Osborn, 2013, TALEN-based gene correction for epidermolysis bullosa, Mol. Ther., 21, 1151, 10.1038/mt.2013.56 · DOI · Paper page
  8. Ousterout, 2013, Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients, Mol. Ther., 21, 1718, 10.1038/mt.2013.111 · DOI
  9. Tebas, 2014, Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV, N. Engl. J. Med., 370, 901, 10.1056/NEJMoa1300662 · DOI · Paper page
  10. Zhang, 2000, Synthetic zinc finger transcription factor action at an endogenous chromosomal site. Activation of the human erythropoietin gene, J. Biol. Chem., 275, 33850, 10.1074/jbc.M005341200 · DOI
  11. Liu, 2001, Regulation of an endogenous locus using a panel of designed zinc finger proteins targeted to accessible chromatin regions. Activation of vascular endothelial growth factor A, J. Biol. Chem., 276, 11323, 10.1074/jbc.M011172200 · DOI
  12. Maeder, 2013, CRISPR RNA-guided activation of endogenous human genes, Nat. Methods, 10, 977, 10.1038/nmeth.2598 · DOI · Paper page
  13. Maeder, 2013, Robust, synergistic regulation of human gene expression using TALE activators, Nat. Methods, 10, 243, 10.1038/nmeth.2366 · DOI
  14. Perez-Pinera, 2013, Synergistic and tunable human gene activation by combinations of synthetic transcription factors, Nat. Methods, 10, 239, 10.1038/nmeth.2361 · DOI
  15. Perez-Pinera, 2013, RNA-guided gene activation by CRISPR-Cas9-based transcription factors, Nat. Methods, 10, 973, 10.1038/nmeth.2600 · DOI · Paper page
  16. Gersbach, 2014, Activating human genes with zinc finger proteins, transcription activator-like effectors and CRISPR/Cas9 for gene therapy and regenerative medicine, Expert Opin. Ther. Targets, 18, 835, 10.1517/14728222.2014.913572 · DOI
  17. Kabadi, 2014, Engineering synthetic TALE and CRISPR/Cas9 transcription factors for regulating gene expression, Methods, 10.1016/j.ymeth.2014.06.014 · DOI
  18. Maeder, 2013, Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins, Nat. Biotechnol., 31, 1137, 10.1038/nbt.2726 · DOI
  19. Konermann, 2013, Optical control of mammalian endogenous transcription and epigenetic states, Nature, 500, 472, 10.1038/nature12466 · DOI · Paper page
  20. Siddique, 2013, Targeted methylation and gene silencing of VEGF-A in human cells by using a designed Dnmt3a-Dnmt3L single-chain fusion protein with increased DNA methylation activity, J. Mol. Biol., 425, 479, 10.1016/j.jmb.2012.11.038 · DOI
  21. Mendenhall, 2013, Locus-specific editing of histone modifications at endogenous enhancers, Nat. Biotechnol., 31, 1133, 10.1038/nbt.2701 · DOI
  22. Jinek, 2013, RNA-programmed genome editing in human cells, eLife, 2, e00471, 10.7554/eLife.00471 · DOI · Paper page
  23. Cho, 2013, Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease, Nat. Biotechnol., 31, 230, 10.1038/nbt.2507 · DOI · Paper page
  24. Cheng, 2013, Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system, Cell Res., 23, 1163, 10.1038/cr.2013.122 · DOI
  25. Farzadfard, 2013, Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas, ACS Synthet. Biol., 2, 604, 10.1021/sb400081r · DOI
  26. Kearns, 2014, Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells, Development, 141, 219, 10.1242/dev.103341 · DOI
  27. Ohshima, 1981, Nucleotide sequences of mouse genomic loci including a gene or pseudogene for U6 (4.8S) nuclear RNA, Nucleic Acids Res., 9, 5145, 10.1093/nar/9.19.5145 · DOI
  28. Myslinski, 2001, An unusually compact external promoter for RNA polymerase III transcription of the human H1RNA gene, Nucleic Acids Res., 29, 2502, 10.1093/nar/29.12.2502 · DOI
  29. Murphy, 1987, The in vitro transcription of the 7SK RNA gene by RNA polymerase III is dependent only on the presence of an upstream promoter, Cell, 51, 81, 10.1016/0092-8674(87)90012-2 · DOI
  30. Salmon, 2006, Production and titration of lentiviral vectors, Curr. Protoc. Neurosci., 4, 4.21.1, 10.1002/0471142301.ns0421s37 · DOI
  31. Guschin, 2010, A rapid and general assay for monitoring endogenous gene modification, Methods Mol. Biol., 649, 247, 10.1007/978-1-60761-753-2_15 · DOI
  32. Perez-Pinera, 2012, Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases, Nucleic Acids Res., 40, 3741, 10.1093/nar/gkr1214 · DOI
  33. Duda, 2014, High-efficiency genome editing via 2A-coupled co-expression of fluorescent proteins and zinc finger nucleases or CRISPR/Cas9 nickase pairs, Nucleic Acids Res., 42, e84, 10.1093/nar/gku251 · DOI
  34. Gou, 2007, A novel approach for the construction of multiple shRNA expression vectors, J. Gene Med., 9, 751, 10.1002/jgm.1080 · DOI
  35. Hockemeyer, 2009, Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases, Nat. Biotechnol., 27, 851, 10.1038/nbt.1562 · DOI
  36. DeKelver, 2010, Functional genomics, proteomics, and regulatory DNA analysis in isogenic settings using zinc finger nuclease-driven transgenesis into a safe harbor locus in the human genome, Genome Res., 20, 1133, 10.1101/gr.106773.110 · DOI
  37. Wang, 2014, Genetic screens in human cells using the CRISPR-Cas9 system, Science, 343, 80, 10.1126/science.1246981 · DOI · Paper page
  38. Esvelt, 2013, Orthogonal Cas9 proteins for RNA-guided gene regulation and editing, Nat. Methods, 10, 1116, 10.1038/nmeth.2681 · DOI · Paper page
  39. Fonfara, 2013, Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems, Nucleic Acids Res., 42, 2577, 10.1093/nar/gkt1074 · DOI · Paper page
  40. Beerli, 2000, Chemically regulated zinc finger transcription factors, J. Biol. Chem., 275, 32617, 10.1074/jbc.M005108200 · DOI
  41. Mercer, 2013, Regulation of endogenous human gene expression by ligand-inducible TALE transcription factors, ACS Synthet. Biol.
  42. Polstein, 2012, Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors, J. Am. Chem. Soc., 134, 16480, 10.1021/ja3065667 · DOI
  43. Lombardo, 2007, Gene editing in human stem cells using zinc finger nucleases and integrase-defective lentiviral vector delivery, Nat. Biotechnol., 25, 1298, 10.1038/nbt1353 · DOI · Paper page
  44. Tsai, 2014, Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing, Nat. Biotechnol., 32, 569, 10.1038/nbt.2908 · DOI · Paper page
  45. Nissim, 2014, Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells, Mol. Cell., 54, 698, 10.1016/j.molcel.2014.04.022 · DOI
  46. Gao, 2014, Self-processing of ribozyme-flanked RNAs into guide RNAs in vitro and in vivo for CRISPR-mediated genome editing, J. Integr. Plant Biol., 56, 343, 10.1111/jipb.12152 · DOI
  47. Persons, 2010, Lentiviral vector gene therapy: effective and safe, Mol. Ther., 18, 861, 10.1038/mt.2010.70 · DOI

Cited by

Sorted by citations

Metadata

Authors
Kabadi, A. M., Ousterout, D. G., Hilton, I. B., & Gersbach, C. A.
Venue
Nucleic Acids Research
Published
2014-08-13
Volume
42
Issue
19
Pages
e147-e147
ISSN
  • 1362-4962
  • 0305-1048
Cited by
370
References
14
Language
en

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review