The DOI matches its Crossref record; 34 of the 35 references it cites were found in a registry or an index.
Microglia-specific localisation of a novel calcium binding protein, Iba1
Abstract
Recently it has been shown that mRNA of Iba1 (ionized calcium binding adaptor molecule 1), which was a novel calcium binding protein cDNA-cloned by our group, is specifically expressed in microglia in cultures of rat brain cells [Imai et al. Biophys. Biochem. Res. Commun., 224 (1996) 855-862]. In the present study, immunocytochemical and immunohistochemical examinations demonstrated that Iba1 protein is expressed in microglia alone both in cultured brain cells and in the brain, respectively. In a mixed cell culture of embryonic rat brain, immunocytochemically positive for Iba1 protein were the microglia but it was not detectable in neurons, astroglia, or oligodendroglia. Immunohistochemical staining of adult rat brain sections showed Iba1 protein to be specifically localised in ramified microglia. In addition, immunohistochemical staining and immunoblot analysis of activated microglia in the facial nucleus after facial nerve axotomy shows that expression of Iba1 protein was upregulated and peaked at 7 days. These results indicated that localisation of Iba1 protein is restricted to microglia both in vitro and in vivo, and that Iba1 protein plays a role in regulating the function of microglia, especially in the activated microglia.
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In the citing paper
“Since its first description in 1998 [3], IBA1 has been the most widely used marker for the immunohistochemical analysis of microglia.”
From Beyond Activation: Characterizing Microglial Functional Phenotypes (2021) · cites this paper as [3]
In the citing paper
“In contrast, the studies using cell counting for Iba1, which is expressed by all microglia,58, 77 assess the absolute number of microglia in the samples.”
From Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review (2018) · cites this paper as [58]
In the citing paper
“Iba1 is a pan-microglial marker whose expression increases with microglial activation,58, 77”
From Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review (2018) · cites this paper as [58]
In the citing paper
“Iba1 is a microglia specific marker, which expression increases with microglia activation and macrophage transformation [30]”
From APOE Genotype Differentially Modulates Effects of Anti-Aβ, Passive Immunization in APP Transgenic Mice (2017) · cites this paper as [30]
In the citing paper
“In AD mice, sustained microglial depletion with CSF1R inhibitor reduced plaque development.”
From Microglia in neurodegenerative diseases: mechanism and potential therapeutic targets (2023) · cites this paper as [32]
In the citing paper
“These markers have been extensively used to label or define microglia in various systems 24.”
From Efficient derivation of microglia-like cells from human pluripotent stem cells (2016) · cites this paper as [24]
Citations
Cites
Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4
LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961
McGeer, P. L., Itagaki, S., Boyes, B. E., & McGeer, E. G. (1988) · Neurology · doi:10.1212/wnl.38.8.1285 · Cited by 2,990
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
Lawson, L. J., Perry, V. H., Dri, P., & Gordon, S. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90229-w · Cited by 2,045
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain
Maddon, P. J., Dalgleish, A. G., McDougal, J. S., Clapham, P. R., Weiss, R. A., & Axel, R. (1986) · Cell · doi:10.1016/0092-8674(86)90590-8 · Cited by 2,003
Dijkstra, C. D., Döpp, E. A., Joling, P., & Kraal, G. (1985) · Springer eBooks · doi:10.1007/978-1-4613-2463-8_50 · Cited by 1,598
Perivascular microglial cells of the CNS are bone marrow-derived and present antigen in vivo
Hickey, W. F., & Kimura, H. (1988) · Science · doi:10.1126/science.3276004 · Cited by 1,466
Activation of microglial cells by β-amyloid protein and interferon-γ
Meda, L., Cassatella, M. A., Szendrei, G. I., Otvos, L., Baron, P., Villalba, M., Ferrari, D., & Rossi, F. (1995) · Nature · doi:10.1038/374647a0 · Cited by 1,314
Functional plasticity of microglia: A review
Streit, W. J., Graeber, M. B., & Kreutzberg, G. W. (1988) · Glia · doi:10.1002/glia.440010502 · Cited by 937
Perry, V. H., Hume, D. A., & Gordon, S. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90215-5 · Cited by 902
Research works printed but not linked: 2
- del Rio-Hortega, 1919, El tercer elemento de los centros nerviosos: I. La microglia en estados normal; II. Intervencio de la microglia en los processos patologicas; III. Naturaleza probable de la microglia, Bol. Soc. Espanola Biol., 9, 69
- Dolman, C.L., Microglia, in: R.L. Davis, D.M. Robertson (Eds.), Textbook of Neuropathology, Microglia, Williams and Wilkins, Baltimore, 1985, pp. 117–137.
Cited by
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Items 701–800 of 999
Labusek, N., Ghari, P., Mouloud, Y., Köster, C., Diesterbeck, E., Hadamitzky, M., Felderhoff‐Müser, U., Bendix, I., Giebel, B., & Herz, J. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02961-0 · Cited by 27
Obenaus, A., Huang, L., Smith, A., Favre, C. J., Nelson, G. A., & Kendall, E. J. (2008) · Radiation Research · doi:10.1667/rr1135.1 · Cited by 28
Lim, H.-W., Park, J.-I., More, S. V., Park, J., Kim, B.-W., Jeon, S., Yun, Y.-S., Park, E., Yoon, S., & Choi, D. (2015) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2015.01.004 · Cited by 27
Lee, C. H., Moon, S. M., Yoo, K., Choi, J. H., Park, O. K., Hwang, I. K., Sohn, Y., Moon, J. B., Cho, J. H., & Won, M. (2010) · Brain Research · doi:10.1016/j.brainres.2010.04.046 · Cited by 27
Cuadros, M. Á., Santos, A. M., Martín‐Oliva, D., Calvente, R., Tassi, M., Marín‐Teva, J. L., & Navascués, J. (2006) · Journal of Histochemistry & Cytochemistry · doi:10.1369/jhc.5a6832.2006 · Cited by 29
Kellom, M., Basselin, M., Keleshian, V. L., Chen, M., Rapoport, S. I., & Rao, J. S. (2012) · BMC Neuroscience · doi:10.1186/1471-2202-13-50 · Cited by 27
RetractedStrahan, J. A., Walker, W. H., Montgomery, T. R., & Forger, N. G. (2016) · Developmental Neurobiology · doi:10.1002/dneu.22457 · Cited by 26
Fujimura, M., Usuki, F., & Nakamura, A. (2018) · Toxicological Sciences · doi:10.1093/toxsci/kfy281 · Cited by 27
Qin, M., Wang, L., Wu, D., Williams, C. K., Xu, D., Kranz, E. O., Guo, Q., Guan, J., Vinters, H. V., Lee, Y., et al. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03132 · Cited by 28
Ahmed, S., Ma, N., Kawanokuchi, J., Matsuoka, K., Oikawa, S., Kobayashi, H., Hiraku, Y., & Murata, M. (2024) · Scientific Reports · doi:10.1038/s41598-024-57973-4 · Cited by 28
Annexin A3 as a Marker Protein for Microglia in the Central Nervous System of Rats
Zhang, Z., Li, Z., Ma, Z., Deng, M., Xing, M., Wu, J., Jiang, S., Wang, Q., Guo, Q., & Zou, W. (2021) · Neural Plasticity · doi:10.1155/2021/5575090 · Cited by 27
Möhle, L., Bascuñana, P., Brackhan, M., & Pahnke, J. (2021) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2021.109371 · Cited by 25
Advances in Visualizing Microglial Cells in Human Central Nervous System Tissue
Uff, C. E. G., Patel, K., Yeung, C., & Yip, P. K. (2022) · Biomolecules · doi:10.3390/biom12050603 · Cited by 27
Polyomavirus Wakes Up and Chooses Neurovirulence
Butic, A. B., Spencer, S. A., Shaheen, S. K., & Lukacher, A. E. (2023) · Viruses · doi:10.3390/v15102112 · Cited by 28
Shanmugam, A. K., Wang, J., Markand, S., Perry, R. L., Tawfik, A. M., Zorrilla, E. P., Ganapathy, V., & Smith, S. B. (2014) · Journal of Neurochemistry · doi:10.1111/jnc.13002 · Cited by 26
Persson, Å., Lindwall, C., Curtis, M. A., & Kuhn, H. G. (2010) · Neuroscience · doi:10.1016/j.neuroscience.2010.01.035 · Cited by 25
Assessment of Traumatic Brain Injury by Increased 64 Cu Uptake on 64 CuCl 2 PET/CT
Peng, F., Muzik, O., Gatson, J. W., Kernie, S. G., & Diaz-Arrastia, R. R. (2015) · Journal of Nuclear Medicine · doi:10.2967/jnumed.115.154575 · Cited by 26
Persisting Rickettsia typhi Causes Fatal Central Nervous System Inflammation
Osterloh, A., Papp, S., Moderzynski, K., Kuehl, S., Richardt, U., & Fleischer, B. (2016) · Infection and Immunity · doi:10.1128/iai.00034-16 · Cited by 30
Smith, B. L., Schmeltzer, S. N., Packard, B. A., Sah, R., & Herman, J. P. (2016) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2016.05.004 · Cited by 27
Kim, D., Kweon, K.-J., Kim, P., Kim, H., Kim, S. S., Sohn, N., Maeng, S., & Shin, J.-W. (2017) · Molecules · doi:10.3390/molecules22010122 · Cited by 26
Loss of IBA1-Expression in brains from individuals with obesity and hepatic dysfunction
Lier, J., Winter, K., Bleher, J., Grammig, J., Mueller, W. C., Streit, W., & Bechmann, I. (2019) · Brain Research · doi:10.1016/j.brainres.2019.01.006 · Cited by 26
Küst, B., Mantingh-Otter, I., Boddeke, E., & Copray, S. C. V. M. (2006) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2006.01.020 · Cited by 26
Irie, M., Itoh, J., Matsuzawa, A., Ikawa, M., Kiyonari, H., Kihara, M., Suzuki, T., Hiraoka, Y., Ishino, F., & Kaneko-Ishino, T. (2022) · Development · doi:10.1242/dev.200976 · Cited by 22
Chidambaram, H., & Chinnathambi, S. (2025) · Brain Network Disorders · doi:10.1016/j.bnd.2024.12.005 · Cited by 25
Distribution of microsomal prostaglandin E synthase‐1 in the mouse brain
Eskilsson, A., Tachikawa, M., Hosoya, K., & Blomqvist, A. G. (2014) · The Journal of Comparative Neurology · doi:10.1002/cne.23593 · Cited by 25
Baxter, V. K., Glowinski, R. M., Braxton, A. M., Potter, M. C., Slusher, B. S., & Griffin, D. E. (2017) · Virology · doi:10.1016/j.virol.2017.05.013 · Cited by 25
Pol, S. U., Schweser, F., Bertolino, N., Preda, M., Sveinsson, M., Sudyn, M. L., Babek, N., & Zivadinov, R. (2019) · Experimental Neurology · doi:10.1016/j.expneurol.2019.01.013 · Cited by 25
Riquier, A. J., & Sollars, S. I. (2019) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2019.100010 · Cited by 26
Mano, T., Murata, K., Kon, K., Shimizu, C., Ono, H., Shi, S., Yamada, R. G., Miyamichi, K., Susaki, E. A., Touhara, K., et al. (2021) · Cell Reports Methods · doi:10.1016/j.crmeth.2021.100038 · Cited by 31
Noffsinger, B., Witter, A. R., Sheybani, N., Xiao, A., Manigat, L. C., Zhong, Q., Taori, S., Harris, T. H., Bullock, T. N., Price, R. J., et al. (2021) · Journal of Neuro-Oncology · doi:10.1007/s11060-021-03822-7 · Cited by 25
Ma, K., Wu, H., Wang, S., & Li, B. (2021) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2021.112862 · Cited by 25
Yan, Q., Lv, J., Shen, X., Yang, J., Yang, J.-Z., Nie, R.-F., Lu, J., Huang, Y.-J., Wang, J.-Y., & Shen, X. (2022) · Acta Pharmacologica Sinica · doi:10.1038/s41401-021-00857-4 · Cited by 24
Nakamura, R., Nishimura, T., OCHIAI, T., Nakada, S., Nagatani, M., & Ogasawara, H. (2013) · Journal of Toxicologic Pathology · doi:10.1293/tox.26.55 · Cited by 25
Sosa, R. A., & Forsthuber, T. G. (2011) · Journal of Interferon & Cytokine Research · doi:10.1089/jir.2011.0052 · Cited by 28
Conner, K., Forbes, M. E., Lee, W. H., Lee, Y. W., & Riddle, D. R. (2011) · Radiation Research · doi:10.1667/rr2560.1 · Cited by 26
Restoration of metabolic inflammation-related ghrelin resistance by weight loss
Naznin, F., Toshinai, K., Waise, T. M. Z., Okada, T., Sakoda, H., & Nakazato, M. (2017) · Journal of Molecular Endocrinology · doi:10.1530/jme-17-0192 · Cited by 24
Ahmadpour, D., & Grange‐Messent, V. (2020) · Neuroendocrinology · doi:10.1159/000509218 · Cited by 22
Morales‐Ropero, J. M., Arroyo‐Urea, S., Neubrand, V. E., Martín‐Oliva, D., Marín‐Teva, J. L., Cuadros, M. Á., Vangheluwe, P., Navascués, J., Mata, A. M., & Sepúlveda, M. R. (2020) · Glia · doi:10.1002/glia.23931 · Cited by 23
Minocycline fails to treat chronic traumatic brain injury-induced impulsivity and attention deficits
Pechacek, K. M., Reck, A. M., Frankot, M. A., & Haar, C. V. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113924 · Cited by 24
Naeem, A. G., El‐Naga, R. N., & Michel, H. E. (2022) · Inflammopharmacology · doi:10.1007/s10787-022-01045-4 · Cited by 25
Lin, Y., Li, C., Wang, W., Li, J., Huang, C., Zheng, X., Liu, Z., Song, X., Chen, Y., Gao, J., et al. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1115348 · Cited by 23
Reverte, I., Marchetti, C., Pezza, S., Zenoni, S. F., Scaringi, G., Ferrucci, L., D’Ottavio, G., Pignataro, A., Andolina, D., Raspa, M., et al. (2023) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2023.11.007 · Cited by 22
Hundeshagen, G., Szameit, K., Thieme, H., Finkensieper, M., Angelov, D. N., Guntinas‐Lichius, O., & Irintchev, A. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.06.019 · Cited by 24
Expression of Iba1 protein in microglial cells of zitter mutant rat
Kadowaki, T., Nakadate, K., Sakakibara, S., Hirata, K., & Ueda, S. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2006.07.079 · Cited by 24
Drábek, T., Tisherman, S. A., Beuke, L., Stezoski, J. P., Janesko‐Feldman, K. L., Lahoud-Rahme, M., & Kochanek, P. M. (2009) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e3181b0511e · Cited by 24
Niemann-Pick Type C1 deficiency in microglia does not cause neuron death in vitro
Peake, K., Campenot, R. B., Vance, D. E., & Vance, J. E. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2011.06.003 · Cited by 24
Raslan, A., Ernst, P., Werle, M., Thieme, H., Szameit, K., Finkensieper, M., Guntinas‐Lichius, O., & Irintchev, A. (2013) · Brain Structure and Function · doi:10.1007/s00429-013-0542-6 · Cited by 24
Glial responses after chorda tympani nerve injury
Bartel, D. L. (2012) · The Journal of Comparative Neurology · doi:10.1002/cne.23069 · Cited by 24
Brecht, S., Waetzig, V., Hidding, U., Hanisch, U., Walther, M. R., Herdegen, T., & Neiss, W. F. (2009) · The Anatomical Record · doi:10.1002/ar.20994 · Cited by 24
Microglia activation during neuroregeneration in the adult vertebrate brain
Kirkham, M., Berg, D. A., & Simon, A. (2011) · Neuroscience Letters · doi:10.1016/j.neulet.2011.04.007 · Cited by 24
Flow cytometric characterization of microglia in the offspring of PolyI:C treated mice
Manitz, M. P., Plümper, J., Demir, S., Ahrens, M., Eßlinger, M., Wachholz, S., Eisenacher, M., Juckel, G., & Friebe, A. (2016) · Brain Research · doi:10.1016/j.brainres.2016.02.004 · Cited by 25
Mao, Q., Wang, D., Li, Y., Kohler, M., Wilson, J., Parton, Z., Shmaltsuyeva, B., Gursel, D. B., Rademakers, R., Weıntraub, S., et al. (2017) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlx085 · Cited by 24
Ren, Z., Wang, X., Xu, M., Frank, J. A., & Luo, J. (2018) · Alcohol · doi:10.1016/j.alcohol.2018.12.002 · Cited by 25
Tanaka, T., Masubuchi, Y., Okada, R., Nakajima, K., Nakamura, K., Masuda, S., Nakahara, J., Maronpot, R. R., Yoshida, T., Koyanagi, M., et al. (2019) · The Journal of Toxicological Sciences · doi:10.2131/jts.44.357 · Cited by 24
Self-citationWasseff, S. K., & Scherer, S. S. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.05.018 · Cited by 24
Eleore, L., Vassias, I., Vidal, P. P., & de Waele, C. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.06.026 · Cited by 24
Okere, C. O., & Kaba, H. (2000) · Brain Research · doi:10.1016/s0006-8993(00)02656-1 · Cited by 24
Dynamic expression of Dab2 in the mouse embryonic central nervous system
Cheung, K.-K., Mok, S. C., Rezaie, P., & Chan, W. Y. (2008) · BMC Developmental Biology · doi:10.1186/1471-213x-8-76 · Cited by 23
Pathophysiological dual action of adiponectin after transient focal ischemia in mouse brain
Yatomi, K., Miyamoto, N., Komine‐Kobayashi, M., Liu, M., Oishi, H., Arai, H., Hattori, N., & Urabe, T. (2009) · Brain Research · doi:10.1016/j.brainres.2009.08.039 · Cited by 22
Songarj, P., Luh, C., Staib-Lasarzik, I., Engelhard, K., Moosmann, B., & Thal, S. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2014.10.037 · Cited by 19
Rayner, C. L., Gole, G. A., Bottle, S. E., & Barnett, N. L. (2014) · Experimental Eye Research · doi:10.1016/j.exer.2014.10.013 · Cited by 23
Bertling, F., Bendix, I., Drommelschmidt, K., Wisniewski, H., Felderhoff‐Mueser, U., Keller, M., & Prager, S. (2016) · Experimental Neurology · doi:10.1016/j.expneurol.2016.03.005 · Cited by 23
Luca, S. D., Ziko, I., Dhuna, K., Sominsky, L., Tolcos, M., Stokes, L., & Spencer, S. (2017) · Journal of neuroendocrinology · doi:10.1111/jne.12540 · Cited by 21
Siemsen, B. M., Landin, J. D., McFaddin, J. A., Hooker, K. N., Chandler, L. J., & Scofield, M. D. (2020) · Journal of Neuroscience Research · doi:10.1002/jnr.24683 · Cited by 26
Cheng, W., Sun, Y., Wu, Q., Ooi, K., Feng, Y., Xia, C., & Zhu, D. (2021) · Neuroscience Bulletin · doi:10.1007/s12264-021-00641-8 · Cited by 23
Taoro‐González, L., Pereda, D., Valdés‐Baizabal, C., González‐Gómez, M., Pérez, J. A., Mesa-Herrera, F., Canerina‐Amaro, A., Perez-Gonzalez, H., Rodríguez, C., Díaz, M. L., et al. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23137430 · Cited by 26
Neuroinflammation Induced by Intracerebroventricular Injection of Microbial Neuraminidase
Granados‐Durán, P., López-Ávalos, M. D., Grondona, J. M., Gómez-Roldán, M. D. C., Cifuentes, M., Pérez‐Martín, M., Álvarez, M., de Fonseca, F. R., & Fernández‐Llebrez, P. (2015) · Frontiers in Medicine · doi:10.3389/fmed.2015.00014 · Cited by 24
Statistical parametric mapping of immunopositive cell density
Wada, M., Yoshimi, K., Higo, N., Ren, Y., Mochizuki, H., Mizuno, Y., & Kitazawa, S. (2006) · Neuroscience Research · doi:10.1016/j.neures.2006.05.013 · Cited by 23
Sinha, S., Avcu, P., Spiegler, K. M., Komaravolu, S., Kim, K., Cominski, T. P., Servatius, R. J., & Pang, K. C. H. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.01.006 · Cited by 26
Hippocampal plasticity after a vagus nerve injury in the rat.
(2012) · PubMed Central · doi:10.3969/j.issn.1673-5374.2012.14.003 · Cited by 23
Noble, M., Scott‐Hewitt, N., & Folts, C. J. (2018) · Neural Regeneration Research · doi:10.4103/1673-5374.228712 · Cited by 23
Seminotti, B., Zanatta, Â., Ribeiro, R. T., da Rosa, M. S., Wyse, Â. T. D. S., Leipnitz, G., & Wajner, M. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1275-6 · Cited by 25
Long-term in vivo time-lapse imaging of synapse development and plasticity in the cerebellum
Nishiyama, N., Colonna, J., Shen, E., Carrillo, J., & Nishiyama, H. (2013) · Journal of Neurophysiology · doi:10.1152/jn.00588.2013 · Cited by 25
Microglia across evolution: from conserved origins to functional divergence
Shimizu, T., & Prinz, M. (2025) · Cellular and Molecular Immunology · doi:10.1038/s41423-025-01368-6 · Cited by 28
Gilman, T. L., Mitchell, N. C., Daws, L. C., & Toney, G. M. (2018) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyy099 · Cited by 22
Fesharaki‐Zadeh, A., Miyauchi, J. T., Laurent-Ariot, K. S., Tsirka, S. E., & Bergold, P. J. (2020) · ASN NEURO · doi:10.1177/1759091420979567 · Cited by 23
Li, S. H., Colson, T. L., Abd‐Elrahman, K. S., & Ferguson, S. S. G. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.801757 · Cited by 23
iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotype
Sullivan, M. A., Lane, S. D., McKenzie, A. D. J., Ball, S. R., Sunde, M., Neely, G. G., Moreno, C. L., Maximova, A., Werry, E. L., & Kassiou, M. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02951-2 · Cited by 23
Expressions of Iba1 and galectin-3 (Gal-3) in thioacetamide (TAA)-induced acute rat liver lesions
Wijesundera, K. K., Juniantito, V., Golbar, H. M., Fujisawa, K., Tanaka, M., Ichikawa, C., Izawa, T., Kuwamura, M., & Yamate, J. (2012) · Experimental and Toxicologic Pathology · doi:10.1016/j.etp.2012.11.006 · Cited by 22
Fard, M. A., Ebrahimi, K. B., & Miller, N. R. (2013) · Brain Research · doi:10.1016/j.brainres.2013.07.053 · Cited by 22
Valous, N. A., Lahrmann, B., Zhou, W., Veltkamp, R. C., & Grabe, N. (2012) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2012.12.017 · Cited by 22
Connolly, N. P., Stokum, J. A., Schneider, C. S., Ozawa, T., Xu, S., Galisteo, R., Castellani, R. J., Kim, A. J., Simard, J. M., Winkles, J. A., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0174557 · Cited by 22
Maternal separation stress leads to resilience against neuropathic pain in adulthood
Genty, J., Nomigni, M. T., Anton, F., & Hanesch, U. (2017) · Neurobiology of Stress · doi:10.1016/j.ynstr.2017.11.002 · Cited by 22
Nguyen-Ngo-Le, M.-A., Wen, Y., Ho, Y.-C., Kapupara, K., & Tsai, R. (2019) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.19-27129 · Cited by 22
Yang, Z., Bao, Y., Chen, W., & He, Y. (2019) · Neuropeptides · doi:10.1016/j.npep.2019.102002 · Cited by 22
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Saraswathy, S., Wu, G., & Rao, N. A. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-0221 · Cited by 22
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Metadata
- Authors
- Ito, D., Imai, Y., Ohsawa, K., Nakajima, K., Fukuuchi, Y., & Kohsaka, S.
- Affiliations
- Keio University (JP)
- National Institute of Neuroscience (JP)
- Corresponding author
- Kohsaka, Shinichi
- Venue
- Molecular Brain Research
- Publisher
- Elsevier BV
- Published
- 1998-06
- Volume
- 57
- Issue
- 1
- Pages
- 1-9
- ISSN
- 0169-328X (ISSN-L)
- OpenAlex
- W2053176712
- Cited by
- 1,476
- References
- 35
- Citations by year
- 2026: 56 · 2025: 82 · 2024: 77 · 2023: 88 · 2022: 92 · 2021: 95 · 2020: 85 · 2019: 103 · 2018: 82 · 2017: 78 · 2016: 70 · 2015: 52 · 2014: 78 · 2013: 55 · 2012: 57
- FWCI
- 5.80
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Brain Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Neurology › Neuroinflammation and Neurodegeneration Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Neurology › Neurological Disease Mechanisms and Treatments
- Keywords
- Iba1, calcium-binding proteins, microglia, microglial activation, facial nerve axotomy, facial nucleus, ramified microglia, rat brain
- MeSH terms
- Animals, Brain, Calcium-Binding Proteins, Cells, Cultured, Facial Nerve, Fluorescent Antibody Technique, Microfilament Proteins, Motor Neurons, Rats, Wistar, Microglia, Axotomy, Rats
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