Cellular Senescence

The hallmarks of cancer

Hanahan, D., & Weinberg, R. A. (2000) · Cell · doi:10.1016/s0092-8674(00)81683-9 · Cited by 29,219

The serial cultivation of human diploid cell strains

Hayflick, L., & Moorhead, P. S. (1961) · Experimental Cell Research · doi:10.1016/0014-4827(61)90192-6 · Cited by 8,508

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

Serrano, M., Lin, A. W., McCurrach, M. E., Beach, D., & Lowe, S. W. (1997) · Cell · doi:10.1016/s0092-8674(00)81902-9 · Cited by 5,218 · cited 1×

Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

Bodnar, A. G., Ouellette, M., Frolkis, M., Holt, S. E., Chiu, C.-P., Morin, G. B., Harley, C. B., Shay, J. W., Lichtsteiner, S., & Wright, W. E. (1998) · Science · doi:10.1126/science.279.5349.349 · Cited by 4,975

QUANTITATIVE STUDIES OF THE GROWTH OF MOUSE EMBRYO CELLS IN CULTURE AND THEIR DEVELOPMENT INTO ESTABLISHED LINES

Todaro, G. J., & Green, H. (1963) · The Journal of Cell Biology · doi:10.1083/jcb.17.2.299 · Cited by 2,747

Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA

Blasco, M. A., Lee, H.-W., Hande, M. P., Samper, E., Lansdorp, P. M., DePinho, R. A., & Greider, C. W. (1997) · Cell · doi:10.1016/s0092-8674(01)80006-4 · Cited by 2,108

Tumor Suppression at the Mouse INK4a Locus Mediated by the Alternative Reading Frame Product p19

Kamijo, T., Zindy, F., Roussel, M. F., Quelle, D. E., Downing, J. R., Ashmun, R. A., Grosveld, G., & Sherr, C. J. (1997) · Cell · doi:10.1016/s0092-8674(00)80452-3 · Cited by 1,566

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

Zindy, F., Eischen, C. M., Randle, D. H., Kamijo, T., Cleveland, J. L., Sherr, C. J., & Roussel, M. F. (1998) · Genes & Development · doi:10.1101/gad.12.15.2424 · Cited by 1,245

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells

Kiyono, T., Foster, S. A., Koop, J. I., McDougall, J. K., Galloway, D. A., & Klingelhutz, A. J. (1998) · Nature · doi:10.1038/23962 · Cited by 1,206 · cited 1×

p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

Karlseder, J., Broccoli, D., Dai, Y., Hardy, S., & de Lange, T. (1999) · Science · doi:10.1126/science.283.5406.1321 · Cited by 1,086

Cellular Senescence as a Novel Mechanism of Chronic Inflammation and Cancer Progression

Ohtani, N. (2016) · Springer eBooks · doi:10.1007/978-4-431-56068-5_15

NSDHL Depletion Promotes Cellular Senescence in Mouse Embryonic Fibroblasts

Gabitova, L., & Astsaturov, I. A. (2015) · DOAJ (DOAJ: Directory of Open Access Journals)

Effect of donor cell age on the efficiency of nuclear transfer in rabbits Dr Vasiliy Galat received his PhD in 1997 from the Moscow Biotechnology Institute. He spent 2 years in the Max-Delbruck Center for Molecular Medicine, Berlin as a postdoctoral fellow then moved to the Reproductive Genetics Institute, Chicago. His research interests include fertilization, early mammalian development and cell differentiation.

Galat, V., Lagutina, I., Мезина, М. Н., Прокофьев, М. И., & Zakhartchenko, V. (2001)

Porcine Neural Progenitor Cells Derived from Tissue at Different Gestational Ages Can Be Distinguished by Global Transcriptome

Yang, J., Menges, S. A., Gu, P., Tongbai, R., Samuel, M., Prather, R. S., & Klassen, H. J. (2017) · Cell Transplantation · doi:10.1177/0963689717723015

Characterizing the role of the Retinoblastoma protein LXCXE binding cleft in cellular senescence and tumor suppression

Talluri, S. (2013) · Scholarship@Western (Western University)

Molecular mechanisms of neoplasia

Derkacz, A., & Komosińska‐Vassev, K. (2017) · Annales Academiae Medicae Silesiensis · doi:10.18794/aams/63498

Boosting ATM Activity Promotes Longevity in Nematodes and MicePreprint

Qian, M., Liu, Z., Peng, L., Meng, F., Tang, X., Ao, Y., Shi, L., Zhou, M., Wang, M., Qin, B., et al. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/240606

Pancreatic beta cells turnover: effects of endogenous hyperinsulinemia and amyloid deposits

Montemurro, C. (2012)

Genome-wide epigenetic profiling of B cell leukemia and lymphoma

Morsy, M. H. A. (2019) · Gothenburg University Publications Electronic Archive (Gothenburg University)

Stem Cells in Dystrophic Animal Models: From Preclinical to Clinical Studies

Sitzia, C., Erratico, S., Farini, A., Torrente, Y., & Meregalli, M. (2014) · Stem cell biology and regenerative medicine · doi:10.1007/978-3-319-03572-7_1

Assessing modified chitosan wound dressings to enhance wound healing in the porcine model

Khathide, B. (2020) · UpSpace Institutional Repository (University of Pretoria)

Humpback Whale Cell Lines as an In Vitro Tool for Toxicity Assessment

Burkard, M. (2017) · Griffith Research Online · doi:10.25904/1912/492

13. Croissance, développement post-embryonnaire et régénération

Wolpert, L., Tickle, C. A., Arias, A. M., Lawrence, P. A., Lumsden, A., Robertson, E. J., & Smith, J. (2017) · Dunod eBooks · doi:10.3917/dunod.wolpe.2017.01.0569

Allgemeine Aspekte der Primärkultur

Gstraunthaler, G. J. A., & Lindl, T. (2021) · Springer eBooks · doi:10.1007/978-3-662-62606-1_16 · Cited by 1

β-Cell Replacement Therapy for Type 1 Diabetes

Efrat, S. (2003) · Humana Press eBooks · doi:10.1007/978-1-59259-310-1_31

Cellular Senescence

Palmero, I. (2005) · Springer eBooks · doi:10.1007/3-540-29623-9_3080

Mitotic Senescence in Plants

Gan, S. (2017) · Annual Plant Reviews online · doi:10.1002/9781119312994.apr0262

Anti-Aging Medicine Literature Watch

Pawelec, G. (2000) · Rejuvenation Research · doi:10.1089/rej.1.2000.3.453

Cellular Aging and Metabolites in Aging

Kondoh, H., Mikawa, T., & Kameda, M. (2022) · Springer eBooks · doi:10.1007/978-981-16-7977-3_4

A senescence-like state is beneficial for ovarian cancer treatmentPreprint

Skulimowski, M., Calvo, L., Cheng, S., Clément, I., Portelance, L., Zhan, Y., Carmona, E., Lafontaine, J., de Ladurantaye, M., Rahimi, K., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.09.30.560300

Establishment and Characterization of an Immortalized Oviduct Epithelial Cell Line from Yak (Bos grunniens)

Cai, W., Jiang, Y., Xu, X., Ma, Q., Xu, C., Fu, W., & Lan, D. (2025) · Animals · doi:10.3390/ani15172509

Cellular dynamics in the niche of infrequently dividing hair follicle stem cells in the mouse Mus musculus

Zhang, Y. (2010) · eCommons (Cornell University)

Relevance of Mitochondrial Functions and Plasticity in Tumor Biology

Obre, É., Bellancé, N., José, C., Bénard, G., Nouette‐Gaulain, K., & Rossignol, R. (2014) · Springer eBooks · doi:10.1007/978-94-017-8984-4_11

Additional file 1 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26632998

Additional file 6 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633013

Additional file 4 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633007

Additional file 5 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633010

Additional file 7 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633016

Additional file 8 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633019

Additional file 11 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633028

Additional file 10 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633025

Additional file 3 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633004

Additional file 9 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633022

Additional file 2 of Bovine oviductal organoids: a multi-omics approach to capture the cellular and extracellular molecular response of the oviduct to heat stress

Menjivar, N. G., Gad, A., Thompson, R. E., Meyers, M. A., Hollinshead, F., & Tesfaye, D. (2024) · Figshare · doi:10.6084/m9.figshare.26633001

Implication des protéines HMGA et HMGA2 dans les changements du programme de réplication au cours de la sénescence cellulaire

Kahli, M. (2011) · theses.fr (ABES) · doi:10.70675/bc7bcb93z46bdz473aza3ebz5cc713b77897

Roles of the multifunctional protein E4F1 in cellular senescence

Maciejewska, Z. (2010) · theses.fr (ABES) · doi:10.70675/21f99f8bze775z413fza364z48dd293ca460

Télomerase et destin des tumeurs neuroblastiques

Samy, M. (2010) · theses.fr (ABES) · doi:10.70675/07050b7dz1056z4e65za6f1z34cea95a398b

Functional CRISPR Screens Define Genetic Drivers for Cancer Transformation and Progression from Non-Cancerous Cells

Ma, S., Li, Y., & Fei, T. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27073223

Hépatocytes différenciés à partir de cellules souches pluripotentes induites : modèle pour la thérapie cellulaire et génique autologue de l'hémophilie B et modèle préclinique chez le primate

Luce, E. (2017) · theses.fr (ABES) · doi:10.70675/ac4516a9z0ec1z4655z97daz547d512b3fc9

Modulation de la sénescence induite par les oncogènes par les glucocorticoïdes et rôle de EGR1

Carvalho, C. (2018) · theses.fr (ABES) · doi:10.70675/7cafc6a4za30dz467dz81a1z7033a7846a52

Cellules souches dérivées du muscle humain « MuStem » : modalités de préparation in vitro et caractéristiques biologiques pour une application clinique

Saury, C. (2017) · theses.fr (ABES) · doi:10.70675/5ad5ac21z12afz4845zb3e5zb9716e79df0b

Generation of antisense RNAs at convergent gene loci in cells undergoing senescence

Deb, M. K. (2016) · theses.fr (ABES) · doi:10.70675/739ebf07zf620z4e1fzb0d4z02066589491f

Impact of aging on cardiac mesenchymal stromal cells

Martini, H. (2019) · theses.fr (ABES) · doi:10.70675/bb7ddcb3z0b6az4c39za6eczc94e0563f0a3

Senolytic drug discovery and mechanisms of action in BRAF-V600E oncogene-induced senescence

L’Hôte, V. (2022) · theses.fr (ABES) · doi:10.70675/acd5f426zc1b2z446fz8404z0f8f121081f8

Research progress in the anti-aging potential of neural stem cells

Wu, J.-C., Yang, J.-Y., Li, N., & Liu, J. (2025) · Nature Advance · doi:10.61958/natx7823

Extracellular ATP drives tryptophan metabolism and aryl hydrocarbon receptor activation to promote cellular senescence

Volonté, D., Mullett, S. J., Gelhaus, S. L., & Galbiati, F. (2026) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2026.113094

Fundamental Principles of Cell Culture

Badal, S. (2026) · Springer eBooks · doi:10.1007/978-3-032-28873-8_3

Metformin modulates autophagy in heterozygous and CRISPR-edited TSC2 primary fibroblastsPreprint

Viola, G. D., Brum, P. O., Garcia, A. B. D. M., Jaeger, M. D. C., Freire, N., Filippi‐Chiela, E. C., Baldo, G., Poletto, É., Ashton‐Prolla, P., & Rosset, C. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.08.11.743350

Apical-Out Ileal Organoids: A Versatile Platform for Probing Gut-Nanomaterial InteractionsPreprint

Vo, D. S., Meyer, A., Tzioufa, F., Eriksson, J., Lopes, A. C. C., Martino, M. L. D., Fijalkowski, W., Rae, J., Björner, K., Vessby, J., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.10.10.758216

Mosaicism for trisomy21: Utility of array-based technology for its detection and its influence on telomere length and the frequency of acquired chromosome abnormalities

Charalsawadi, C. (2011) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/yfrf-z457

Oncogenic Stress Responses

Bulavin, D. V. (2010) · Elsevier eBooks · doi:10.1016/b978-0-12-374145-5.00271-0

Mechanisms of cellular senescence in human and mouse cells.

Itahana, K., Campisi, J., & Dimri, G. P. (2004) · Biogerontology · doi:10.1023/b:bgen.0000017682.96395.10 · Cited by 338

Replicative senescence: a critical review

Cristofalo, V. J., Lorenzini, A., Allen, R. G., Torres, C. A., & Tresini, M. (2004) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2004.07.010 · Cited by 285

A Comparison of Senescence in Mouse and Human Cells

Gorbunova, V. A., & Seluanov, A. (2009) · Springer eBooks · doi:10.1007/978-1-4419-1075-2_7 · Cited by 2

The role of replicative senescence in cancer and human ageing: utility (or otherwise) of murine models

Smith, S. K., & Kipling, D. (2004) · Cytogenetic and Genome Research · doi:10.1159/000078219 · Cited by 17

Molecular Mechanisms of Cellular Senescence

Becker, T. M., & Haferkamp, S. (2013) · InTech eBooks · doi:10.5772/54120 · Cited by 17