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Cited by 182Rheumatoid Arthritis Research and TherapiesMusculoskeletal pain and rehabilitationPsychological Treatments and Assessments

The DOI matches its Crossref record, with a small difference in title or year; 33 of the 33 references it cites were found in a registry or an index.

A blind, randomized, controlled trial of cognitive-behavioural intervention for patients with recent onset rheumatoid arthritis: preventing psychological and physical morbidity

Sharpe, L., Sensky, T., Timberlake, N., Ryan, B., Brewin, C. R., Allard, S.·2001·Pain
DOI 10.1016/s0304-3959(00)00379-1
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Abstract

This study examined the efficacy of a cognitive and behavioural intervention (CBT) for patients with recent onset, seropositive rheumatoid arthritis. Fifty-three participants with a diagnosis of classical or definite rheumatoid arthritis, who were seropositive and had less than 2 years of disease history were recruited into the trial. All participants received routine medical management during the study, although half were randomly allocated to receive an adjunctive psychological intervention. All pre- and post-treatment assessments were conducted blind to the allocation. Analyses were conducted of treatment completers and also by intention-to-treat. Significant differences were found between the groups at both post-treatment and 6-month follow-up in depressive symptoms. While the CBT group showed a reduction in depressive symptoms, the same symptoms increased in the Standard group. At outcome but not follow-up, the CBT group also showed reduction in C-reactive protein levels. However, the CBT group did show significant improvement in joint involvement at 6-month follow-up compared with the Standard group, indicating physical improvements above those achieved with standard care. These results indicate that cognitive-behavioural intervention offered as an adjunct to standard clinical management early in the course of RA is efficacious in producing reductions in both psychological and physical morbidity

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Crossref · 10.1016/s0304-3959(00)00379-1

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Research works printed but not linked: 1

  1. Corbett, 1993, Factors predicting death, survival and functional outcome in a prospective study of early rheumatoid arthritis over fifteen years., Br J Rheumatol, 33, 754

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Metadata

Authors
Sharpe, L., Sensky, T., Timberlake, N., Ryan, B., Brewin, C. R., & Allard, S.
Affiliations
  • University of London (GB)
  • West Middlesex University Hospital (GB)
Corresponding author
Sharpe, L.
ORCID
Venue
Pain
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2001-01
Volume
89
Issue
2
Pages
275-283
ISSN
0304-3959 (ISSN-L)
DOI
10.1016/s0304-3959(00)00379-1
OpenAlex
W2079988544
Cited by
182
References
32
Citations by year
2026: 1 · 2025: 7 · 2024: 3 · 2023: 3 · 2022: 3 · 2021: 2 · 2020: 4 · 2019: 9 · 2018: 3 · 2017: 4 · 2016: 7 · 2015: 6 · 2014: 7 · 2013: 7 · 2012: 10
FWCI
5.51
Type
journal article
Language
en
Open access
closed
Locations
  • Pain (publishedVersion)
  • PubMed (publishedVersion)
  • UCL Discovery (University College London) (submittedVersion)
Topics
  • Health Sciences › Medicine › Rheumatology › Rheumatoid Arthritis Research and Therapies
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
  • Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Assessments
Keywords
cognitive behavioral therapy, rheumatoid arthritis, early rheumatoid arthritis, seropositive rheumatoid arthritis, depressive symptoms, C-reactive protein, joint involvement, physical morbidity, psychological morbidity
MeSH terms
Adaptation, Psychological, Aged, Anxiety, Arthritis, Rheumatoid, Behavior Therapy, Depression, Double-Blind Method, Female, Humans, Male, Middle Aged, Pain Measurement, Psychiatric Status Rating Scales, Surveys and Questionnaires, Cognitive Behavioral Therapy, Disease Progression

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