CoChat
Sign Up
Cited by 96Treatment of Major DepressionAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesBipolar Disorder and Treatment

Relapse of major depression after complete and partial remission during a 2-year follow-up

Pintor, L·2003·Journal of Affective Disorders
DOI 10.1016/s0165-0327(01)00480-3
Open this paper in CoChat — free account

Abstract

Background Rates of remission and relapse were studied over more than 2 years in a sample of Spanish outpatients with DSM-III-R criteria of unipolar major depressive episodes.Methods Patients were treated following standardised pharmacological protocols at our centre. In the first visit, the structured clinical interview for DSM-III-R (SCID) was used. The following visits were held monthly. Phases of evolution were recorded using the Hamilton Depression Rating Scale (HDRS), applying the Frank criteria.Results A significantly greater proportion of relapse was observed in the partial remission group compared to the complete remission one. The rate of relapses for patients in complete remission was 15.18%, while for patients in partial remission was 67.61%. Partial remission was significantly associated with relapses.Limitations The short duration of the study and the decreasing sample size during the follow-up.Conclusions Partial remission after a depressive episode seems to be strongly associated with relapses. Moreover, this clinical factor could by itself fully predict short-term relapses.Clinical relevance The study shows the importance of reaching complete remission to decrease the rate of short-term relapses.

Integrity signals

Registry

Crossref · 10.1016/s0165-0327(01)00480-3

Cites

39 of 39 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Clinical variables such as number of previous episodes, severity of last episode, and family history of MDD are strong predictors of recurrence.

    “However, clinical variables such as number of previous episodes [7, 11, 19–22], severity of last episode [21, 22] and family history of MDD [21– 23] were strong predictors of recurrence.”

    From Predictors of recurrence of major depressive disorder (2020) · cites this paper as [21]

  • Other studies reported that family history significantly predicted recurrence.

    “Other studies [21–23] have reported that family history significantly predicted recurrence.”

    From Predictors of recurrence of major depressive disorder (2020) · cites this paper as [21]

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Related

Authors
Pintor, L.
Affiliations
Hospital Clínic de Barcelona (ES)
Corresponding author
Pintor, L
ORCID
Pintor, L
Venue
Journal of Affective Disorders
Publisher
Elsevier BV
Published
2003-02
Volume
73
Issue
3
Pages
237-244
ISSN
0165-0327 (ISSN-L)
DOI
10.1016/s0165-0327(01)00480-3
OpenAlex
W2007622737
Cited by
96
References
39
Citations by year
2024: 2 · 2023: 6 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 2 · 2017: 6 · 2016: 4 · 2015: 2 · 2014: 5 · 2013: 9 · 2012: 7
FWCI
2.33
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Affective Disorders (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
major depressive disorder, relapse, remission, partial remission, complete remission, outpatients, antidepressant treatment, recurrence prediction, long-term follow-up
MeSH terms
Adult, Aged, Antidepressive Agents, Combined Modality Therapy, Depressive Disorder, Major, Major Depressive Disorder, Dose-Response Relationship, Drug, Drug Therapy, Combination, Female, Follow-Up Studies, Humans, Male, Middle Aged, Psychotherapy, Recurrence, Treatment Outcome

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review