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The discovery and development of HMG-CoA reductase inhibitors.
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During the 1950s and 1960s, many cholesterol-lowering agents were reported and introduced into clinical use, in-
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“Nonetheless, TGs have been demonstrated to be correlated with acute pancreatitis655).”
From Japan Atherosclerosis Society (JAS) guidelines for prevention of atherosclerotic cardiovascular diseases 2017 (2018) · cites this paper as [655]
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Mizoi, K., Takahashi, M., Haba, M., & Hosokawa, M. (2015) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2015.12.069 · Cited by 17
Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells
Cong, L., Fu, S., Zhang, J., Zhao, J., & Zhang, Y. (2017) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2017.5353 · Cited by 17
Hottman, D. A., Cheng, S., Gram, A., LeBlanc, K. J., Yuan, L., & Li, L. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.01.026 · Cited by 17
Circulating Mature PCSK9 Level Predicts Diminished Response to Statin Therapy
Kuyama, N., Kataoka, Y., Takegami, M., Nishimura, K., Harada‐Shiba, M., Hori, M., Ogura, M., Otsuka, F., Asaumi, Y., Noguchi, T., et al. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.120.019525 · Cited by 17
Metadata
- Authors
- Endo, A.
- Corresponding author
- Endo, A
- ORCID
- Endo, A
- Venue
- Journal of Lipid Research
- Publisher
- Elsevier BV
- Published
- 1992-11
- Volume
- 33
- Issue
- 11
- Pages
- 1569-1582
- ISSN
- 0022-2275 (ISSN-L)
- OpenAlex
- W2148463229
- Cited by
- 847
- References
- 114
- Citations by year
- 2026: 11 · 2025: 19 · 2024: 31 · 2023: 22 · 2022: 25 · 2021: 26 · 2020: 23 · 2019: 20 · 2018: 35 · 2017: 28 · 2016: 37 · 2015: 41 · 2014: 39 · 2013: 43 · 2012: 35
- FWCI
- 16.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Journal of Lipid Research (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Health Sciences › Medicine › Pharmacology (medical) › Historical Medical Research and Treatments
- Keywords
- statins, cholesterol-lowering drugs, drug discovery, drug development
- MeSH terms
- Animals, Anticholesteremic Agents, Humans, Hypercholesterolemia, Lovastatin, Hydroxymethylglutaryl-CoA Reductase Inhibitors, History, 20th Century
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