Negative Regulation and Gain Control of Sensory Neurons by the C. elegans Calcineurin TAX-6

THE GENETICS OF CAENORHABDITIS ELEGANS

Brenner, S. (1974) · Genetics · doi:10.1093/genetics/77.1.71 · Cited by 14,985 · see citing works

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Caterina, M. J., Schumacher, M. A., Tominaga, M., Rosen, T. A., Levine, J. D., & Julius, D. J. (1997) · Nature · doi:10.1038/39807 · Cited by 9,132 · see citing works

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

Liu, J., Farmer, J. D., Lane, W. S., Friedman, J., Weissman, I., & Schreiber, S. L. (1991) · Cell · doi:10.1016/0092-8674(91)90124-h · Cited by 4,116 · see citing works

Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences.

Mello, C. C., Kramer, J. M., Stinchcomb, D. T., & Ambros, V. (1991) · The EMBO Journal · doi:10.1002/j.1460-2075.1991.tb04966.x · Cited by 3,069 · see citing works

THE STRUCTURE AND REGULATION OF PROTEIN PHOSPHATASES

Cohen, P. (1989) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.58.070189.002321 · Cited by 2,547 · see citing works

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

Clipstone, N. A., & Crabtree, G. R. (1992) · Nature · doi:10.1038/357695a0 · Cited by 1,635 · see citing works

A capsaicin-receptor homologue with a high threshold for noxious heat

Caterina, M. J., Rosen, T. A., Tominaga, M., Brake, A. J., & Julius, D. J. (1999) · Nature · doi:10.1038/18906 · Cited by 1,599 · see citing works

Odorant-selective genes and neurons mediate olfaction in C. elegans

Bargmann, C. I., Hartwieg, E. A., & Horvitz, H. R. (1993) · Cell · doi:10.1016/0092-8674(93)80053-h · Cited by 1,211 · see citing works

Ca 2+ -Induced Apoptosis Through Calcineurin Dephosphorylation of BAD

Wang, H., Pathan, N., Ethell, I. M., Krajewski, S., Yamaguchi, Y., Shibasaki, F., McKeon, F., Bobo, T., Franke, T. F., & Reed, J. C. (1999) · Science · doi:10.1126/science.284.5412.339 · Cited by 1,132 · see citing works

FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurin

O’Keefe, S. J., Tamura, J., Kincaid, R. L., Tocci, M. J., & O’Neill, E. A. (1992) · Nature · doi:10.1038/357692a0 · Cited by 841 · see citing works

Crystal structures of human calcineurin and the human FKBP12–FK506–calcineurin complex

Kissinger, C. R., Parge, H. E., Knighton, D. R., Lewis, C. T., Pelletier, L. A., Tempczyk, A., Kalish, V. J., Tucker, K. D., Showalter, R. E., Moomaw, E. W., et al. (1995) · Nature · doi:10.1038/378641a0 · Cited by 762 · see citing works

Chemosensory neurons with overlapping functions direct chemotaxis to multiple chemicals in C. elegans

Bargmann, C. I., & Horvitz, H. R. (1991) · Neuron · doi:10.1016/0896-6273(91)90276-6 · Cited by 740 · see citing works

Generic Signals and Specific Outcomes

Crabtree, G. R. (1999) · Cell · doi:10.1016/s0092-8674(00)80571-1 · Cited by 730 · see citing works

Synaptic plasticity in the hippocampus: LTP and LTD

Malenka, R. C. (1994) · Cell · doi:10.1016/0092-8674(94)90517-7 · Cited by 655 · see citing works

OSM-9, A Novel Protein with Structural Similarity to Channels, Is Required for Olfaction, Mechanosensation, and Olfactory Adaptation in Caenorhabditis elegans

Colbert, H. A., Smith, T. L., & Bargmann, C. I. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-21-08259.1997 · Cited by 625 · see citing works

Neural regulation of thermotaxis in Caenorhabditis elegans

Mori, I., & Ohshima, Y. (1995) · Nature · doi:10.1038/376344a0 · Cited by 600 · see citing works

Normal and mutant thermotaxis in the nematode Caenorhabditis elegans.

Hedgecock, E. M., & Russell, R. L. (1975) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.72.10.4061 · Cited by 568 · see citing works

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4

Shibasaki, F., Price, E. R., Milan, D. J., & McKeon, F. (1996) · Nature · doi:10.1038/382370a0 · Cited by 487 · see citing works

A dual mechanosensory and chemosensory neuron in Caenorhabditis elegans.

Kaplan, J. M., & Horvitz, H. R. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.6.2227 · Cited by 487 · see citing works

Inducible and Reversible Enhancement of Learning, Memory, and Long-Term Potentiation by Genetic Inhibition of Calcineurin

Malleret, G., Haditsch, U., Genoux, D., Jones, M. W., Bliss, T. V. P., Vanhoose, A. M., Weitlauf, C., Kandel, E. R., Winder, D. G., & Mansuy, I. M. (2001) · Cell · doi:10.1016/s0092-8674(01)00264-1 · Cited by 470 · see citing works

Mutations in a Cyclic Nucleotide–Gated Channel Lead to Abnormal Thermosensation and Chemosensation in C. elegans

Komatsu, H., Mori, I., Rhee, J.-S., Akaike, N., & Ohshima, Y. (1996) · Neuron · doi:10.1016/s0896-6273(00)80202-0 · Cited by 446 · see citing works

A Putative Cyclic Nucleotide–Gated Channel Is Required for Sensory Development and Function in C. elegans

Coburn, C. M., & Bargmann, C. I. (1996) · Neuron · doi:10.1016/s0896-6273(00)80201-9 · Cited by 441 · see citing works

Guanylyl cyclase expression in specific sensory neurons: A new family of chemosensory receptors

Yu, S. S. B., Avery, L., Baude, E. J., & Garbers, D. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.7.3384 · Cited by 430 · see citing works

Synaptic code for sensory modalities revealed by C. elegans GLR-1 glutamate receptor

Hart, A. C., Sims, S., & Kaplan, J. M. (1995) · Nature · doi:10.1038/378082a0 · Cited by 426 · see citing works

Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans.

Okkema, P. G., Harrison, S. M. W., Plunger, V., Aryana, A., & Fire, A. Z. (1993) · Genetics · doi:10.1093/genetics/135.2.385 · Cited by 416 · see citing works

Rhodopsin phosphorylation as a mechanism of cyclic GMP phosphodiesterase regulation by S-modulin

Kawamura, S. (1993) · Nature · doi:10.1038/362855a0 · Cited by 402 · see citing works

Odorant-specific adaptation pathways generate olfactory plasticity in C. elegans

Colbert, H. A., & Bargmann, C. I. (1995) · Neuron · doi:10.1016/0896-6273(95)90224-4 · Cited by 377 · see citing works

Active Currents Regulate Sensitivity and Dynamic Range in C. elegans Neurons

Goodman, M. B., Hall, D. H., Avery, L., & Lockery, S. R. (1998) · Neuron · doi:10.1016/s0896-6273(00)81014-4 · Cited by 370 · see citing works

Restricted and Regulated Overexpression Reveals Calcineurin as a Key Component in the Transition from Short-Term to Long-Term Memory

Mansuy, I. M., Mayford, M. R., Jacob, B., Kandel, E. R., & Bach, M. E. (1998) · Cell · doi:10.1016/s0092-8674(00)80897-1 · Cited by 361 · see citing works

Synaptic plasticity in the hippocampus

Bliss, T. (1979) · Trends in Neurosciences · doi:10.1016/0166-2236(79)90019-5 · Cited by 351 · see citing works

Genetic and Pharmacological Evidence for a Novel, Intermediate Phase of Long-Term Potentiation Suppressed by Calcineurin

Winder, D. G., Mansuy, I. M., Osman, M., Moallem, T. M., & Kandel, E. R. (1998) · Cell · doi:10.1016/s0092-8674(00)80896-x · Cited by 350 · see citing works

Mechanosensory signalling in C. elegans mediated by the GLR-1 glutamate receptor

Maricq, A. V., Peckol, E. L., Driscoll, M., & Bargmann, C. I. (1995) · Nature · doi:10.1038/378078a0 · Cited by 330 · see citing works

Mechanisms of Rhodopsin Inactivation in Vivo as Revealed by a COOH-Terminal Truncation Mutant

Chen, J., Makino, C. L., Peachey, N. S., Baylor, D. A., & Simon, M. I. (1995) · Science · doi:10.1126/science.7824934 · Cited by 311 · see citing works

The Gα Protein ODR-3 Mediates Olfactory and Nociceptive Function and Controls Cilium Morphogenesis in C. elegans Olfactory Neurons

Roayaie, K., Crump, J. G., Sagasti, A., & Bargmann, C. I. (1998) · Neuron · doi:10.1016/s0896-6273(00)80434-1 · Cited by 308 · see citing works

Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase

Cyert, M. S., Kunisawa, R., Kaim, D., & Thorner, J. (1991) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.88.16.7376 · Cited by 289 · see citing works

Identification of an autoinhibitory domain in calcineurin.

Hashimoto, Y., Perrino, B. A., & Soderling, T. R. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39919-3 · Cited by 263 · see citing works

Regulation of Interneuron Function in the C. elegans Thermoregulatory Pathway by the ttx-3 LIM Homeobox Gene

Hobert, O., Mori, I., Yamashita, Y., Honda, H., Ohshima, Y., Liu, Y., & Ruvkun, G. (1997) · Neuron · doi:10.1016/s0896-6273(00)80944-7 · Cited by 262 · see citing works

OSMOTIC AVOIDANCE DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

Culotti, J. G., & Russell, R. L. (1978) · Genetics · doi:10.1093/genetics/90.2.243 · Cited by 250 · see citing works

Inhibition of Rhodopsin Kinase by Recoverin

Klenchin, V. A., Calvert, P. D., & Bownds, M. D. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.27.16147 · Cited by 208 · see citing works

Recoverin has S-modulin activity in frog rods

Kawamura, S., Hisatomi, O., Kayada, S., Tokunaga, F., & Kuo, C. H. (1993) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)82369-9 · Cited by 186 · see citing works

Rhodopsin Phosphorylation and Dephosphorylation in Vivo

Ohguro, H., Hooser, J. P. V., Milam, A. H., & Palczewski, K. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.24.14259 · Cited by 183 · see citing works

Trans-splicing and polycistronic transcription in Caenohabditis elegans

Blumenthal, T. (1995) · Trends in Genetics · doi:10.1016/s0168-9525(00)89026-5 · Cited by 178 · see citing works

Genetics of Chemotaxis and Thermotaxis in the Nematode Caenorhabditis Elegans

Mori, I. (1999) · Annual Review of Genetics · doi:10.1146/annurev.genet.33.1.399 · Cited by 173 · see citing works

The distribution of calcineurin in rat brain by light and electron microscopic immunohistochemistry and enzyme-immunoassay

Goto, S., Matsukado, Y., Mihara, Y., Inoue, N., & Miyamoto, E. (1986) · Brain Research · doi:10.1016/0006-8993(86)91381-8 · Cited by 170 · see citing works

Regulation of Calcineurin by Growth Cone Calcium Waves Controls Neurite Extension

Lautermilch, N. J., & Spitzer, N. C. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-01-00315.2000 · Cited by 164 · see citing works

The structure of the B subunit of calcineurin

Aitken, A., Klee, C. B., & Cohen, P. (1984) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1984.tb08055.x · Cited by 157 · see citing works

unc-3, a gene required for axonal guidance in Caenorhabditis elegans, encodes a member of the O/E family of transcription factors

Prasad, B. C., Ye, B., Zackhary, R., Schrader, K. A., Seydoux, G., & Reed, R. R. (1998) · Development · doi:10.1242/dev.125.8.1561 · Cited by 154 · see citing works

CHEMOTAXIS-DEFECTIVE MUTANTS OF THE NEMATODE CAENORHABDITIS ELEGANS

Dusenbery, D. B., Sheridan, R. E., & Russell, R. L. (1975) · Genetics · doi:10.1093/genetics/80.2.297 · Cited by 139 · see citing works

Cloning and characterization of molecular isoforms of the catalytic subunit of calcineurin using nonisotopic methods.

Kincaid, R. L., Giri, P. R., Higuchi, S., Tamura, J., DIXON, S. C., Marietta, C. A., Amorese, D. A., & Martin, B. M. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)38593-x · Cited by 131 · see citing works

Distinct Cellular Expression of Calcineurin Aα and Aβ in Rat Brain

Kuno, T., Mukai, H., Itô, A., Chang, C., Kishima, K., Saito, N., & Tanaka, C. (1992) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1992.tb10036.x · Cited by 127 · see citing works

Functional reconstitution of a heteromeric cyclic nucleotide-gated channel of Caenorhabditis elegans in cultured cells

Komatsu, H., Jin, Y., L’Étoile, N. D., Mori, I., Bargmann, C. I., Akaike, N., & Ohshima, Y. (1999) · Brain Research · doi:10.1016/s0006-8993(99)01111-7 · Cited by 115 · see citing works

The complete primary structure of calcineurin A, a calmodulin binding protein homologous with protein phosphatases 1 and 2A

Itô, A., Hashimoto, T., Hirai, M., Takeda, T., Shuntoh, H., Kuno, T., & Tanaka, C. (1989) · Biochemical and Biophysical Research Communications · doi:10.1016/0006-291x(89)91148-0 · Cited by 109 · see citing works

The UNC-14 protein required for axonal elongation and guidance in Caenorhabditis elegans interacts with the serine/threonine kinase UNC-51.Preprint

Ogura, K., Shirakawa, M., Barnes, T. M., Hekimi, S., & Ohshima, Y. (1997) · Genes & Development · doi:10.1101/gad.11.14.1801 · Cited by 88 · see citing works

An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans

Takeuchi, M., Kawakami, M., Ishihara, T., Amano, T., Kondo, K., & Katsura, I. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.20.11775 · Cited by 62 · see citing works

Intercistronic Region Required for Polycistronic Pre-mRNA Processing in Caenorhabditis elegans

Huang, T., Kuersten, S., Deshpande, A. M., Spieth, J., MacMorris, M., & Blumenthal, T. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1111-1120.2001 · Cited by 54 · see citing works

Amino Acid Residues of S-modulin Responsible for Interaction with Rhodopsin Kinase

Tachibanaki, S., Nanda, K., Sasaki, K., Ozaki, K., & Kawamura, S. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.5.3313 · Cited by 34 · see citing works

Molecular Characterization of Neurally Expressing Genes in the para Sodium Channel Gene Cluster of Drosophila

Hong, C., & Ganetzky, B. (1996) · Genetics · doi:10.1093/genetics/142.3.879 · Cited by 29 · see citing works

Chemosensation in C. elegans

Bargmann, C. I. (2006) · WormBook · doi:10.1895/wormbook.1.123.1 · Cited by 787 · see citing works

NEURONAL SUBSTRATES OF COMPLEX BEHAVIORS IN C. ELEGANS

de Bono, M., & Maricq, A. V. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.27.070203.144259 · Cited by 401 · see citing works

An elegant mind: Learning and memory in <i>Caenorhabditis elegans</i>

Ardiel, E. L., & Rankin, C. H. (2010) · Learning &amp; Memory · doi:10.1101/lm.960510 · Cited by 323 · see citing works

Quantitative Mass Spectrometry Identifies Insulin Signaling Targets in C. elegans

Dong, M., Venable, J. D., Au, N., Xu, T., Park, S. K., Cociorva, D., Johnson, J. R., Dillin, A. G., & Yates, J. R. (2007) · Science · doi:10.1126/science.1139952 · Cited by 310 · see citing works

Calcineurin signaling and NFAT activation in cardiovascular and skeletal muscle development

Schulz, R. A., & Yutzey, K. E. (2003) · Developmental Biology · doi:10.1016/j.ydbio.2003.10.008 · Cited by 291 · see citing works

The C. elegans Thermosensory Neuron AFD Responds to Warming

Kimura, K. D., Miyawaki, A., Matsumoto, K., & Mori, I. (2004) · Current Biology · doi:10.1016/j.cub.2004.06.060 · Cited by 220 · see citing works

The Cyclic GMP-Dependent Protein Kinase EGL-4 Regulates Olfactory Adaptation in C. elegans

L’Étoile, N. D., Coburn, C. M., Eastham, J., Kistler, A. L., Gallegos, G., & Bargmann, C. I. (2002) · Neuron · doi:10.1016/s0896-6273(02)01066-8 · Cited by 202 · see citing works

Running hot and cold: behavioral strategies, neural circuits, and the molecular machinery for thermotaxis in <i>C. elegans</i> and <i>Drosophila</i>

Garrity, P. A., Goodman, M. B., Samuel, A. D., & Sengupta, P. (2010) · Genes &amp; Development · doi:10.1101/gad.1953710 · Cited by 197 · see citing works

Identification and characterization of novel nicotinic receptor‐associated proteins in Caenorhabditis elegans

GOTTSCHALK, A. R., Almedom, R. B., Schedletzky, T., Anderson, S., Yates, J. R., & Schafer, W. R. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600741 · Cited by 185 · see citing works

Regulation of the Longevity Response to Temperature by Thermosensory Neurons in Caenorhabditis elegans

Lee, S., & Kenyon, C. J. (2009) · Current Biology · doi:10.1016/j.cub.2009.03.041 · Cited by 178 · see citing works

Identification of Guanylyl Cyclases That Function in Thermosensory Neurons of Caenorhabditis elegans

Inada, H., Itô, H., Satterlee, J. S., Sengupta, P., Matsumoto, K., & Mori, I. (2006) · Genetics · doi:10.1534/genetics.105.050013 · Cited by 178 · see citing works

Behavioral plasticity in C. elegans: Paradigms, circuits, genes

Hobert, O. (2002) · Journal of Neurobiology · doi:10.1002/neu.10168 · Cited by 173 · see citing works

C. elegansfeeding defective mutants have shorter body lengths and increased autophagy

Mörck, C., & Pilon, M. (2006) · BMC Developmental Biology · doi:10.1186/1471-213x-6-39 · Cited by 171 · see citing works

Calcineurin: a central controller of signalling in eukaryotes: Workshop on the Calcium/Calcineurin/NFAT Pathway: Regulation and Function

Aramburu, J., Heitman, J., & Crabtree, G. R. (2004) · The EMBO Reports · doi:10.1038/sj.embor.7400133 · Cited by 156 · see citing works

Ca2+-Operated Transcriptional Networks: Molecular Mechanisms and In Vivo Models

Mellström, B., Savignac, M., Gómez‐Villafuertes, R., & Naranjo, J. R. (2008) · Physiological Reviews · doi:10.1152/physrev.00041.2005 · Cited by 152 · see citing works

Genetic Control of Temperature Preference in the Nematode Caenorhabditis elegans

Mohri, A., Kodama, E., Kimura, K. D., Koike, M., Mizuno, T., & Mori, I. (2005) · Genetics · doi:10.1534/genetics.104.036111 · Cited by 145 · see citing works

The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation

Chung, S., Clark, D. A., Gabel, C. V., Mazur, E., & Samuel, A. D. T. (2006) · BMC Neuroscience · doi:10.1186/1471-2202-7-30 · Cited by 144 · see citing works

Insulin-like signaling and the neural circuit for integrative behavior in C. elegansPreprint

Kodama, E., Kuhara, A., Mohri‐Shiomi, A., Kimura, K. D., Okumura, M., Tomioka, M., Iino, Y., & Mori, I. (2006) · Genes & Development · doi:10.1101/gad.1479906 · Cited by 142 · see citing works

Chemosensory signal transduction in Caenorhabditis elegans

Ferkey, D. M., Sengupta, P., & L’Étoile, N. D. (2021) · Genetics · doi:10.1093/genetics/iyab004 · Cited by 133 · see citing works

Neural Circuits Mediate Electrosensory Behavior inCaenorhabditis elegans

Gabel, C. V., Gabel, H. W., Pavlichin, D. S., Kao, A., Clark, D. A., & Samuel, A. D. T. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0775-07.2007 · Cited by 120 · see citing works

Calcineurin, a Calcium/Calmodulin-dependent Protein Phosphatase, Is Involved in Movement, Fertility, Egg Laying, and Growth inCaenorhabditis elegans

Bandyopadhyay, J., Lee, J., Lee, J., Lee, J. I., Yu, J.-R., Jee, C., Cho, J. H., Jung, S., Lee, M., Zannoni, S., et al. (2002) · Molecular Biology of the Cell · doi:10.1091/mbc.e02-01-0005 · Cited by 115 · see citing works

Antagonistic sensory cues generate gustatory plasticity in Caenorhabditis elegans

Hukema, R. K., Rademakers, S., Dekkers, M. P., Burghoorn, J., & Jansen, G. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7600940 · Cited by 111 · see citing works

Ouabain Induces Apoptotic Cell Death in Type I Spiral Ganglion Neurons, but not Type II Neurons

Lang, H., Schulte, B. A., & Schmiedt, R. A. (2005) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-004-5021-6 · Cited by 112 · see citing works

Light and pheromone-sensing neurons regulates cold habituation through insulin signalling in Caenorhabditis elegans

Ohta, A., Ujisawa, T., Sonoda, S., & Kuhara, A. (2014) · Nature Communications · doi:10.1038/ncomms5412 · Cited by 104 · see citing works

G Protein-Coupled Receptor Kinase Function Is Essential for Chemosensation in C. elegans

Fukuto, H. S., Ferkey, D. M., Apicella, A. J., Lans, H., Sharmeen, T., Chen, W., Lefkowitz, R. J., Jansen, G., Schafer, W. R., & Hart, A. C. (2004) · Neuron · doi:10.1016/s0896-6273(04)00252-1 · Cited by 103 · see citing works

Diverse regulation of sensory signaling by C. elegans nPKC‐epsilon/eta TTX‐4

Okochi, Y., Kimura, K. D., Ohta, A., & Mori, I. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600697 · Cited by 100 · see citing works

A diacylglycerol kinase modulates long-term thermotactic behavioral plasticity in C. elegans

Biron, D., Shibuya, M., Gabel, C. V., Wasserman, S. M., Clark, D. A., Brown, A. R., Sengupta, P., & Samuel, A. D. T. (2006) · Nature Neuroscience · doi:10.1038/nn1796 · Cited by 94 · see citing works

Gustatory plasticity inC. elegansinvolves integration of negative cues and NaCl taste mediated by serotonin, dopamine, and glutamatePreprint

Hukema, R. K., Rademakers, S., & Jansen, G. (2008) · Learning & Memory · doi:10.1101/lm.994408 · Cited by 90 · see citing works

Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor

Juang, B.-T., Gu, C., Starnes, L. M., Palladino, F., Goga, A., Kennedy, S. G., & L’Étoile, N. D. (2013) · Cell · doi:10.1016/j.cell.2013.08.006 · Cited by 89 · see citing works

G o α regulates olfactory adaptation by antagonizing G q α-DAG signaling in Caenorhabditis elegans

Matsuki, M., Kunitomo, H., & Iino, Y. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0506954103 · Cited by 87 · see citing works

KIN‐29 SIK regulates chemoreceptor gene expression via an MEF2 transcription factor and a class II HDAC

van der Linden, A. M., Nolan, K. M., & Sengupta, P. (2006) · The EMBO Journal · doi:10.1038/sj.emboj.7601479 · Cited by 87 · see citing works

Ancient neuromodulation by vasopressin/oxytocin-related peptides

Beets, I., Temmerman, L., Janssen, T. A. H., & Schoofs, L. (2013) · Worm · doi:10.4161/worm.24246 · Cited by 85 · see citing works

Neural coding in a single sensory neuron controlling opposite seeking behaviours in Caenorhabditis elegans

Kuhara, A., Ohnishi, N., Shimowada, T., & Mori, I. (2011) · Nature Communications · doi:10.1038/ncomms1352 · Cited by 89 · see citing works

Temperature sensing across species

McKemy, D. D. (2007) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-006-0199-6 · Cited by 84 · see citing works

Structural Delineation of the Calcineurin–NFAT Interaction and its Parallels to PP1 Targeting Interactions

Li, H., Rao, A., & Hogan, P. G. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.07.068 · Cited by 81 · see citing works

Worm thermotaxis: a model system for analyzing thermosensation and neural plasticity

Mori, I., Sasakura, H., & Kuhara, A. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.11.010 · Cited by 80 · see citing works

Casein Kinase II and Calcineurin Modulate TRPP Function and Ciliary Localization

Hu, J., Bae, Y. K., Knobel, K. M., & Barr, M. M. (2006) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-10-0935 · Cited by 73 · see citing works

Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegansPreprint

Tanizawa, Y., Kuhara, A., Inada, H., Kodama, E., Mizuno, T., & Mori, I. (2006) · Genes & Development · doi:10.1101/gad.1497806 · Cited by 69 · see citing works

Thermotaxis of C. elegans as a model for temperature perception, neural information processing and neural plasticity

Kimata, T., Sasakura, H., Ohnishi, N., Nishio, N., & Mori, I. (2012) · Worm · doi:10.4161/worm.19504 · Cited by 68 · see citing works

C. elegans G Protein Regulator RGS-3 Controls Sensitivity to Sensory Stimuli

Ferkey, D. M., Hyde, R., Haspel, G., Dionne, H. M., Hess, H. A., Suzuki, H., Schafer, W. R., Koelle, M. R., & Hart, A. C. (2007) · Neuron · doi:10.1016/j.neuron.2006.11.015 · Cited by 65 · see citing works

Distinct thermal migration behaviors in response to different thermal gradients in Caenorhabditis elegans

Jurado, P., Kodama, E., Tanizawa, Y., & Mori, I. (2009) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2009.00549.x · Cited by 63 · see citing works

Regulators of AWC-Mediated Olfactory Plasticity in Caenorhabditis elegans

O’Halloran, D. M., Altshuler-Keylin, S., Lee, J. I., & L’Étoile, N. D. (2009) · PLoS Genetics · doi:10.1371/journal.pgen.1000761 · Cited by 62 · see citing works

CAMKII and Calcineurin regulate the lifespan of Caenorhabditis elegans through the FOXO transcription factor DAF-16

Li, T., Xie, Q., Ding, Y., Li, S., Peng, S., Zhang, Y., Tan, D., Yuan, Z., & Dong, M. (2013) · eLife · doi:10.7554/elife.00518 · Cited by 59 · see citing works

Molecular Physiology of the Neural Circuit for Calcineurin-Dependent Associative Learning inCaenorhabditis elegans

Kuhara, A., & Mori, I. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.0517-06.2006 · Cited by 57 · see citing works

The phosphatase calcineurin regulates pathological TDP-43 phosphorylation

Liachko, N. F., Saxton, A. D., McMillan, P. J., Strovas, T. J., Currey, H. N., Taylor, L. M., Wheeler, J. M., Oblak, A. L., Ghetti, B. F., Montine, T. J., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1600-y · Cited by 57 · see citing works

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans

Ghosh, R., Mohammadi, A., Kruglyak, L., & Ryu, W. S. (2012) · BMC Biology · doi:10.1186/1741-7007-10-85 · Cited by 55 · see citing works

Investigating the molecular mechanisms of learning and memory using Caenorhabditis elegans

Rahmani, A., & Chew, Y. L. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15510 · Cited by 52 · see citing works

Molecular biology of thermosensory transduction in C. elegans

Aoki, I., & Mori, I. (2015) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2015.03.011 · Cited by 49 · see citing works

Regulatory machinery of UNC‐33 Ce‐CRMP localization in neurites during neuronal development in Caenorhabditis elegans

Tsuboi, D., Hikita, T., Qadota, H., Amano, M., & Kaibuchi, K. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03490.x · Cited by 49 · see citing works

Contrasting dynamic responses in vivo of the Bcl-xL and Bim erythropoietic survival pathways

Koulnis, M., Porpiglia, E., Porpiglia, A., Liu, Y., Hallstrom, K., Hidalgo, D., & Socolovsky, M. (2011) · Blood · doi:10.1182/blood-2011-07-365346 · Cited by 48 · see citing works

The Caenorhabditis elegans Homologue of Down Syndrome Critical Region 1, RCN-1, Inhibits Multiple Functions of the Phosphatase Calcineurin

Lee, J. I., Dhakal, B. K., Lee, J., Bandyopadhyay, J., Jeong, S. Y., Eom, S. H., Kim, D. H., & Ahnn, J. (2003) · Journal of Molecular Biology · doi:10.1016/s0022-2836(03)00237-7 · Cited by 48 · see citing works

Sperm Affects Head Sensory Neuron in Temperature Tolerance of Caenorhabditis elegans

Sonoda, S., Ohta, A., Maruo, A., Ujisawa, T., & Kuhara, A. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.05.078 · Cited by 46 · see citing works

Temperature and food mediate long-term thermotactic behavioral plasticity by association-independent mechanisms in C. elegans

Chi, C. A., Clark, D. A., Lee, S. J., Biron, D., Luo, L., Gabel, C. V., Brown, J. W., Sengupta, P., & Samuel, A. D. T. (2007) · Journal of Experimental Biology · doi:10.1242/jeb.006551 · Cited by 44 · see citing works

Ciliopathy proteins establish a bipartite signaling compartment in aC. elegansthermosensory neuron

Nguyen, P. A. T., Liou, W., Hall, D. H., & Leroux, M. R. (2014) · Journal of Cell Science · doi:10.1242/jcs.157610 · Cited by 39 · see citing works

Opposing Functions of Calcineurin and CaMKII Regulate G-protein Signaling in Egg-laying Behavior of C.elegans

Lee, J., Jee, C., Song, H., Bandyopadhyay, J., Lee, J. I., Yu, J.-R., Lee, J., Park, B.-J., & Ahnn, J. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.09.050 · Cited by 37 · see citing works

Neural circuit‐dependent odor adaptation in C. elegans is regulated by the Ras‐MAPK pathway

Hirotsu, T., & Iino, Y. (2005) · Genes to Cells · doi:10.1111/j.1365-2443.2005.00856.x · Cited by 38 · see citing works

C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization

Fernando, T. R., Flibotte, S., Xiong, S., Yin, J., Yzeiraj, E., Moerman, D. G., Meléndez, A., & Savage‐Dunn, C. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.01.016 · Cited by 37 · see citing works

Gain-of-function mutations in the UNC-2/CaV2α channel lead to excitation-dominant synaptic transmission in Caenorhabditis elegans

Huang, Y.-C., Pirri, J. K., Rayes, D., Gao, S., Mulcahy, B., Grant, J., Saheki, Y., Francis, M. M., Zhen, M., & Alkema, M. J. (2019) · eLife · doi:10.7554/elife.45905 · Cited by 37 · see citing works

Generation and modulation of chemosensory behaviors in C. elegans

Sengupta, P. (2007) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-006-0196-9 · Cited by 33 · see citing works

Two Forms of Learning following Training to a Single Odorant in Caenorhabditis elegans AWC Neurons

Pereira, S., & van der Kooy, D. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.4221-11.2012 · Cited by 33 · see citing works

Verapamil extends lifespan in Caenorhabditis elegans by inhibiting calcineurin activity and promoting autophagy

Liu, W., Lin, H., Mao, Z., Zhang, L., Bao, K., Jiang, B., Xia, C., Li, W.-J., Hu, Z., & Li, J. (2020) · Aging · doi:10.18632/aging.102951 · Cited by 34 · see citing works

The inner junction protein CFAP20 functions in motile and non-motile cilia and is critical for vision

Chrystal, P. W., Lambacher, N. J., Doucette, L. P., Bellingham, J., Schiff, E. R., Noel, N. C. L., Li, C., Tsiropoulou, S., Casey, G. A., Zhai, Y., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33820-w · Cited by 31 · see citing works

Environmental Alkalinity Sensing Mediated by the Transmembrane Guanylyl Cyclase GCY-14 in C. elegans

Murayama, T., Takayama, J., Fujiwara, M., & MARUYAMA, I. N. (2013) · Current Biology · doi:10.1016/j.cub.2013.04.052 · Cited by 31 · see citing works

Evolutionarily Conserved Role of Calcineurin in Phosphodegron-Dependent Degradation of Phosphodiesterase 4D

Zhu, H., Suk, H. Y., Yu, R. Y.-L., Brancho, D., Olabisi, O. A., Yang, T. T. C., Yang, X., Zhang, J., Moussaif, M., Durand, J. L., et al. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01193-09 · Cited by 31 · see citing works

Age‐dependent changes in response property and morphology of a thermosensory neuron and thermotaxis behavior in Caenorhabditis elegans

Huang, T., Matsuyama, H. J., Tsukada, Y., Singhvi, A., Syu, R., Lu, Y., Shaham, S., Mori, I., & Pan, C. (2020) · Aging Cell · doi:10.1111/acel.13146 · Cited by 29 · see citing works

Caenorhabditis elegansglutamate transporter deletion induces AMPA‐receptor/adenylyl cyclase 9‐dependent excitotoxicity

Mano, I., & Driscoll, M. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05804.x · Cited by 28 · see citing works

Calcineurin in Animal Behavior

Lee, J. I., & Ahnn, J. (2004) · Molecules and Cells · doi:10.1016/s1016-8478(23)13057-3 · Cited by 28 · see citing works

Calcineurin Regulates Enteric Muscle Contraction Through EXP-1, Excitatory GABA-gated Channel, in C.elegans

Lee, J., Song, H., Jee, C., Vanoaica, L., & Ahnn, J. (2005) · Journal of Molecular Biology · doi:10.1016/j.jmb.2005.07.032 · Cited by 26 · see citing works

Neuropeptide Receptors NPR-1 and NPR-2 RegulateCaenorhabditis elegansAvoidance Response to the Plant Stress Hormone Methyl Salicylate

Luo, J., Xu, Z., Tan, Z., Zhang, Z., & Ma, L. (2014) · Genetics · doi:10.1534/genetics.114.172239 · Cited by 25 · see citing works

Hypoxia-inducible Factor-1 (HIF-1)-independent Hypoxia Response of the Small Heat Shock Protein hsp-16.1 Gene Regulated by Chromatin-remodeling Factors in the Nematode Caenorhabditis elegans

Lee, J., & Lee, J. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.401554 · Cited by 25 · see citing works

Signaling in the Chemosensory Systems

Bergamasco, C., & Bazzicalupo, P. (2006) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-006-6114-7 · Cited by 25 · see citing works

Regulation of Calcineurin, a Calcium/Calmodulin-dependent Protein Phosphatase, in C. elegans

Bandyopadhyay, J., Lee, J., & Bandyopadhyay, A. (2004) · Molecules and Cells · doi:10.1016/s1016-8478(23)13075-5 · Cited by 24 · see citing works

Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans

Yang, Z., Chen, J., Lu, Y.-Y., Lu, M., Wan, Q.-L., Wu, G.-S., & Luo, H. (2020) · Cell Calcium · doi:10.1016/j.ceca.2020.102327 · Cited by 23 · see citing works

Receptor Guanylyl Cyclases in Sensory Processing

MARUYAMA, I. N. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2016.00173 · Cited by 24 · see citing works

Serotonin Disinhibits aCaenorhabditis elegansSensory Neuron by Suppressing Ca2+-Dependent Negative Feedback

Williams, P., Zahratka, J. A., Rodenbeck, M., Wanamaker, J., Linzie, H., & Bamber, B. A. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1908-17.2018 · Cited by 24 · see citing works

The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in <i>Caenorhabditis elegans</i>

Fujiwara, M., Hino, T., Miyamoto, R., Inada, H., Mori, I., Koga, M., Miyahara, K., Ohshima, Y., & Ishihara, T. (2015) · Genetics · doi:10.1534/genetics.115.177543 · Cited by 23 · see citing works

Neuronal subclass-selective proteomic analysis in Caenorhabditis elegans

Aburaya, S., Yamauchi, Y., Hashimoto, T., Minakuchi, H., Aoki, W., & Ueda, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-70692-w · Cited by 23 · see citing works

Molecular mechanism for trimetric G protein-coupled thermosensation and synaptic regulation in the temperature response circuit of Caenorhabditis elegans

Ohta, A., & Kuhara, A. (2013) · Neuroscience Research · doi:10.1016/j.neures.2013.03.008 · Cited by 23 · see citing works

Calcineurin Subunits A and B Interact to Regulate Growth and Asexual and Sexual Development in Neurospora crassa

Tamuli, R., Deka, R., & Borkovich, K. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151867 · Cited by 23 · see citing works

The multiple faces of calcineurin signaling in Caenorhabditis elegans: Development, behaviour and aging

Lee, J. I., Mukherjee, S., Yoon, K.-H., Dwivedi, M., & Bandyopadhyay, J. (2013) · Journal of Biosciences · doi:10.1007/s12038-013-9319-6 · Cited by 23 · see citing works

Active propagation of dendritic electrical signals in C. elegans

Shindou, T., Ochi-Shindou, M., Murayama, T., Saita, E., Momohara, Y., Wickens, J. R., & MARUYAMA, I. N. (2019) · Scientific Reports · doi:10.1038/s41598-019-40158-9 · Cited by 22 · see citing works

Intraflagellar Transport/Hedgehog-Related Signaling Components Couple Sensory Cilium Morphology and Serotonin Biosynthesis inCaenorhabditis elegans

Moussaif, M., & Sze, J. Y. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.0044-09.2009 · Cited by 23 · see citing works

Morphological Characterization of small, dumpy, and long Phenotypes in Caenorhabditis elegans

Cho, J. Y., Choi, T.-W., Kim, S. H., Ahnn, J., & Lee, S.-K. (2021) · Molecules and Cells · doi:10.14348/molcells.2021.2236 · Cited by 19 · see citing works

Novel and Conserved Protein Macoilin Is Required for Diverse Neuronal Functions in Caenorhabditis elegans

Miyara, A., Ohta, A., Okochi, Y., Tsukada, Y., Kuhara, A., & Mori, I. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1001384 · Cited by 17 · see citing works

Regulator of Calcineurin (RCAN-1) Regulates Thermotaxis Behavior in Caenorhabditis elegans

Li, W., Bell, H. W., Ahnn, J., & Lee, S.-K. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.07.017 · Cited by 16 · see citing works

Identification and Characterization of a Putative Basic Helix-Loop-Helix (bHLH) Transcription Factor Interacting with Calcineurin in C. elegans

Lee, S., Song, H., Lee, W., Singaravelu, G., Yu, J.-R., & Park, W. (2009) · Molecules and Cells · doi:10.1007/s10059-009-0145-5 · Cited by 15 · see citing works

CNP-1 (ARRD-17), a Novel Substrate of Calcineurin, Is Critical for Modulation of Egg-Laying and Locomotion in Response to Food and Lysine Sensation in Caenorhabditis elegans

Jee, C., Choi, T.-W., Kalichamy, K., Yee, J. Z., Song, H., Ji, Y. J., Lee, J., Lee, J. I., L’Étoile, N. D., Ahnn, J., et al. (2012) · Journal of Molecular Biology · doi:10.1016/j.jmb.2012.01.012 · Cited by 14 · see citing works

Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signalingPreprint

Das, P., Aballay, A., & Singh, J. (2023) · eLife · doi:10.7554/elife.89572 · Cited by 15 · see citing works

Calcineurin and Protein kinase G regulate C. elegans behavioral quiescence during locomotion in liquid

Ghosh, R., & Emmons, S. W. (2010) · BMC Genetics · doi:10.1186/1471-2156-11-7 · Cited by 13 · see citing works

A NEUROGENETICIST'S MANIFESTO

Hall, J. C. (2003) · Journal of Neurogenetics · doi:10.1080/01677060390230349 · Cited by 14 · see citing works

A synergistic approach towards understanding the functional significance of dopamine receptor interactions

Pandey, P., Mersha, M. D., & Dhillon, H. S. (2013) · Journal of Molecular Signaling · doi:10.1186/1750-2187-8-13 · Cited by 14 · see citing works

Regulation of body size in Caenorhabditis elegans: effects of environmental factors and the nervous system

Nagashima, T., Ishiura, S., & Suo, S. (2017) · The International Journal of Developmental Biology · doi:10.1387/ijdb.160352ss · Cited by 13 · see citing works

Bacterial diet affects the age-dependent decline of associative learning in Caenorhabditis elegans

Higurashi, S., Tsukada, S., Aleogho, B. M., Park, J. H., Al-Hebri, Y., Tanaka, M., Nakano, S., Mori, I., & Noma, K. (2023) · eLife · doi:10.7554/elife.81418 · Cited by 12 · see citing works

Functional and phenotypic relevance of differentially expressed proteins in calcineurin mutants of Caenorhabditis elegans

Ahn, D., Singaravelu, G., Lee, S., Ahnn, J., & Shim, Y. (2006) · PROTEOMICS · doi:10.1002/pmic.200500315 · Cited by 12 · see citing works

Neuronal calmodulin levels are controlled by CAMTA transcription factors

Vuong-Brender, T. T. K., Flynn, S. M., Vallis, Y., Sönmez, S. E., & de Bono, M. (2021) · eLife · doi:10.7554/elife.68238 · Cited by 11 · see citing works

Calcineurin interacts with KIN-29, a Ser/Thr kinase, in Caenorhabditis elegans

Singaravelu, G., Song, H., Ji, Y. J., Jee, C., Park, B.-J., & Ahnn, J. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.10.120 · Cited by 11 · see citing works

Calcineurin Antagonizes AMPK to Regulate Lipolysis in Caenorhabditis elegans

Wang, Y., Xie, C., Diao, Z., & Liang, B. (2017) · Molecules · doi:10.3390/molecules22071062 · Cited by 11 · see citing works

Microcystins Alter Chemotactic Behavior in Caenorhabditis elegans by Selectively Targeting the AWA Sensory Neuron

Moore, C., Lein, P. J., & Puschner, B. (2014) · Toxins · doi:10.3390/toxins6061813 · Cited by 10 · see citing works

The Caenorhabditis elegans INX‐4/Innexin is required for the fine‐tuning of temperature orientation in thermotaxis behavior

Tsukamoto, S., Emmei, T., Nakano, S., Nishio, N., Sasakura, H., & Mori, I. (2020) · Genes to Cells · doi:10.1111/gtc.12745 · Cited by 10 · see citing works

WNT regulates programmed muscle remodeling through PLC-β and calcineurin in C. elegans males

LeBoeuf, B., Chen, X., & Garcia, L. R. (2020) · Development · doi:10.1242/dev.181305 · Cited by 9 · see citing works

Calcineurin TAX-6 acts as negative regulator and gain-controller in C. elegans sensory neurons

久原, 篤. (2004) · 名古屋大学 eBooks

CNP-1 (ARRD-17), a Novel Substrate of Calcineurin, Is Critical for Modulation of Egg-Laying and Locomotion in Response to Food and Lysine Sensation in Caenorhabditis elegans

Jee, C., Choi, T.-W., Kalichamy, K., Yee, J. Z., Song, H., Ji, Y. J., Lee, J., Lee, J. I., L’Étoile, N. D., Ahnn, J., et al. (2012) · Journal of Molecular Biology · doi:10.1016/j.jmb.2012.01.012 · Cited by 14 · see citing works

Regulator of Calcineurin (RCAN-1) Regulates Thermotaxis Behavior in Caenorhabditis elegans

Li, W., Bell, H. W., Ahnn, J., & Lee, S.-K. (2015) · Journal of Molecular Biology · doi:10.1016/j.jmb.2015.07.017 · Cited by 16 · see citing works

A GPCR negative feedback loop underlies efficient coding of external stimuliPreprint

Ruach, R., Yellinek, S., Itskovits, E., & Zaslaver, A. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.12.14.422627

Mutations in a Cyclic Nucleotide–Gated Channel Lead to Abnormal Thermosensation and Chemosensation in C. elegans

Komatsu, H., Mori, I., Rhee, J.-S., Akaike, N., & Ohshima, Y. (1996) · Neuron · doi:10.1016/s0896-6273(00)80202-0 · Cited by 446 · see citing works