Cited by 100Regulation of Appetite and ObesityNutrition, Health and Food BehaviorBiochemical Analysis and Sensing Techniques

A high-protein diet enhances satiety without conditioned taste aversion in the rat

Bensaı̈d, Ahmed, Tomé, Daniel, L'Heureux-Bourdon, Diane, Even, Patrick, Gietzen, Dorothy, Morens, Céline, Gaudichon, Claire, Larue-Achagiotis, Christiane +1 more·2003·Physiology & Behavior

Abstract

In order to determine the respective roles of conditioned food aversion, satiety and palatability, we studied behavioral responses to a 50% total milk protein diet, compared with those to a normal protein diet containing 14% total milk protein. Different paradigms were employed, including meal pattern analysis, two-choice testing, flavor testing, a behavioral satiety sequence (BSS) and taste reactivity. Our experiments showed that only behavioral and food intake parameters were disturbed during the first day when an animal ate the high-protein (P50) diet, and that most parameters returned to baseline values as soon as the second day of P50. Rats adapted to P50 did not acquire a conditioned taste aversion (CTA) but exhibited satiety, and a normal BSS. The initial reduction in high-protein diet intake appeared to result from the lower palatability of the food combined with the satiety effect of the high-protein diet and the delay required for metabolic adaptation to the higher protein level.

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Crossref · 10.1016/s0031-9384(02)00977-0

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Authors
Bensaı̈d, A., Tomé, D., L'Heureux-Bourdon, D., Even, P., Gietzen, D., Morens, C., Gaudichon, C., Larue-Achagiotis, C., & Fromentin, G.
Affiliations
  • Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
  • University of California, Davis (US)
Corresponding author
Fromentin, Gilles
Venue
Physiology & Behavior
Publisher
Elsevier BV
Published
2003-02
Volume
78
Issue
2
Pages
311-320
ISSN
0031-9384 (ISSN-L)
OpenAlex
W2017173142
Cited by
100
References
32
Citations by year
2025: 2 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 4 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 5 · 2016: 5 · 2015: 8 · 2014: 5 · 2013: 3 · 2012: 6
FWCI
1.77
Type
journal article
Language
en
Open access
closed
Locations
  • Physiology & Behavior (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
  • Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
  • Health Sciences › Nursing › Nutrition and Dietetics › Biochemical Analysis and Sensing Techniques
Keywords
high-protein diet, satiety, conditioned taste aversion, dietary intake, palatability, milk protein, taste reactivity, metabolic adaptation, rats
MeSH terms
Animals, Animals, Newborn, Avoidance Learning, Behavior, Animal, Choice Behavior, Conditioning, Psychological, Dose-Response Relationship, Drug, Feeding Behavior, Food Preferences, Grooming, Male, Milk Proteins, Motor Activity, Rest, Satiety Response, Taste, Rats, Wistar, Rats

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