Functional Imaging of Perceptual Learning in Human Primary and Secondary Somatosensory Cortex
Open accessAbstract
Cellular mechanisms underlying synaptic plasticity are in line with the Hebbian concept. In contrast, data linking Hebbian learning to altered perception are rare. Combining functional magnetic resonance imaging with psychophysical tests, we studied cortical reorganization in primary and secondary somatosensory cortex (SI and SII) and the resulting changes of tactile perception before and after tactile coactivation, a simple type of Hebbian learning. Coactivation on the right index finger (IF) for 3 hr lowered its spatial discrimination threshold. In parallel, blood-oxygen level-dependent (BOLD) signals from the right IF representation in SI and SII enlarged. The individual threshold reduction was linearly correlated with the enlargement in SI, implying a close relation between altered discrimination and cortical reorganization. Controls consisting of a single-site stimulation did not affect thresholds and cortical maps. Accordingly, changes within distributed cortical networks based on Hebbian mechanisms alter the individual percept.
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Early visual cortical areas are distinguished from primary somatosensory and auditory cortices, which in both monkeys and humans can show dramatic changes with perceptual learning.
“Our results also further distinguish early visual cortical areas from primary somatosensory and auditory cortices, which in both monkeys and humans can show dramatic changes with perceptual learning5, 6, 37–39.”
From Neural correlates of perceptual learning in a sensory-motor, but not a sensory, cortical area (2008) · cites this paper as [37]
Primary somatosensory and auditory cortices in monkeys and humans can show dramatic changes with perceptual learning.
“primary somatosensory and auditory cortices, which in both monkeys and humans can show dramatic changes with perceptual learning5, 6, 37–39.”
From Neural correlates of perceptual learning in a sensory-motor, but not a sensory, cortical area (2008) · cites this paper as [37]
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- Authors
- Pleger, B., Foerster, A.-F., Ragert, P., Dinse, H. R., Schwenkreis, P., Malin, J.-P., Nicolas, V., & Tegenthoff, M.
- Affiliations
- BG University Hospital Bergmannsheil Bochum (DE)
- Ruhr University Bochum (DE)
- Corresponding author
- Dinse, Hubert R
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2003-10
- Volume
- 40
- Issue
- 3
- Pages
- 643-653
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2129375705
- Cited by
- 247
- References
- 40
- Citations by year
- 2026: 4 · 2025: 7 · 2024: 11 · 2023: 9 · 2022: 9 · 2021: 13 · 2020: 13 · 2019: 13 · 2018: 10 · 2017: 8 · 2016: 13 · 2015: 17 · 2014: 13 · 2013: 13 · 2012: 10
- FWCI
- 4.73
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Keywords
- perceptual learning, Hebbian learning, synaptic plasticity, primary somatosensory cortex, secondary somatosensory cortex, cortical reorganization, BOLD signal, tactile perception, distributed cortical networks
- MeSH terms
- Adult, Brain Mapping, Choice Behavior, Differential Threshold, Female, Fingers, Humans, Image Processing, Computer-Assisted, Functional Laterality, Learning, Magnetic Resonance Imaging, Male, Oxygen, Perception, Physical Stimulation, Psychophysiology, Somatosensory Cortex, Statistics as Topic, Signal Detection, Psychological
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