Cited by 1,073Asthma and respiratory diseasesChronic Obstructive Pulmonary Disease (COPD) ResearchRespiratory and Cough-Related Research

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After asthma: redefining airways diseases

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Pavord, Ian D, Beasley, Richard, Agusti, Alvar, Anderson, Gary P, Bel, Elisabeth, Brusselle, Guy, Cullinan, Paul, Custovic, Adnan, Ducharme, Francine M, Fahy, John V, Frey, Urs, Gibson, Peter, Heaney, Liam G, Holt, Patrick G, Humbert, Marc, Lloyd, Clare M, Marks, Guy, Martinez, Fernando D, Sly, Peter D, von Mutius, Erika, Wenzel, Sally, Zar, Heather J, Bush, Andy·2018·The Lancet

DOI 10.1016/s0140-6736(17)30879-6

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Abstract

Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observed in the past 10 years, despite escalating treatment costs. New assessment techniques are not being adopted and new drug discovery has progressed more slowly than in other specialties.

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Authors: Pavord, I. D., Beasley, R., Agusti, A., Anderson, G. P., Bel, E., Brusselle, G., Cullinan, P., Custovic, A., Ducharme, F. M., Fahy, J. V., Frey, U., Gibson, P., Heaney, L. G., Holt, P. G., Humbert, M., Lloyd, C. M., Marks, G., Martinez, F. D., Sly, P. D., von Mutius, E., Wenzel, S., Zar, H. J., & Bush, A.
Affiliations: University of Oxford (GB)
Medical Research Institute of New Zealand (NZ)
The University of Melbourne (AU)
Amsterdam UMC Location University of Amsterdam (NL)
Ghent University Hospital (BE)
Imperial College London (GB)
Université de Montréal (CA)
University of California, San Francisco (US)
University of Basel (CH)
John Hunter Hospital (AU)
Queen's University Belfast (GB)
The Kids Research Institute Australia (AU)
Université Paris-Sud (FR)
UNSW Sydney (AU)
Children's Health Queensland Hospital and Health Service (AU)
University of Pittsburgh (US)
University of Cape Town (ZA)
Corresponding author: Pavord, Ian D
ORCID: Pavord, Ian D
Beasley, Richard
Anderson, Gary P
Bel, Elisabeth
Brusselle, Guy
Cullinan, Paul
Ducharme, Francine M
Fahy, John V
Frey, Urs
Gibson, Peter
Heaney, Liam G
Holt, Patrick G
Humbert, Marc
Lloyd, Clare M
Marks, Guy
Sly, Peter D
Wenzel, Sally
Zar, Heather J
Venue: The Lancet
Publisher: Elsevier BV
Published: 2018-01
Volume: 391
Issue: 10118
Pages: 350-400
ISSN: 0099-5355 (ISSN-L)
0140-6736
DOI: 10.1016/s0140-6736(17)30879-6
OpenAlex: W2754586014
Cited by: 1,073
References: 336
Citations by year: 2026: 88 · 2025: 95 · 2024: 98 · 2023: 126 · 2022: 115 · 2021: 138 · 2020: 166 · 2019: 118 · 2018: 116
FWCI: 13.86
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: public-domain
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Lancet (publishedVersion, public-domain)
PubMed (publishedVersion)
Ghent University Academic Bibliography (Ghent University) (publishedVersion)
Pure Amsterdam UMC (publishedVersion)
EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
edoc (University of Basel) (acceptedVersion)
UWA Profiles and Research Repository (UWA) (submittedVersion)
Data Archiving and Networked Services (DANS) (submittedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
HAL (submittedVersion)
Ghent University Academic Bibliography (Ghent University) (submittedVersion)
Deakin Research Online (Deakin University) (submittedVersion)
Figshare (submittedVersion)
Research Portal (Queen's University Belfast) (submittedVersion)
Spiral (Imperial College London) (submittedVersion, cc-by-nc-nd)
NOVA (University of Newcastle Australia) (submittedVersion)
edoc (University of Basel)
Funders: National Institute of Allergy and Infectious Diseases
Medical Research Council
Topics: Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory and Cough-Related Research
Keywords: asthma, airway disease, asthma outcomes, asthma mortality, hospitalization, treatment costs, drug discovery, health care costs
MeSH terms: Asthma, United Kingdom, Humans, Public Health, Respiration Disorders

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