Cited by 229Posttraumatic Stress Disorder ResearchAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPsychoanalysis and Psychopathology Research

Psychophysiological assessment: clinical applications for PTSD

Orr, Scott P, Roth, Walton T·2000·Journal of Affective Disorders

Abstract

Descriptions of anxiety disorders clearly recognize the physiological features of anxiety, yet in most clinical practice and research there is little actual use of physiological measurement. This is unfortunate because a potentially important source of information is thereby unavailable and is likely to result in judgements about emotional experience that are less accurate, complete, and reliable than those that include physiological information. The neglect of physiological measures may result from a variety of concerns regarding test attributes such as reliability, validity, utility, and complexity. Promising results from studies of posttraumatic stress disorder (PTSD) demonstrate that physiological assessment can provide valuable clinical and theoretical insight. Numerous studies have now shown that heightened physiological reactivity to trauma-related cues is highly indicative of a diagnosis of PTSD. Physiological tests have achieved some success in predicting the development and persistence of PTSD, and in predicting and assessing treatment response. Studies of the startle response, aversive conditioning, and brain potentials during cognitive processing have identified several potentially important differences between PTSD patients and controls. This paper provides an overview of psychophysiological findings in PTSD and considers potential clinical applications of psychophysiological assessment for this disorder.

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Crossref · 10.1016/s0165-0327(00)00340-2

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Authors
Orr, S. P., & Roth, W. T.
Affiliations
  • United States Department of Veterans Affairs (US)
  • VA Palo Alto Health Care System (US)
Corresponding author
Orr, Scott P
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2000-12
Volume
61
Issue
3
Pages
225-240
ISSN
0165-0327 (ISSN-L)
OpenAlex
W1985444832
Cited by
229
References
8
Citations by year
2026: 2 · 2025: 2 · 2024: 6 · 2023: 5 · 2022: 5 · 2021: 6 · 2020: 7 · 2019: 9 · 2018: 10 · 2017: 5 · 2016: 15 · 2015: 9 · 2014: 17 · 2013: 8 · 2012: 16
FWCI
1.73
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
Keywords
post-traumatic stress disorder, psychophysiological assessment, startle response, aversive conditioning, brain potentials, treatment response prediction, PTSD diagnosis, anxiety disorders
MeSH terms
Arousal, Combat Disorders, Cues, Humans, Psychophysiology, Stress Disorders, Post-Traumatic

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