Lipofuscin: mechanisms of age-related accumulation and influence on cell function12 1Guest Editor: Rajindar S. Sohal 2This article is part of a series of reviews on “Oxidative Stress and Aging.” The full list of papers may be found on the homepage of the journal.

Aging: a theory based on free radical and radiation chemistry

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The Free Radical Theory of Aging Matures

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LYSOSOMAL STORAGE DISEASES

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The mitochondrial‐lysosomal axis theory of aging

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Lysosomal Storage Diseases

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The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

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Retinal age pigments generated by self-assembling lysosomotropic detergents

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Amyloid precursor protein, lipofuscin accumulation and expression of autophagy markers in aged bovine brain

Biase, D. D., Costagliola, A., Pagano, T. B., Piegari, G., Wojcik, S. P., Dziewíatkowski, J., Grieco, E., Raso, G. M., Russo, V., Papparella, S., et al. (2017) · BMC Veterinary Research · doi:10.1186/s12917-017-1028-1 · Cited by 19

Comparison of histologic findings in age-related macular degeneration with RPE flatmount images.

Zhang, Q., Chrenek, M. A., Bhatia, S. K., Rashid, A., Ferdous, S., Donaldson, K. J., Skelton, H. M., Wu, W., See, T. R. O., Jiang, Y., et al. (2019) · Europe PMC (PubMed Central) · Cited by 19

Lactoferrin ameliorates pathological cardiac hypertrophy related to mitochondrial quality control in aged mice

Huang, L., Chen, R., Liu, L., Zhou, Y., & Chen, Z. (2021) · Food & Function · doi:10.1039/d0fo03346d · Cited by 19

The significance of macroautophagy in health and disease

Tukaj, C. (2013) · Folia Morphologica · doi:10.5603/fm.2013.0015 · Cited by 20

Characterization and Quenching of Autofluorescence in Piglet Testis Tissue and Cells

Yang, Y., & Honaramooz, A. (2012) · Anatomy Research International · doi:10.1155/2012/820120 · Cited by 18

Getting on in Old Age: How the Gut Microbiota Interferes With Brain Innate Immunity

Mossad, O., & Blank, T. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.698126 · Cited by 18

Transient inhibition of mitochondrial function by chrysin and apigenin prolong longevity via mitohormesis in C. elegans

Cheng, Y., Hou, B.-H., Xie, G., Shao, Y.-T., Yang, J., & Xu, C. (2023) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2023.03.264 · Cited by 20

Consumption of commonly used artificial food dyes increases activity and oxidative stress in the animal model Caenorhabditis elegans

Guerrero‐Rubio, M. A., Hernández‐García, S., García‐Carmona, F., & Gandía‐Herrero, F. (2023) · Food Research International · doi:10.1016/j.foodres.2023.112925 · Cited by 18

Effects of iron homeostasis on epigenetic age acceleration: a two-sample Mendelian randomization study

Wang, Z., Liu, Y., Zhang, S., Yuan, Y., Chen, S., Li, W., Zuo, M., Xiang, Y., Li, T., Yang, Y., et al. (2023) · Clinical Epigenetics · doi:10.1186/s13148-023-01575-w · Cited by 18

Antioxidant and antiaging activities of the polysaccharide ZJP-04M from Ziziphus jujuba in Caenorhabditis elegans

Liu, Q., Yi, Y.-L., Liang, X., Wu, M.-T., Li, J., Chen, X., Zhang, F., Ruan, Q., Liu, F., Duan, J., et al. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.138208 · Cited by 18

Carbofuran affects cellular autophagy and developmental senescence through the impairment of Nrf2 signalling

Khan, A., Zaman, T., Fahad, T. M., Akther, T., Hasan, M. F., Naz, T., & Kishi, S. (2021) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.16774 · Cited by 18

Principles of brain aging: Status and challenges of modeling human molecular changes in mice

Kluever, V., & Fornasiero, E. F. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101465 · Cited by 18

Inhibition of Nigral Microglial Activation Reduces Age-Related Loss of Dopaminergic Neurons and Motor Deficits

Wang, T.-F., Wu, S.-Y., Pan, B., Tsai, S., & Kuo, Y. (2022) · Cells · doi:10.3390/cells11030481 · Cited by 18

Increased intra-mitochondrial lipofuscin aggregates with spherical dense body formation in mitochondrial myopathy

Lu, J., Monaco, C. M. F., Hawke, T. J., Yan, C., & Tarnopolsky, M. A. (2020) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2020.116816 · Cited by 18

Lysosome-targeted stress reveals increased stability of lipofuscin-containing lysosomes

Stroikin, Y., Mild, H., Johansson, U., Roberg, K. B., & Öllinger, K. M. (2008) · AGE · doi:10.1007/s11357-007-9045-9 · Cited by 18

Detection of hepatic maturation by Raman spectroscopy in mesenchymal stromal cells undergoing hepatic differentiation

Wu, H.-H., Ho, J. H., & Lee, O. K. (2016) · Stem Cell Research & Therapy · doi:10.1186/s13287-015-0259-y · Cited by 17

Cellular senescence, rejuvenation and potential immortality

SHELDRAKE, A. R. (2022) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2021.2434 · Cited by 17

Restoration of Lysosomal and Mitochondrial Function Through p38 Mitogen-Activated Protein Kinase Inhibition Ameliorates Senescence

Park, J. Y., Lee, H., Song, E. S., Lee, Y. H., Kuk, M. U., Ko, G., Kwon, H. W., Byun, Y., & Park, J. T. (2022) · Rejuvenation Research · doi:10.1089/rej.2022.0043 · Cited by 17

Gelsenicine disrupted the intestinal barrier of Caenorhabditis elegans

Wu, Z., Zhang, J., Wu, Y., Chen, M., Hu, H., Gao, X., Li, C., Li, M., Zhang, Y.-B., Lin, X., et al. (2024) · Chemico-Biological Interactions · doi:10.1016/j.cbi.2024.111036 · Cited by 17

Accumulation of lipofuscin‐like pigments of walnuts (Carya cathayensis) during storage: potential roles of lipid oxidation and non‐enzymatic glycosylation

Li, W., Gao, H., Fang, X., Tao, F., Chen, H., Mu, H., & Jiang, Y. (2014) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6587 · Cited by 17

Assembly of the fluorescent acrosomal matrix and its fate in fertilization in the water strider, Aquarius remigis

Miyata, H., Noda, N., Fairbairn, D. J., Oldenbourg, R., & Cardullo, R. A. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22413 · Cited by 17

Progressive accumulation of autofluorescent granules in macrophages in rat striatum after systemic 3-nitropropionic acid: a correlative light- and electron-microscopic study

Riew, T., Kim, H. L., Choi, J.-H., Jin, X., Shin, Y., & Lee, M. (2017) · Histochemistry and Cell Biology · doi:10.1007/s00418-017-1589-x · Cited by 17

An ecotoxicological approach for the Boka Kotorska Bay (south-eastern Adriatic Sea): First evaluation of lysosomal responses and metallothionein induction in mussels

Ros, L. D., Moschino, V., Macic, V., & Schintu, M. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.03.015 · Cited by 17

Autophagy negatively regulates pro-osteogenic activity in human aortic valve interstitial cells

Deng, X., Meng, X., Venardos, N. M., Song, R., Yamanaka, K., Fullerton, D. A., & Jaggers, J. J. (2017) · Journal of Surgical Research · doi:10.1016/j.jss.2017.05.088 · Cited by 17

Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO

Zeng, L., Sun, C., Pei, Z., Yun, T., Fan, S., Long, S., Wu, T., Chen, Z., Zhi-min, Y., & Xu, F. (2019) · Biogerontology · doi:10.1007/s10522-019-09820-7 · Cited by 17

An integrated approach to determine interactive genotoxic and global gene expression effects of multiwalled carbon nanotubes (MWCNTs) and benzo[a]pyrene (BaP) on marine mussels: evidence of reverse ‘Trojan Horse’ effects

Barranger, A., Rance, G. A., Aminot, Y., Dallas, L. J., Sforzini, S., Weston, N. J., Lodge, R. W., Bannı, M., Arlt, V. M., Moore, M. N., et al. (2019) · Nanotoxicology · doi:10.1080/17435390.2019.1654003 · Cited by 17

Expansion of the Golgi apparatus in rat cerebral cortex following intracerebroventricular injections

Grieb, P., Kryczka, T., Fiedorowicz, M., Frontczak‐Baniewicz, M., & Walski, M. (2004) · Acta Neurobiologiae Experimentalis · doi:10.55782/ane-2004-1531 · Cited by 17

In silico analysis of gene expression profiles in the olfactory mucosae of aging senescence‐accelerated mice

Getchell, T. V., Peng, X., Green, C. P., Stromberg, A. J., Chen, K.-C., Mattson, M. P., & Getchell, M. L. (2004) · Journal of Neuroscience Research · doi:10.1002/jnr.20157 · Cited by 17

Replicative Senescence and Expression of Autophagy Genes in Mesenchymal Stromal Cells

Ratushnyy, A. Y., Rudimova, Y. V., & Buravkova, L. B. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920100053 · Cited by 16

Label-free optical metabolic imaging of adipose tissues for prediabetes diagnosis

Chen, L., Qin, G., Liu, Y., Li, M., Li, Y., Guo, L., Du, L., Zheng, W., Wu, P., Chuang, Y.-H., et al. (2023) · Theranostics · doi:10.7150/thno.82697 · Cited by 17

Proteostasis in T cell aging

Gressler, A. E., Leng, H., Zinecker, H., & Simon, A. K. (2023) · Seminars in Immunology · doi:10.1016/j.smim.2023.101838 · Cited by 15

Therapy-induced normal tissue damage promotes breast cancer metastasis

Perkins, D. W., Steiner, I., Haider, S., Robertson, D. M., Buus, R., O’Leary, L., & Isacke, C. M. (2023) · iScience · doi:10.1016/j.isci.2023.108503 · Cited by 19

EGCG Alleviates the Aging Toxicity Induced by 3-MCPD via IIS Pathway in Caenorhabditis elegans with Abnormal Reproduction and Heat Shock Protein

Liu, D., Song, Y., Zheng, B., Xie, J., Chen, Y., Xie, J., Chen, X., & Yu, Q. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c09583 · Cited by 19

Regional differences in age-related lipofuscin accumulation in the female hamster brainstem

Gerrits, P. O., Kortekaas, R., de Weerd, H., Veening, J. G., & van der Want, J. J. L. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.03.015 · Cited by 16

Anti-oxidative hormetic effects of cellular autophagy induced by nutrient deprivation in a molluscan animal model

Moore, M. N., Shaw, J. P., Pascoe, C. K., Beesley, A., Viarengo, A., & Lowe, D. M. (2020) · Marine Environmental Research · doi:10.1016/j.marenvres.2020.104903 · Cited by 16

Accumulation of lipofuscin in broiler chicken with wooden breast

Hasegawa, Y., Kawasaki, T., Maeda, N., YAMADA, M., Takahashi, N., Watanabe, T., & Iwasaki, T. (2021) · Animal Science Journal · doi:10.1111/asj.13517 · Cited by 16

The Antioxidative Role of Chaperone-Mediated Autophagy as a Downstream Regulator of Oxidative Stress in Human Diseases

Le, S., Fu, X., Pang, M., Zhou, Y., Yin, G., Zhang, J., & Fan, D. (2022) · Technology in Cancer Research & Treatment · doi:10.1177/15330338221114178 · Cited by 18

Attenuation of iron‐binding proteins in ARPE ‐19 cells reduces their resistance to oxidative stress

Karlsson, M., & Kurz, T. (2016) · Acta Ophthalmologica · doi:10.1111/aos.13076 · Cited by 16

Comparison of Left Ventricular Myocardial Structure and Function in Patients with Aortic Stenosis and Those with Pure Aortic Regurgitation

Mannacio, V. A., Guadagno, E., Mannacio, L., Cervasio, M., Antignano, A., Mottola, M., Gagliardi, C., & Vosa, C. (2015) · Cardiology · doi:10.1159/000431283 · Cited by 16

Molecular medicine in ophthalmic care

RICHER, S. P., Stiles, W. R., & Thomas, C. (2009) · Optometry · doi:10.1016/j.optm.2009.03.018 · Cited by 16

Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome

Gracanin, M., Lam, M. A., Morgan, P. E., Rodgers, K. J., Hawkins, C. L., & Davies, M. J. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.11.019 · Cited by 15

Mitral and Tufted Cells Are Potential Cellular Targets of Nitration in the Olfactory Bulb of Aged Mice

Yang, M. J., Sim, S., Jeon, J. H., Jeong, E., Kim, H.-C., Park, Y.-J., & Kim, I. (2013) · PLoS ONE · doi:10.1371/journal.pone.0059673 · Cited by 16

2-Hydroxypropyl-beta-cyclodextrin (HPβCD) reduces age-related lipofuscin accumulation through a cholesterol-associated pathway

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Significance of green granules in neutrophils and monocytes

Gorup, T., Cohen, A. T., Sybenga, A. B., & Rappaport, E. S. (2017) · Baylor University Medical Center Proceedings · doi:10.1080/08998280.2017.1391045 · Cited by 16

Recombinant buckwheat glutaredoxin intake increases lifespan and stress resistance via hsf-1 upregulation in Caenorhabditis elegans

Li, F., Ma, X., Cui, X., Li, J., & Wang, Z. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.01.028 · Cited by 16

Cerebral metabolism in a mouse model of Alzheimer’s disease characterized by two-photon fluorescence lifetime microscopy of intrinsic NADH

Gómez, C. A., Fu, B., Sakadžić, S., & Yaseen, M. A. (2018) · Neurophotonics · doi:10.1117/1.nph.5.4.045008 · Cited by 15

Drusen maculopathy: a risk factor for AMD. Can we prevent visual loss?

Algvere, P., & Seregard, S. (2003) · Acta ophthalmologica · doi:10.1034/j.1600-0420.2003.00157.x · Cited by 19

Questioning the use of biochemical extraction to measure lipofuscin for age determination of crabs: Comment on Ju et al. (1999, 2001)

Sheehy, M. R. J. (2007) · Marine Ecology Progress Series · doi:10.3354/meps07352 · Cited by 16

Neuronal collagen XVII is localized to lipofuscin granules

Seppänen, A., Miettinen, R. A., & Alafuzoff, I. I. (2010) · Neuroreport · doi:10.1097/wnr.0b013e3283405352 · Cited by 16

Magnesium Isoglycyrrhizinate Ameliorates Concanavalin A-Induced Liver Injury by Inhibiting Autophagy

Fan, Z., Li, Y., Chen, S., Xu, L., Tian, Y., Cao, Y., Pan, Z., Zhang, X., Chen, Y., & Ren, F. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.794319 · Cited by 15

BECN1F121A mutation increases autophagic flux in aged mice and improves aging phenotypes in an organ-dependent manner

Sebti, S., Zou, Z., & Shiloh, M. U. (2022) · Autophagy · doi:10.1080/15548627.2022.2111852 · Cited by 14

Fosthiazate exposure induces oxidative stress, nerve damage, and reproductive disorders in nontarget nematodes

Liu, S., Wu, Q., Zhong, Y., He, Z., Wang, Z., Li, R., & Wang, M. (2022) · Environmental Science and Pollution Research · doi:10.1007/s11356-022-23010-y · Cited by 15

Progress in Frontotemporal Dementia Research

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Worms eat oil: Alcanivorax borkumensis hydrocarbonoclastic bacteria colonise Caenorhabditis elegans nematodes intestines as a first step towards oil spills zooremediation

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Age-Related Macular Degeneration: What Do We Know So Far?

Ma, H. H., & Liutkevičienė, R. (2021) · Acta medica Lituanica · doi:10.15388/amed.2021.28.1.7 · Cited by 16

Antioxidant and Free Radical Scavenging Potential of Yakuchinone B Derivatives in Reduction of Lipofuscin Formation Using H2O2-Treated Neuroblastoma Cells

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Can Lipofuscin Accumulation Be Prevented?

Kurz, T. (2007) · Rejuvenation Research · doi:10.1089/rej.2007.0621 · Cited by 15

Aspects of the digestive gland cells of the mussel Mytilus galloprovincialis, in relation to lysosomal enzymes, lipofuscin presence and shell size: Contribution in the assessment of marine pollution biomarkers

Raftopoulou, E. K., & Dimitriadis, V. K. (2012) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.12.017 · Cited by 15

Does smoking influence the type of age related macular degeneration causing visual impairment?

Dandekar, S. S. (2006) · British Journal of Ophthalmology · doi:10.1136/bjo.2005.086355 · Cited by 15

Analysis of Forsythia suspensa fruit and leaf extracts using UHPLC-Q-Exactive-Orbitrap/MS: In vivo antioxidant activity on D-galactose-induced aging mice

Wang, X., Jia, Q., Yao, X., Yang, L., Pei, K., Guo, L., Yu, G., Yang, Y., & Qin, N. (2024) · Food Chemistry · doi:10.1016/j.foodchem.2024.141002 · Cited by 15

The role of mitochondria in cytokine and chemokine signalling during ageing

Kalykaki, M., Rubio‐Tomás, T., & Tavernarakis, N. (2024) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2024.111993 · Cited by 14

The dispersal flight of Tribolium castaneum – A field test of laboratory generated predictions

Gurdasani, K., Rafter, M. A., Daglish, G. J., & Walter, G. H. (2019) · Journal of Stored Products Research · doi:10.1016/j.jspr.2019.05.009 · Cited by 14

Thiophene‐Based Optical Ligands That Selectively Detect Aβ Pathology in Alzheimer's Disease

Klingstedt, T., Shirani, H., Ghetti, B. F., Vidal, R., & Nilsson, K. P. R. (2021) · ChemBioChem · doi:10.1002/cbic.202100199 · Cited by 14

Cellular Degradation Machineries in Age-Related Loss of Muscle Mass (Sarcopenia)

Altun, M., GrönholdtKlein, M., Wang, L., & Ulfhake, B. (2012) · InTech eBooks · doi:10.5772/34274 · Cited by 14

Ultrastructural changes of posterior lingual glands after hypoglossal denervation in hamsters

Cheng, S., Huang, C.-Y., Chen, Y. C., Lee, J., Chang, H., Chen, H. M., Chiang, M.-L., Kuo, M. Y., Kok, S., & Tseng, C. Y. (2008) · Journal of Anatomy · doi:10.1111/j.1469-7580.2008.01019.x · Cited by 14

SkinspanTM: A Healthy Longevity Framework for Skin Aging

Wyles, S. P., Maredia, H. S., Ansaf, R. B., Dweydari, M., Hurt, R. T., Bonnes, S. L. R., Khosla, S., LeBrasseur, N. K., Draelos, Z. D., & Davis, M. D. P. (2025) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2025.07.027 · Cited by 16

Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age

Caulfield, M. E., Werp, M. J. V., Stancati, J. A., Collier, T. J., Sortwell, C. E., Sandoval, I. M., Manfredsson, F. P., & Steece‐Collier, K. (2023) · Neurobiology of Disease · doi:10.1016/j.nbd.2023.106111 · Cited by 13

The role of endolysosomal progranulin and TMEM106B in neurodegenerative diseases

Takahashi, H., & Strittmatter, S. M. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00873-6 · Cited by 14

Mortality and histopathological effects in harbour-transplanted snails with different exposure histories

Bighiu, M. A., Watermann, B. T., Guo, X., Almroth, B. C., & Eriksson‐Wiklund, A. (2017) · Aquatic Toxicology · doi:10.1016/j.aquatox.2017.06.018 · Cited by 13

Histological Changes of the Testicular Interstitium during Postnatal Development in Microminipigs

Kangawa, A., Otake, M., Enya, S., Yoshida, T., & Shibata, M. (2019) · Toxicologic Pathology · doi:10.1177/0192623319827477 · Cited by 13

A2E Distribution in RPE Granules in Human Eyes

Guan, Z., Li, Y., Jiao, S., Yeasmin, N., Rosenfeld, P. J., Dubovy, S. R., Lam, B. L., & Wen, R. (2020) · Molecules · doi:10.3390/molecules25061413 · Cited by 13

Increased serum lipofuscin associated with leukocyte telomere shortening in veterans: a possible role for sulfur mustard exposure in delayed-onset accelerated cellular senescence

Nasiri, L., Mahdavi, M. R. V., Hassanpour, H., Ghazanfari, T., Ardestani, S. K., Askari, N., Majd, M.-A. M., & Rahimlou, B. (2022) · International Immunopharmacology · doi:10.1016/j.intimp.2022.109549 · Cited by 14

Age-related lysosomal dysfunction: an unrecognized roadblock for cobalamin trafficking?

Zhao, H., Brunk, U. T., & Garner, B. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0861-9 · Cited by 13

Lysosomal and lipid-associated parameters in the livers of three species of arctic seabird chicks: Species differences and relationships with contaminant levels

Hegseth, M. N., Regoli, F., Gorbi, S., Bocchetti, R., Gabrielsen, G. W., & Camus, L. (2011) · Marine Pollution Bulletin · doi:10.1016/j.marpolbul.2011.06.011 · Cited by 13

Autophagy in response to environmental stresses: New monitoring perspectives

Tang, B. L. (2015) · Ecological Indicators · doi:10.1016/j.ecolind.2015.07.022 · Cited by 13

Müller Cells and the Retinal Pigment Epithelium

Gullapalli, V. K., Sugino, I. K., & Zarbin, M. A. (2008) · Elsevier eBooks · doi:10.1016/b978-1-4160-0016-7.50128-4 · Cited by 13

Ultrastructural pathology of oligodendrocytes in the white matter in continuous paranoid schizophrenia: a role for microglia

Uranova, N. A., Vikhreva, O. V., Рахманова, В. И., & Orlovskaya, D. D. (2017) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro20171179176-81 · Cited by 13

Lipofuscin-dependent stimulation of microglial cells

Leclaire, M. D., Nettels-Hackert, G., König, J., Höhn, A., Grune, T., Uhlig, C. E., Hansen, U. J., Eter, N., & Heiduschka, P. (2019) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-019-04253-x · Cited by 13

The origin of lipofuscin in brown adipocytes of hyperinsulinaemic rats: the role of lipid peroxidation and iron.

Markelic, M. B., Veličković, K., Golić, I., Klepal, W., Otašević, V., Stančić, A., Janković, A., Vučetić, M., Buzadžić, B., Korać, B., et al. (2013) · PubMed · doi:10.14670/hh-28.493 · Cited by 13

Lipofuscin pigment can be used as a prognostic marker in prostatic adenocarcinoma

Mahmoodi, M., Shunli, Z., Salim, S., Hou, J. S., & Garcia, F. U. (2006) · Annals of Diagnostic Pathology · doi:10.1016/j.anndiagpath.2005.12.007 · Cited by 13

Mild heat stress induces hormetic effects in protecting the primary culture of mouse prefrontal cerebrocortical neurons from neuropathological alterations

Mane, N. R., Gajare, K. A., & Deshmukh, A. A. (2018) · IBRO Reports · doi:10.1016/j.ibror.2018.11.002 · Cited by 12

Proteasome Biology: Chemistry and Bioengineering Insights

Račková, L., & Csekes, E. (2020) · Polymers · doi:10.3390/polym12122909 · Cited by 14

Senescent Cells: Dual Implications on the Retinal Vascular System

Habibi-Kavashkohie, M. R., Scorza, T., & Oubaha, M. (2023) · Cells · doi:10.3390/cells12192341 · Cited by 12

Angelica keiskei water extract Mitigates Age-Associated Physiological Decline in Mice

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Mapping the Research of Ferroptosis in Parkinson’s Disease from 2013 to 2023: A Scientometric Review

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