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The diverse functions of histone acetyltransferase complexes

Carrozza, Michael J., Utley, Rhea T., Workman, Jerry L., Côté, Jacques·2003·Trends in Genetics

Abstract

Although histone acetylation has historically been linked to transcription activation, recent studies indicate that this modification and the enzymes that catalyze it have much broader and diverse functions. Histone acetyltransferase complexes are involved in such diverse processes as transcription activation, gene silencing, DNA repair and cell-cycle progression. The high conservation of the acetyltransferase complexes and their functions illustrates their central role in cell growth and development.

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Metadata

Authors
Carrozza, M. J., Utley, R. T., Workman, J. L., & Côté, J.
Venue
Trends in Genetics
Publisher
Elsevier BV
Published
2003-06
Volume
19
Issue
6
Pages
321-329
ISSN
0168-9525
Cited by
487
References
4
Language
en

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