Cited by 226Dementia and Cognitive Impairment ResearchVisual perception and processing mechanismsRetinal Diseases and Treatments

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Visual dysfunction, neurodegenerative diseases, and aging

Jackson, Gregory R, Owsley, Cynthia·2003·Neurologic Clinics

DOI 10.1016/s0733-8619(02)00107-x

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Abstract

The four most common sight-threatening conditions in older adults in North America are cataract, ARM, glaucoma, and diabetic retinopathy. Even in their moderate stages, these conditions cause visual sensory impairments and reductions in health-related quality of life, including difficulties in daily tasks and psychosocial problems. Many older adults are free from these conditions, yet still experience a variety of visual perceptual problems resulting from aging-related changes in the optics of the eye and degeneration of the visual neural pathways. These problems consist of impairments in visual acuity, contrast sensitivity, color discrimination, temporal sensitivity, motion perception, peripheral visual field sensitivity, and visual processing speed. PD causes a progressive loss of dopaminergic cells predominantly in the retina and possibly in other areas of the visual system. This retinal dopamine deficiency produces selective spatial-temporal abnormalities in retinal ganglion cell function, probably arising from altered receptive field organization in the PD retina. The cortical degeneration characteristics of AD, including neurofibrillary tangles and neuritic plaques, also are present in the visual cortical areas, especially in the visual association areas. The most prominent electrophysiologic change in AD is a delay in the P2 component of the flash VEP. Deficits in higher-order visual abilities typically are compromised in AD, including problems with visual attention, perceiving structure from motion, visual memory, visual learning, reading, and object and face perception. There have been reports of a visual variant of AD in which these types of visual problems are the initial and most prominent signs of the disease. Visual sensory impairments (e.g., contrast sensitivity or achromatopsia) also have been reported but are believed more reflective of cortical disturbances than of AD-associated optic neuropathy.

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The Effect of Intensive Treatment of Diabetes on the Development and Progression of Long-Term Complications in Insulin-Dependent Diabetes Mellitus
(1993) · New England Journal of Medicine · doi:10.1056/nejm199309303291401 · Cited by 24,667
Handbook of Sensory Physiology
Sanders, M. D. (1975) · British Journal of Ophthalmology · doi:10.1136/bjo.59.2.111-c · Cited by 7,166
Handbook of neuropsychology
Berti, A. (1992) · Neuropsychologia · doi:10.1016/0028-3932(92)90076-x · Cited by 4,190
Handbook of the Psychology of Aging
Schaie, K. W., Willis, S. L., Knight, B. G., & Park, D. C. (2016) · Elsevier eBooks · doi:10.1016/c2012-0-07221-3 · Cited by 3,440
A Randomized, Placebo-Controlled, Clinical Trial of High-Dose Supplementation With Vitamins C and E, Beta Carotene, and Zinc for Age-Related Macular Degeneration and Vision Loss: AREDS Report No. 8
(2001) · Archives of Ophthalmology · doi:10.1001/archopht.119.10.1417 · Cited by 3,285
Number of people with glaucoma worldwide.
Quigley, H. A. (1996) · British Journal of Ophthalmology · doi:10.1136/bjo.80.5.389 · Cited by 3,054
Development of the 25-list-item National Eye Institute Visual Function Questionnaire
Mangione, C. M. (2001) · Archives of Ophthalmology · doi:10.1001/archopht.119.7.1050 · Cited by 2,230
Prevalence of age-related maculopathy
Klein, R., Klein, B. E. K., & Linton, K. L. P. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)31871-8 · Cited by 1,845
Handbook of the Psychology of Aging
(1986) · Journal of Gerontology · doi:10.1093/geronj/41.2.296 · Cited by 1,557
Early Photocoagulation for Diabetic Retinopathy
* (1991) · Ophthalmology · doi:10.1016/s0161-6420(13)38011-7 · Cited by 1,548

Show all 192 references

Research works printed but not linked: 14

Owsley, 1990, A comparison of the Regan Low-Contrast Letter Charts and contrast sensitivity testing in older patients, Clin Vis Scie, 5, 325
Weale, 1975, Senile changes in vision acuity, Trans Ophthalmol Soc UK, 95, 36
Bodis-Wollner, 1980, Contrast sensitivity measurement in clinical diagnosis, vol. 1, 373
Haegerstrom-Portnoy, 1997, The SKILL card: an acuity test of reduced luminance and contrast, Invest Ophthalmol Vis Sci, 38, 207
Rubin, 1997, A comprehensive assessment of visual impairment in a population of older Americans, Invest Ophthalmol Vis Sci, 38, 557
Lakowski, 1958, Age and color vision, Adv Sci, 15, 231
Ohta, 1976, Colour perception changes with age, Mod Probl Ophthalmol, 17, 345
Iudice, 1980, The electroretinogram in Parkinson's disease. Research communications in psychology, Psychiatry and Behavior, 5, 283
Ellis, 1987, Electroretinographic abnormalities in idiopathic Parkinson's disease and the effect of levodopa administration, Cin Vis Sci, 1, 347
Murayama, 1989, Effects of L-Dopa on electroretinographic responses and pattern visual evoked potentials in juvenile Parkinsonism, Clin Vis Sci, 4, 265
Coben, 1977, The effect of aging and of dimming the stimulus upon the visual evoked response to reversing checks in man, Electroencephalogr Clin Neurophysiol, 43, 559
Gilmore, 1994, Motion perception and Alzheimer's disease, J Gerontol Psychol Sci, 49, P52, 10.1093/geronj/49.2.P52 · DOI
Damasio, 1985, Disorders of complex visual processing: agnosias, achromatopsias, Balint's syndrome and related difficulties of orientation and construction, vol. 26, 259
Wright, 1986, The flash and pattern VEP as a diagnostic indicator of dementia, Doc Ophthalmol, 62, 89, 10.1007/BF00140551 · DOI

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Vaux, L. M., Ni, R., Rizzo, M., Uc, E. Y., & Andersen, G. J. (2010) · Accident Analysis & Prevention · doi:10.1016/j.aap.2009.07.009 · Cited by 34
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Authors: Jackson, G. R., & Owsley, C.
Affiliations: University of Alabama at Birmingham (US)
Corresponding author: Jackson, Gregory R
ORCID: Owsley, Cynthia
Venue: Neurologic Clinics
Publisher: Elsevier BV
Published: 2003-08
Volume: 21
Issue: 3
Pages: 709-728
ISSN: 0733-8619 (ISSN-L)
DOI: 10.1016/s0733-8619(02)00107-x
OpenAlex: W2069089682
Cited by: 226
References: 192
Citations by year: 2026: 6 · 2025: 10 · 2024: 6 · 2023: 5 · 2022: 8 · 2021: 7 · 2020: 6 · 2019: 14 · 2018: 8 · 2017: 8 · 2016: 14 · 2015: 11 · 2014: 14 · 2013: 10 · 2012: 17
FWCI: 0.92
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Neurologic Clinics (publishedVersion)
PubMed (publishedVersion)
Funders: National Institute on Aging (R01 AG 04212, R01AG004212)
National Eye Institute (R21 EY 14071, R21EY014071)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
Keywords: visual dysfunction, aging, neurodegenerative diseases, Parkinson's disease, Alzheimer's disease, cataract, age-related macular degeneration, glaucoma, diabetic retinopathy, visual perception, contrast sensitivity, color vision, motion perception, visual field sensitivity, visual processing speed, retinal ganglion cells, dopamine deficiency, flash visual evoked potentials, visual attention, achromatopsia, optic neuropathy
MeSH terms: Age Factors, Aged, Aging, Alzheimer Disease, Humans, Parkinson Disease, Perceptual Disorders, Visual Acuity, Visual Perception, Neurodegenerative Diseases

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