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Cited by 136Musculoskeletal pain and rehabilitationAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPain Management and Treatment

Is there a potential role for attention bias modification in pain patients? Results of 2 randomised, controlled trials.

Sharpe, Louise, Ianiello, Melissa, Dear, Blake F., Perry, Kathryn Nicholson, Refshauge, Kathryn, Nicholas, Michael K.·2012·Pain
DOI 10.1016/j.pain.2011.12.014
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Abstract

Potential applications of attention bias modification (ABM) for acute and chronic pain patients are investigated. In study 1, 54 acute back pain patients (46 of whom completed the study) were recruited at their initial physiotherapy session and randomised to receive 1 session of ABM or placebo. Patients were followed up 3 months later. Participants who were randomised to receive ABM reported less average (P=0.001) and current pain (P=0.008) and experienced pain for fewer days (P=0.01) than those who received placebo. In study 2, 34 chronic pain patients were recruited and randomly assigned to receive either 4 sessions of ABM (n=22) or placebo (n=12), followed by 8 sessions of cognitive behavioural treatment (CBT). After ABM, there was a significant group-by-time effect for disability. By 6-month follow-up, differences had emerged between the 2 training groups, such that the ABM group had shown greater reductions in anxiety sensitivity and disability than the placebo group. Although the results of these studies show that there is potential in the application of ABM to pain conditions, the mechanisms of treatment could not be established. Neither group showed an initial bias towards the word stimuli or a training effect, and only in the acute pain group were changes in biases related to outcome. Nonetheless, the fact that 2 independent samples showed a positive effect of ABM on clinical outcomes suggests that ABM is worthy of future study as an intervention for pain patients.

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  • The dissociative PTSD pattern involves changes in connectivity and activation of the right anterior insula.

    “changes in connectivity and activation of the right anterior insula,55,127,128”

    From Fear and the Defense Cascade (2015) · cites this paper as [127]

  • Initial positive results with attention bias modification have been reported in chronic pain.

    “Initial positive results with this strategy have been reported in chronic pain [14] and in psychopathology [8].”

    From Attentional bias and chronic pain: Where to go from here? (2014) · cites this paper as [14]

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Authors
Sharpe, L., Ianiello, M., Dear, B. F., Perry, K. N., Refshauge, K., & Nicholas, M. K.
Affiliations
  • The University of Sydney (AU)
  • Macquarie University (AU)
  • Western Sydney University (AU)
Corresponding author
Sharpe, Louise
ORCID
Venue
Pain
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2012-03
Volume
153
Issue
3
Pages
722-731
ISSN
0304-3959 (ISSN-L)
DOI
10.1016/j.pain.2011.12.014
OpenAlex
W2029321389
Cited by
136
References
50
Citations by year
2026: 2 · 2025: 7 · 2024: 8 · 2023: 8 · 2022: 6 · 2021: 8 · 2020: 9 · 2019: 7 · 2018: 11 · 2017: 15 · 2016: 11 · 2015: 10 · 2014: 14 · 2013: 12 · 2012: 5
FWCI
9.64
Type
journal article
Language
en
Open access
closed
Locations
  • Pain (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
Keywords
attentional bias modification, acute low back pain, chronic pain, pain-related anxiety, anxiety sensitivity, disability, cognitive behavioral therapy, placebo effect, pain intensity
MeSH terms
Adult, Analysis of Variance, Anxiety, Attention, Behavior Therapy, Depression, Disability Evaluation, Double-Blind Method, Female, Follow-Up Studies, Humans, Male, Middle Aged, Pain, Pain Measurement, Psychiatric Status Rating Scales, Surveys and Questionnaires, Retrospective Studies, Vocabulary, Cognitive Behavioral Therapy, Bias, Treatment Outcome, Young Adult

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