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A Novel Clathrin Adaptor Complex Mediates Basolateral Targeting in Polarized Epithelial Cells

Fölsch, Heike, Ohno, Hiroshi, Bonifacino, Juan S, Mellman, Ira·1999·Cell

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  • The proteins involved in decoding basolateral sorting signals have been the widely expressed AP4 complex and the clathrin adaptor complex AP1B, both acting predominantly upon Y-dependent motifs.

    “So far, the proteins involved in decoding basolateral sorting signals have been the widely expressed AP4 complex (Simmen et al., 2002) and the clathrin adaptor complexes AP1B complex specifically expressed by certain epithelial cells (Folsch et al., 1999; Ohno et al., 1999; Gan et al., 2002), both acting predominantly upon Y-dependent motifs.”

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Metadata

Authors
Fölsch, H., Ohno, H., Bonifacino, J. S., & Mellman, I.
Venue
Cell
Publisher
Elsevier BV
Published
1999-10
Volume
99
Issue
2
Pages
189-198
ISSN
0092-8674
Cited by
467
References
1
Language
en
Funders
  • Deutsche Forschungsgemeinschaft
  • Ministry of Education, Culture, Sports, Science and Technology
  • National Institutes of Health (GM-29765)

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