Cited by 879Circadian rhythm and melatoninLight effects on plantsSleep and Work-Related Fatigue

The DOI matches its Crossref record; 44 of the 46 references it cites were found in a registry or an index.

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

Open access

Albrecht, Urs, Sun, Zhong Sheng, Eichele, Gregor, Lee, Cheng Chi·1997·Cell

Open this paper in CoChat — free account Open PDF

Abstract

A mouse gene, mper1, having all the properties expected of a circadian clock gene, was reported recently. This gene is expressed in a circadian pattern in the suprachiasmatic nucleus (SCN). mper1 maintains this pattern of circadian expression in constant darkness and can be entrained to a new light/dark cycle. Here we report the isolation of a second mammalian gene, mper2, which also has these properties and greater homology to Drosophila period. Expression of mper1 and mper2 is overlapping but asynchronous by 4 hr. mper1, unlike period and mper2, is expressed rapidly after exposure to light at CT22. It appears that mper1 is the pacemaker component which responds to light and thus mediates photic entrainment.

Integrity signals

Registry

Crossref · 10.1016/s0092-8674(00)80495-x

Cites

44 of 44 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589
Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669
Clock Mutants of Drosophila melanogaster
Konopka, R. J., & Benzer, S. (1971) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.68.9.2112 · Cited by 2,287
Transplanted Suprachiasmatic Nucleus Determines Circadian Period
Ralph, M. R., Foster, R. G., Davis, F. C., & Menaker, M. (1990) · Science · doi:10.1126/science.2305266 · Cited by 1,853
Positional Cloning of the Mouse Circadian Gene
King, D. P., Zhao, Y., Sangoram, A. M., Wilsbacher, L. D., Tanaka, M., Antoch, M. P., Steeves, T. D. L., Vitaterna, M. H., Kornhauser, J. M., Lowrey, P. L., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80245-7 · Cited by 1,382
A retinohypothalamic projection in the rat
Moore, R. Y., & Lenn, N. J. (1972) · The Journal of Comparative Neurology · doi:10.1002/cne.901460102 · Cited by 1,263
Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels
Hardin, P. E., Hall, J. C., & Rosbash, M. (1990) · Nature · doi:10.1038/343536a0 · Cited by 1,156
Temporal Organization: Reflections of a Darwinian Clock-Watcher
Pittendrigh, C. S. (1993) · Annual Review of Physiology · doi:10.1146/annurev.ph.55.030193.000313 · Cited by 1,023
Prediction of the Coding Sequences of Unidentified Human Genes. IX. The Complete Sequences of 100 New cDNA Clones from Brain Which Can Code for Large Proteins in vitro
Nagase, T. (1998) · DNA Research · doi:10.1093/dnares/5.1.31 · Cited by 844
Circadian oscillation of a mammalian homologue of the Drosophila period gene
Tei, H., Okamura, H., Shigeyoshi, Y., Fukuhara, C., Ozawa, R., Hirose, M., & Sakaki, Y. (1997) · Nature · doi:10.1038/39086 · Cited by 792

Show all 46 references

Research works printed but not linked: 1

Card, J.P., and Moore, R.Y. (1991). The organization of visual circuits influencing the circadian activity of the suprachiasmatic nucleus. In Suprachiasmatic Nucleus: The Mind's Clock, D.C. Klein, R.Y. Moore, and S.M. Reppert, eds. (New York, Oxford University Press) 51–76.

Sorted by citations

Items 401–500 of 877

The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments
Bellet, M. M., Stincardini, C., Costantini, C., Gargaro, M., Pieroni, S., Castelli, M., Piobbico, D., Sassone‐Corsi, P., Fazia, M. A. D., Romani, L. R., et al. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22062974 · Cited by 46
The Ventral Tegmental Area and Nucleus Accumbens as Circadian Oscillators: Implications for Drug Abuse and Substance Use Disorders
Becker‐Krail, D. D., Walker, W. H., & Nelson, R. J. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.886704 · Cited by 48
Circadian Rhythms and the Transcriptional Feedback Loop (Nobel Lecture)**
Rosbash, M. (2021) · Angewandte Chemie International Edition · doi:10.1002/anie.202015199 · Cited by 46
Activation of 5-HT2C receptors acutely induces Per gene expression in the rat suprachiasmatic nucleus at night
Varcoe, T. J., Kennaway, D. J., & Voultsios, A. (2003) · Molecular Brain Research · doi:10.1016/j.molbrainres.2003.09.010 · Cited by 46
Dimorphic Effects of Leptin on the Circadian and Hypocretinergic Systems of Mice
Mendoza, J., López-López, C., Revel, F. G., Jeanneau, K., Delerue, F., Prinssen, E. P. M., Challet, É., Moreau, J., & Grundschober, C. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.02072.x · Cited by 45
MOLECULAR CLONING, TISSUE DISTRIBUTION, AND DAILY RHYTHMS OF EXPRESSION OFPER1GENE IN EUROPEAN SEA BASS (DICENTRARCHUS LABRAX)
Sánchez, J. A., Madrid, J. A., & Sánchez‐Vázquez, F. J. (2010) · Chronobiology International · doi:10.3109/07420520903398633 · Cited by 45
FEEDING-INDUCED RAPID RESETTING OF THE HEPATIC CIRCADIAN CLOCK IS ASSOCIATED WITH ACUTE INDUCTION OFPER2ANDDEC1TRANSCRIPTION IN RATS
Wu, T., Ni, Y., Kato, H., & Fu, Z. (2010) · Chronobiology International · doi:10.3109/07420520903398625 · Cited by 45
Sleep Deprivation and Caffeine Treatment Potentiate Photic Resetting of the Master Circadian Clock in a Diurnal Rodent
Jha, P. K., Bouâouda, H., Gourmelen, S., Dumont, S., Fuchs, F., Goumon, Y., Bourgin, P., Kalsbeek, A., & Challet, É. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3241-16.2017 · Cited by 48
Circadian genes in a blind subterranean mammal II: Conservation and uniqueness of the three Period homologs in the blind subterranean mole rat, Spalax ehrenbergi superspecies
Avivi, A., Oster, H., Joel, A., Beiles, A., Albrecht, U., & Nevo, E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.182423299 · Cited by 45
Self-citation
Light-Induced Phase Shifts in Mice Lacking mPER1 or mPER2
Bae, K., & Weaver, D. R. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403252248 · Cited by 47
Photoreception and circadian clock system of the chicken pineal gland
Okano, T., & Fukada, Y. (2001) · Microscopy Research and Technique · doi:10.1002/jemt.1070 · Cited by 45
The tim SL Mutant Affects a Restricted Portion of the Drosophila melanogaster Circadian Cycle
Rutila, J. E., Maltseva, O. N., & Rosbash, M. (1998) · Journal of Biological Rhythms · doi:10.1177/074873098129000200 · Cited by 44
Dopamine 2 Receptor Activation Entrains Circadian Clocks in Mouse Retinal Pigment Epithelium
Baba, K., DeBruyne, J. P., & Tosini, G. (2017) · Scientific Reports · doi:10.1038/s41598-017-05394-x · Cited by 44
Bidirectional CLOCK/BMAL1-dependent circadian gene regulation by retinoic acid in vitro
Shirai, H., Oishi, K., & Ishida, N. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.10.031 · Cited by 44
Signaling to the Mammalian Circadian Clocks: In Pursuit of the Primary Mammalian Circadian Photoreceptor
Pando, M. P., & Sassone‐Corsi, P. (2001) · Science Signaling · doi:10.1126/stke.2001.107.re16 · Cited by 48
Negative Control of Circadian Clock Regulator E4BP4 by Casein Kinase Iϵ-Mediated Phosphorylation
Doi, M., Okano, T., Yujnovsky, I., Sassone‐Corsi, P., & Fukada, Y. (2004) · Current Biology · doi:10.1016/j.cub.2004.05.043 · Cited by 43
Low-Salt Diet and Circadian Dysfunction Synergize to Induce Angiotensin II–Dependent Hypertension in Mice
Pati, P., Fulton, D. J., Bagi, Z. A., Chen, F., Wang, Y., Kitchens, J., Cassis, L. A., Stepp, D. W., & Rudic, R. D. (2016) · Hypertension · doi:10.1161/hypertensionaha.115.06194 · Cited by 47
Brain Control of Embryonic Circadian Rhythms in the Silkmoth Antheraea pernyi
Šauman, I., & Reppert, S. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)81012-0 · Cited by 43
Molecular cloning and daily variations of the Period gene in a reef fish Siganus guttatus
Park, J., Park, Y., Sugama, N., Kim, S., & Takemura, A. (2006) · Journal of Comparative Physiology A · doi:10.1007/s00359-006-0194-6 · Cited by 43
Hypothalamic Circadian Organization in Birds. II. Clock Gene Expression
Abraham, U., Albrecht, U., & Brandstätter, R. (2003) · Chronobiology International · doi:10.1081/cbi-120022414 · Cited by 43
Self-citation
Generalization and Discovery by Assuming Conserved Mechanisms: Cross-Species Research on Circadian Oscillators
Bechtel, W. (2009) · Philosophy of Science · doi:10.1086/605790 · Cited by 43
Circadian Oscillations of Molecular Clock Components in the Cerebellar Cortex of the Rat
Rath, M. F., Rohde, K., & Møller, M. (2012) · Chronobiology International · doi:10.3109/07420528.2012.728660 · Cited by 42
Initial demonstration of rhythmic Per gene expression in the hypothalamus of a non-mammalian vertebrate, the house sparrow
Brandstätter, R., Abraham, U., & Albrecht, U. (2001) · Neuroreport · doi:10.1097/00001756-200105080-00023 · Cited by 42
Self-citation
Circadian Behaviour in Neuroglobin Deficient Mice
Hundahl, C. A., Fahrenkrug, J., Hay‐Schmidt, A., Georg, B., Faltoft, B., & Hannibal, J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034462 · Cited by 42
From light to genes moving the hands of the circadian clock
Golombek, D. A. (2003) · Frontiers in bioscience · doi:10.2741/1038 · Cited by 42
Expression of haPer1 and haBmal1 in Syrian Hamsters: Heterogeneity of Transcripts and Oscillations in the Periphery
Tong, Y., Guo, H., Brewer, J. M., Lee, H. B., Lehman, M. N., & Bittman, E. L. (2004) · Journal of Biological Rhythms · doi:10.1177/0748730403262871 · Cited by 42
Phenotype of Per1- and Per2- expressing neurons in the suprachiasmatic nucleus of a diurnal rodent ( Arvicanthis ansorgei ): comparison with a nocturnal species, the rat
Dardente, H., Klosen, P., Caldelas, I., Pévet, P., & Masson‐Pévet, M. (2002) · Cell and Tissue Research · doi:10.1007/s00441-002-0609-9 · Cited by 44
A role for Timeless in epithelial morphogenesis during kidney development
Li, Z., Stuart, R. O., Qiao, J., Pavlova, A. V., Bush, K. T., Pöhl, M., Sakurai, H., & Nigám, S. K. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.18.10038 · Cited by 42
Clock Gene Expression in the Suprachiasmatic Nucleus of Hibernating Arctic Ground Squirrels
Ikeno, T., Williams, C. T., Buck, C. L., Barnes, B. M., & Yan, L. (2017) · Journal of Biological Rhythms · doi:10.1177/0748730417702246 · Cited by 39
Circadian gene expression and extremely low‐frequency magnetic fields: An in vitro study
Manzella, N., Bracci, M., Ciarapica, V., Staffolani, S., Strafella, E., Rapisarda, V., Valentino, M., Amati, M., Copertaro, A., & Santarelli, L. (2015) · Bioelectromagnetics · doi:10.1002/bem.21915 · Cited by 40
Role of monochromatic light on daily variation of clock gene expression in the pineal gland of chick
Jiang, N., Wang, Z., Cao, J., Dong, Y., & Chen, Y. (2016) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2016.09.020 · Cited by 40
Light affects behavioral despair involving the clock gene Period 1
Olejniczak, I., Ripperger, J. A., Sandrelli, F., Schnell, A., Mansencal-Strittmatter, L., Wendrich, K. S., Hui, K. Y., Brenna, A., Fredj, N. B., & Albrecht, U. (2021) · PLoS Genetics · doi:10.1371/journal.pgen.1009625 · Cited by 41
Self-citation
Role for the NR2B subunit of the N ‐methyl‐ d ‐aspartate receptor in mediating light input to the circadian system
Wang, L. M., Schroeder, A., Loh, D. H., Smith, D., Lin, K., Han, J.-H., Michel, S. H., Hummer, D. L., Ehlen, J. C., Albers, H. E., et al. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06144.x · Cited by 39
Functional and evolutionary implications of natural variation in clock genes
Costa, R., & Kyriacou, C. P. (1998) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(98)80096-2 · Cited by 39
M�ller glial cells in anuran retina
Bringmann, A., Skatchkov, S. N., Pannicke, T., Biedermann, B., Wolburg, H., Orkand, R. K., & Reichenbach, A. (2000) · Microscopy Research and Technique · doi:10.1002/1097-0029(20000901)50:5 · Cited by 24
Modeling the Molecular Calendar
Hastings, M. H. (2001) · Journal of Biological Rhythms · doi:10.1177/074873001129001818 · Cited by 40
Regulation of circadian gene expression in the kidney by light and food cues in rats
Wu, T., Ni, Y., Dong, Y., Xu, J., Song, X., Kato, H., & Fu, Z. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00578.2009 · Cited by 37
Untimely oxidative stress in β-cells leads to diabetes – Role of circadian clock in β-cell function
Lee, J. M., Ma, K., Moulik, M., & Yechoor, V. K. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.02.022 · Cited by 40
Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacy
Kim, D. W., Chang, C., Chen, X., Doran, A. C., Gaudreault, F., Wager, T. T., DeMarco, G. J., & Kim, J. K. (2019) · Molecular Systems Biology · doi:10.15252/msb.20198838 · Cited by 38
Modulation of mPer1 gene expression by anxiolytic drugs in mouse cerebellum
Akiyama, M., Kirihara, T., Takahashi, S., Minami, Y., Yoshinobu, Y., Moriya, T., & Shibata, S. (1999) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0702957 · Cited by 38
Circadian expression of clock genes during ontogeny in the rat heart
Sakamoto, K., Oishi, K., Nagase, T., Miyazaki, K., & Ishida, N. (2002) · Neuroreport · doi:10.1097/00001756-200207190-00003 · Cited by 38
Rhythmicity of the cGMP-related signal transduction pathway in the mammalian circadian system
Ferreyra, G. A., & Golombek, D. A. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.5.r1348 · Cited by 38
Molecular Neurogenetics of Biological Rhythms
Hall, J. C. (1998) · Journal of Neurogenetics · doi:10.3109/01677069809108556 · Cited by 38
How cells tell time
Green, C. (1998) · Trends in Cell Biology · doi:10.1016/s0962-8924(98)01269-0 · Cited by 38
Genetics of circadian rhythms
Vitaterna, M. H., Shimomura, K., & Jiang, P. (2019) · Neurologic Clinics · doi:10.1016/j.ncl.2019.05.002 · Cited by 36
Sleep and biorythm disturbances in schizophrenia, mood and anxiety disorders: a review
Bersani, F. S., Iannitelli, A., Pacitti, F., & Bersani, G. (2012) · Rivista di psichiatria · doi:10.1708/1175.13027 · Cited by 40
Bone endocrine regulation of energy metabolism and male reproduction
Karsenty, G. (2011) · Comptes Rendus Biologies · doi:10.1016/j.crvi.2011.07.007 · Cited by 36
Time to learn: The role of the molecular circadian clock in learning and memory
Smies, C. W., Bodinayake, K. K., & Kwapis, J. L. (2022) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2022.107651 · Cited by 35
Acute systemic inflammation transiently synchronizes clock gene expression in equine peripheral blood
Murphy, B. A., Vick, M. M., Sessions, D. R., Cook, R. F., & Fitzgerald, B. P. (2006) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2006.11.002 · Cited by 37
Circadian systems: different levels of complexity
Roenneberg, T., & Merrow, M. W. (2001) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2001.0969 · Cited by 37
mPer1 and mPer2 mutant mice show regular spatial and contextual learning in standardized tests for hippocampus-dependent learning
Zueger, M., Urani, A., Chourbaji, S., Zacher, C., Lipp, H., Albrecht, U., Spanagel, R., Wolfer, D. P., & Gass, P. (2005) · Journal of Neural Transmission · doi:10.1007/s00702-005-0322-4 · Cited by 36
Self-citation
Regional circadian period difference in the suprachiasmatic nucleus of the mammalian circadian center
Koinuma, S., Asakawa, T., Nagano, M., Furukawa, K., Sujino, M., Masumoto, K., Nakajima, Y., Hashimoto, S., Yagita, K., & Shigeyoshi, Y. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12308 · Cited by 35
Dark pulse resetting of the suprachiasmatic clock in Syrian hamsters: behavioral phase-shifts and clock gene expression
Mendoza, J., Dardente, H., Escobar, C., Pévet, P., & Challet, É. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.05.026 · Cited by 36
Light‐ and clock‐dependent regulation of ribosomal S6 kinase activity in the suprachiasmatic nucleus
Butcher, G. Q., Lee, B., Hsieh, F., & Obrietan, K. H. (2004) · European Journal of Neuroscience · doi:10.1111/j.0953-816x.2004.03155.x · Cited by 36
Central Circadian Clock Regulates Energy Metabolism
Ding, G., Gong, Y., Eckel-Mahan, K. L., & Sun, Z. (2018) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-13-1286-1_5 · Cited by 33
Self-citation
Geographic Information System and Remote Sensing Applications in Flood Hazards Management: A Review
Lawal, D. U., Matori, A. N., Hashim, A. M., Chandio, I. A., Sabri, S., Balogun, A., & Haruna, A. A. (2011) · Research Journal of Applied Sciences Engineering and Technology · Cited by 35
Endocrine effects of exposure to artificial light at night: A review and synthesis of knowledge gaps
Grunst, M. L., & Grunst, A. S. (2023) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2023.111927 · Cited by 35
Setting the main circadian clock of a diurnal mammal by hypocaloric feeding
Mendoza, J., Gourmelen, S., Dumont, S., Ciocca, D., Pévet, P., & Challet, É. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.230300 · Cited by 35
Circadian regulation of prion protein messenger RNA in the rat forebrain: a widespread and synchronous rhythm
Cagampang, F. R. A., Whatley, S. A., Mitchell, A., Powell, J. F., Campbell, I. C., & Coen, C. W. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00092-5 · Cited by 34
A Model of Molecular Circadian Clocks: Multiple Mechanisms for Phase Shifting and a Requirement for Strong Nonlinear Interactions
Scheper, T. V. O., Klinkenberg, D., van Pelt, J., & Pennartz, C. M. A. (1999) · Journal of Biological Rhythms · doi:10.1177/074873099129000623 · Cited by 36
Effect of circadian rhythm disturbance on morphine preference and addiction in male rats: Involvement of period genes and dopamine D1 receptor
Garmabi, B., Vousooghi, N., Vosough, M., Yoonessi, A., Bakhtazad, A., & Zarrindast, M.-R. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.02.019 · Cited by 34
Clocking In Time to Gate Memory Processes: The Circadian Clock Is Part of the Ins and Outs of Memory
Rawashdeh, O., Parsons, R., & Maronde, E. (2018) · Neural Plasticity · doi:10.1155/2018/6238989 · Cited by 34
Molecular Mechanism of Mammalian Circadian Clock
Isojima, Y. (2003) · The Journal of Biochemistry · doi:10.1093/jb/mvg219 · Cited by 35
CONES ARE REQUIRED FOR NORMAL TEMPORAL RESPONSES TO LIGHT OF PHASE SHIFTS AND CLOCK GENE EXPRESSION
Dollet, A., Albrecht, U., Cooper, H. M., & Dkhissi‐Benyahya, O. (2010) · Chronobiology International · doi:10.3109/07420521003695704 · Cited by 37
Self-citation
The Suprachiasmatic Nucleus
Pickard, G. E., & Sollars, P. J. (2008) · Elsevier eBooks · doi:10.1016/b978-012370880-9.00283-8 · Cited by 34
Synchronization and phase-resetting by glutamate of an immortalized SCN cell line
Hurst, W. J., Mitchell, J. W., & Gillette, M. U. (2002) · Biochemical and Biophysical Research Communications · doi:10.1016/s0006-291x(02)02346-x · Cited by 32
When does it start ticking? Ontogenetic development of the mammalian circadian system
Christ, E., Korf, H., & von Gall, C. (2012) · Progress in brain research · doi:10.1016/b978-0-444-59427-3.00006-x · Cited by 33
Circadian neurogenetics of mood disorders
Mendoza, J., & Vanotti, G. (2019) · Cell and Tissue Research · doi:10.1007/s00441-019-03033-7 · Cited by 34
The molecular clock in the skin, its functionality, and how it is disrupted in cutaneous melanoma: a new pharmacological target?
de Assis, L. V. M., Moraes, M. N., & Castrucci, A. M. D. L. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03183-5 · Cited by 33
PER2 mediates CREB-dependent light induction of the clock gene Per1
Brenna, A., Ripperger, J. A., Sarò, G., Glauser, D. A., Yang, Z., & Albrecht, U. (2021) · Scientific Reports · doi:10.1038/s41598-021-01178-6 · Cited by 37
Self-citation
MELANOPSIN AND CLOCK GENES: REGULATION BY LIGHT AND ENDOTHELIN IN THE ZEBRAFISH ZEM-2S CELL LINE
Farhat, F. P., Martins, C. B., de Lima, L. H. R. G., Isoldi, M. C., & Castrucci, A. M. D. L. (2009) · Chronobiology International · doi:10.1080/07420520903249005 · Cited by 33
Genetic insights on sleep schedules: this time, it's PERsonal
Chong, S. Y. C., Ptáček, L. J., & Fu, Y. (2012) · Trends in Genetics · doi:10.1016/j.tig.2012.08.002 · Cited by 34
Evidence of an oscillating peripheral clock in an equine fibroblast cell line and adipose tissue but not in peripheral blood
Murphy, B. A., Vick, M. M., Sessions, D. R., Cook, R. F., & Fitzgerald, B. P. (2006) · Journal of Comparative Physiology A · doi:10.1007/s00359-006-0108-7 · Cited by 33
Circadian expression of the clock gene Per2 is altered in the ruin lizard (Podarcis sicula) when temperature changes
Magnone, M. C., Jacobmeier, B., Bertolucci, C., Foà, A., & Albrecht, U. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.10.014 · Cited by 33
Self-citation
Light‐induced phase‐shifts in the circadian expression rhythm of mammalian Period genes in the mouse heart
Sakamoto, K., & Ishida, N. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00302.x · Cited by 33
Involvement of calcium/calmodulin‐dependent protein kinase II in the induction of mPer1
Nomura, K., Takeuchi, Y., Yamaguchi, S., Okamura, H., & Fukunaga, K. (2003) · Journal of Neuroscience Research · doi:10.1002/jnr.10581 · Cited by 33
Genetic clock of biologic rhythms
Badiu, C. (2003) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2003.tb00243.x · Cited by 32
Beyond vision: effects of light on the circadian clock and mood-related behaviours
Stewart, D., & Albrecht, U. (2025) · npj Biological Timing and Sleep · doi:10.1038/s44323-025-00029-1 · Cited by 34
Self-citation
Suppressed cellular oscillations in after‐hours mutant mice are associated with enhanced circadian phase‐resetting
Guilding, C., Scott, F., Bechtold, D. A., Brown, T. M., Wegner, S., & Piggins, H. D. (2012) · The Journal of Physiology · doi:10.1113/jphysiol.2012.242198 · Cited by 32
Neuropeptide‐mediated calcium signaling in the suprachiasmatic nucleus network
Irwin, R. P., & Allen, C. N. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07411.x · Cited by 32
Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders
Shih, B. B.-J., Nirmal, A. J., Headon, D. J., Akbar, A. N., Mabbott, N. A., & Freeman, T. C. (2016) · The Journal of Pathology · doi:10.1002/path.4864 · Cited by 33
The Per2 Negative Feedback Loop Sets the Period in the Mammalian Circadian Clock Mechanism
Wilkins, A. K., Barton, P. I., & Tidor, B. (2007) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0030242 · Cited by 32
Effect of Haloperidol on mPer1 Gene Expression in Mouse Suprachiasmatic Nuclei
Viyoch, J., Matsunaga, N., Yoshida, M., To, H., Higuchi, S., & Ohdo, S. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411704200 · Cited by 32
Photoperiodic regulation of PER1 and PER2 protein expression in rat peripheral tissues
Bendová, Z., & Sumová, A. (2006) · Physiological Research · doi:10.33549/physiolres.930849 · Cited by 32
Timed hypocaloric feeding and melatonin synchronize the suprachiasmatic clockwork in rats, but with opposite timing of behavioral output
Caldelas, I., Feillet, C. A., Dardente, H., Eclancher, F., Malan, A., Gourmelen, S., Pévet, P., & Challet, É. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04284.x · Cited by 33
Transgenic TGR(mREN2)27 Rats as a Model for Disturbed Circadian Organization at the Level of the Brain, the Heart, and the Kidneys
Lemmer, B., Witte, K. K., Enzminger, H., Schiffer, S., & Hauptfleisch, S. (2003) · Chronobiology International · doi:10.1081/cbi-120022407 · Cited by 32
Why the Rat-1 Fibroblast Should Replace the SCN as the In Vitro Model of Choice
Rosbash, M. (1998) · Cell · doi:10.1016/s0092-8674(00)81197-6 · Cited by 32
Invited Review: Sleeping flies don't lie: the use ofDrosophila melanogasterto study sleep and circadian rhythms
Hendricks, J. C. (2003) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00904.2002 · Cited by 32
Circadian Misalignment and Metabolic Disorders: A Story of Twisted Clocks
Woller, A., & Gonze, D. (2021) · Biology · doi:10.3390/biology10030207 · Cited by 36
The circadian clock component PERIOD2
Ripperger, J. A., & Albrecht, U. (2012) · Progress in brain research · doi:10.1016/b978-0-444-59427-3.00014-9 · Cited by 31
Self-citation
Cellular and molecular basis of circadian timing in mammals
Reppert, S. M. (2000) · Seminars in Perinatology · doi:10.1053/sper.2000.9122 · Cited by 32
Light and GABAA receptor activation alter Period mRNA levels in the SCN of diurnal Nile grass rats
Novak, C. M., Ehlen, J. C., Paul, K. N., Fukuhara, C., & Albers, H. E. (2006) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2006.05166.x · Cited by 31
Expression Profiles of PER2 Immunoreactivity Within the Shell and Core Regions of the Rat Suprachiasmatic Nucleus: Lack of Effect of Photic Entrainment and Disruption by Constant Light
Beaulé, C., Houle, L. M., & Amir, S. (2003) · Journal of Molecular Neuroscience · doi:10.1385/jmn:21:2:133 · Cited by 32
Circadian clocks in mood-related behaviors
Albrecht, U. (2010) · Annals of Medicine · doi:10.3109/07853891003677432 · Cited by 31
Self-citation
Light exposure during daytime modulates expression of Per1 and Per2 clock genes in the suprachiasmatic nuclei of mice
Challet, É., Poirel, V., Malan, A., & Pévet, P. (2003) · Journal of Neuroscience Research · doi:10.1002/jnr.10616 · Cited by 34
PASting together the mammalian clock
Whitmore, D., Sassone‐Corsi, P., & Foulkes, N. S. (1998) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(98)80092-5 · Cited by 31
CLOCK GENES OF MAMMALIAN CELLS: PRACTICAL IMPLICATIONS IN TISSUE CULTURE
Kaeffer, B., & Pardini, L. (2005) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-005-0001-7 · Cited by 34
Expression of clock genes in the suprachiasmatic nucleus: Effect of environmental lighting conditions
Yan, L. (2009) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-009-9121-9 · Cited by 30
Evolutionary History of the Vertebrate Period Genes
von Schantz, M., Jenkins, A. K., & Archer, S. N. (2006) · Journal of Molecular Evolution · doi:10.1007/s00239-005-0185-1 · Cited by 30
CirGRDB: a database for the genome-wide deciphering circadian genes and regulators
Li, X., Shi, L., Zhang, K., Wei, W., Liu, Q., Mao, F., Li, J., Cai, W., Chen, H., Teng, H., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx944 · Cited by 35
Self-citation

Authors: Albrecht, U., Sun, Z. S., Eichele, G., & Lee, C. C.
Affiliations: Baylor College of Medicine (US)
Corresponding author: Lee, Cheng Chi
ORCID: Albrecht, Urs
Sun, Zhong Sheng
Lee, Cheng Chi
Venue: Cell
Publisher: Elsevier BV
Published: 1997-12
Volume: 91
Issue: 7
Pages: 1055-1064
ISSN: 0092-8674 (ISSN-L)
DOI: 10.1016/s0092-8674(00)80495-x
OpenAlex: W2151468131
Cited by: 879
References: 46
Citations by year: 2026: 6 · 2025: 7 · 2024: 15 · 2023: 14 · 2022: 16 · 2021: 27 · 2020: 17 · 2019: 20 · 2018: 16 · 2017: 27 · 2016: 27 · 2015: 22 · 2014: 29 · 2013: 28 · 2012: 26
FWCI: 15.79
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 5707 d)
Locations: Cell (publishedVersion)
PubMed (publishedVersion)
MPG.PuRe (Max Planck Society) (submittedVersion)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Keywords: mPer1, mPer2, clock genes, light entrainment, suprachiasmatic nucleus, light response, circadian pacemaker
MeSH terms: Amino Acid Sequence, Animals, Circadian Rhythm, Light, Male, Mice, Inbred C57BL, Molecular Sequence Data, Nuclear Proteins, Transcription Factors, Gene Expression, DNA, Complementary, Cell Cycle Proteins, Mice, Period Circadian Proteins

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

A Differential Response of Two Putative Mammalian Circadian Regulators, mper1and mper2, to Light

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks