Biotechnology—a sustainable alternative for chemical industry

Gavrilescu, Maria; Chisti, Yusuf

doi:10.1016/j.biotechadv.2005.03.004

Cited by 713Microbial Metabolic Engineering and BioproductionBiotechnology and Related FieldsChemistry and Chemical Engineering

Biotechnology—a sustainable alternative for chemical industry

Gavrilescu, Maria, Chisti, Yusuf·2005·Biotechnology Advances

DOI 10.1016/j.biotechadv.2005.03.004

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Abstract

This review outlines the current and emerging applications of biotechnology, particularly in the production and processing of chemicals, for sustainable development. Biotechnology is "the application of scientific and engineering principles to the processing of materials by biological agents". Some of the defining technologies of modern biotechnology include genetic engineering; culture of recombinant microorganisms, cells of animals and plants; metabolic engineering; hybridoma technology; bioelectronics; nanobiotechnology; protein engineering; transgenic animals and plants; tissue and organ engineering; immunological assays; genomics and proteomics; bioseparations and bioreactor technologies. Environmental and economic benefits that biotechnology can offer in manufacturing, monitoring and waste management are highlighted. These benefits include the following: greatly reduced dependence on nonrenewable fuels and other resources; reduced potential for pollution of industrial processes and products; ability to safely destroy accumulated pollutants for remediation of the environment; improved economics of production; and sustainable production of existing and novel products.

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Second generation biofuels involve terrestrial plants, especially food crops as feedstocks, a highly controversial issue, since biofuels production from food crops can only occur at the expense of their use as food and feed.
“Second generation biofuels involve terrestrial plants, especially food crops as feedstocks, a highly controversial issue, since biofuels production from food crops can only occur at the expense of their use as food and feed.”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [23]
Crop foods require arable land and large amounts of water, which makes their use for fuel production unsustainable and thus, incomputable as alternative liquid fuels.
“Additionally, crop foods require arable land and large amounts of water, which makes their use for fuel production unsustainable and thus, incomputable as alternative liquid fuels [23, 24].”
From The promising future of microalgae: Current status, challenges, and optimization of a sustainable and renewable industry for biofuels, feed, and other products (2018) · cites this paper as [23]

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Authors: Gavrilescu, M., & Chisti, Y.
Affiliations: Gheorghe Asachi Technical University of Iași (RO)
Corresponding author: Gavrilescu, Maria
ORCID: Gavrilescu, Maria
Venue: Biotechnology Advances
Publisher: Elsevier BV
Published: 2005-11
Volume: 23
Issue: 7-8
Pages: 471-499
ISSN: 0734-9750 (ISSN-L)
DOI: 10.1016/j.biotechadv.2005.03.004
OpenAlex: W2038175194
Cited by: 713
References: 159
Citations by year: 2026: 19 · 2025: 17 · 2024: 35 · 2023: 34 · 2022: 34 · 2021: 35 · 2020: 60 · 2019: 38 · 2018: 41 · 2017: 32 · 2016: 40 · 2015: 47 · 2014: 45 · 2013: 49 · 2012: 35
FWCI: 1.19
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biotechnology Advances (publishedVersion)
PubMed (publishedVersion)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Biotechnology and Related Fields
Physical Sciences › Environmental Science › Environmental Chemistry › Chemistry and Chemical Engineering
Keywords: biotechnology, sustainable chemical production, green chemistry, bioremediation, metabolic engineering, recombinant microorganisms, genetic engineering, nanobiotechnology, protein engineering, tissue engineering, bioseparation, bioreactors, waste management, pollution reduction, genetically modified organisms, hybridoma technology
MeSH terms: Biotechnology, Chemical Industry

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Biotechnology—a sustainable alternative for chemical industry

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