Age-related impairment in long-term potentiation in hippocampus: a role for the cytokine, interleukin-1β?

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

Morris, R. G. M., Anderson, E., Lynch, G. S., & Baudry, M. (1986) · Nature · doi:10.1038/319774a0 · Cited by 3,640

Reactive Oxygen Species and the Central Nervous System

Halliwell, B. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb10990.x · Cited by 2,947

Excitatory amino acids in synaptic transmission in the Schaffer collateral-commissural pathway of the rat hippocampus

Collingridge, G. L., Kehl, S. J., & McLennan, H. (1983) · The Journal of Physiology · doi:10.1113/jphysiol.1983.sp014478 · Cited by 2,413

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease.

Griffin, W. S., Stanley, L. C., Ling, C., White, L., MacLeod, V, Perrot, L. J., White, C. L., & Araoz, C. (1989) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.86.19.7611 · Cited by 1,777

Fear conditioning induces associative long-term potentiation in the amygdala

Rogan, M. T., Stäubli, U. V., & LeDoux, J. E. (1997) · Nature · doi:10.1038/37601 · Cited by 1,310

Regulation of synaptic responses to high-frequency stimulation and LTP by neurotrophins in the hippocampus

Figurov, A., Pozzo-Miller, L. D., Olafsson, P., Wang, T., & Lu, B. (1996) · Nature · doi:10.1038/381706a0 · Cited by 1,106

An essential role for postsynaptic calmodulin and protein kinase activity in long-term potentiation

Malenka, R. C., Kauer, J. A., Perkel, D. J., Mauk, M. D., Kelly, P. T., Nicoll, R. A., & Waxham, M. N. (1989) · Nature · doi:10.1038/340554a0 · Cited by 1,025

Interleukin-1β (IL-1β) and tumour necrosis factor (TNF) inhibit long-term potentiation in the rat dentate gyrus in vitro

Cunningham, A. J., Murray, C. A., O'Neill, L. A. J., Lynch, M. A., & O'Connor, J. J. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(95)12252-4 · Cited by 433

Immune modulation of learning, memory, neural plasticity and neurogenesis

Yirmiya, R., & Goshen, I. (2011) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2010.10.015 · Cited by 1,483

Evidence for a cytokine model of cognitive function

McAfoose, J., & Baune, B. T. (2009) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2008.10.005 · Cited by 760

Does neuroinflammation fan the flame in neurodegenerative diseases?

Frank-Cannon, T. C., Alto, L. T., McAlpine, F. E., & Tansey, M. G. (2009) · Molecular Neurodegeneration · doi:10.1186/1750-1326-4-47 · Cited by 751

Cytokines and cognition–the case for a head-to-toe inflammatory paradigm.

Wilson, C. J., Finch, C. E., & Cohen, H. J. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50619.x · Cited by 637

Pro-inflammatory cytokines and their effects in the dentate gyrus

Pickering, M., & O’Connor, J. J. (2007) · Progress in Brain Research · doi:10.1016/s0079-6123(07)63020-9 · Cited by 217

The Inhibitory Effect of Interleukin-1β on Long-Term Potentiation Is Coupled with Increased Activity of Stress-Activated Protein Kinases

Vereker, E., O'Donnell, E., & Lynch, M. A. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-18-06811.2000 · Cited by 214

BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1β administration

Barrientos, R. M., Sprunger, D. B., Campeau, S., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2004) · Journal of Neuroimmunology · doi:10.1016/j.jneuroim.2004.06.009 · Cited by 192

Polyunsaturated fatty acids, neuroinflammation and well being

Layé, S. (2010) · Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) · doi:10.1016/j.plefa.2010.02.006 · Cited by 167

Diets enriched in foods with high antioxidant activity reverse age-induced decreases in cerebellar β-adrenergic function and increases in proinflammatory cytokines

Gemma, C., Mesches, M. H., Sepesi, B., Choo, K., Holmes, D. B., & Bickford, P. C. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-14-06114.2002 · Cited by 143

Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus

Prieto, G. A., Snigdha, S., Baglietto-Vargas, D., Smith, E. D., Berchtold, N. C., Tong, L., Ajami, D., LaFerla, F. M., Rebek, J., & Cotman, C. W. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1514486112 · Cited by 126

Neuroinflammatory changes negatively impact on LTP: A focus on IL-1β

Lynch, M. A. (2015) · Brain Research · doi:10.1016/j.brainres.2014.08.040 · Cited by 115

Improvement of memory for context by inhibition of caspase‐1 in aged rats

Gemma, C., Fister, M., Hudson, C., & Bickford, P. C. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04334.x · Cited by 74

Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer’s disease: Alleviation by pantethine

van Gijsel-Bonnello, M., Baranger, K., Benech, P., Rivera, S., Khrestchatisky, M., de Reggi, M., & Gharib, B. (2017) · PLOS ONE · doi:10.1371/journal.pone.0175369 · Cited by 63

Augmenting saturated LTP by broadly spaced episodes of theta-burst stimulation in hippocampal area CA1 of adult rats and mice

Cao, G., & Harris, K. M. (2014) · Journal of Neurophysiology · doi:10.1152/jn.00297.2014 · Cited by 41

Role of metabolic dysfunction in treatment resistance of major depressive disorder

Toups, M. S., & Trivedi, M. H. (2011) · Neuropsychiatry · doi:10.2217/npy.11.49 · Cited by 9