Lipofuscin: mechanisms of age-related accumulation and influence on cell function12 1Guest Editor: Rajindar S. Sohal 2This article is part of a series of reviews on “Oxidative Stress and Aging.” The full list of papers may be found on the homepage of the journal.

Aging: a theory based on free radical and radiation chemistry

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The Free Radical Theory of Aging Matures

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The mitochondrial‐lysosomal axis theory of aging

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Lysosomal Storage Diseases

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The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells.

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Retinal age pigments generated by self-assembling lysosomotropic detergents

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Grape seed proanthocyanidin extract and swimming training enhances neuronal number in dorso-medial prefrontal cortex in middle-aged male rats by alleviating oxidative stress

Satpati, A., Tripathi, S. J., Rao, B. S. S., & Devi, S. A. (2019) · Journal of Functional Foods · doi:10.1016/j.jff.2019.103693 · Cited by 11

Increased lipofuscin on endomyocardial biopsy predicts greater cardiac improvement in adolescents and young adults

Parson, S. J., Russell, S. D., Bennett, M. K., Dunn, J. M., Gilotra, N. A., Rao, S. D., Harrington, C. M., Freitag, T. B., Foster, M. C., & Halushka, M. K. (2011) · Cardiovascular Pathology · doi:10.1016/j.carpath.2011.11.002 · Cited by 11

Protective effects of 1,3‐diaryl‐2‐propen‐1‐one derivatives against H2O2‐induced damage in SK‐N‐MC cells

Bayati, S., Yazdanparast, R., Majd, S. S., & Oh, S. (2010) · Journal of Applied Toxicology · doi:10.1002/jat.1594 · Cited by 11

Protein thiol oxidation does not change in skeletal muscles of aging female mice

Tohma, H., El-Shafey, A. F., Croft, K. D., Shavlakadze, T., Grounds, M. D., & Arthur, P. G. (2013) · Biogerontology · doi:10.1007/s10522-013-9483-y · Cited by 11

Ginger and alpha lipoic acid ameliorate age-related ultrastructural changes in rat liver

Mahmoud, Y. I., & Hegazy, H. G. (2015) · Biotechnic & Histochemistry · doi:10.3109/10520295.2015.1076578 · Cited by 11

Temperate marine herbivorous fishes will likely do worse, not better, as waters warm up

Trip, E. D. L., Clements, K. D., Raubenheimer, D., & Choat, J. H. (2016) · Marine Biology · doi:10.1007/s00227-015-2790-x · Cited by 12

Lysosomal Storage Disorders and Iron

Brás, J. (2013) · International review of neurobiology · doi:10.1016/b978-0-12-410502-7.00012-0 · Cited by 11

Lipofuscin Accumulation into and Clearance from Retinal Pigment Epithelium Lysosomes: Physiopathology and Emerging Therapeutics

Nociari, M., Kiss, S., & Rodriguez-Boulan, E. J. (2017) · InTech eBooks · doi:10.5772/intechopen.69304 · Cited by 11

A natural variation-based screen in mouse cells reveals USF2 as a regulator of the DNA damage response and cellular senescence

Kang, T., Moore, E. C., Kopania, E. E. K., King, C. D., Schilling, B., Campisi, J., Good, J. M., & Brem, R. B. (2023) · G3: Genes, Genomes, Genetics · doi:10.1093/g3journal/jkad091 · Cited by 10

Toxoplasma gondii causes lipofuscinosis, collagenopathy and spleen and white pulp atrophy during the acute phase of infection.

Pereira, A. V., Gois, M. B., Silva, M. S., de Miranda, N. R., Campos, C. B. H. F., Schneider, L., Barbosa, C. P., Nogueira-Melo, G. D. A., & Sant'Ana, D. D. M. G. (2019) · Pathogens and Disease · doi:10.1093/femspd/ftaa008 · Cited by 8

Neuronal Cell Rearrangement During Aging: Antioxidant Compounds as a Potential Therapeutic Approach

Bej, E., Cesare, P., d’Angelo, M., Volpe, A. R., & Castelli, V. (2024) · Cells · doi:10.3390/cells13231945 · Cited by 11

Iron metabolism in rheumatic diseases

Givian, A., Azizan, A., Jamshidi, A., Mahmoudi, M., & Farhadi, E. (2025) · Journal of Translational Autoimmunity · doi:10.1016/j.jtauto.2025.100267 · Cited by 10

Efficient removal of naturally-occurring lipofuscin autofluorescence in human nervous tissue using high-intensity white light

Sapio, M. R., King, D. M., Maric, D., Shah, S. S., TALBOT, T. L., Manalo, A. P., Nara, P., Ma, W., Ghetti, A., Ramsden, C. E., et al. (2025) · Journal of Pain · doi:10.1016/j.jpain.2025.105359 · Cited by 10

Obesity, longevity, quality of life

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Cellular Senescence in Adrenocortical Biology and Its Disorders

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Histological alterations as a recommended biomarker in the mussel Mytilus platensis (Bivalvia, Mytilidae) to study anthropic impact on seaports

Leis, M., Abad, T. N., Martinez, M., Calcagno, J. A., Sabatini, S. E., & Genovese, G. (2024) · Regional Studies in Marine Science · doi:10.1016/j.rsma.2024.103373 · Cited by 10

Thiophene-Based Ligands for Specific Assignment of Distinct Aβ Pathologies in Alzheimer's Disease

Klingstedt, T., Lantz, L., Shirani, H., Ge, J., Hanrieder, J., Vidal, R., Ghetti, B. F., & Nilsson, K. P. R. (2024) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.4c00021 · Cited by 11

Transaminase profile and hepatic histopathological traits in Piaractus mesopotamicus exposed to insecticide Diflubenzuron

Silva, A. L. N., Rodrigues, R. A., Siqueira, M. S., Farias, K. N. N., Kuibida, K. V., Franco‐Belussi, L., & Fernandes, C. E. (2021) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-12013-2 · Cited by 10

Retinal Fundus Imaging in Mouse Models of Retinal Diseases

Alex, A. F., Heiduschka, P., & Eter, N. (2012) · Methods in molecular biology · doi:10.1007/978-1-62703-080-9_3 · Cited by 10

Polysaccharide from Ganoderma atrum delay senescence and enhance stress resistance through modulating IIS and MAPK pathway in Caenorhabditis elegans

Xie, J., Shu, M., Chen, X., Xie, J., Chen, Y., Hu, X., Nie, C., Liu, D., & Yu, Q. (2025) · Food Research International · doi:10.1016/j.foodres.2025.117215 · Cited by 9

A pH-responsive anthocyanin-based hydrogel with colorimetric infection monitoring and antibacterial properties for wound healing

Miao, J., Chai, H., Song, L., Liao, X., Chen, S., Xiao, Y., & Wang, R. (2025) · Journal of Materials Chemistry B · doi:10.1039/d5tb01386k · Cited by 9

PFOS-induced black liver and hepatic aging in mice: A new paradigm in environmental hepatotoxicology

Stevenson, C. K., Wang, J., & Du, C. (2025) · Environment International · doi:10.1016/j.envint.2025.109999 · Cited by 9

Quantitative Autofluorescence in Non-Neovascular Age Related Macular Degeneration

Chandra, S., Grewal, M. K., Gurudas, S., Sondh, R. S., Bird, A. C., Jeffery, G., Chong, V. N., & Sivaprasad, S. (2023) · Biomedicines · doi:10.3390/biomedicines11020560 · Cited by 9

Ganoderma lucidum methyl ganoderate E extends lifespan and modulates aging-related indicators in Caenorhabditis elegans

Okoro, N. O., Odiba, A. S., Han, J., Osadebe, P. O., Omeje, E. O., Liao, G., Liu, Y., Jin, C., Fang, W., Liu, H., et al. (2023) · Food & Function · doi:10.1039/d3fo04166b · Cited by 9

Establishing chronic models of age-related macular degeneration via long-term iron ion overload

Huang, H., Zeng, J., Yu, X., Du, H., Wen, C., Mao, Y., Tang, H., Kuang, X., Liu, W., Yu, H., et al. (2024) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00532.2023 · Cited by 9

Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition

Zhao, H., Ruberu, K. R., Li, H., & Garner, B. (2014) · Bioscience Reports · doi:10.1042/bsr20130130 · Cited by 8

Wnt Glycation Inhibits Canonical Signaling

Ye, Z.-N., Mittag, S., Schmidt, M., Simm, A., Horstkorte, R., & Huber, O. (2019) · Cells · doi:10.3390/cells8111320 · Cited by 9

Lipofuscin in saliva and plasma and its association with age in healthy adults

Feng, F.-K., Lingling, E., Kong, X., Wang, D., & Liu, H. (2015) · Aging Clinical and Experimental Research · doi:10.1007/s40520-015-0326-3 · Cited by 9

Changes in Lysosomes and Their Autophagic Function in Aging: The Comparative Biology of Lysosomal Function

Orenstein, S. J., & Cuervo, A. M. (2009) · Springer eBooks · doi:10.1007/978-90-481-3465-6_10 · Cited by 9

Effects of glycowithanolides on lipid peroxidation and lipofuscinogenesis in male reproductive organs of mice.

Walvekar, M. V., Shaikh, N., & Sarvalkar, P. P. (2013) · Europe PMC (PubMed Central) · Cited by 9

Problems associated with a lipofuscin extraction method used to age blue crabs Callinectes sapidus cultured in Florida, USA

Crowley, C., Gandy, R. L., Daly, K., & Vleet, E. S. V. (2014) · Aquatic Biology · doi:10.3354/ab00572 · Cited by 9

Characterising the variables associated with Tribolium castaneum adults that initiate flight in laboratory tests – Generating predictions for the field

Gurdasani, K., Rafter, M. A., Daglish, G. J., & Walter, G. H. (2018) · Journal of Stored Products Research · doi:10.1016/j.jspr.2018.10.005 · Cited by 9

Occurrence and characterization of lipofuscin and ceroid in human atherosclerotic plaque

Perrotta, I. D. (2018) · Ultrastructural Pathology · doi:10.1080/01913123.2018.1544953 · Cited by 9

Developmental Programming: Impact of Prenatal Exposure to Bisphenol A on Senescence and Circadian Mediators in the Liver of Sheep

Motta, G., Thangaraj, S. V., & Padmanabhan, V. (2023) · Toxics · doi:10.3390/toxics12010015 · Cited by 8

Sauchinone Ameliorates Senescence Through Reducing Mitochondrial ROS Production

Kuk, M. U., Lee, Y. H., Kim, D., Lee, K. S., Park, J. H., Yoon, J. H., Lee, Y. J., So, B., Kim, M., Kwon, H. W., et al. (2025) · Antioxidants · doi:10.3390/antiox14030259 · Cited by 8

Senolytics as Modulators of Critical Signaling Pathways: a Promising Strategy to Combat Brain Aging and Neurodegenerative Disorders

Singh, I., & Singh, A. K. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05504-1 · Cited by 10

Maintenance and Decline of Neuronal Lysosomal Function in Aging

Zhong, R., & Richardson, C. E. (2025) · Cells · doi:10.3390/cells14241976 · Cited by 8

Histomorphometric evaluation of melanomacrophage centers (MMCs) and CD3+ T cells of two morphs of brown trout (Salmo trutta) fed diets with immunostimulants

Kasprzak, R., Zakęś, Z., Kamaszewski, M., Szudrowicz, H., Wiechetek, W., Janusz, J. R., Ostaszewska, T., Korzelecka-Orkisz, A., & Formicki, K. (2023) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2023.109020 · Cited by 8

Rapid, reversible and addressable immobilization of Caenorhabditis elegans in Pluronic F-127 using an optoelectric device

Chuang, H.-S., & Chuang, W.-Y. (2017) · Sensors and Actuators B Chemical · doi:10.1016/j.snb.2017.06.130 · Cited by 8

Polyglucosan Bodies in Aged Brain and Neurodegeneration: Cause or Consequence?

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Brown Bowel Syndrome

Arnold, C. A., BURKE, A. P., Calomeni, E. P., Mayer, R. C., Rishi, A., Singhi, A. D., Stashek, K. M., Voltaggio, L., & Tondon, R. (2020) · The American Journal of Surgical Pathology · doi:10.1097/pas.0000000000001443 · Cited by 8

Analysis of age-related left ventricular collagen remodeling in living donors: Implications in arrhythmogenesis

García‐Mendívil, L., Pérez‐Zabalza, M., Mountris, K. A., Duwé, S., Smisdom, N., Pérez, M. M., Luján, L., Wolfs, E., Driesen, R. B., Vallejo‐Gil, J. M., et al. (2022) · iScience · doi:10.1016/j.isci.2022.103822 · Cited by 8

Mitochondria and Parkinson's Disease

Simon, D. K., Chu, C. T., & Swerdlow, R. H. (2011) · Parkinson s Disease · doi:10.4061/2011/261791 · Cited by 8

Kinins

Fredrik Leeb-Lundberg, L. M. (2011) · De Gruyter eBooks · doi:10.1515/9783110252354 · Cited by 8

Choroidal neovascular membrane in a series of cases of malignant melanoma of the choroid

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The Immortal Senescence

Bianchi, A., Lipchick, B. C., & Nikiforov, M. A. (2016) · Methods in molecular biology · doi:10.1007/978-1-4939-6670-7_1 · Cited by 8

Two-Photon Imaging of Neural Networks in a Mouse Model of Alzheimer’s DiseasePreprint

Eichhoff, G., & Garaschuk, O. (2011) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot065789 · Cited by 8

Mechanistic insights into fasting-induced autophagy in the aging heart

Parvaresh, H., Paczek, K., Al‐Bari, M. A. A., & Eid, N. A. S. (2024) · World Journal of Cardiology · doi:10.4330/wjc.v16.i3.109 · Cited by 8

Bisretinoid lipofuscin, fundus autofluorescence and retinal disease

Sparrow, J. R., & Kim, H. J. (2025) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2025.101388 · Cited by 7

Toward Systemic Lipofuscin Removal

Renteln, M. (2024) · Rejuvenation Research · doi:10.1089/rej.2024.0034 · Cited by 8

prominin-1 -null Xenopus laevis develop subretinal drusenoid-like deposits, cone-rod dystrophy and RPE atrophy

Carr, B. J., Skitsko, D., Kriese, L. M., Song, J. L., Li, Z., Ju, M. J., & Moritz, O. L. (2024) · Journal of Cell Science · doi:10.1242/jcs.262298 · Cited by 7

What is the effect of fasting on the lifespan of neurons?

Kalsi, D. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.07.010 · Cited by 8

Lack of Autophagy Induction by Lithium Decreases Neuroprotective Effects in the Striatum of Aged Rats

Costa, A., Erustes, A. G., Sinigaglia‐Coimbra, R., Girardi, C. E. N., Pereira, G. J. S., Ureshino, R. P., & Smaili, S. S. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13020135 · Cited by 8

Ageing, Metabolic Dysfunction, and the Therapeutic Role of Antioxidants

Santos, A. L., & Sinha, S. (2023) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-3-031-26576-1_15 · Cited by 8

Mitochondrial homeostasis: a potential target for delaying renal aging

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D ipeptidylpeptidase‐4‐targeted activatable fluorescent probes visualize senescent cells

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Identification of a small molecule preventing BMSC senescence in vitro by improving intracellular homeostasis via ANXA7 and Hmbox1

Wang, F.-W., Zhao, F., Qian, X.-Y., Yu, Z.-Z., Zhao, J., Su, L., Zhang, Y., Zhang, S., Zhao, B., & Miao, J. (2014) · RSC Advances · doi:10.1039/c4ra10404h · Cited by 7

Characteristics of neuronal lipofuscin in the superior temporal gyrus in Alzheimer’s disease do not differ from non-diseased controls: a comparison with disease-related changes in the superior frontal gyrus

Mountjoy, C., Dowson, J., Harrington, C., Cairns, M. R., & Wilton-Cox, H. (2005) · Acta Neuropathologica · doi:10.1007/s00401-005-0993-9 · Cited by 8

Live-Cell Imaging of Phagosome Motility in Primary Mouse RPE Cells

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The vivo antioxidant activity of self-made aged garlic extract on the d -galactose-induced mice and its mechanism research via gene chip analysis

Wang, X., Yang, Y., & Zhang, M. (2019) · RSC Advances · doi:10.1039/c8ra10308a · Cited by 7

AGEING INDUCES APOPTOSIS AND INCREASES HSP70 STRESS PROTEIN IN THE EPIDIDYMIS OF Octodon degus

Bustos‐Obregón, E., & Esponda, P. (2004) · International Journal of Morphology · doi:10.4067/s0717-95022004000100005 · Cited by 7

Individual variability in the structural properties of neurons in the human inferior olive

Baizer, J. S., Wong, K. M., Sherwood, C. C., Hof, P. R., & Witelson, S. F. (2017) · Brain Structure and Function · doi:10.1007/s00429-017-1580-2 · Cited by 7

Oxidative Stress and Protein Oxidation

Grune, T., Catalgol, B., & Jung, T. (2012) · Wiley eBooks · doi:10.1002/9781118493038.ch1 · Cited by 7

Decrowding Expansion Pathology: Unmasking Previously Invisible Nanostructures and Cells in Intact Human Brain Pathology SpecimensPreprint

Valdes, P. A., Yu, C.-C., Aronson, J., Zhao, Y., Bernstock, J. D., Bhere, D., An, B., Viapiano, M. S., Shah, K., Chiocca, E. A., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.12.05.471271 · Cited by 7

Astaxanthin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity by scavenging singlet oxygen

Kitao, M., Yamaguchi, A., Tomioka, T., Kai, K., Kamei, Y., Sugimoto, K., & Akagawa, M. (2023) · Free Radical Research · doi:10.1080/10715762.2023.2277144 · Cited by 6

Multitarget Protective Effects of JUB on Aβ-Induced Neurotoxicity and the Mechanism Predication Using Network Pharmacology Analysis

Liu, J., Zhang, Y., Lai, C., & Xie, J. (2023) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.3c06430 · Cited by 6

Sake lees extract obtained using a novel continuous phase-transition extraction method: evaluation of its bioactive composition, anti-aging efficacy and mechanism

Zou, X., Xiao, Y., Ke, L., Nie, Y., Xiao, J., Yang, J., Guo, C., & Liu, X. (2025) · Food & Function · doi:10.1039/d5fo00291e · Cited by 6

Luteolin protects human ARPE-19 retinal pigment epithelium cells from blue light-induced phototoxicity through activation of Nrf2/Keap1 signaling

Hayakawa, R., Ishii, T., Fushimi, T., Kamei, Y., Yamaguchi, A., Sugimoto, K., Ashida, H., & Akagawa, M. (2025) · Free Radical Research · doi:10.1080/10715762.2025.2503832 · Cited by 6

Nematicidal activity of 3-indoleacetonitrile against Bursaphelenchus xylophilus: Inhibition of development and reproduction through induction of excessive reactive oxygen species

Yu, S., Mao, T., Shang, Y., Sun, J., Liu, P. G., & Jin, L. H. (2025) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2025.106509 · Cited by 6

The Relationship between Age-Related Macular Degeneration and Olfactory Function

Kar, T., Yıldırım, Y., Altundağ, A., Sönmez, M., Kaya, A., Çolakoğlu, K., Tekelı, H., Çayönü, M., & Hummel, T. R. (2015) · Neurodegenerative Diseases · doi:10.1159/000381216 · Cited by 6

Lipofuscin Granules in the Epileptic Human Temporal Neocortex with Age

Merlo, S., Nakayama, A. B., Brusco, J., Rossi, M. A., Carlotti, C. G., & Moreira, J. E. (2015) · Ultrastructural Pathology · doi:10.3109/01913123.2015.1043416 · Cited by 6

Pseudomelanosis coli, its relation to laxative use and association with colorectal neoplasms: A comprehensive review

Mohammed, A., Paranji, N., Singh, A., & Sanaka, M. R. (2021) · JGH Open · doi:10.1002/jgh3.12546 · Cited by 6

Relationship between Postural Stability, Lead Content, and Selected Parameters of Oxidative Stress

Wąsik, M., Miśkiewicz-Orczyk, K., Słota, M., Lisowska, G., Kasperczyk, A., Bellanti, F., Dobrakowski, M., Błaszczyk, U., Bułdak, R. J., & Kasperczyk, S. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms232112768 · Cited by 7

Patient-Derived Cellular Models for Polytarget Precision Medicine in Pantothenate Kinase-Associated Neurodegeneration

Álvarez-Córdoba, M., Talaverón-Rey, M., Povea-Cabello, S., Cilleros-Holgado, P., Gómez-Fernández, D., Piñero-Pérez, R., Reche-López, D., Munuera-Cabeza, M., Suárez-Carrillo, A., Romero-González, A., et al. (2023) · Pharmaceuticals · doi:10.3390/ph16101359 · Cited by 6

Early postnatal development of rat brain is accompanied by generation of lipofuscin-like pigments

Wilhelm, J., Ivica, J., Kagan, D., & Svoboda, P. (2010) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-010-0623-2 · Cited by 6

Protective Effects of Flavonoid Baicalein against Menadione-Induced Damage in SK-N-MC Cells

Moslehi, M., & Yazdanparast, R. (2013) · CellBio · doi:10.4236/cellbio.2013.22005 · Cited by 6

Zebrafish as Aging Models

Kishi, S. (2006) · Elsevier eBooks · doi:10.1016/b978-012369391-4/50029-1 · Cited by 6

Type, Topography, and Sequelae of Neuropathological Changes Shaping Clinical Phenotype of Autism

Węgiel, J., Wısnıewskı, T., Chauhan, A., Chauhan, V. P. S., Kuchna, I., Nowicki, K., Imaki, H., Wegiel, J., Ma, S., Wierzba‐Bobrowicz, T., et al. (2009) · CRC Press eBooks · doi:10.1201/9781420068870-c1 · Cited by 6

The involvement of dityrosine crosslinks in lipofuscin accumulation in Alzheimer’s disease

Al‐Hilaly, Y. K., Mohammed, A. H., Thorpe, J. R., & Serpell, L. C. (2019) · Journal of Physics Conference Series · doi:10.1088/1742-6596/1294/6/062107 · Cited by 6

Heterogeneity of Structure and Fluorescence of Single Lipofuscin Granule from Retinal Pigment Epithelium of Human Donor Eyes: Study with the Use of Atomic Force Microscopy and Near-Field Microscopy

Petrukhin, A. N., Astafiev, A. A., Zolotavin, P., Feldman, T. B., Dontsov, A. E., Sarkisov, O. M., & Оstrovsky, М. А. (2005) · Doklady Biochemistry and Biophysics · doi:10.1007/s10628-005-0136-1 · Cited by 6

Growth and recruitment rates of juvenile blue crabs ( Callinectes sapidus) in Chesapeake Bay

Puckett, B. J. (2006) · University Libraries (University of Maryland) · Cited by 6

Optimized immunofluorescence for liver structure analysis: Enhancing 3D resolution and minimizing tissue autofluorescence

Zoppolato, E., Mol, H., Estrella-García, C., Vizcaino-Rodríguez, N., Sanchez, D., Procel, N., Baroja, I., Sansores-García, L., & Moya, I. M. (2025) · Biology Methods and Protocols · doi:10.1093/biomethods/bpaf023 · Cited by 6

Low-Molecular-Weight Bovine Collagen Peptides Reduce Fat Accumulation in C. elegans and Ameliorate Obesity-Related Metabolic Dysfunction and Microbiota Diversity in C57BL/6 Male Diet-Induced Obese Mice

Lópeź‐Yoldi, M., Aranaz, P., Riezu‐Boj, J. I., González-Salazar, I., Izco, J. M., Recalde, J. I., González-Navarro, C. J., & Milagro, F. I. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26189149 · Cited by 5

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Influence of selected phenolic acids on advanced lipid oxidation end products generation in model systems

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Autofluorescence in freshly isolated adult human liver sinusoidal cells

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Detecting senescent fate in mesenchymal stem cells: a combined cytofluorimetric and ultrastructural approach

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The natural phytochemical trans‐communic acid inhibits cellular senescence and pigmentation through FoxO3a activation

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Effects of diets high in corn oil or in extra virgin olive oil on oxidative stress in an experimental model of breast cancer

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Longevity effects of hispidol in Caenorhabditis elegans

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Structure-activity relationship of 15 different Mn-salen derivatives against free radicals

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Dynamic Scaling of Lipofuscin Deposition in Aging Cells

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Alzheimer's Disease: From Animal Models to the Human Syndrome

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Lipofuscin

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Lipofuscin: Mechanisms of formation and increase with age

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Lipofuscinogenesis in a model system of cultured cardiac myocytes

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