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Cited by 778Tactile and Sensory InteractionsMotor Control and AdaptationMultisensory perception and integration

Topographic reorganization of the hand representation in cortical area 3b owl monkeys trained in a frequency-discrimination task

Recanzone, G. H., Merzenich, M. M., Jenkins, W. M., Grajski, K. A., Dinse, H. R.·1992·Journal of Neurophysiology
DOI 10.1152/jn.1992.67.5.1031
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Abstract

1. Adult owl monkeys were trained to detect differences in the frequency of a tactile flutter-vibration stimulus above a 20-Hz standard. All stimuli were delivered to a constant skin site restricted to a small part of a segment of one finger. The frequency-difference discrimination performance of all but one of these monkeys improved progressively with training. 2. The distributed responses of cortical neurons ("maps") of the hand surfaces were defined in detail in somatosensory cortical area 3b. Representations of trained hands were compared with those of the opposite, untrained hand, and to the area 3b representations of hands in a second set of monkeys that were stimulated tactually in the same manner while these monkeys were attending to auditory stimuli (passive stimulation controls). 3. The cortical representations of the trained hands were substantially more complex in topographic detail than the representations of unstimulated hands or of passively stimulated control hands. 4. In all well-trained monkeys the representations of the restricted skin location trained in the behavioral task were significantly (1.5 to greater than 3 times) greater in area than were the representations of equivalent skin locations on control digits. However, the overall extents of the representations of behaviorally stimulated fingers were not larger than those of control fingers in the same hemisphere, or in opposite hemisphere controls. 5. The receptive fields representing the trained skin were significantly larger than receptive fields representing control digits in all but one trained monkey. The largest receptive fields were centered in the zone of representation of the behaviorally engaged skin, but they were not limited to it. Large receptive fields were recorded in a 1- to 2-mm-wide zone in the area 3b maps of trained hands. 6. Receptive-field sizes were also statistically significantly larger on at least one adjacent, untrained digit when compared with the receptive fields recorded on the homologous digit of the opposite hand. 7. There was an increase in the percent overlaps of receptive fields in the cortical zone of representation of the trained skin. A significant number of receptive fields were centered on the behaviorally trained skin site. 8. The effects of increased topographic complexity, increased representation of the trained skin location, increased receptive-field size, and increased receptive-field overlap were not observed in the representations of the untrained hands in these same monkeys. Only modest increases in topographic complexity were recorded in the representations of passively stimulated hands, and no effects on receptive-field size or overlap were noted.(ABSTRACT TRUNCATED AT 400 WORDS)

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Crossref · 10.1152/jn.1992.67.5.1031

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  • Primary somatosensory and auditory cortices in monkeys and humans can show dramatic changes with perceptual learning.

    “primary somatosensory and auditory cortices, which in both monkeys and humans can show dramatic changes with perceptual learning5, 6, 37–39.”

    From Neural correlates of perceptual learning in a sensory-motor, but not a sensory, cortical area (2008) · cites this paper as [6]

  • Early visual cortical areas are distinguished from primary somatosensory and auditory cortices, which in both monkeys and humans can show dramatic changes with perceptual learning.

    “Our results also further distinguish early visual cortical areas from primary somatosensory and auditory cortices, which in both monkeys and humans can show dramatic changes with perceptual learning5, 6, 37–39.”

    From Neural correlates of perceptual learning in a sensory-motor, but not a sensory, cortical area (2008) · cites this paper as [6]

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Authors
Recanzone, G. H., Merzenich, M. M., Jenkins, W. M., Grajski, K. A., & Dinse, H. R.
Affiliations
University of California, San Francisco (US)
ORCID
Venue
Journal of Neurophysiology
Publisher
American Physiological Society
Published
1992-05-01
Volume
67
Issue
5
Pages
1031-1056
ISSN
  • 0022-3077 (ISSN-L)
  • 1522-1598
DOI
10.1152/jn.1992.67.5.1031
OpenAlex
W2114749031
Cited by
778
References
48
Citations by year
2026: 8 · 2025: 6 · 2024: 9 · 2023: 6 · 2022: 9 · 2021: 12 · 2020: 13 · 2019: 12 · 2018: 11 · 2017: 16 · 2016: 22 · 2015: 16 · 2014: 23 · 2013: 25 · 2012: 20
FWCI
11.45
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Neurophysiology (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institute of General Medical Sciences (T32GM007449, GM 07449)
  • National Institute of Neurological Disorders and Stroke (NS10414)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Tactile and Sensory Interactions
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Multisensory perception and integration
Keywords
somatosensory cortex, area 3b, owl monkey, receptive fields, hand representation, receptive field overlap, receptive field size, behavioral training, auditory attention
MeSH terms
Animals, Behavior, Animal, Brain Mapping, Differential Threshold, Discrimination Learning, Electric Stimulation, Electrophysiology, Hand, Neuronal Plasticity, Physical Stimulation, Skin Physiological Phenomena, Somatosensory Cortex, Aotidae

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