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Darkness facilitates the acoustic startle reflex in humans
Open accessAbstract
The effects of darkness on startle reactivity and prepulse inhibition were investigated in two studies with 25 subjects participating in each study. Acoustic startle stimuli that were or were not preceded by an acoustic prepulse were delivered in alternating periods of complete darkness or light. In both studies, darkness significantly increased the magnitude of startle but did not affect prepulse inhibition (PPI). The PPI results suggest that darkness did not increase attention to the auditory modality, so that the startle facilitation in the dark probably did not result from an attentional process. The increased startle in the dark was significantly correlated with the intensity of subjects' fear of the dark as children based on retrospective rating scales. It is hypothesized that the startle facilitation in the dark results from a change in affect rather than from a change in attention.
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“In contrast to rodents, humans are diurnal and feel more vulnerable in the dark (Schaller et al, 2003), and darkness is sufficiently anxiogenic in humans to potentiate startle (Grillon et al, 1997b). Dark-enhanced startle is replicable across laboratories (Grillon et al, 1999), and can be observed in both adolescents (Grillon et al, 1999) and adults (Coplan et al, 1998; Grillon and Ameli, 1998b;”
From Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety (2010) · cites this paper as Grillon et al, 1997b
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Metadata
- Authors
- Grillon, C., Pellowski, M., Merikangas, K. R., & Davis, M.
- Affiliations
- Yale University (US)
- Corresponding author
- Grillon, Christian
- Venue
- Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 1997-09
- Volume
- 42
- Issue
- 6
- Pages
- 453-460
- ISSN
- 0006-3223 (ISSN-L)
- OpenAlex
- W2090526529
- Cited by
- 193
- References
- 64
- Citations by year
- 2026: 6 · 2025: 2 · 2024: 8 · 2023: 10 · 2022: 5 · 2021: 9 · 2020: 3 · 2019: 3 · 2018: 8 · 2017: 8 · 2016: 8 · 2015: 13 · 2014: 5 · 2013: 7 · 2012: 11
- FWCI
- 4.92
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Biological Psychiatry (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- National Institutes of Health (5r29mh050720-05)
- National Institute of Mental Health (1 R29 MH-50720)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Keywords
- acoustic startle response, darkness, prepulse inhibition, fear of the dark, affect, attention, light and darkness
- MeSH terms
- Acoustic Stimulation, Adult, Anxiety, Attention, Blinking, Darkness, Fear, Female, Humans, Male, Surveys and Questionnaires, Reflex, Startle
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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