Cited by 36Circadian rhythm and melatoninSleep and Wakefulness ResearchSleep and Work-Related Fatigue

Genetics of circadian rhythms

Open access
Vitaterna, Martha Hotz, Shimomura, Kazuhiro, Jiang, Peng·2019·Neurologic Clinics

Abstract

In mammals, genetic influences of circadian rhythms occur at many levels. A set of core "clock genes" have been identified that form a feedback loop of gene transcription and translation. The core genetic clockwork generates circadian rhythms in cells throughout the body. Polymorphisms in both core clock genes and interacting genes contribute to individual differences in the expression and properties of circadian rhythms. The circadian clock profoundly influences the patterns of gene expression and cellular functions, providing a mechanistic basis for the impact of the genetic circadian system on normal physiological processes as well as the development of diseases.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.ncl.2019.05.002

Cites

128 of 128 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Vitaterna, M. H., Shimomura, K., & Jiang, P.
Affiliations
Northwestern University (US)
Corresponding author
Vitaterna, Martha Hotz
Venue
Neurologic Clinics
Publisher
Elsevier BV
Published
2019-08
Volume
37
Issue
3
Pages
487-504
ISSN
0733-8619 (ISSN-L)
OpenAlex
W2947961383
Cited by
36
References
128
Citations by year
2026: 3 · 2025: 8 · 2024: 15 · 2023: 3 · 2022: 4 · 2021: 3
FWCI
0.21
Type
journal article
Language
en
Open access
Locations
  • Neurologic Clinics (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
NIH (PO1 AG 11412)
Topics
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
Keywords
circadian rhythm, clock genes, circadian clock, genetic polymorphism, gene expression rhythms
MeSH terms
Animals, Circadian Rhythm, Humans, Circadian Clocks

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review