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Cited by 632Advanced Scientific Research MethodsMicrobial Metabolic Engineering and BioproductionFood Nutrient Composition and Product Development

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Anupama, Ravindra, P.·2000·Biotechnology Advances
DOI 10.1016/s0734-9750(00)00045-8
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Abstract

The alarming rate of population growth has increased the demand for food production in third-world countries leading to a yawning gap in demand and supply. This has led to an increase in the number of hungry and chronically malnourished people. This situation has created a demand for the formulation of innovative and alternative proteinaceous food sources. Single cell protein (SCP) production is a major step in this direction. SCP is the protein extracted from cultivated microbial biomass. It can be used for protein supplementation of a staple diet by replacing costly conventional sources like soymeal and fishmeal to alleviate the problem of protein scarcity. Moreover, bioconversion of agricultural and industrial wastes to protein-rich food and fodder stocks has an additional benefit of making the final product cheaper. This would also offset the negative cost value of wastes used as substrate to yield SCP. Further, it would make food production less dependent upon land and relieve the pressure on agriculture. This article reviews diversified aspects of SCP as an alternative protein-supplementing source. Various potential strains and substrates that could be utilized for SCP production are described. Nutritive value and removal of nucleic acids and toxins from SCP as a protein-supplementing source are discussed. New processes need to be exploited to improve yield. In that direction the solid state fermentation (SSF) method and its advantages for SCP production are highlighted.

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Authors
Anupama, & Ravindra, P.
Affiliations
  • Jawaharlal Nehru Technological University, Hyderabad (IN)
  • Osmania University (IN)
Corresponding author
Ravindra, P.
Venue
Biotechnology Advances
Publisher
Elsevier BV
Published
2000-10
Volume
18
Issue
6
Pages
459-479
ISSN
0734-9750 (ISSN-L)
DOI
10.1016/s0734-9750(00)00045-8
OpenAlex
W1490594981
Cited by
632
References
0
Citations by year
2026: 33 · 2025: 39 · 2024: 52 · 2023: 57 · 2022: 62 · 2021: 24 · 2020: 37 · 2019: 37 · 2018: 42 · 2017: 36 · 2016: 29 · 2015: 14 · 2014: 24 · 2013: 20 · 2012: 26
FWCI
4.25
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Biotechnology Advances (publishedVersion)
  • PubMed (publishedVersion)
  • UMS Institutional Repository (Universiti Malaysia Sabah) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Advanced Scientific Research Methods
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Food Nutrient Composition and Product Development
Keywords
microbial protein, alternative protein sources, protein supplementation, malnutrition, food security, solid-state fermentation, microbial biomass, nucleic acid removal, toxin removal, nutritional value

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